Combined effect of GSTT1 and GSTM1 polymorphisms on human male infertility in North Indian population

Reproductive Sciences

Volumn 19, Issue 3, 2012, Pages 312-316

  Jaiswal, Deepika ^a   Sah, Ravindra ^b   Agrawal, Neeraj K ^c   Dwivedi, U S ^c   Trivedi, Sameer ^c   Singh, Kiran ^a  

^a BANARAS HINDU UNIVERSITY   (India)

^b Sah Speciality Clinic   (India)

^c BANARAS HINDU UNIVERSITY   (India)

Author keywords

detoxification; GST; infertility; ROS; spermatogenesis

Indexed keywords

GENOMIC DNA; GLUTATHIONE TRANSFERASE M1; GLUTATHIONE TRANSFERASE T1; REACTIVE OXYGEN METABOLITE;

ADULT; ARTICLE; AZOOSPERMIA; CASE CONTROL STUDY; CONTROLLED STUDY; DNA FRAGMENTATION; DNA POLYMORPHISM; GENE DELETION; GENE FREQUENCY; GENE INTERACTION; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; INDIA; MAJOR CLINICAL STUDY; MALE; MALE FERTILITY; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

ADULT; CASE-CONTROL STUDIES; GENETIC ASSOCIATION STUDIES; GLUTATHIONE TRANSFERASE; HUMANS; INDIA; INFERTILITY, MALE; MALE; POLYMORPHISM, GENETIC;

EID: 84859857920     PISSN: 19337191     EISSN: 19337205     Source Type: Journal    
DOI: 10.1177/1933719111424451     Document Type: Article

References (33)

1. Matzuk MM, Lamb DJ. The biology of infertility: research advances and clinical challenges. Nat Med. 2008;14(11): 1197-1213.
2. Matzuk MM, Lamb DJ. Genetic dissection of mammalian fertility pathways. Nat cell Biol. 2002; (suppl 4):S41-S49. (Pubitemid 35175933)
3. McLachlan RI, Bryan MK. State of the art for genetic testing of infertile men. J Clin Endocrinol Metab. 2010;95(3):1013-1024.
4. Nachtigall RD. International disparities in access to infertility services. Fertil Steril. 2006;85(4):871-875.
5. Merzenich H, Zeeb H, Blettner M. Decreasing sperm quality: a global problem? BMC Public Health. 2010;10:24.
6. Lewis SEM, Aitken RJ. DNA damage to spermatozoa has impacts on fertilization and pregnancy. Cell Tissue Res. 2005;322(1): 33-41. (Pubitemid 41677654)
7. Shamsi MB, Venkatesh S, Kumar R, et al. Antioxidant levels in blood and seminal plasma and their impact on sperm parameters in infertile men. Indian J Biochem Biophys. 2010; 47(1):38-43.
8. Finotti AC, Costa E Silva RC, Bordin BM, Silva CT, Moura KK. Glutathione S-transferase M1 and T1 polymorphism in men with idiopathic infertility. Genet Mol Res. 2009;8(3): 1093-1098.
9. Rubes J, Selevan SG, Sram RJ, Evenson DP, Perreault SD. GSTM1 genotype influences the susceptibility of men to sperm DNA damage associated with exposure to air pollution. Mutat Res. 2007;625(1-2):20-28. (Pubitemid 350019471)
10. Babu KA, Rao KL, Kanakavalli M K, Suryanarayana VV, Deenadayal M, Singh L. CYP1A1, GSTM1 and GSTT1 genetic polymorphism is associated with susceptibility to polycystic ovaries in South Indian women. Reprod Biomed Online. 2004;9(2):194-200. (Pubitemid 39157482)
11. Ding Y, Chen ZF, Lin RY, et al. Relationship between endometriosis and glutathione S-transferase M1, T1 genes of the Uygurs and Hans in Xinjiang [in Chinese]. Zhonghua Fu Chan Ke Za Zhi. 2004;39(2):101-104.
12. Sergentanis TN, Economopoulos KP. GSTT1 and GSTP1 polymorphisms and breast cancer risk: a meta-analysis. Breast Cancer Res Treat. 2009;121(1):195-202.
13. Gopalakrishnan B, Shaha C. Inhibition of sperm glutathione Stransferase leads to functional impairment due to membrane damage. FEBS Lett 1998;422(3):296-300. (Pubitemid 28075482)
14. Strange RC, Spiteri MA, Ramachandran S, Fryer AA. Glutathione- Stransferase family of enzymes. Mutat Res. 2001; 482(1-2):21-26.
15. Pemble S, Schroeder KR, Spencer SR, et al. Human glutathione S-transferase Theta (GSTT1): cDNA cloning and the characterization of a genetic polymorphism. Biochem J. 1994;300(pt 1): 271-276. (Pubitemid 24151046)
16. Castellon EA. Influence of age, hormones and germ cells on glutathione S-transferase activity in cultured Sertoli cells. Int J Androl. 1999;22(1):49-55. (Pubitemid 29056017)
17. Zamudio NM, Chong S, O'Bryan MK. Epigenetic regulation in male germ cells. Reproduction. 2008;136(2):131-146.
18. Zhong S, Wyllie AH, Barnes D, Wolf CR, Spurr NK. Relationship between the GSTM1 genetic polymorphism and susceptibility to bladder, breast and colon cancer. Carcinogenesis 1993;14(9): 1821-1824. (Pubitemid 23290894)
19. Katoh T, Nagata N, Kuroda Y, et al. Glutathione S-transferase M1 (GSTM1), and T1 (GSTT1) genetic polymorphism and susceptibility to gastric and colorectal adenocarcinoma. Carcinogenesis. 1996;17(9):1855-1859. (Pubitemid 26325375)
20. Erdfelder E, Faul F, Buchner A. G*POWER: A general power analysis program. Behav Res Meth Instrum Comput. 1996;28: 1-11.
21. Mann CL, Davies MB, Boggild MD, et al. Glutathione S-transferase polymorphisms in MS: their relationship to disability. Neurology 2000;54(3):552-557. (Pubitemid 30082917)
22. Pasqualotto FF, Sharma RK, Nelson DR, Thomas AJ, Agarwal A. Relationship between oxidative stress, semen characteristics and clinical diagnosis in men undergoing infertility investigation. Fertil Steril. 2000;73(3):459-464. (Pubitemid 30109638)
23. Agarwal A, Said TM. Oxidative stress, DNA damage and apoptosis in male infertility: a clinical approach. BJU Int. 2005;95(4): 503-507. (Pubitemid 40311459)
24. Polonikov AV, Yarosh SL, Kokhtenko EV, Starodubova NI, Pakhomov SP, Orlova VS. The functional genotype of glutathione S-transferase T1 gene is strongly associated with increased risk of idiopathic infertility in Russian men. Fertil Steril. 2010;94(3): 1144-1147.
25. Wu QF, Xing JP, Tang KF, et al. Genetic polymorphism of glutathione S-transferase T1 gene and susceptibility to idiopathic azoospermia or oligospermia in northwestern China. Asian J Androl 2008;10(2):266-270.
26. Safarinejad MR, Shafiei N, Safarinejad S. The association of glutathione-S-transferase gene polymorphisms (GSTM1, GSTT1, GSTP1) with idiopathic male infertility. J Hum Genet. 2010; 55(9):565-570.
27. Dordevic V, Nikolic A, LjujicM, et al. Combined effect of GSTM1 gene deletion, GSTT1 gene deletion and MTHFR C677T mutation in male infertility. Arch Biol Sci. 2010;62(3):525-530.
28. Dhillon VS, Shahid M, Husain SA. Associations of MTHFR DNMT3b 4977 bp deletion in mtDNA and GSTM1 deletion, and aberrant CpG island hypermethylation of GSTM1 in nonobstructive infertility in Indian men. Mol Hum Reprod. 2007; 13(4):213-222. (Pubitemid 46554738)
29. Vani GT, Mukesh N, Siva Prasad B, et al. Role of glutathione S-transferase Mu-1 (GSTM1) polymorphism in oligospermic infertile males. Andrologia. 2009;42(4):213-217.
30. Khazamipour N, Noruzinia M, Fatehmanesh P, Keyhanee M, Pujol P. MTHFR promoter hypermethylation in testicular biopsies of patients with non-obstructive azoospermia: the role of epigenetics in male infertility. Hum Reprod. 2009;24(9):2361-2364.
31. Singh K, Singh SK, Sah R, Singh I, Raman R. Mutation C677T in the methylenetetrahydrofolate reductase gene is associated with male infertility in an Indian population. Int J Androl. 2005; 28(2):115-119. (Pubitemid 40461182)
32. Paracchini V, Garte S, Taioli E. MTHFR, C677T polymorphism, GSTM1 deletion and male infertility: a possible suggestion of a gene-gene interaction? Biomarkers. 2006;11(1):53-60. (Pubitemid 43250551)
33. Economopoulos KP, Sergentanis TN, Choussein S., Glutathione- S-transferase gene (GSTM1, GSTT1 and GSTP1) and idiopathic male infertility: novel perspectives versus facts. J Hum Genet. 2010;55(9):557-558.