Neuropsychological tools in hepatology: A survival guide for the clinician

Journal of Viral Hepatitis

Volumn 19, Issue 5, 2012, Pages 307-315

  Montagnese, S ^a   Schiff, S ^a,b   De Rui, M ^a   Crossey, M M E ^c   Amodio, P ^a   Taylor Robinson, Simon D ^c  

^a UNIVERSITY OF PADOVA   (Italy)

^b IRCCS SAN CAMILLO HOSPITAL   (Italy)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Cirrhosis; Hepatic encephalopathy; Hepatitis C infection; Neuropsychology

Indexed keywords

ATTENTION DISTURBANCE; CLINICAL DECISION MAKING; CLINICAL PRACTICE; COGNITION; COGNITIVE DEFECT; CONCENTRATION LOSS; DEMENTIA; DIAGNOSTIC TEST; DISEASE SEVERITY; END STAGE LIVER DISEASE; HEPATIC ENCEPHALOPATHY; HEPATITIS C; HUMAN; LIVER CIRRHOSIS; LIVER FAILURE; LIVER TRANSPLANTATION; NEUROPSYCHOLOGICAL TEST; PATIENT IDENTIFICATION; PRACTICE GUIDELINE; PRIORITY JOURNAL; REVIEW; SURVIVAL RATE;

GASTROENTEROLOGY; HEPATIC ENCEPHALOPATHY; HEPATITIS C, CHRONIC; HUMANS; LIVER FAILURE; LIVER TRANSPLANTATION; NEUROPSYCHOLOGICAL TESTS;

EID: 84859823826     PISSN: 13520504     EISSN: 13652893     Source Type: Journal    
DOI: 10.1111/j.1365-2893.2012.01592.x     Document Type: Review

References (52)

1. Rikkers L, Jenko P, Rudman D, Freides D. Subclinical hepatic encephalopathy: detection, prevalence, and relationship to nitrogen metabolism. Gastroenterology 1978; 75: 462-469. (Pubitemid 9003354)
2. Parsons-Smith BG, Summerskill WH, Dawson AM, Sherlock S. The electroencephalograph in liver disease. Lancet 1957; 273: 867-871.
3. Sherlock S, Summerskill WH, White LP, Phear EA. Portal-systemic encephalopathy; neurological complications of liver disease. Lancet 1954; 267: 454-457.
4. Conn HO, Leevy CM, Vlahcevic ZR et al. Comparison of lactulose and neomycin in the treatment of chronic portal-systemic encephalopathy. A double blind controlled trial. Gastroenterology 1977; 72: 573-583. (Pubitemid 8097592)
5. Forton DM, Allsop JM, Cox IJ et al. A review of cognitive impairment and cerebral metabolite abnormalities in patients with hepatitis C infection. AIDS 2005; 19(Suppl. 3): S53-S63. (Pubitemid 41682170)
6. Lezak MD. Neuropsychological Assessment, 3rd edn. New York: Oxford University Press, 1995.
7. Nithianantharajah J, Hannan AJ. The neurobiology of brain and cognitive reserve: mental and physical activity as modulators of brain disorders. Prog Neurobiol 2009; 89: 369-382.
8. Mann DT, Williams AM, Ward P, Janelle CM. Perceptual-cognitive expertise in sport: a meta-analysis. J Sport Exerc Psychol 2007; 29: 457-478.
9. Montagnese S, Cona G, Schiff S et al. The hunter and the pianist: two hepatic encephalopathy tales. J Clin Gastroenterol 2011; 45: 563-566.
10. Srivastava A, Mehta R, Rothke SP, Rademaker AW, Blei AT. Fitness to drive in patients with cirrhosis and portal-systemic shunting: a pilot study evaluating driving performance. J Hepatol 1994; 21: 1023-1028.
11. Montagnese S, Amodio P, Morgan MY. Methods for diagnosing hepatic encephalopathy in patients with cirrhosis: a multidimensional approach. Metab Brain Dis 2004; 19: 281-312. (Pubitemid 39361189)
12. Ferenci P, Lockwood A, Mullen K, Tarter R, Weissenborn K, Blei AT. Hepatic encephalopathy - definition, nomenclature, diagnosis, and quantification: final report of the working party at the 11th World Congresses of Gastroenterology, Vienna, 1998. Hepatology 2002; 35: 716-721. (Pubitemid 34183979)
13. Amodio P, Montagnese S, Gatta A, Morgan MY. Characteristics of minimal hepatic encephalopathy. Metab Brain Dis 2004; 19: 253-267. (Pubitemid 39361187)
14. Montagnese S, Biancardi A, Schiff S et al. Different biochemical correlates for different neuropsychiatric abnormalities in patients with cirrhosis. Hepatology 2011; 53: 558-566.
15. Wein C, Koch H, Popp B, Oehler G, Schauder P. Minimal hepatic encephalopathy impairs fitness to drive. Hepatology 2004; 39: 739-745. (Pubitemid 38337653)
16. Bajaj JS, Saeian K, Schubert CM et al. Minimal hepatic encephalopathy is associated with motor vehicle crashes: the reality beyond the driving test. Hepatology 2009; 50: 1175-1183.
17. Groeneweg M, Quero JC, De BI et al. Subclinical hepatic encephalopathy impairs daily functioning. Hepatology 1998; 28: 45-49. (Pubitemid 28299984)
18. Blei AT, Cordoba J. Subclinical encephalopathy. Dig Dis 1996; 14(Suppl. 1): 2-11.
19. Mapelli D, Iannizzi P, Biancardi A et al. Neuropsychological dysfunction in minimal hepatic encephalopathy: a review compared with own experience. In: Haussinger D, Kircheis G, Schliess F, eds. Hepatic Encephalopathy and Nitrogen Metabolism. Dordrecht, The Netherlands: Springer, 2006: 467-473.
20. Weissenborn K, Giewekemeyer K, Heidenreich S, Bokemeyer M, Berding G, Ahl B. Attention, memory, and cognitive function in hepatic encephalopathy. Metab Brain Dis 2005; 20: 359-367. (Pubitemid 43029808)
21. Bersagliere A, Raduazzo ID, Nardi M et al. Induced hyperammonaemia may compromise the ability to generate restful sleep in patients with cirrhosis. Hepatology 2012; 55: 869-878.
22. Montagnese S, Jackson C, Morgan MY. Spatio-temporal decomposition of the electroencephalogram in patients with cirrhosis. J Hepatol 2007; 46: 447-458. (Pubitemid 46185704)
23. Amodio P, Schiff S, Del PF, Mapelli D, Gatta A, Umilta C. Attention dysfunction in cirrhotic patients: an inquiry on the role of executive control, attention orienting and focusing. Metab Brain Dis 2005; 20: 115-127. (Pubitemid 40768488)
24. Amodio P, Marchetti P, Del Piccolo F et al. Visual attention in cirrhotic patients: a study on covert visual attention orienting. Hepatology 1998; 27: 1517-1523. (Pubitemid 28264673)
25. Schiff S, Vallesi A, Mapelli D et al. Impairment of response inhibition precedes motor alteration in the early stage of liver cirrhosis: a behavioral and electrophysiological study. Metab Brain Dis 2005; 20: 381-392. (Pubitemid 43029810)
26. Weissenborn K, Scholz M, Hinrichs H, Wiltfang J, Schmidt FW, Kunkel H. Neurophysiological assessment of early hepatic encephalopathy. Electroencephalogr Clin Neurophysiol 1990; 75: 289-295. (Pubitemid 20111466)
27. Schomerus H, Hamster W, Blunck H, Reinhard U, Mayer K, Dolle W. Latent portasystemic encephalopathy. I. Nature of cerebral functional defects and their effect on fitness to drive. Dig Dis Sci 1981; 26: 622-630. (Pubitemid 11093388)
28. Amodio P, Del Piccolo F, Marchetti P et al. Clinical features and survivial of cirrhotic patients with subclinical cognitive alterations detected by the number connection test and computerized psychometric tests. Hepatology 1999; 29: 1662-1667. (Pubitemid 29247036)
29. Bajaj JS, Saeian K, Verber MD et al. Inhibitory control test is a simple method to diagnose minimal hepatic encephalopathy and predict development of overt hepatic encephalopathy. Am J Gastroenterol 2007; 102: 754-760. (Pubitemid 46496606)
30. Amodio P, Ridola L, Schiff S et al. Improving the inhibitory control task to detect minimal hepatic encephalopathy. Gastroenterology 2010; 139: 510-518, 518.
31. Amodio P, Marchetti P, Del Piccolo F et al. Study on the Sternberg paradigm in cirrhotic patients without overt hepatic encephalopathy. Metab Brain Dis 1998; 13: 159-172. (Pubitemid 28350750)
32. Weissenborn K, Ennen JC, Schomerus H, Ruckert N, Hecker H. Neuropsychological characterization of hepatic encephalopathy. J Hepatol 2001; 34: 768-773. (Pubitemid 32488796)
33. Schomerus H, Hamster W. Neuropsychological aspects of portal-systemic encephalopathy. Metab Brain Dis 1998; 13: 361-377. (Pubitemid 29063735)
34. Gitlin N, Lewis DC, Hinkley L. The diagnosis and prevalence of subclinical hepatic encephalopathy in apparently healthy, ambulant, non-shunted patients with cirrhosis. J Hepatol 1986; 3: 75-82. (Pubitemid 16052757)
35. Randolph C, Hilsabeck R, Kato A et al. Neuropsychological assessment of hepatic encephalopathy: ISHEN practice guidelines. Liver Int 2009; 29: 629-635.
36. Guerit JM, Amantini A, Fischer C et al. Neurophysiological investigations of hepatic encephalopathy: ISHEN practice guidelines. Liver Int 2009; 29: 789-796.
37. Randolph C, Tierney MC, Mohr E, Chase TN. The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS): preliminary clinical validity. J Clin Exp Neuropsychol 1998; 20: 310-319. (Pubitemid 28539551)
38. Sotil EU, Gottstein J, Ayala E, Randolph C, Blei AT. Impact of preoperative overt hepatic encephalopathy on neurocognitive function after liver transplantation. Liver Transpl 2009; 15: 184-192.
39. Mardini H, Saxby BK, Record CO. Computerized psychometric testing in minimal encephalopathy and modulation by nitrogen challenge and liver transplant. Gastroenterology 2008; 135: 1582-1590.
40. Amodio P, Biancardi A, Montagnese S et al. Neurological complications after orthotopic liver transplantation. Dig Liver Dis 2007; 39: 740-747. (Pubitemid 47046640)
41. Forton DM, Taylor-Robinson SD, Thomas HC. Cerebral dysfunction in chronic hepatitis C infection. J Viral Hepat 2003; 10: 81-86. (Pubitemid 36359844)
42. Stasi C, Zignego AL, Laffi G, Rosselli M. The liver-cytokine-brain circuit in interferon-based treatment of patients with chronic viral hepatitis. J Viral Hepat 2011; 18: 525-532.
43. Forton DM, Allsop JM, Main J, Foster GR, Thomas HC, Taylor-Robinson SD. Evidence for a cerebral effect of the hepatitis C virus. Lancet 2001; 358: 38-39. (Pubitemid 32709741)
44. Forton DM, Thomas HC, Murphy CA et al. Hepatitis C and cognitive impairment in a cohort of patients with mild liver disease. Hepatology 2002; 35: 433-439. (Pubitemid 34106386)
45. Hilsabeck RC, Perry W, Hassanein TI. Neuropsychological impairment in patients with chronic hepatitis C. Hepatology 2002; 35: 440-446. (Pubitemid 34106387)
46. Hilsabeck RC, Hassanein TI, Carlson MD, Ziegler EA, Perry W. Cognitive functioning and psychiatric symptomatology in patients with chronic hepatitis C. J Int Neuropsychol Soc 2003; 9: 847-854. (Pubitemid 37139014)
47. Weissenborn K, Krause J, Bokemeyer M et al. Hepatitis C virus infection affects the brain-evidence from psychometric studies and magnetic resonance spectroscopy. J Hepatol 2004; 41: 845-851. (Pubitemid 39434316)
48. McAndrews MP, Farcnik K, Carlen P et al. Prevalence and significance of neurocognitive dysfunction in hepatitis C in the absence of correlated risk factors. Hepatology 2005; 41: 801-808. (Pubitemid 40462942)
49. Fontana RJ, Bieliauskas LA, Back-Madruga C et al. Cognitive function in hepatitis C patients with advanced fibrosis enrolled in the HALT-C trial. J Hepatol 2005; 43: 614-622. (Pubitemid 41253228)
50. Lowry D, Coughlan B, McCarthy O, Crowe J. Investigating health-related quality of life, mood and neuropsychological test performance in a homogeneous cohort of Irish female hepatitis C patients. J Viral Hepat 2010; 17: 352-359.
51. Cordoba J, Flavia M, Jacas C et al. Quality of life and cognitive function in hepatitis C at different stages of liver disease. J Hepatol 2003; 39: 231-238. (Pubitemid 36920559)
52. Soogoor M, Lynn HS, Donfield SM, Gomperts E, Bell TS, Daar ES. Hepatitis C virus infection and neurocognitive function. Neurology 2006; 67: 1482-1485. (Pubitemid 44632081)