Preventive and curative effect of methanolic extract of Gardenia gummifera Linn. f. on thioacetamide induced oxidative stress in rats

Asian Pacific Journal of Tropical Disease

Volumn 2, Issue 2, 2012, Pages 90-98

  Prabha, S P ^a   Ansil, P N ^a   Nitha, A ^a   Wills, P J ^a   Latha, M S ^a  

^a MAHATMA GANDHI UNIVERSITY   (India)

Author keywords

Alanine aminotransferase; Antioxidant; Aspartate aminotransferase; Catalase; Gardenia gummifera; Glutathione peroxidase; Glutathione S transferase; Hepatoprotective; Oxidative stress; Silymarin; Thioacetamide

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; CATALASE; GARDENIA EXTRACT; GARDENIA GUMMIFERA EXTRACT; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; LACTATE DEHYDROGENASE; SILYMARIN; THIOACETAMIDE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; UNCLASSIFIED DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BLOOD SAMPLING; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFICACY; ENZYME INHIBITION; GARDENIA; GARDENIA GUMMIFERA; HISTOPATHOLOGY; LACTATE DEHYDROGENASE BLOOD LEVEL; LIPID PEROXIDATION; LIVER PROTECTION; LIVER TOXICITY; MALE; NONHUMAN; OXIDATIVE STRESS; PLANT ROOT; PRIORITY JOURNAL; RAT; TREATMENT RESPONSE;

EID: 84859900504     PISSN: 22221808     EISSN: None     Source Type: Journal    
DOI: 10.1016/S2222-1808(12)60023-1     Document Type: Article

References (35)

1. Chandrasekara A, Shahidi F Inhibitory activities of soluble and bound millet seed phenolics on free radicals and reactive oxygen species. J Agric Food Chem 2011, 59(1):428-436.
2. Rajkumar V, Guha G, Kumar RA, Mathew L Evaluation of antioxidant activities of Bergenia ciliata rhizome. Rec Nat Prod 2010, 4(1):38-48.
3. Khare CP Indian medicinal plants: An illustrated dictionary 2007, 45. Springer, New York.
4. Varier PS Indian medicinal plants-a compendium of 500 species 1995, 65-68. Orient Longman Publications, Madras.
5. Mir FA, Yadav AS, Wankhede S Efficiency of media's for propagation of medicinal tree Gardenia gummifera Linn.f.-An endangered medicinal plant. J Phytol 2010, 2(8):47-51.
6. Reddy GCS, Rangaswami S, Sunder R Triterpenoids of the stem bark of Gardenia gummifera. Planta Med 1977, 32(3):206-211.
7. Devaraj VC, Krishna BG, Viswanatha GL, Kamath JV, Kumar S Hepatoprotective activity of Hepax-A polyherbal formulation. Asian Pac J Trop Biomed 2011, 1:142-146.
8. Shyamal S, Latha PG, Suja SR, Shine VJ, Anuja GI, Sini S, et al. Hepatoprotective effect of three herbal extracts on aflatoxin B1-intoxicated rat liver. Singapore Med J 2010, 51(4):326-331.
9. Roy CK, Kamath JV, Asad M Hepatoprotective activity of Psidium guajava Linn. leaf extract. Indian J Exp Biol 2006, 44(4):305-311.
10. Ahmad A, Pillai KK, Najmi AK, Ahmad SJ, Pal SN, Balani DK Evaluation of hepatoprotective potential of jigrine post-treatment against thioacetamide induced hepatic damage. J Ethnopharmacol 2002, 79(1):35-41.
11. El-Demerdash FM, Yousef MI, Radwan FM Ameliorating effect of curcumin on sodium arsenite-induced oxidative damage and lipid peroxidation in different rat organs. Food Chem Toxicol 2009, 47(1):249-254.
12. Ajith TA, Hema U, Aswathy MS Zingiber officinale Roscoe prevents acetaminophen-induced acute hepatotoxicity by enhancing hepatic antioxidant status. Food Chem Toxicol 2007, 45(11):2267-2272.
13. Beutler E Red cell metabolism: A manual of biochemical methods 1984, Grune and Startton, New York. 3rd ed.
14. Habig WH, Pabst MJ, Jakoby WB Glutathione S-transferase. The first enzymatic step in mercapturic acid formation. J Biol Chem 1974, 249(22):7130-7139.
15. Ellman GL Tissue sulfhydryl groups. Arch Biochem Biophys 1959, 82(1):70-77.
16. Hwang YP, Choi JH, Jeong HG Protective effect of the Aralia continentalis root extract against carbon tetrachloride-induced hepatotoxicity in mice. Food Chem Toxicol 2009, 47(1):75-81.
17. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ Protein measurements with the folin phenol reagent. J Biol Chem 1951, 193(1):265-275.
18. Wills PJ, Asha VV Protective effect of Lygodium flexuosum (L.) Sw. extract against carbon tetrachloride-induced acute liver injury in rats. J Ethnopharmacol 2006, 108(3):320-326.
19. Shapiro H, Ashkenazi M, Weizman N, Shahmurov M, Aeed H, Bruck R Curcumin ameliorates acute thioacetamide-induced hepatotoxicity. J Gastroenterol Hepatol 2006, 21(2):358-366.
20. Gupta NK, Dixit VK Hepatoprotective activity of Cleome viscosa Linn. extract against thioacetamide-induced hepatotoxicity in rats. Nat Prod Res 2009, 23(14):1289-1297.
21. Aydin AF, Kusku-Kiraz Z, Dogru-Abbasoglu S, Gulluoglu M, Uysal M, Kocak-Toker N Effect of carnosine against thioacetamide-induced liver cirrhosis in rat. Peptides 2010, 31(1):67-71.
22. 4-induced hepatic damage in rats. Sci Pharm 2008, 76(2):203-215.
23. Vadivu R, Krithika A, Biplab C, Dedeepya P, Shoeb N, Lakshmi KS Evaluation of hepatoprotective activity of the fruits of Coccinia grandis Linn. Int J Health Res 2008, 1:163-168.
24. Guerra RR, Trotta MR, Parra OM, Avanzo JL, Buteman A, Aloia TP, et al. Modulation of extracellular matrix by nutritional hepatotrophic factors in thioacetamide-induced liver cirrhosis in the rat. Braz J Med Biol Res 2009, 42(11):1027-1034.
25. Rosa MP, Gutierrez, Rosario VS Hepatoprotective and inhibition of oxidative stress of Prostechea michuacana. Rec Nat Prod 2009, 3(1):46-51.
26. Agarwal R, MacMillan-Crow LA, Rafferty TM, Sabu H, Roberts DM, Fifer EK, et al. Acetaminophen induced hepatotoxicity in mice occurs with inhibition of activity and nitration of mitochondrial manganese superoxide dismutase. J Pharmacol Exp Ther 2011, 337(1):110-116.
27. Okafor OY, Erukainure OL, Ajiboye JA, Adejobi RO, Owolabi FO, Kosoko SB Modulatory effect of pineapple peel extract on lipid peroxidation, catalase activity and hepatic biomarker levels in blood plasma of alcohol induced oxidative stressed rats. Asian Pac J Trop Biomed 2011, 1(1):12-14.
28. Erukainure OL, Ajiboye JA, Adejobi RO, Okafor OY, Adenekan SO Protective effect of pineapple (Ananas cosmosus) peel extract on alcohol-induced oxidative stress in brain tissues of male albino rats. Asian Pac J Trop Dis 2011, 1(1):5-9.
29. Jakoby WB Detoxification, conjugation and hydrolysis. Liver biology and pathology 1988, 375-385. Raven Press, New York. I.M. Arias, W.B. Jakoby (Eds.).
30. Carlberg I, Mannervik B Glutathione reductase. Methods Enzymol 1985, 113:484-490.
31. Ansil PN, Nitha A, Prabha SP, Wills PJ, Jazaira V, Latha MS Protective effect of Amorphophallus campanulatus (Roxb.) Blume. tuber against thioacetamide induced oxidative stress in rats. Asian Pac J Trop Med 2011, 4(11):870-877.
32. Ramanathan K, Balakumar BS, Panneerselvam C Effects of ascorbic acid and tocopherol on arsenic-induced oxidative stress. Hum Exp toxicol 2002, 21(12):675-680.
33. Freeman BA, Crapo JD Hyperoxia increases oxygen radical production in rat lung and lung mitochondria. J Biol Chem 1981, 256(21):10986-10992.
34. Tambekar DH, Khante BS, Chandak BR, Tltare AS, Boralkar SS, Aghadte SN Screening of antibacterial potentials of some medicinal plants from Melghat forest in India. Afr J Tradit Complement Altern Med 2009, 6(3):228-232.
35. Al-Qarawi AA, Mousa HM, Hamed Ali BE, Abdel-Rahman H, El-Mougy SA Protective effect of extracts from dates (Phoenix dactylifera L.) on carbon tetrachloride-induced hepatotoxicity in rats. Int J Appl Res Vet Med 2004, 2(3):176-180.