Association of pericardial fat and coronary high-risk lesions as determined by cardiac CT

Atherosclerosis

Volumn 222, Issue 1, 2012, Pages 129-134

  Schlett, Christopher L ^a   Ferencik, Maros ^a   Kriegel, Matthias F ^a   Bamberg, Fabian ^b   Ghoshhajra, Brian B ^a   Joshi, Subodh B ^a   Nagurney, John T ^a   Fox, Caroline S ^c,d   Truong, Quynh A ^a   Hoffmann, Udo ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^c FRAMINGHAM HEART STUDY   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Adipose tissue; Cardiac CT angiography; Coronary artery disease; High risk lesions; Peri cardial fat; Vulnerable plaque

Indexed keywords

ADIPOSE TISSUE; ADULT; ARTICLE; BODY MASS; CARDIOVASCULAR RISK; COMPUTED TOMOGRAPHIC ANGIOGRAPHY; CONTROLLED STUDY; CORONARY ARTERY CALCIFICATION; CORONARY ARTERY DISEASE; CROSS-SECTIONAL STUDY; DISEASE ASSOCIATION; FEMALE; HIGH RISK PATIENT; HUMAN; HYPERCHOLESTEROLEMIA; MAJOR CLINICAL STUDY; MALE; OBSERVATIONAL STUDY; PERICARDIAL ADIPOSE TISSUE; PERICARDIUM; PRIORITY JOURNAL; RISK ASSESSMENT; THORAX PAIN;

ADIPOSE TISSUE; CORONARY ARTERY DISEASE; FEMALE; HUMANS; MALE; MIDDLE AGED; PERICARDIUM; RISK; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84859820005     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2012.02.029     Document Type: Article

References (42)

1. Nichols J.H., Samy B., Nasir K., et al. Volumetric measurement of pericardial adipose tissue from contrast-enhanced coronary computed tomography angiography: a reproducibility study. Journal of Cardiovascular Computed Tomography 2008, 2:288-295.
2. Rosito G.A., Massaro J.M., Hoffmann U., et al. Pericardial fat, visceral abdominal fat, cardiovascular disease risk factors, and vascular calcification in a community-based sample: the Framingham Heart Study. Circulation 2008, 117:605-613.
3. Wang C.P., Hsu H.L., Hung W.C., et al. Increased epicardial adipose tissue volume in type 2 diabetes mellitus and association with metabolic syndrome and severity of coronary atherosclerosis. Clinical Endocrinology 2008.
4. Iacobellis G., Barbaro G. The double role of epicardial adipose tissue as pro- and anti-inflammatory organ, Hormone and metabolic research=Hormon- und Stoffwechselforschung=Hormones et metabolisme 2008, 40:442-445.
5. Mazurek T., Zhang L., Zalewski A., et al. Human epicardial adipose tissue is a source of inflammatory mediators. Circulation 2003, 108:2460-2466.
6. Baker A.R., Silva N.F., Quinn D.W., et al. Human epicardial adipose tissue expresses a pathogenic profile of adipocytokines in patients with cardiovascular disease. Cardiovascular Diabetology 2006, 5:1.
7. Cheng K.H., Chu C.S., Lee K.T., et al. Adipocytokines and proinflammatory mediators from abdominal and epicardial adipose tissue in patients with coronary artery disease. International Journal of Obesity 2008, 32:268-274. (2005).
8. Pou K.M., Massaro J.M., Hoffmann U., et al. Visceral and subcutaneous adipose tissue volumes are cross-sectionally related to markers of inflammation and oxidative stress: the Framingham Heart Study. Circulation 2007, 116:1234-1241.
9. Fantuzzi G., Mazzone T. Adipose tissue and atherosclerosis: exploring the connection. Arteriosclerosis, Thrombosis, and Vascular Biology 2007, 27:996-1003.
10. Yudkin J.S, Eringa E., Stehouwer C.D. Vasocrine" signalling from perivascular fat: a mechanism linking insulin resistance to vascular disease. The Lancet 2005, 365:1817-1820.
11. Achenbach S., Moselewski F., Ropers D., et al. Detection of calcified and noncalcified coronary atherosclerotic plaque by contrast-enhanced, submillimeter multidetector spiral computed tomography: a segment-based comparison with intravascular ultrasound. Circulation 2004, 109:14-17.
12. Achenbach S., Raggi P. Imaging of coronary atherosclerosis by computed tomography. European Heart Journal 2010, 31:1442-1448.
13. Blankstein R., Ferencik M. The vulnerable plaque: can it be detected with Cardiac CT?. Atherosclerosis 2010, 211:386-389.
14. Pundziute G., Schuijf J.D., Jukema J.W., et al. Evaluation of plaque characteristics in acute coronary syndromes: non-invasive assessment with multi-slice computed tomography and invasive evaluation with intravascular ultrasound radiofrequency data analysis. European Heart Journal 2008, 29:2373-2381.
15. Motoyama S., Kondo T., Sarai M., et al. Multislice computed tomographic characteristics of coronary lesions in acute coronary syndromes. Journal of the American College of Cardiology 2007, 50:319-326.
16. Motoyama S., Sarai M., Harigaya H., et al. Computed tomographic angiography characteristics of atherosclerotic plaques subsequently resulting in acute coronary syndrome. Journal of the American College of Cardiology 2009, 54:49-57.
17. Kitagawa T., Yamamoto H., Horiguchi J., et al. Characterization of noncalcified coronary plaques and identification of culprit lesions in patients with acute coronary syndrome by 64-slice computed tomography. JACC Cardiovascular Imaging 2009, 2:153-160.
18. Ahn S.G., Lim H.S., Joe D.Y., et al. Relationship of epicardial adipose tissue by echocardiography to coronary artery disease. Heart (British Cardiac Society) 2008, 94:e7.
19. Gorter P.M., de Vos A.M., van der Graaf Y., et al. Relation of epicardial and pericoronary fat to coronary atherosclerosis and coronary artery calcium in patients undergoing coronary angiography. The American Journal of Cardiology 2008, 102:380-385.
20. Alexopoulos N., McLean D.S., Janik M., Arepalli C.D., Stillman A.E., Raggi P. Epicardial adipose tissue and coronary artery plaque characteristics. Atherosclerosis 2010, 210:150-154.
21. Konishi M., Sugiyama S., Sugamura K., et al. Association of pericardial fat accumulation rather than abdominal obesity with coronary atherosclerotic plaque formation in patients with suspected coronary artery disease. Atherosclerosis 2010, 209:573-578.
22. Greif M., Becker A., von Ziegler F., et al. Pericardial adipose tissue determined by dual source CT is a risk factor for coronary atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology 2009, 29:781-786.
23. Ueno K., Anzai T., Jinzaki M., et al. Increased epicardial fat volume quantified by 64-multidetector computed tomography is associated with coronary atherosclerosis and totally occlusive lesions. Circulation Journal 2009, 73:1927-1933.
24. Oka T., Yamamoto H., Ohashi N., et al. Association between epicardial adipose tissue volume and characteristics of non-calcified plaques assessed by coronary computed tomographic angiography. International Journal of Cardiology 2011.
25. Hoffmann U., Bamberg F., Chae C.U., et al. Coronary computed tomography angiography for early triage of patients with acute chest pain: the ROMICAT (Rule Out Myocardial Infarction using Computer Assisted Tomography) trial. Journal of the American College of Cardiology 2009, 53:1642-1650.
26. Hoffmann U., Nagurney J.T., Moselewski F., et al. Coronary multidetector computed tomography in the assessment of patients with acute chest pain. Circulation 2006, 114:2251-2260.
27. Hoffmann U., Moselewski F., Nieman K., et al. Noninvasive assessment of plaque morphology and composition in culprit and stable lesions in acute coronary syndrome and stable lesions in stable angina by multidetector computed tomography. Journal of the American College of Cardiology 2006, 47:1655-1662.
28. Marwan M., Taher M.A., El Meniawy K., et al. In vivo CT detection of lipid-rich coronary artery atherosclerotic plaques using quantitative histogram analysis: a head to head comparison with IVUS. Atherosclerosis 2011, 215:110-115.
29. D'Agostino R.B., Vasan R.S., Pencina M.J., et al. General cardiovascular risk profile for use in primary care: the Framingham Heart Study. Circulation 2008, 117:743-753.
30. He X., Hu F. Markov Chain Marginal Bootstrap. Journal of the American Statistical Association 2002, 97:783-795.
31. Sade L.E., Eroglu S., Bozbas H., et al. Relation between epicardial fat thickness and coronary flow reserve in women with chest pain and angiographically normal coronary arteries. Atherosclerosis 2009, 204:580-585.
32. Mahabadi A.A., Massaro J.M., Rosito G.A., et al. Association of pericardial fat, intrathoracic fat, and visceral abdominal fat with cardiovascular disease burden: the Framingham Heart Study. European Heart Journal 2009, 30:850-856.
33. Janik M., Hartlage G., Alexopoulos N., et al. Epicardial adipose tissue volume and coronary artery calcium to predict myocardial ischemia on positron emission tomography-computed tomography studies. Journal of Nuclear Cardiology 2010.
34. Shmilovich H., Dey D., Cheng V.Y., et al. Threshold for the upper normal limit of indexed epicardial fat volume: derivation in a healthy population and validation in an outcome-based study. The American Journal of Cardiology 2011.
35. Bettencourt N., Toschke A., Leite D., et al. Epicardial adipose tissue is an independent predictor of coronary atherosclerotic burden. International Journal of Cardiology 2011.
36. Yerramasu A., Dey D., Venuraju S., et al. Increased volume of epicardial fat is an independent risk factor for accelerated progression of sub-clinical coronary atherosclerosis. Atherosclerosis 2012, 220:223-230.
37. Ding J., Kritchevsky S.B., Hsu F.C., et al. Association between non-subcutaneous adiposity and calcified coronary plaque: a substudy of the Multi-Ethnic Study of Atherosclerosis. The American Journal of Clinical Nutrition 2008, 88:645-650.
38. Jeong J.W., Jeong M.H., Yun K.H., et al. Echocardiographic epicardial fat thickness and coronary artery disease. Circulation Journal 2007, 71:536-539.
39. de Vos A.M., Prokop M., Roos C.J., et al. Peri-coronary epicardial adipose tissue is related to cardiovascular risk factors and coronary artery calcification in post-menopausal women. European Heart Journal 2008, 29:777-783.
40. Ogura R., Miyazaki S., Takahashi T., et al. Relationship between epicardial adipose tissue and coronary arterial remodeling as assessed by intravascular ultrasound in patients with coronary artery disease. European Heart Journal 2011, S32:31-32.
41. Stolzmann P., Subramanian S., Abdelbaky A., et al. Complementary value of cardiac FDG PET and CT for the characterization of atherosclerotic disease. Radiographics 2011, 31:1255-1269.
42. Menezes L.J., Kayani I., Ben-Haim S., Hutton B., Ell P.J., Groves A.M. What is the natural history of 18F-FDG uptake in arterial atheroma on PET/CT?. Implications for imaging the vulnerable plaque. Atherosclerosis 2010, 211:136-140.