Regression of subependymal giant cell astrocytoma with rapamycin in tuberous sclerosis complex

Journal of Child Neurology

Volumn 23, Issue 10, 2008, Pages 1238-1239

  Koenig, Kay Mary ^a   Butler, Ian J ^a   Northrup, Hope ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

Astrocytoma; Rapamycin; Subependymal giant cell astrocytoma; Tuberous sclerosis complex

Indexed keywords

RAPAMYCIN;

ABSENCE OF SIDE EFFECTS; ADULT; ASTROCYTOMA; BALANCE DISORDER; BLURRED VISION; CASE REPORT; CONFERENCE PAPER; DRUG EFFICACY; FEMALE; FOLLOW UP; HEADACHE; HUMAN; HYDROCEPHALUS; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; SUBEPENDYMAL GIANT CELL ASTROCYTOMA; TUBEROUS SCLEROSIS; TUMOR REGRESSION; TUMOR VOLUME;

ANTIBIOTICS, ANTINEOPLASTIC; BRAIN; BRAIN NEOPLASMS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GLIOMA, SUBEPENDYMAL; HUMANS; MAGNETIC RESONANCE IMAGING; SIROLIMUS; TREATMENT OUTCOME; TUBEROUS SCLEROSIS; YOUNG ADULT;

EID: 53549125236     PISSN: 08830738     EISSN: None     Source Type: Journal    
DOI: 10.1177/0883073808321764     Document Type: Conference Paper

References (4)

1. Kenerson H., Dundon TA, Yeung RS Effects of rapamycin in the Eker rat model of tuberous sclerosis complex. Pediatr Res. 2005; 57: 67-75.
2. Rauktys A., Lee N., Lee L., Dabora SL Topical rapamycin inhibits tuberous sclerosis tumor growth in a nude mouse model. BMC Dermatol. 2008; 8: 1-9.
3. Bissler JJ, McCormack FX, Young LR, et al. Sirolimus for angiomyolipoma in tuberous sclerosis complex or lymphangioleiomyomatosis. N Engl J Med. 2008; 358: 140-151.
4. Franz DN, Leonard J., Tudor C., et al. Rapamycin causes regression of astrocytomas in tuberous sclerosis complex. Ann Neurol. 2006; 59: 490-498.