Complement-dependent cytotoxicity in neuromyelitis optica requires aquaporin-4 protein assembly in orthogonal arrays

Journal of Biological Chemistry

Volumn 287, Issue 17, 2012, Pages 13829-13839

  Phuan, Puay Wah ^a   Ratelade, Julien ^a   Rossi, Andrea ^a   Tradtrantip, Lukmanee ^a   Verkman, A S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY-DEPENDENT CELL-MEDIATED CYTOTOXICITIES; AUTOANTIBODIES; BINDING AFFINITIES; CELL LINES; CENTRAL NERVOUS SYSTEMS; COMPLEMENT-DEPENDENT CYTOTOXICITIES; CYTOTOXICITY ASSAYS; LACTATE DEHYDROGENASE; MULTIVALENT BINDING; NATURAL KILLER CELLS; NEW MECHANISMS; ORTHOGONAL ARRAY; PROTEIN ASSEMBLY; TETRAMERS;

BINDING ENERGY; CELL CULTURE; CELL DEATH; OLIGOMERS; PATHOLOGY;

CYTOTOXICITY;

AQUAPORIN 4; COMPLEMENT COMPONENT C1Q; IMMUNOGLOBULIN G; LACTATE DEHYDROGENASE;

ANTIGEN BINDING; ARTICLE; CELL DEATH; COMPLEMENT DEPENDENT CYTOTOXICITY; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME RELEASE; GENE DISRUPTION; HUMAN; HUMAN CELL; MYELOOPTIC NEUROPATHY; NATURAL KILLER CELL; NEUROPATHOLOGY; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN MICROARRAY; PROTEIN PROTEIN INTERACTION;

ANIMALS; AQUAPORIN 4; ASTROCYTES; AUTOANTIBODIES; CELL LINE, TUMOR; CHO CELLS; COMPLEMENT ACTIVATION; COMPLEMENT C1Q; COMPLEMENT SYSTEM PROTEINS; CRICETINAE; CRICETULUS; HUMANS; IMMUNOGLOBULIN G; NEUROMYELITIS OPTICA; PROTEIN BINDING;

EID: 84859956543     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.344325     Document Type: Article

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