An increase in spinal cord noradrenaline is a major contributor to the antihyperalgesic effect of antidepressants after peripheral nerve injury in the rat

Pain

Volumn 153, Issue 5, 2012, Pages 990-997

  Nakajima, Kunie ^a   Obata, Hideaki ^a   Iriuchijima, Nobuhisa ^a   Saito, Shigeru ^a  

^a GUNMA UNIVERSITY   (Japan)

Author keywords

Antidepressants; Neuropathic pain; Noradrenaline; Spinal cord

Indexed keywords

IDAZOXAN; MAPROTILINE; MILNACIPRAN; NORADRENALIN; ONDANSETRON; PAROXETINE; SEROTONIN;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; MALE; MICRODIALYSIS; NEUROPATHIC PAIN; NONHUMAN; PERIPHERAL NERVE INJURY; PRIORITY JOURNAL; RAT; SPINAL CORD; SPINAL CORD DORSAL HORN; TREATMENT OUTCOME;

ADRENERGIC ALPHA-2 RECEPTOR ANTAGONISTS; ANALGESICS; ANIMALS; ANTIDEPRESSIVE AGENTS; CYCLOPROPANES; HYPERALGESIA; IDAZOXAN; MALE; NOREPINEPHRINE; PAIN MEASUREMENT; PERIPHERAL NERVE INJURIES; RATS; RATS, SPRAGUE-DAWLEY; SPINAL CORD; SPINAL NERVES;

EID: 84859886175     PISSN: 03043959     EISSN: 18726623     Source Type: Journal    
DOI: 10.1016/j.pain.2012.01.029     Document Type: Article

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