메뉴 건너뛰기




Volumn 117, Issue 2, 2012, Pages 113-121

On the origin of glioma

Author keywords

Astrocyte; Cell of origin; Glioma; Glioma initiating cell; Neural stem cell; Oligodendrocyte precursor cell

Indexed keywords

ANIMAL; ARTICLE; ASTROCYTE; BRAIN TUMOR; CELL LINEAGE; DISEASE MODEL; GENETICS; GLIOMA; HUMAN; MOUSE; MUTATION; PATHOLOGY;

EID: 84859903751     PISSN: 03009734     EISSN: None     Source Type: Journal    
DOI: 10.3109/03009734.2012.658976     Document Type: Article
Times cited : (73)

References (76)
  • 2
    • 54549108740 scopus 로고    scopus 로고
    • Comprehensive genomic characterization defines human glioblastoma genes and core pathways
    • Cancer Genome Atlas Research Network
    • Cancer Genome Atlas Research Network. Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature. 2008;455:1061-8.
    • (2008) Nature. , vol.455 , pp. 1061-1068
  • 4
    • 73649123907 scopus 로고    scopus 로고
    • Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
    • Verhaak RG, Hoadley KA, Purdom E, Wang V, Qi Y, Wilkerson MD, et al. Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell. 2010;17:98-110.
    • (2010) Cancer Cell. , vol.17 , pp. 98-110
    • Verhaak, R.G.1    Hoadley, K.A.2    Purdom, E.3    Wang, V.4    Qi, Y.5    Wilkerson, M.D.6
  • 5
    • 70849122697 scopus 로고    scopus 로고
    • Glioblastoma subclasses can be defined by activity among signal transduction pathways and associated genomic alterations
    • Brennan C, Momota H, Hambardzumyan D, Ozawa T, Tandon A, Pedraza A, et al. Glioblastoma subclasses can be defined by activity among signal transduction pathways and associated genomic alterations. PLoS One. 2009;4:e7752.
    • (2009) PLoS One. , vol.4
    • Brennan, C.1    Momota, H.2    Hambardzumyan, D.3    Ozawa, T.4    Tandon, A.5    Pedraza, A.6
  • 7
    • 79960809488 scopus 로고    scopus 로고
    • Mosaic analysis with double markers reveals tumor cell of origin in glioma
    • Liu C, Sage JC, Miller MR, Verhaak RG, Hippenmeyer S, Vogel H, et al. Mosaic analysis with double markers reveals tumor cell of origin in glioma. Cell. 2011;146:209-21.
    • (2011) Cell. , vol.146 , pp. 209-221
    • Liu, C.1    Sage, J.C.2    Miller, M.R.3    Verhaak, R.G.4    Hippenmeyer, S.5    Vogel, H.6
  • 8
    • 67349108288 scopus 로고    scopus 로고
    • Oligodendrocyte progenitor cells can act as cell of origin for experimental glioma
    • Lindberg N, Kastemar M, Olofsson T, Smits A, Uhrbom L. Oligodendrocyte progenitor cells can act as cell of origin for experimental glioma. Oncogene. 2009;28:2266-75.
    • (2009) Oncogene. , vol.28 , pp. 2266-2275
    • Lindberg, N.1    Kastemar, M.2    Olofsson, T.3    Smits, A.4    Uhrbom, L.5
  • 9
    • 0033040497 scopus 로고    scopus 로고
    • Subventricular zone astrocytes are neural stem cells in the adult mammalian brain
    • DOI 10.1016/S0092-8674(00)80783-7
    • Doetsch F, Caille I, Lim DA, Garcia-Verdugo JM, Alvarez-Buylla A. Subventricular zone astrocytes are neural stem cells in the adult mammalian brain. Cell. 1999;97:703-16. (Pubitemid 29278045)
    • (1999) Cell , vol.97 , Issue.6 , pp. 703-716
    • Doetsch, F.1    Caille, I.2    Lim, D.A.3    Garcia-Verdugo, J.M.4    Alvarez-Buylla, A.5
  • 10
    • 0026535505 scopus 로고
    • Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system
    • Reynolds BA, Weiss S. Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science. 1992;255:1707-10.
    • (1992) Science. , vol.255 , pp. 1707-1710
    • Reynolds, B.A.1    Weiss, S.2
  • 12
    • 0027405346 scopus 로고
    • Both oligodendrocytes and astrocytes develop from progenitors in the subventricular zone of postnatal rat forebrain
    • DOI 10.1016/0896-6273(93)90311-E
    • Levison SW, Goldman JE. Both oligodendrocytes and astro-cytes develop from progenitors in the subventricular zone of postnatal rat forebrain. Neuron. 1993;10:201-12. (Pubitemid 23079542)
    • (1993) Neuron , vol.10 , Issue.2 , pp. 201-212
    • Levison, S.W.1    Goldman, J.E.2
  • 16
    • 33845317573 scopus 로고    scopus 로고
    • Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
    • DOI 10.1038/nature05236, PII NATURE05236
    • Bao S, Wu Q, McLendon RE, Hao Y, Shi Q, Hjelmeland AB, et al. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature. 2006;444:756-60. (Pubitemid 44949604)
    • (2006) Nature , vol.444 , Issue.7120 , pp. 756-760
    • Bao, S.1    Wu, Q.2    McLendon, R.E.3    Hao, Y.4    Shi, Q.5    Hjelmeland, A.B.6    Dewhirst, M.W.7    Bigner, D.D.8    Rich, J.N.9
  • 17
    • 60849117508 scopus 로고    scopus 로고
    • PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells
    • Bleau AM, Hambardzumyan D, Ozawa T, Fomchenko EI, Huse JT, Brennan CW, et al. PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells. Cell Stem Cell. 2009;4:226-35.
    • (2009) Cell Stem Cell. , vol.4 , pp. 226-235
    • Bleau, A.M.1    Hambardzumyan, D.2    Ozawa, T.3    Fomchenko, E.I.4    Huse, J.T.5    Brennan, C.W.6
  • 19
    • 0034762880 scopus 로고    scopus 로고
    • Modeling gliomagenesis with somatic cell gene transfer using retroviral vectors
    • DOI 10.1023/A:1012208314436
    • Uhrbom L, Holland EC. Modeling gliomagenesis with somatic cell gene transfer using retroviral vectors. J Neurooncol. 2001;53:297-305. (Pubitemid 33034681)
    • (2001) Journal of Neuro-Oncology , vol.53 , Issue.3 , pp. 297-305
    • Uhrbom, L.1    Holland, E.C.2
  • 21
    • 0035425048 scopus 로고    scopus 로고
    • PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas from and oligoastrocytomas neural progenitors and astrocytes in vivo
    • DOI 10.1101/gad.903001
    • Dai C, Celestino JC, Okada Y, Louis DN, Fuller GN, Holland EC. PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oli-goastrocytomas from neural progenitors and astrocytes in vivo. Genes Dev. 2001;15:1913-25. (Pubitemid 32738621)
    • (2001) Genes and Development , vol.15 , Issue.15 , pp. 1913-1925
    • Dai, C.1    Celestino, J.C.2    Okada, Y.3    Louis, D.N.4    Fuller, G.N.5    Holland, E.C.6
  • 23
    • 34648834721 scopus 로고    scopus 로고
    • Loss of Arf causes tumor progression of PDGFB-induced oligodendroglioma
    • DOI 10.1038/sj.onc.1210455, PII 1210455
    • Tchougounova E, Kastemar M, Brasater D, Holland EC, Westermark B, Uhrbom L. Loss of Arf causes tumor progression of PDGFB-induced oligodendroglioma. Oncogene. 2007;26:6289-96. (Pubitemid 47462106)
    • (2007) Oncogene , vol.26 , Issue.43 , pp. 6289-6296
    • Tchougounova, E.1    Kastemar, M.2    Brasater, D.3    Holland, E.C.4    Westermark, B.5    Uhrbom, L.6
  • 25
    • 0014783392 scopus 로고
    • The proliferation of astrocytes around a needle wound in the rat brain
    • Cavanagh JB. The proliferation of astrocytes around a needle wound in the rat brain. J Anat. 1970;106:471-87.
    • (1970) J Anat. , vol.106 , pp. 471-487
    • Cavanagh, J.B.1
  • 26
    • 0019779882 scopus 로고
    • Anaplastic human gliomas grown in athymic mice. Morphology and glial fibrillary acidic protein expression
    • Jones TR, Bigner SH, Schold SC Jr, Eng LF, Bigner DD. Anaplastic human gliomas grown in athymic mice. Morphology and glial fibrillary acidic protein expression. Am J Pathol. 1981;105:316-27. (Pubitemid 12253493)
    • (1981) American Journal of Pathology , vol.105 , Issue.3 , pp. 316-327
    • Jones, T.R.1    Bigner, S.H.2    Schold Jr., S.C.3
  • 27
    • 34247500441 scopus 로고    scopus 로고
    • Transforming growth factor α promotes sequential conversion of mature astrocytes into neural progenitors and stem cells
    • DOI 10.1038/sj.onc.1210071, PII 1210071
    • Sharif A, Legendre P, Prevot V, Allet C, Romao L, Studler JM, et al. Transforming growth factor alpha promotes sequential conversion of mature astrocytes into neural progenitors and stem cells. Oncogene. 2007;26:2695-706. (Pubitemid 46663827)
    • (2007) Oncogene , vol.26 , Issue.19 , pp. 2695-2706
    • Sharif, A.1    Legendre, P.2    Prevot, V.3    Allet, C.4    Romao, L.5    Studler, J.-M.6    Chneiweiss, H.7    Junier, M.-P.8
  • 28
    • 70350216061 scopus 로고    scopus 로고
    • Astrocytes reverted to a neural progenitor-like state with transforming growth factor alpha are sensitized to cancerous transformation
    • Dufour C, Cadusseau J, Varlet P, Surena AL, de Faria GP, Dias-Morais A, et al. Astrocytes reverted to a neural progenitor-like state with transforming growth factor alpha are sensitized to cancerous transformation. Stem Cells. 2009; 27:2373-82.
    • (2009) Stem Cells. , vol.27 , pp. 2373-2382
    • Dufour, C.1    Cadusseau, J.2    Varlet, P.3    Surena, A.L.4    De Faria, G.P.5    Dias-Morais, A.6
  • 30
    • 0030927381 scopus 로고    scopus 로고
    • Development and malignant progression of astrocytomas in GFAP-v-src transgenic mice
    • Weissenberger J, Steinbach JP, Malin G, Spada S, Rulicke T, Aguzzi A. Development and malignant progression of astro-cytomas in GFAP-v-src transgenic mice. Oncogene. 1997;14: 2005-13. (Pubitemid 27237002)
    • (1997) Oncogene , vol.14 , Issue.17 , pp. 2005-2013
    • Weissenberger, J.1    Steinbach, J.P.2    Malin, G.3    Spada, S.4    Rulicke, T.5    Aguzzi, A.6
  • 31
    • 0035328722 scopus 로고    scopus 로고
    • Astrocyte-specific expression of activated p21-ras results in malignant astrocytoma formation in a transgenic mouse model of human gliomas
    • Ding H, Roncari L, Shannon P, Wu X, Lau N, Karaskova J, et al. Astrocyte-specific expression of activated p21-ras results in malignant astrocytoma formation in a trans-genic mouse model of human gliomas. Cancer Res. 2001;61: 3826-36. (Pubitemid 32695000)
    • (2001) Cancer Research , vol.61 , Issue.9 , pp. 3826-3836
    • Ding, H.1    Roncari, L.2    Shannon, P.3    Wu, X.4    Lau, N.5    Karaskova, J.6    Gutmann, D.H.7    Squire, J.A.8    Nagy, A.9    Guha, A.10
  • 32
    • 0036490954 scopus 로고    scopus 로고
    • Astrocyte inactivation of the pRb pathway predisposes mice to malignant astrocytoma development that is accelerated by PTEN mutation
    • DOI 10.1016/S1535-6108(02)00029-6
    • Xiao A, Wu H, Pandolfi PP, Louis DN, Van Dyke T. Astro-cyte inactivation of the pRb pathway predisposes mice to malignant astrocytoma development that is accelerated by PTEN mutation. Cancer Cell. 2002;1:157-68. (Pubitemid 41039162)
    • (2002) Cancer Cell , vol.1 , Issue.2 , pp. 157-168
    • Xiao, A.1    Wu, H.2    Pandolfi, P.P.3    Louis, D.N.4    Van Dyke, T.5
  • 33
    • 0036720309 scopus 로고    scopus 로고
    • Initial stages of radial glia astrocytic transformation in the early postnatal anterior subventricular zone
    • Alves JA, Barone P, Engelender S, Froes MM, Menezes JR. Initial stages of radial glia astrocytic transformation in the early postnatal anterior subventricular zone. J Neurobiol. 2002;52: 251-65.
    • (2002) J Neurobiol. , vol.52 , pp. 251-265
    • Alves, J.A.1    Barone, P.2    Engelender, S.3    Froes, M.M.4    Menezes, J.R.5
  • 35
    • 0002390849 scopus 로고
    • The subependymal cell plate (matrix) and its relation to brain tumors of ependymal type
    • Globus JH, Kuhlenbeck H. The subependymal cell plate (matrix) and its relation to brain tumors of ependymal type. J Neuropathol Exp Neurol. 1944;3:35.
    • (1944) J Neuropathol Exp Neurol. , vol.3 , pp. 35
    • Globus, J.H.1    Kuhlenbeck, H.2
  • 37
    • 0014597293 scopus 로고
    • The importance of implantation site in cerebral carcinogenesis in rats
    • Hopewell JW, Wright EA. The importance of implantation site in cerebral carcinogenesis in rats. Cancer Res. 1969;29: 1927-31.
    • (1969) Cancer Res. , vol.29 , pp. 1927-1931
    • Hopewell, J.W.1    Wright, E.A.2
  • 38
    • 0016530581 scopus 로고
    • The induction of intractranial neoplasms by the inoculation of avian sarcoma virus in perinatal and adult rats
    • Copeland DD, Vogel FS, Bigner DD. The induction of intractranial neoplasms by the inoculation of avian sarcoma virus in perinatal and adult rats. J Neuropathol Exp Neurol. 1975;34:340-58.
    • (1975) J Neuropathol Exp Neurol. , vol.34 , pp. 340-358
    • Copeland, D.D.1    Vogel, F.S.2    Bigner, D.D.3
  • 39
    • 0001623162 scopus 로고
    • Presence of DNA synthesis and mitosis in the brain of young adult mice
    • Messier B, Leblond CP, Smart I. Presence of DNA synthesis and mitosis in the brain of young adult mice. Exp Cell Res. 1958;14:224-6.
    • (1958) Exp Cell Res. , vol.14 , pp. 224-226
    • Messier, B.1    Leblond, C.P.2    Smart, I.3
  • 40
    • 0014407342 scopus 로고
    • Mitotic activity in the primate subependymal layer and the genesis of gliomas
    • Lewis PD. Mitotic activity in the primate subependymal layer and the genesis of gliomas. Nature. 1968;217:974-5.
    • (1968) Nature. , vol.217 , pp. 974-975
    • Lewis, P.D.1
  • 42
    • 0034044574 scopus 로고    scopus 로고
    • Sox2 regulatory sequences direct expression of a β-geo transgene to telencephalic neural stem cells and precursors of the mouse embryo, revealing regionalization of gene expression in CNS stem cells
    • Zappone MV, Galli R, Catena R, Meani N, De Biasi S, Mattei E, et al. Sox2 regulatory sequences direct expression of a (beta)-geo transgene to telencephalic neural stem cells and precursors of the mouse embryo, revealing regionalization of gene expression in CNS stem cells. Development. 2000;127: 2367-82. (Pubitemid 30386576)
    • (2000) Development , vol.127 , Issue.11 , pp. 2367-2382
    • Zappone, M.V.1    Galli, R.2    Catena, R.3    Meani, N.4    De Biasi, S.5    Mattei, E.6    Tiveron, C.7    Vescovi, A.L.8    Lovell-Badge, R.9    Ottolenghi, S.10    Nicolis, S.K.11
  • 44
    • 30444456264 scopus 로고    scopus 로고
    • Adult human subventricular, subgranular, and subpial zones contain astrocytes with a specialized intermediate filament cytoskeleton
    • DOI 10.1002/glia.20243
    • Roelofs RF, Fischer DF, Houtman SH, Sluijs JA, Van Haren W, Van Leeuwen FW, et al. Adult human sub-ventricular, subgranular, and subpial zones contain astrocytes with a specialized intermediate filament cytoskeleton. Glia. 2005;52:289-300. (Pubitemid 43076221)
    • (2005) GLIA , vol.52 , Issue.4 , pp. 289-300
    • Roelofs, R.F.1    Fischer, D.F.2    Houtman, S.H.3    Sluijs, J.A.4    Van Haren, W.5    Van Leeuwen, F.W.6    Hol, E.M.7
  • 45
    • 0024400631 scopus 로고
    • Epidermal growth factor immunoreactive material in the rat brain. Localization and identification of multiple species
    • Schaudies RP, Christian EL, Savage CR Jr. Epidermal growth factor immunoreactive material in the rat brain. Localization and identification of multiple species. J Biol Chem. 1989;264: 10447-50. (Pubitemid 19161607)
    • (1989) Journal of Biological Chemistry , vol.264 , Issue.18 , pp. 10447-10450
    • Schaudies, R.P.1    Chirstian, E.L.2    Savage Jr., C.R.3
  • 46
    • 0030809453 scopus 로고    scopus 로고
    • Epidermal growth factor and fibroblast growth factor-2 have different effects on neural progenitors in the adult rat brain
    • Kuhn HG, Winkler J, Kempermann G, Thal LJ, Gage FH. Epidermal growth factor and fibroblast growth factor-2 have different effects on neural progenitors in the adult rat brain. J Neurosci. 1997;17:5820-9. (Pubitemid 27310497)
    • (1997) Journal of Neuroscience , vol.17 , Issue.15 , pp. 5820-5829
    • Kuhn, H.G.1    Winkler, J.2    Kempermann, G.3    Thal, L.J.4    Gage, F.H.5
  • 47
    • 0025114687 scopus 로고
    • Identical splicing of aberrant epidermal growth factor receptor transcripts from amplified rearranged genes in human glioblasto-mas
    • Sugawa N, Ekstrand AJ, James CD, Collins VP. Identical splicing of aberrant epidermal growth factor receptor transcripts from amplified rearranged genes in human glioblasto-mas. Proc Natl Acad Sci USA. 1990;87:8602-6.
    • (1990) Proc Natl Acad Sci USA. , vol.87 , pp. 8602-8606
    • Sugawa, N.1    Ekstrand, A.J.2    James, C.D.3    Collins, V.P.4
  • 48
    • 0034163550 scopus 로고    scopus 로고
    • Diversity and frequency of epidermal growth factor receptor mutations in human glioblastomas
    • Frederick L, Wang XY, Eley G, James CD. Diversity and frequency of epidermal growth factor receptor mutations in human glioblastomas. Cancer Res. 2000;60:1383-7. (Pubitemid 30152011)
    • (2000) Cancer Research , vol.60 , Issue.5 , pp. 1383-1387
    • Frederick, L.1    Wang, X.-Y.2    Eley, G.3    James, C.D.4
  • 49
    • 67349137902 scopus 로고    scopus 로고
    • The EGFRvIII variant in glioblastoma multiforme
    • Gan HK, Kaye AH, Luwor RB. The EGFRvIII variant in glioblastoma multiforme. J Clin Neurosci. 2009;16:748-54.
    • (2009) J Clin Neurosci. , vol.16 , pp. 748-754
    • Gan, H.K.1    Kaye, A.H.2    Luwor, R.B.3
  • 50
    • 0035824396 scopus 로고    scopus 로고
    • Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo
    • DOI 10.1126/science.1065518
    • Groszer M, Erickson R, Scripture-Adams DD, Lesche R, Trumpp A, Zack JA, et al. Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo. Science. 2001;294:2186-9. (Pubitemid 33150679)
    • (2001) Science , vol.294 , Issue.5549 , pp. 2186-2189
    • Groszer, M.1    Erickson, R.2    Scripture-Adams, D.D.3    Lesche, R.4    Trumpp, A.5    Zack, J.A.6    Kornblum, H.I.7    Liu, X.8    Wu, H.9
  • 51
    • 0028201742 scopus 로고
    • Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene
    • van der Lugt NM, Domen J, Linders K, van Roon M, Robanus-Maandag E, te Riele H, et al. Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene. Genes Dev. 1994;8:757-69.
    • (1994) Genes Dev. , vol.8 , pp. 757-769
    • Van Der Lugt, N.M.1    Domen, J.2    Linders, K.3    Van Roon, M.4    Robanus-Maandag, E.5    Te Riele, H.6
  • 52
    • 0242667922 scopus 로고    scopus 로고
    • Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation
    • DOI 10.1038/nature02060
    • Molofsky AV, Pardal R, Iwashita T, Park IK, Clarke MF, Morrison SJ. Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation. Nature. 2003;425: 962-7. (Pubitemid 37376927)
    • (2003) Nature , vol.425 , Issue.6961 , pp. 962-967
    • Molofsky, A.V.1    Pardal, R.2    Iwashita, T.3    Park, I.-K.4    Clarke, M.F.5    Morrison, S.J.6
  • 54
    • 56449126945 scopus 로고    scopus 로고
    • Targeting of the Bmi-1 oncogene/stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-renewal
    • Godlewski J, Nowicki MO, Bronisz A, Williams S, Otsuki A, Nuovo G, et al. Targeting of the Bmi-1 oncogene/stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-renewal. Cancer Res. 2008;68:9125-30.
    • (2008) Cancer Res. , vol.68 , pp. 9125-9130
    • Godlewski, J.1    Nowicki, M.O.2    Bronisz, A.3    Williams, S.4    Otsuki, A.5    Nuovo, G.6
  • 55
    • 38049177209 scopus 로고    scopus 로고
    • Notch regulates cell fate and dendrite morphology of newborn neurons in the postnatal dentate gyrus
    • Breunig JJ, Silbereis J, Vaccarino FM, Sestan N, Rakic P. Notch regulates cell fate and dendrite morphology of newborn neurons in the postnatal dentate gyrus. Proc Natl Acad Sci USA. 2007;104:20558-63.
    • (2007) Proc Natl Acad Sci USA. , vol.104 , pp. 20558-20563
    • Breunig, J.J.1    Silbereis, J.2    Vaccarino, F.M.3    Sestan, N.4    Rakic, P.5
  • 56
  • 58
    • 0025188130 scopus 로고
    • The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain
    • McMahon AP, Bradley A. The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain. Cell. 1990;62:1073-85.
    • (1990) Cell. , vol.62 , pp. 1073-1085
    • McMahon, A.P.1    Bradley, A.2
  • 59
    • 79953014281 scopus 로고    scopus 로고
    • Wnt signaling regulates symmetry of division of neural stem cells in the adult brain and in response to injury
    • Piccin D, Morshead CM. Wnt signaling regulates symmetry of division of neural stem cells in the adult brain and in response to injury. Stem Cells. 2011;29:528-38.
    • (2011) Stem Cells. , vol.29 , pp. 528-538
    • Piccin, D.1    Morshead, C.M.2
  • 60
    • 79958171015 scopus 로고    scopus 로고
    • Wnt/beta-Catenin pathway in human glioma: Expression pattern and clinical/prognostic correlations
    • Liu C, Tu Y, Sun X, Jiang J, Jin X, Bo X, et al. Wnt/beta-Catenin pathway in human glioma: expression pattern and clinical/prognostic correlations. Clin Exp Med. 2011;11: 105-12.
    • (2011) Clin Exp Med. , vol.11 , pp. 105-112
    • Liu, C.1    Tu, Y.2    Sun, X.3    Jiang, J.4    Jin, X.5    Bo, X.6
  • 61
    • 23644443053 scopus 로고    scopus 로고
    • Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma
    • DOI 10.1016/j.ccr.2005.07.004, PII S153561080500228X
    • Zhu Y, Guignard F, Zhao D, Liu L, Burns DK, Mason RP, et al. Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocy-toma. Cancer Cell. 2005;8:119-30. (Pubitemid 41132741)
    • (2005) Cancer Cell , vol.8 , Issue.2 , pp. 119-130
    • Zhu, Y.1    Guignard, F.2    Zhao, D.3    Liu, L.4    Burns, D.K.5    Mason, R.P.6    Messing, A.7    Parada, L.F.8
  • 62
    • 44849089702 scopus 로고    scopus 로고
    • Pten haploinsufficiency accelerates formation of high-grade astrocytomas
    • Kwon CH, Zhao D, ChenJ, Alcantara S, Li Y, Burns DK, etal. Pten haploinsufficiency accelerates formation of high-grade astrocytomas. Cancer Res. 2008;68:3286-94.
    • (2008) Cancer Res. , vol.68 , pp. 3286-3294
    • Kwon, C.H.1    Zhao, D.2    Chenj Alcantara, S.3    Li, Y.4    Burns, D.K.5
  • 63
    • 57849109837 scopus 로고    scopus 로고
    • Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model
    • Alcantara Llaguno S, Chen J, Kwon CH, Jackson EL, Li Y, Burns DK, et al. Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model. Cancer Cell. 2009;15:45-56.
    • (2009) Cancer Cell. , vol.15 , pp. 45-56
    • Alcantara Llaguno, S.1    Chen, J.2    Kwon, C.H.3    Jackson, E.L.4    Li, Y.5    Burns, D.K.6
  • 64
    • 0034020459 scopus 로고    scopus 로고
    • Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice
    • DOI 10.1038/75596
    • Holland EC, Celestino J, Dai C, Schaefer L, Sawaya RE, Fuller GN. Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice. Nat Genet. 2000;25:55-7. (Pubitemid 30257036)
    • (2000) Nature Genetics , vol.25 , Issue.1 , pp. 55-57
    • Holland, E.C.1    Celestino, J.2    Dai, C.3    Schaefer, L.4    Sawaya, R.E.5    Fuller, G.N.6
  • 65
    • 34547095240 scopus 로고    scopus 로고
    • Spontaneous transformation of human adult nontumorigenic stem cells to cancer stem cells is driven by genomic instability in a human model of glioblastoma
    • DOI 10.1634/stemcells.2006-0585
    • Shiras A, Chettiar ST, Shepal V, Rajendran G, Prasad GR, Shastry P. Spontaneous transformation of human adult non-tumorigenic stem cells to cancer stem cells is driven by genomic instability in a human model of glioblastoma. Stem Cells. 2007;25:1478-89. (Pubitemid 47106016)
    • (2007) Stem Cells , vol.25 , Issue.6 , pp. 1478-1489
    • Shiras, A.1    Chettiar T, S.2    Shepal, V.3    Rajendran, G.4    Rajendra Prasad, G.5    Shastry, P.6
  • 66
    • 0142250835 scopus 로고    scopus 로고
    • NG2-expressing glial progenitor cells: An abundant and widespread population of cycling cells in the adult rat CNS
    • DOI 10.1016/S1044-7431(03)00210-0
    • Dawson MR, Polito A, Levine JM, Reynolds R. NG2-expres-sing glial progenitor cells: an abundant and widespread population of cycling cells in the adult rat CNS. Mol Cell Neurosci. 2003;24:476-88. (Pubitemid 37311310)
    • (2003) Molecular and Cellular Neuroscience , vol.24 , Issue.2 , pp. 476-488
    • Dawson, M.R.L.1    Polito, A.2    Levine, J.M.3    Reynolds, R.4
  • 67
    • 33746055320 scopus 로고    scopus 로고
    • Co-expression of PDGF α receptor and NG2 by oligodendrocyte precursors in human CNS and multiple sclerosis lesions
    • DOI 10.1016/j.jneuroim.2006.04.014, PII S0165572806001329
    • Wilson HC, Scolding NJ, Raine CS. Co-expression of PDGF alpha receptor and NG2 by oligodendrocyte precursors in human CNS and multiple sclerosis lesions. J Neuroimmunol. 2006;176:162-73. (Pubitemid 44080336)
    • (2006) Journal of Neuroimmunology , vol.176 , Issue.1-2 , pp. 162-173
    • Wilson, H.C.1    Scolding, N.J.2    Raine, C.S.3
  • 68
    • 34447512642 scopus 로고    scopus 로고
    • NG2-positive cells generate A2B5-positive oligodendrocyte precursor cells
    • DOI 10.1002/glia.20519
    • Baracskay KL, Kidd GJ, Miller RH, Trapp BD. NG2-positive cells generate A2B5-positive oligodendrocyte precursor cells. Glia. 2007;55:1001-10. (Pubitemid 47066740)
    • (2007) GLIA , vol.55 , Issue.10 , pp. 1001-1010
    • Baracskay, K.L.1    Kidd, G.J.2    Miller, R.H.3    Trapp, B.D.4
  • 69
    • 0028363067 scopus 로고
    • Differential regulation of the 2', 3'-cyclic nucleo-tide 3'-phosphodiesterase gene during oligodendrocyte development
    • Scherer SS, Braun PE, Grinspan J, Collarini E, Wang DY, Kamholz J. Differential regulation of the 2', 3'-cyclic nucleo-tide 3'-phosphodiesterase gene during oligodendrocyte development. Neuron. 1994;12:1363-75.
    • (1994) Neuron. , vol.12 , pp. 1363-1375
    • Scherer, S.S.1    Braun, P.E.2    Grinspan, J.3    Collarini, E.4    Wang, D.Y.5    Kamholz, J.6
  • 72
    • 0026542105 scopus 로고
    • In vitro analysis of the origin and maintenance of O-2Aadult progenitor cells
    • Wren D, Wolswijk G, Noble M. In vitro analysis of the origin and maintenance of O-2Aadult progenitor cells. J Cell Biol. 1992;116:167-76.
    • (1992) J Cell Biol. , vol.116 , pp. 167-176
    • Wren, D.1    Wolswijk, G.2    Noble, M.3
  • 73
    • 0034622930 scopus 로고    scopus 로고
    • Oligodendrocyte precursor cells repro-grammed to become multipotential CNS stem cells
    • Kondo T, Raff M. Oligodendrocyte precursor cells repro-grammed to become multipotential CNS stem cells. Science. 2000;289:1754-7.
    • (2000) Science. , vol.289 , pp. 1754-1757
    • Kondo, T.1    Raff, M.2
  • 74
    • 79953773786 scopus 로고    scopus 로고
    • Combination of a ptgs2 inhibitor and an epidermal growth factor receptor-signaling inhibitor prevents tumorigen-esis of oligodendrocyte lineage-derived glioma-initiating cells
    • Hide T, Takezaki T, Nakatani Y, Nakamura H, Kuratsu J, Kondo T. Combination of a ptgs2 inhibitor and an epidermal growth factor receptor-signaling inhibitor prevents tumorigen-esis of oligodendrocyte lineage-derived glioma-initiating cells. Stem Cells. 2011;29:590-9.
    • (2011) Stem Cells. , vol.29 , pp. 590-599
    • Hide, T.1    Takezaki, T.2    Nakatani, Y.3    Nakamura, H.4    Kuratsu, J.5    Kondo, T.6
  • 75
    • 16844370694 scopus 로고    scopus 로고
    • Cell type-specific tumor suppression by Ink4a and Arf in kras-induced mouse gliomagenesis
    • DOI 10.1158/0008-5472.CAN-04-3588
    • Uhrbom L, Kastemar M, Johansson FK, Westermark B, Holland EC. Cell type-specific tumor suppression by Ink4a and Arf in Kras-induced mouse gliomagenesis. Cancer Res. 2005;65:2065-9. (Pubitemid 40490109)
    • (2005) Cancer Research , vol.65 , Issue.6 , pp. 2065-2069
    • Uhrbom, L.1    Kastemar, M.2    Johansson, F.K.3    Westermark, B.4    Holland, E.C.5
  • 76
    • 79953281617 scopus 로고    scopus 로고
    • Mapping cancer origins
    • Gilbertson RJ. Mapping cancer origins. Cell. 2011;145:25-9.
    • (2011) Cell. , vol.145 , pp. 25-29
    • Gilbertson, R.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.