Phase diagram of ternary cholesterol/palmitoylsphingomyelin/ palmitoyloleoyl-phosphatidylcholine mixtures: Spin-label EPR study of lipid-raft formation

Biophysical Journal

Volumn 102, Issue 8, 2012, Pages 1856-1865

  Ionova, Irina V ^a,b   Livshits, Vsevolod A ^a,b   Marsh, Derek ^a,b  

^a RUSSIAN ACADEMY OF SCIENCES   (Russian Federation)

^b MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

1-PALMITOYL-2-OLEOYLPHOSPHATIDYLCHOLINE; 2 OLEOYL 1 PALMITOYLPHOSPHATIDYLCHOLINE; CHOLESTEROL; PALMITOYLSPHINGOMYELIN; PHOSPHATIDYLCHOLINE; SPHINGOMYELIN;

ARTICLE; CELL MEMBRANE; CHEMISTRY; ELECTRON SPIN RESONANCE; NONLINEAR SYSTEM; SPIN LABELING;

CHOLESTEROL; ELECTRON SPIN RESONANCE SPECTROSCOPY; MEMBRANE MICRODOMAINS; NONLINEAR DYNAMICS; PHOSPHATIDYLCHOLINES; SPHINGOMYELINS; SPIN LABELS;

EID: 84859917050     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1016/j.bpj.2012.03.043     Document Type: Article

References (45)

1. K. Simons, and E. Ikonen Functional rafts in cell membranes Nature 387 1997 569 572 (Pubitemid 27248754)
2. K. Simons, and W.L. Vaz Model systems, lipid rafts, and cell membranes Annu. Rev. Biophys. Biomol. Struct. 33 2004 269 295 (Pubitemid 38829961)
3. D. Lingwood, and K. Simons Lipid rafts as a membrane-organizing principle Science 327 2010 46 50
4. 2H nuclear magnetic resonance and differential scanning calorimetry Biochemistry 29 1990 451 464 (Pubitemid 20037653)
5. J.H. Ipsen, and G. Karlström M.J. Zuckermann Phase equilibria in the phosphatidylcholine-cholesterol system Biochim. Biophys. Acta 905 1987 162 172
6. D. Marsh Liquid-ordered phases induced by cholesterol: a compendium of binary phase diagrams Biochim. Biophys. Acta 1798 2010 688 699
7. D.J. Recktenwald, and H.M. McConnell Phase equilibria in binary mixtures of phosphatidylcholine and cholesterol Biochemistry 20 1981 4505 4510
8. D. Marsh Cholesterol-induced fluid membrane domains: a compendium of lipid-raft ternary phase diagrams Biochim. Biophys. Acta 1788 2009 2114 2123
9. F.M. Goñi, and A. Alonso J.L. Thewalt Phase diagrams of lipid mixtures relevant to the study of membrane rafts Biochim. Biophys. Acta 1781 2008 665 684
10. S.L. Veatch, and S.L. Keller Separation of liquid phases in giant vesicles of ternary mixtures of phospholipids and cholesterol Biophys. J. 85 2003 3074 3083 (Pubitemid 37345795)
11. S.L. Veatch, and S.L. Keller Miscibility phase diagrams of giant vesicles containing sphingomyelin Phys. Rev. Lett. 94 2005 148101
12. o Phases Biochim. Biophys. Acta 1768 2007 2777 2786 (Pubitemid 350060871)
13. J. Zhao, and J. Wu G.W. Feigenson Phase studies of model biomembranes: complex behavior of DSPC/DOPC/cholesterol Biochim. Biophys. Acta 1768 2007 2764 2776 (Pubitemid 350060870)
14. S.L. Veatch, and O. Soubias K. Gawrisch Critical fluctuations in domain-forming lipid mixtures Proc. Natl. Acad. Sci. USA 104 2007 17650 17655 (Pubitemid 350210874)
15. 62/cholesterol mixtures Biophys. J. 96 2009 521 539
16. S.L. Veatch, K. Gawrisch, and S.L. Keller Closed-loop miscibility gap and quantitative tie-lines in ternary membranes containing diphytanoyl PC Biophys. J. 90 2006 4428 4436 (Pubitemid 43830889)
17. M.I. Collado, and F.M. Goñi D. Marsh Domain formation in sphingomyelin/cholesterol mixed membranes studied by spin-label electron spin resonance spectroscopy Biochemistry 44 2005 4911 4918 (Pubitemid 40396769)
18. M.P. Veiga, and J.L.R. Arrondo D. Marsh Interaction of cholesterol with sphingomyelin in mixed membranes containing phosphatidylcholine, studied by spin-label ESR and IR spectroscopies. A possible stabilization of gel-phase sphingolipid domains by cholesterol Biochemistry 40 2001 2614 2622 (Pubitemid 32171737)
19. Y.W. Chiang, and Y. Shimoyama J.H. Freed Dynamic molecular structure of DPPC-DLPC-cholesterol ternary lipid system by spin-label electron spin resonance Biophys. J. 87 2004 2483 2496
20. Y.W. Chiang, and J. Zhao G.W. Feigenson New method for determining tie-lines in coexisting membrane phases using spin-label ESR Biochim. Biophys. Acta 1668 2005 99 105 (Pubitemid 40164737)
21. F.A. Heberle, and J. Wu G.W. Feigenson Comparison of three ternary lipid bilayer mixtures: FRET and ESR reveal nanodomains Biophys. J. 99 2010 3309 3318
22. R.F.M. de Almeida, and L.M.S. Loura M. Prieto Lipid rafts have different sizes depending on membrane composition: a time-resolved fluorescence resonance energy transfer study J. Mol. Biol. 346 2005 1109 1120 (Pubitemid 40220330)
23. P. Pathak, and E. London Measurement of lipid nanodomain (raft) formation and size in sphingomyelin/POPC/cholesterol vesicles shows TX-100 and transmembrane helices increase domain size by coalescing preexisting nanodomains but do not induce domain formation Biophys. J. 101 2011 2417 2425
24. A.G. Ayuyan, and F.S. Cohen Lipid peroxides promote large rafts: effects of excitation of probes in fluorescence microscopy and electrochemical reactions during vesicle formation Biophys. J. 91 2006 2172 2183 (Pubitemid 44352400)
25. R.F.M. de Almeida, A. Fedorov, and M. Prieto Sphingomyelin/ phosphatidylcholine/cholesterol phase diagram: boundaries and composition of lipid rafts Biophys. J. 85 2003 2406 2416 (Pubitemid 37210789)
26. T.E. Thompson, and T.W. Tillack Organization of glycosphingolipids in bilayers and plasma membranes of mammalian cells Annu. Rev. Biophys. Biophys. Chem. 14 1985 361 386
27. A. Pokorny, and L.E. Yandek P.F. Almeida Temperature and composition dependence of the interaction of δ-lysin with ternary mixtures of sphingomyelin/cholesterol/POPC Biophys. J. 91 2006 2184 2197 (Pubitemid 44352401)
28. A.K. Smith, and J.H. Freed Determination of tie-line fields for coexisting lipid phases: an ESR study J. Phys. Chem. B 113 2009 3957 3971
29. V.A. Livshits, T. Páli, and D. Marsh Spin relaxation measurements using first-harmonic out-of-phase absorption EPR signals J. Magn. Reson. 134 1998 113 123 (Pubitemid 128451262)
30. 1 values J. Magn. Reson. 175 2005 317 329 (Pubitemid 40891687)
31. D. Marsh Electron spin resonance in membrane research: protein-lipid interactions Methods 46 2008 83 96
32. P. Fajer, and D. Marsh Microwave and modulation field inhomogeneities and the effect of cavity Q in saturation transfer ESR spectra. Dependence on sample size J. Magn. Reson. 49 1982 212 224
33. P.F. Knowles, A. Watts, and D. Marsh Spin-label studies of head-group specificity in the interaction of phospholipids with yeast cytochrome oxidase Biochemistry 20 1981 5888 5894
34. J.R. Silvius Partitioning of membrane molecules between raft and non-raft domains: insights from model-membrane studies Biochim. Biophys. Acta 1746 2005 193 202 (Pubitemid 41815016)
35. V.A. Livshits, B.G. Dzikovski, and D. Marsh Anisotropic motion effects in CW non-linear EPR spectra: relaxation enhancement of lipid spin labels J. Magn. Reson. 162 2003 429 442
36. W.K. Subczynski, and J. Widomska A. Kusumi Saturation recovery electron paramagnetic resonance discrimination by oxygen transport (DOT) method for characterizing membrane domains T.J. McIntosh, Lipid Rafts 2007 Humana Press Totowa, New Jersey 143 157
37. V.A. Livshits, B.G. Dzikovski, and D. Marsh Mechanism of relaxation enhancement of spin labels in membranes by paramagnetic ion salts: dependence on 3d and 4f ions and on the anions J. Magn. Reson. 148 2001 221 237
38. D.J. Schneider, and J.H. Freed Calculating slow motional magnetic resonance spectra: a user's guide L.J. Berliner, J. Reuben, Spin-Labeling. Theory and Applications 1989 Plenum Publishing New York 1 76
39. D.E. Budil, and S. Lee J.H. Freed Nonlinear least-squares analysis of slow-motion EPR spectra in one and two dimensions using a modified Levenberg-Marquardt algorithm J. Magn. Reson. A 120 1996 155 189 (Pubitemid 126751752)
40. V.A. Livshits, D. Kurad, and D. Marsh Multifrequency simulations of the EPR spectra of lipid spin labels in membranes J. Magn. Reson. 180 2006 63 71
41. J.L. Thewalt, and M. Bloom Phosphatidylcholine: cholesterol phase diagrams Biophys. J. 63 1992 1176 1181
42. A. Filippov, G. Orädd, and G. Lindblom The effect of cholesterol on the lateral diffusion of phospholipids in oriented bilayers Biophys. J. 84 2003 3079 3086 (Pubitemid 36534465)
43. Y.W. Hsueh, and M.T. Chen J. Thewalt Ergosterol in POPC membranes: physical properties and comparison with structurally similar sterols Biophys. J. 92 2007 1606 1615 (Pubitemid 46393471)
44. G. Cevc, and D. Marsh Phospholipid Bilayers: Physical Principles and Models 1987 Wiley-Interscience New York
45. P. Uppamoochikkal, S. Tristram-Nagle, and J.F. Nagle Orientation of tie-lines in the phase diagram of DOPC/DPPC/cholesterol model biomembranes Langmuir 26 2010 17363 17368