-
2
-
-
48549098902
-
The pathogenesis and imaging of the tuberous sclerosis complex
-
H.J. Baskin Jr. The pathogenesis and imaging of the tuberous sclerosis complex Pediatr Radiol 38 2008 936 952
-
(2008)
Pediatr Radiol
, vol.38
, pp. 936-952
-
-
Baskin, Jr.H.J.1
-
4
-
-
34247164656
-
Tuberous sclerosis complex and epilepsy: Recent developments and future challenges
-
DOI 10.1111/j.1528-1167.2007.01035.x
-
G.L. Holmes, and C.E. Stafstrom Tuberous sclerosis complex and epilepsy: Recent developments and future challenges Epilepsia 48 2007 617 630 (Pubitemid 46587608)
-
(2007)
Epilepsia
, vol.48
, Issue.4
, pp. 617-630
-
-
Holmes, G.L.1
Stafstrom, C.E.2
Baraban, S.C.3
Bertram, E.4
Bolton, P.5
Brooks-Kayal, A.6
Chugani, H.T.7
Coulter, D.8
Crino, P.9
Delanerolle, N.C.10
Devinsky, O.11
Jacobs, M.12
Jensen, F.E.13
Kapur, J.14
Khazipov, R.15
Kirchstein, T.16
Lonsdale, J.17
Mathern, G.18
Riviello, J.19
Sahin, M.20
Sands, T.21
Sankar, R.22
Schauwecker, P.23
Staley, K.24
Talos, D.25
Thiele, E.26
Taylor, N.27
Dunigan, C.28
Whittemore, V.H.29
more..
-
6
-
-
0032438210
-
Tuberous sclerosis complex consensus conference: Revised clinical diagnostic criteria
-
E.S. Roach, M.R. Gomez, and H. Northrup Tuberous sclerosis complex consensus conference: Revised clinical diagnostic criteria J Child Neurol 13 1998 624 628 (Pubitemid 29035481)
-
(1998)
Journal of Child Neurology
, vol.13
, Issue.12
, pp. 624-628
-
-
Roach, E.S.1
Gomez, M.R.2
Northrup, H.3
-
7
-
-
8844247121
-
Brain abnormalities in tuberous sclerosis complex
-
F.J. DiMario Jr. Brain abnormalities in tuberous sclerosis complex J Child Neurol 19 2004 650 657
-
(2004)
J Child Neurol
, vol.19
, pp. 650-657
-
-
Dimario, Jr.F.J.1
-
8
-
-
78650987740
-
Tuberous sclerosis complex: Neurological, renal, and pulmonary manifestations
-
D.N. Franz, J.J. Bissler, and F.X. McCormack Tuberous sclerosis complex: Neurological, renal, and pulmonary manifestations Neuropediatrics 41 2010 199 208
-
(2010)
Neuropediatrics
, vol.41
, pp. 199-208
-
-
Franz, D.N.1
Bissler, J.J.2
McCormack, F.X.3
-
9
-
-
37549016789
-
Mechanisms of epileptogenesis in tuberous sclerosis complex and related malformations of cortical development with abnormal glioneuronal proliferation
-
M. Wong Mechanisms of epileptogenesis in tuberous sclerosis complex and related malformations of cortical development with abnormal glioneuronal proliferation Epilepsia 49 2008 8 21
-
(2008)
Epilepsia
, vol.49
, pp. 8-21
-
-
Wong, M.1
-
10
-
-
0036263937
-
Neuro-epileptic determinants of autism spectrum disorders in tuberous sclerosis complex
-
P.F. Bolton, R.J. Park, J.N. Higgins, P.D. Griffiths, and A. Pickles Neuro-epileptic determinants of autism spectrum disorders in tuberous sclerosis complex Brain 125 2002 1247 1255 (Pubitemid 34587134)
-
(2002)
Brain
, vol.125
, Issue.6
, pp. 1247-1255
-
-
Bolton, P.F.1
Park, R.J.2
Higgins, J.N.P.3
Griffiths, P.D.4
Pickles, A.5
-
11
-
-
77954888764
-
Targeted treatments for cognitive and neurodevelopmental disorders in tuberous sclerosis complex
-
P.J. de Vries Targeted treatments for cognitive and neurodevelopmental disorders in tuberous sclerosis complex Neurotherapeutics 7 2010 275 282
-
(2010)
Neurotherapeutics
, vol.7
, pp. 275-282
-
-
De Vries, P.J.1
-
12
-
-
73449090138
-
Diffusion features of white matter in tuberous sclerosis with tractography
-
M.L. Krishnan, O. Commowick, and S.S. Jeste Diffusion features of white matter in tuberous sclerosis with tractography Pediatr Neurol 42 2010 101 106
-
(2010)
Pediatr Neurol
, vol.42
, pp. 101-106
-
-
Krishnan, M.L.1
Commowick, O.2
Jeste, S.S.3
-
13
-
-
77949882117
-
The tuberous sclerosis complex
-
K.A. Orlova, and P.B. Crino The tuberous sclerosis complex Ann NY Acad Sci 1184 2010 87 105
-
(2010)
Ann NY Acad Sci
, vol.1184
, pp. 87-105
-
-
Orlova, K.A.1
Crino, P.B.2
-
14
-
-
33750593151
-
Renal manifestations of tuberous sclerosis complex: Incidence, prognosis, and predictive factors
-
DOI 10.1038/sj.ki.5001853, PII 5001853
-
S.K. Rakowski, E.B. Winterkorn, E. Paul, D.J. Steele, E.F. Halpern, and E.A. Thiele Renal manifestations of tuberous sclerosis complex: Incidence, prognosis, and predictive factors Kidney Int 70 2006 1777 1782 (Pubitemid 44684809)
-
(2006)
Kidney International
, vol.70
, Issue.10
, pp. 1777-1782
-
-
Rakowski, S.K.1
Winterkorn, E.B.2
Paul, E.3
Steele, D.J.R.4
Halpern, E.F.5
Thiele, E.A.6
-
15
-
-
0030880172
-
A large TSC2 and PKD1 gene deletion is associated with renal and extrarenal signs of autosomal dominant polycystic kidney disease
-
DOI 10.1093/ndt/12.9.1900
-
L. Longa, F. Scolari, and A. Brusco A large TSC2 and PKD1 gene deletion is associated with renal and extrarenal signs of autosomal dominant polycystic kidney disease Nephrol Dial Transplant 12 1997 1900 1907 (Pubitemid 27379463)
-
(1997)
Nephrology Dialysis Transplantation
, vol.12
, Issue.9
, pp. 1900-1907
-
-
Longa, L.1
Scolari, F.2
Brusco, A.3
Carbonara, C.4
Polidoro, S.5
Valzorio, B.6
Riegler, P.7
Migone, N.8
Maiorca, R.9
-
16
-
-
77954510897
-
Emerging evidence of a link between the polycystins and the mTOR pathways
-
A. Boletta Emerging evidence of a link between the polycystins and the mTOR pathways Pathogenetics 2 2009 6
-
(2009)
Pathogenetics
, vol.2
, pp. 6
-
-
Boletta, A.1
-
17
-
-
21344472605
-
Tuberous sclerosis and the kidney: From mesenchyme to epithelium, and beyond
-
DOI 10.1007/s00467-004-1795-3
-
E.P. Henske Tuberous sclerosis and the kidney: From mesenchyme to epithelium, and beyond Pediatr Nephrol 20 2005 854 857 (Pubitemid 40909251)
-
(2005)
Pediatric Nephrology
, vol.20
, Issue.7
, pp. 854-857
-
-
Henske, E.P.1
-
18
-
-
0035881089
-
Mutational and radiographic analysis of pulmonary disease consistent with lymphangioleiomyomatosis and micronodular pneumocyte hyperplasia in women with tuberous sclerosis
-
D.N. Franz, A. Brody, and C. Meyer Mutational and radiographic analysis of pulmonary disease consistent with lymphangioleiomyomatosis and micronodular pneumocyte hyperplasia in women with tuberous sclerosis Am J Respir Crit Care Med 164 2001 661 668 (Pubitemid 32801674)
-
(2001)
American Journal of Respiratory and Critical Care Medicine
, vol.164
, Issue.4
, pp. 661-668
-
-
Franz, D.N.1
Brody, A.2
Meyer, C.3
Leonard, J.4
Chuck, G.5
Dabora, S.6
Sethuraman, G.7
Colby, T.V.8
Kwiatkowski, D.J.9
McCormack, F.X.10
-
19
-
-
62449318120
-
Estrogen promotes the survival and pulmonary metastasis of tuberin-null cells
-
J.J. Yu, V.A. Robb, and T.A. Morrison Estrogen promotes the survival and pulmonary metastasis of tuberin-null cells Proc Natl Acad Sci USA 106 2009 2635 2640
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 2635-2640
-
-
Yu, J.J.1
Robb, V.A.2
Morrison, T.A.3
-
20
-
-
79955510505
-
Efficacy and safety of sirolimus in lymphangioleiomyomatosis
-
F.X. McCormack, Y. Inoue, and J. Moss Efficacy and safety of sirolimus in lymphangioleiomyomatosis N Engl J Med 364 2011 1595 1606
-
(2011)
N Engl J Med
, vol.364
, pp. 1595-1606
-
-
McCormack, F.X.1
Inoue, Y.2
Moss, J.3
-
21
-
-
8844236164
-
Non-neurologic manifestations of tuberous sclerosis complex
-
D.N. Franz Non-neurologic manifestations of tuberous sclerosis complex J Child Neurol 19 2004 690 698 (Pubitemid 39530079)
-
(2004)
Journal of Child Neurology
, vol.19
, Issue.9
, pp. 690-698
-
-
Franz, D.N.1
-
23
-
-
39049083046
-
Clinical presentation and diagnosis of tuberous sclerosis complex in infancy
-
DOI 10.1177/0883073807309250
-
A.N. Datta, C.D. Hahn, and M. Sahin Clinical presentation and diagnosis of tuberous sclerosis complex in infancy J Child Neurol 23 2008 268 273 (Pubitemid 351247618)
-
(2008)
Journal of Child Neurology
, vol.23
, Issue.3
, pp. 268-273
-
-
Datta, A.N.1
Hahn, C.D.2
Sahin, M.3
-
24
-
-
0036783589
-
Contemporary diagnosis and management of renal angiomyolipoma
-
C.P. Nelson, and M.G. Sanda Contemporary diagnosis and management of renal angiomyolipoma J Urol 168 2002 1315 1325 (Pubitemid 35034114)
-
(2002)
Journal of Urology
, vol.168
, Issue.4
, pp. 1315-1325
-
-
Nelson, C.P.1
Sanda, M.G.2
-
25
-
-
0023158819
-
Evidence that the gene for tuberous sclerosis is on chromosome 9
-
A.E. Fryer, A. Chalmers, and J.M. Connor Evidence that the gene for tuberous sclerosis is on chromosome 9 Lancet 1 1987 659 661
-
(1987)
Lancet
, vol.1
, pp. 659-661
-
-
Fryer, A.E.1
Chalmers, A.2
Connor, J.M.3
-
26
-
-
0026922021
-
Linkage of an important gene locus for tuberous sclerosis to a chromosome 16 marker for polycystic kidney disease
-
R.S. Kandt, J.L. Haines, and M. Smith Linkage of an important gene locus for tuberous sclerosis to a chromosome 16 marker for polycystic kidney disease Nat Genet 2 1992 37 41
-
(1992)
Nat Genet
, vol.2
, pp. 37-41
-
-
Kandt, R.S.1
Haines, J.L.2
Smith, M.3
-
27
-
-
0027770784
-
Identification and characterization of the tuberous sclerosis gene on chromosome 16
-
European Chromosome 16 Tuberous Sclerosis Consortium
-
European Chromosome 16 Tuberous Sclerosis Consortium Identification and characterization of the tuberous sclerosis gene on chromosome 16 Cell 75 1993 1305 1315
-
(1993)
Cell
, vol.75
, pp. 1305-1315
-
-
-
28
-
-
0030879277
-
Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34
-
DOI 10.1126/science.277.5327.805
-
M. van Slegtenhorst, R. de Hoogt, and C. Hermans Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34 Science 277 1997 805 808 (Pubitemid 27366729)
-
(1997)
Science
, vol.277
, Issue.5327
, pp. 805-808
-
-
Van Slegtenhorst, M.1
De Hoogt, R.2
Hermans, C.3
Nellist, M.4
Janssen, B.5
Verhoef, S.6
Lindhout, D.7
Van Den Ouweland, A.8
Halley, D.9
Young, J.10
Burley, M.11
Jeremiah, S.12
Woodward, K.13
Nahmias, J.14
Fox, M.15
Ekong, R.16
Osborne, J.17
Wolfe, J.18
Povey, S.19
Snell, R.G.20
Cheadle, J.P.21
Jones, A.C.22
Tachataki, M.23
Ravine, D.24
Sampson, J.R.25
Reeve, M.P.26
Richardson, P.27
Wilmer, F.28
Munro, C.29
Hawkins, T.L.30
Sepp, T.31
Ali, J.B.M.32
Ward, S.33
Green, A.J.34
Yates, J.R.W.35
Kwiatkowska, J.36
Henske, E.P.37
Short, M.P.38
Haines, J.H.39
Jozwiak, S.40
Kwiatkowski, D.J.41
more..
-
29
-
-
8844286824
-
Molecular genetic basis of tuberous sclerosis complex: From bench to bedside
-
K.S. Au, A.T. Williams, M.J. Gambello, and H. Northrup Molecular genetic basis of tuberous sclerosis complex: From bench to bedside J Child Neurol 19 2004 699 709 (Pubitemid 39530080)
-
(2004)
Journal of Child Neurology
, vol.19
, Issue.9
, pp. 699-709
-
-
Au, K.-S.1
Williams, A.T.2
Gambello, M.J.3
Northrup, H.4
-
30
-
-
58249127284
-
Recent advances in neurobiology of tuberous sclerosis complex
-
V. Napolioni, R. Moavero, and P. Curatolo Recent advances in neurobiology of tuberous sclerosis complex Brain Dev 31 2009 104 113
-
(2009)
Brain Dev
, vol.31
, pp. 104-113
-
-
Napolioni, V.1
Moavero, R.2
Curatolo, P.3
-
31
-
-
20544431744
-
Mutational analysis of the TSC1 and TSC2 genes in a diagnostic setting: Genotype-phenotype correlations and comparison of diagnostic DNA techniques in tuberous sclerosis complex
-
DOI 10.1038/sj.ejhg.5201402
-
O. Sancak, M. Nellist, and M. Goedbloed Mutational analysis of the TSC1 and TSC2 genes in a diagnostic setting: Genotype-phenotype correlations and comparison of diagnostic DNA techniques in tuberous sclerosis complex Eur J Hum Genet 13 2005 731 741 (Pubitemid 40846845)
-
(2005)
European Journal of Human Genetics
, vol.13
, Issue.6
, pp. 731-741
-
-
Sancak, O.1
Nellist, M.2
Goedbloed, M.3
Elfferich, P.4
Wouters, C.5
Maat-Kievit, A.6
Zonnenberg, B.7
Verhoef, S.8
Halley, D.9
Van Den Ouweland, A.10
-
32
-
-
79951856253
-
Evidence for population variation in TSC1 and TSC2 gene expression
-
G.M. Jentarra, S.G. Rice, S. Olfers, D. Saffen, and V. Narayanan Evidence for population variation in TSC1 and TSC2 gene expression BMC Med Genet 12 2011 29
-
(2011)
BMC Med Genet
, vol.12
, pp. 29
-
-
Jentarra, G.M.1
Rice, S.G.2
Olfers, S.3
Saffen, D.4
Narayanan, V.5
-
33
-
-
4043171462
-
Upstream and downstream of mTOR
-
DOI 10.1101/gad.1212704
-
N. Hay, and N. Sonenberg Upstream and downstream of mTOR Genes Dev 18 2004 1926 1945 (Pubitemid 39071573)
-
(2004)
Genes and Development
, vol.18
, Issue.16
, pp. 1926-1945
-
-
Hay, N.1
Sonenberg, N.2
-
34
-
-
10044276783
-
Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex
-
DOI 10.1101/gad.1256804
-
J. Brugarolas, K. Lei, and R.L. Hurley Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex Genes Dev 18 2004 2893 2904 (Pubitemid 39602308)
-
(2004)
Genes and Development
, vol.18
, Issue.23
, pp. 2893-2904
-
-
Brugarolas, J.1
Lei, K.2
Hurley, R.L.3
Manning, B.D.4
Reiling, J.H.5
Hafen, E.6
Witters, L.A.7
Ellisen, L.W.8
Kaelin Jr., W.G.9
-
35
-
-
27744588780
-
Tuberous sclerosis: A GAP at the crossroads of multiple signaling pathways
-
DOI 10.1093/hmg/ddi260
-
D.J. Kwiatkowski, and B.D. Manning Tuberous sclerosis: A GAP at the crossroads of multiple signaling pathways Hum Mol Genet 14 2005 R251 R258 (Pubitemid 41631882)
-
(2005)
Human Molecular Genetics
, vol.14
, Issue.SUPPL. 2
-
-
Kwiatkowski, D.J.1
Manning, B.D.2
-
36
-
-
33749431713
-
The mTOR pathway in the control of protein synthesis
-
DOI 10.1152/physiol.00024.2006
-
X. Wang, and C.G. Proud The mTOR pathway in the control of protein synthesis Physiology 21 2006 362 369 (Pubitemid 44511764)
-
(2006)
Physiology
, vol.21
, Issue.5
, pp. 362-369
-
-
Wang, X.1
Proud, C.G.2
-
37
-
-
39049185811
-
Growth control under stress: MTOR regulation through the REDD1-TSC pathway
-
L.W. Ellisen Growth control under stress: mTOR regulation through the REDD1-TSC pathway Cell Cycle 4 2005 1500 1502
-
(2005)
Cell Cycle
, vol.4
, pp. 1500-1502
-
-
Ellisen, L.W.1
-
38
-
-
44449161481
-
The TSC1-TSC2 complex: A molecular switchboard controlling cell growth
-
DOI 10.1042/BJ20080281
-
J. Huang, and B.D. Manning The TSC1-TSC2 complex: A molecular switchboard controlling cell growth Biochem J 412 2008 179 190 (Pubitemid 351758225)
-
(2008)
Biochemical Journal
, vol.412
, Issue.2
, pp. 179-190
-
-
Huang, J.1
Manning, B.D.2
-
39
-
-
43049131769
-
Targeting the PI3K/Akt/mTOR pathway: Effective combinations and clinical considerations
-
J. LoPiccolo, G.M. Blumenthal, W.B. Bernstein, and P.A. Dennis Targeting the PI3K/Akt/mTOR pathway: Effective combinations and clinical considerations Drug Resist Update 11 2008 32 50
-
(2008)
Drug Resist Update
, vol.11
, pp. 32-50
-
-
Lopiccolo, J.1
Blumenthal, G.M.2
Bernstein, W.B.3
Dennis, P.A.4
-
40
-
-
38149062059
-
Role of mTOR in physiology and pathology of the nervous system
-
L. Swiech, M. Perycz, A. Malik, and J. Jaworski Role of mTOR in physiology and pathology of the nervous system Biochim Biophys Acta 1784 2008 116 132
-
(2008)
Biochim Biophys Acta
, vol.1784
, pp. 116-132
-
-
Swiech, L.1
Perycz, M.2
Malik, A.3
Jaworski, J.4
-
41
-
-
34547168930
-
The tuberous sclerosis complex proteins - A GRIPP on cognition and neurodevelopment
-
DOI 10.1016/j.molmed.2007.06.003, PII S1471491407001086
-
P.J. de Vries, and C.J. Howe The tuberous sclerosis complex proteins: A GRIPP on cognition and neurodevelopment Trends Mol Med 13 2007 319 326 (Pubitemid 47126986)
-
(2007)
Trends in Molecular Medicine
, vol.13
, Issue.8
, pp. 319-326
-
-
De Vries, P.J.1
Howe, C.J.2
-
42
-
-
10044259616
-
Pathogenesis of tuberous sclerosis subependymal giant cell astrocytomas: Biallelic inactivation of TSC1 or TSC2 leads to mTOR activation
-
J.A. Chan, and H. Zang Pathogenesis of tuberous sclerosis subependymal giant cell astrocytomas: Biallelic inactivation of TSC1 or TSC2 leads to mTOR activation J Neuropathol Exp Neurol 63 2004 1236 1242 (Pubitemid 39603395)
-
(2004)
Journal of Neuropathology and Experimental Neurology
, vol.63
, Issue.12
, pp. 1236-1242
-
-
Chan, J.A.1
Zhang, H.2
Roberts, P.S.3
Jozwiak, S.4
Wieslawa, G.5
Lewin-Kowalik, J.6
Kotulska, K.7
Kwiatkowski, D.J.8
-
43
-
-
78649330303
-
Epilepsy secondary to tuberous sclerosis: Lessons learned and current challenges
-
R. Moavero, C. Cerminara, and P. Curatolo Epilepsy secondary to tuberous sclerosis: Lessons learned and current challenges Childs Nerv Syst 26 2010 1495 1504
-
(2010)
Childs Nerv Syst
, vol.26
, pp. 1495-1504
-
-
Moavero, R.1
Cerminara, C.2
Curatolo, P.3
-
44
-
-
59749096847
-
Therapeutic targeting of mTOR in tuberous sclerosis
-
J.R. Sampson Therapeutic targeting of mTOR in tuberous sclerosis Biochem Soc Trans 37 2009 259 264
-
(2009)
Biochem Soc Trans
, vol.37
, pp. 259-264
-
-
Sampson, J.R.1
-
45
-
-
77957994045
-
Perspectives on inhibiting mTOR as a future treatment strategy for hematological malignancies
-
N. Chapuis, J. Tamburini, and A.S. Green Perspectives on inhibiting mTOR as a future treatment strategy for hematological malignancies Leukemia 24 2010 1686 1699
-
(2010)
Leukemia
, vol.24
, pp. 1686-1699
-
-
Chapuis, N.1
Tamburini, J.2
Green, A.S.3
-
46
-
-
68949102180
-
Phase III study to evaluate temsirolimus compared with investigator's choice therapy for the treatment of relapsed or refractory mantle cell lymphoma
-
G. Hess, R. Herbrecht, and J. Romaguera Phase III study to evaluate temsirolimus compared with investigator's choice therapy for the treatment of relapsed or refractory mantle cell lymphoma J Clin Oncol 27 2009 3822 3829
-
(2009)
J Clin Oncol
, vol.27
, pp. 3822-3829
-
-
Hess, G.1
Herbrecht, R.2
Romaguera, J.3
-
47
-
-
77957659746
-
Everolimus: A proliferation signal inhibitor with clinical applications in organ transplantation, oncology, and cardiology
-
S. Gabardi, and S.A. Baroletti Everolimus: A proliferation signal inhibitor with clinical applications in organ transplantation, oncology, and cardiology Pharmacotherapy 30 2010 1044 1056
-
(2010)
Pharmacotherapy
, vol.30
, pp. 1044-1056
-
-
Gabardi, S.1
Baroletti, S.A.2
-
48
-
-
78049510428
-
Everolimus for subependymal giant-cell astrocytomas in tuberous sclerosis
-
D.A. Krueger, M.M. Care, and K. Holland Everolimus for subependymal giant-cell astrocytomas in tuberous sclerosis N Engl J Med 363 2010 1801 1811
-
(2010)
N Engl J Med
, vol.363
, pp. 1801-1811
-
-
Krueger, D.A.1
Care, M.M.2
Holland, K.3
-
49
-
-
0032941743
-
Early diagnosis of subependymal giant cell astrocytoma in children with tuberous sclerosis
-
R. Nabbout, M. Santos, Y. Rolland, O. Delalande, O. Dulac, and C. Chiron Early diagnosis of subependymal giant cell astrocytoma in children with tuberous sclerosis J Neurol Neurosurg Psychiatry 66 1999 370 375 (Pubitemid 29103492)
-
(1999)
Journal of Neurology Neurosurgery and Psychiatry
, vol.66
, Issue.3
, pp. 370-375
-
-
Nabbout, R.1
Santos, M.2
Rolland, Y.3
Delalande, O.4
Dulac, O.5
Chiron, C.6
-
50
-
-
38049169559
-
Sirolimus for angiomyolipoma in tuberous sclerosis complex or lymphangioleiomyomatosis
-
J.J. Bissler, F.X. McCormack, and L.R. Young Sirolimus for angiomyolipoma in tuberous sclerosis complex or lymphangioleiomyomatosis N Engl J Med 358 2008 140 151
-
(2008)
N Engl J Med
, vol.358
, pp. 140-151
-
-
Bissler, J.J.1
McCormack, F.X.2
Young, L.R.3
-
51
-
-
84859881629
-
-
ClinicalTrials.gov. Accessed February 2, 2012
-
ClinicalTrials.gov. www.clinicaltrials.gov. Accessed February 2, 2012.
-
-
-
-
52
-
-
33644827461
-
Rapamycin causes regression of astrocytomas in tuberous sclerosis complex
-
DOI 10.1002/ana.20784
-
D.N. Franz, J. Leonard, and C. Tudor Rapamycin causes regression of astrocytomas in tuberous sclerosis complex Ann Neurol 59 2006 490 498 (Pubitemid 43358069)
-
(2006)
Annals of Neurology
, vol.59
, Issue.3
, pp. 490-498
-
-
Franz, D.N.1
Leonard, J.2
Tudor, C.3
Chuck, G.4
Care, M.5
Sethuraman, G.6
Dinopoulos, A.7
Thomas, G.8
Crone, K.R.9
-
53
-
-
53549125236
-
Regression of subependymal giant cell astrocytoma with rapamycin in tuberous sclerosis complex
-
M.K. Koenig, I.J. Butler, and H. Northrup Regression of subependymal giant cell astrocytoma with rapamycin in tuberous sclerosis complex J Child Neurol 23 2008 1238 1239
-
(2008)
J Child Neurol
, vol.23
, pp. 1238-1239
-
-
Koenig, M.K.1
Butler, I.J.2
Northrup, H.3
-
54
-
-
77957922822
-
Rapamycin as an alternative to surgical treatment of subependymal giant cell astrocytomas in a patient with tuberous sclerosis complex
-
A. Birca, C. Mercier, and P. Major Rapamycin as an alternative to surgical treatment of subependymal giant cell astrocytomas in a patient with tuberous sclerosis complex J Neurosurg Pediatr 6 2010 381 384
-
(2010)
J Neurosurg Pediatr
, vol.6
, pp. 381-384
-
-
Birca, A.1
Mercier, C.2
Major, P.3
-
55
-
-
76749124339
-
Rapamycin (sirolimus) in tuberous sclerosis associated pediatric central nervous system tumors
-
C. Lam, E. Bouffet, U. Tabori, D. Mabbott, M. Taylor, and U. Bartels Rapamycin (sirolimus) in tuberous sclerosis associated pediatric central nervous system tumors Pediatr Blood Cancer 54 2010 476 479
-
(2010)
Pediatr Blood Cancer
, vol.54
, pp. 476-479
-
-
Lam, C.1
Bouffet, E.2
Tabori, U.3
Mabbott, D.4
Taylor, M.5
Bartels, U.6
-
56
-
-
33644689608
-
Molecular activity of sirolimus and its possible application in tuberous sclerosis treatment
-
DOI 10.1002/med.20049
-
J. Jozwiak, S. Jozwiak, and M. Oldak Molecular activity of sirolimus and its possible application in tuberous sclerosis treatment Med Res Rev 26 2006 160 180 (Pubitemid 43334640)
-
(2006)
Medicinal Research Reviews
, vol.26
, Issue.2
, pp. 160-180
-
-
Jozwiak, J.1
Jozwiak, S.2
Oldak, M.3
-
57
-
-
78951473590
-
Regression of subependymal giant cell astrocytomas with RAD001 (everolimus) in tuberous sclerosis complex
-
M. Yalon, L. Ben-Sira, S. Constantini, and A. Toren Regression of subependymal giant cell astrocytomas with RAD001 (everolimus) in tuberous sclerosis complex Childs Nerv Syst 27 2011 179 181
-
(2011)
Childs Nerv Syst
, vol.27
, pp. 179-181
-
-
Yalon, M.1
Ben-Sira, L.2
Constantini, S.3
Toren, A.4
-
59
-
-
76249084241
-
Mammalian target of rapamycin (mTOR) inhibition as a potential antiepileptogenic therapy: From tuberous sclerosis to common acquired epilepsies
-
M. Wong Mammalian target of rapamycin (mTOR) inhibition as a potential antiepileptogenic therapy: From tuberous sclerosis to common acquired epilepsies Epilepsia 51 2010 27 36
-
(2010)
Epilepsia
, vol.51
, pp. 27-36
-
-
Wong, M.1
-
60
-
-
70350412265
-
From mTOR to cognition: Molecular and cellular mechanisms of cognitive impairments in tuberous sclerosis
-
D. Ehninger, P.J. de Vries, and A.J. Silva From mTOR to cognition: Molecular and cellular mechanisms of cognitive impairments in tuberous sclerosis J Intellect Disabil Res 53 2009 838 851
-
(2009)
J Intellect Disabil Res
, vol.53
, pp. 838-851
-
-
Ehninger, D.1
De Vries, P.J.2
Silva, A.J.3
-
61
-
-
79651475390
-
Rapamycin for treating tuberous sclerosis and autism spectrum disorders
-
D. Ehninger, and A.J. Silva Rapamycin for treating tuberous sclerosis and autism spectrum disorders Trends Mol Med 17 2011 78 87
-
(2011)
Trends Mol Med
, vol.17
, pp. 78-87
-
-
Ehninger, D.1
Silva, A.J.2
-
63
-
-
42949140259
-
Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex
-
DOI 10.1002/ana.21331
-
L.H. Zeng, L. Xu, D.H. Gutmann, and M. Wong Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex Ann Neurol 63 2008 444 453 (Pubitemid 351614710)
-
(2008)
Annals of Neurology
, vol.63
, Issue.4
, pp. 444-453
-
-
Zeng, L.-H.1
Xu, L.2
Gutmann, D.H.3
Wong, M.4
-
64
-
-
72149109544
-
Angiomyolipomata: Challenges, solutions, and future prospects based on over 100 cases treated
-
P. Sooriakumaran, P. Gibbs, and G. Coughlin Angiomyolipomata: Challenges, solutions, and future prospects based on over 100 cases treated BJU Int 105 2010 101 106
-
(2010)
BJU Int
, vol.105
, pp. 101-106
-
-
Sooriakumaran, P.1
Gibbs, P.2
Coughlin, G.3
-
65
-
-
27544493736
-
Long-term outcome of transcatheter embolization of renal angiomyolipomas due to tuberous sclerosis complex
-
DOI 10.1097/01.ju.0000177497.31986.64
-
D.H. Ewalt, N. Diamond, and C. Rees Long-term outcome of transcatheter embolization of renal angiomyolipomas due to tuberous sclerosis complex J Urol 174 2005 1764 1766 (Pubitemid 41546930)
-
(2005)
Journal of Urology
, vol.174
, Issue.5
, pp. 1764-1766
-
-
Ewalt, D.H.1
Diamond, N.2
Rees, C.3
Sparagana, S.P.4
Delgado, M.5
Batchelor, L.6
Roach, E.S.7
-
66
-
-
33747608873
-
Antitumoral activity of rapamycin in renal angiomyolipoma associated with tuberous sclerosis complex
-
DOI 10.1053/j.ajkd.2006.05.018, PII S0272638606009516
-
R. Wienecke, I. Fackler, U. Linsenmaier, K. Mayer, T. Licht, and M. Kretzler Antitumoral activity of rapamycin in renal angiomyolipoma associated with tuberous sclerosis complex Am J Kidney Dis 48 2006 e27 e29 (Pubitemid 44262422)
-
(2006)
American Journal of Kidney Diseases
, vol.48
, Issue.3
-
-
Wienecke, R.1
Fackler, I.2
Linsenmaier, U.3
Mayer, K.4
Licht, T.5
Kretzler, M.6
-
67
-
-
79952202123
-
Low-dose rapamycin reduces kidney volume angiomyolipomas and prevents the loss of renal function in a patient with tuberous sclerosis complex
-
R. Peces, C. Peces, and E. Cuesta-Lopez Low-dose rapamycin reduces kidney volume angiomyolipomas and prevents the loss of renal function in a patient with tuberous sclerosis complex Nephrol Dial Transplant 25 2010 3787 3791
-
(2010)
Nephrol Dial Transplant
, vol.25
, pp. 3787-3791
-
-
Peces, R.1
Peces, C.2
Cuesta-Lopez, E.3
-
68
-
-
77953792808
-
Sirolimus and tuberous sclerosis-associated renal angiomyolipomas
-
L. Krischock, R. Beach, and J. Taylor Sirolimus and tuberous sclerosis-associated renal angiomyolipomas Arch Dis Child 95 2010 391 392
-
(2010)
Arch Dis Child
, vol.95
, pp. 391-392
-
-
Krischock, L.1
Beach, R.2
Taylor, J.3
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