Microbiology of regressive autism

Anaerobe

Volumn 18, Issue 2, 2012, Pages 260-262

  Finegold, Sydney M ^a,b   Downes, Julia ^a   Summanen, Paula H ^a  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Antibiotics; Etiology; Regressive autism

Indexed keywords

AMPICILLIN; ANTIINFECTIVE AGENT; CEPHALOSPORIN; CLINDAMYCIN; PENICILLIN G;

ACTINOBACTERIA; AGAR DILUTION; ANTIBIOTIC SENSITIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; AUTISM; BACTERIAL STRAIN; BACTEROIDES; BACTEROIDES VULGATUS; BIFIDOBACTERIUM ANGULATUM; BIFIDOBACTERIUM GENUS; BIFIDOBACTERIUM LONGUM; CLOSTRIDIUM; CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM LEPTUM; CLOSTRIDIUM TETANI; DESULFOVIBRIO; DESULFOVIBRIO DESULFURICANS; DESULFOVIBRIO GENUS; DESULFOVIBRIO INTESTINALIS; DESULFOVIBRIO PIGER; DIALISTER INVISUS; DISEASE PREDISPOSITION; FIRMICUTES; HUMAN; INTESTINE FLORA; MICROBIOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEOBACTERIA; REGRESSIVE AUTISM;

ANTI-BACTERIAL AGENTS; AUTISTIC DISORDER; DESULFOVIBRIO; FECES; HUMANS; MICROBIAL SENSITIVITY TESTS;

CLOSTRIDIUM DIFFICILE; DESULFOVIBRIO;

EID: 84859816611     PISSN: 10759964     EISSN: 10958274     Source Type: Journal    
DOI: 10.1016/j.anaerobe.2011.12.018     Document Type: Article

References (19)

1. Rimland B. The most air-tight study in psychiatry? Vitamin B6 in autism. Autism Res.Rev.Int 2000, 14(3):3.
2. HSPH Autism has high costs to U.S. Society 2006, Harvard School of Public Health. http://www.hsph.harvard.edu/news/press-releases/2006-releases/press04252006.html.
3. Centers for Disease Control Autism and developmental disabilities monitoring (ADDM) network 2008, Centers for Disease Control. http://www.cdc.gov/ncbddd/autism/addm.htm.
4. Kim Y.S., Leventhal B.L., Koh Y.J., Fombonne E., Laska E., Lim E.C., et al. Prevalence of autism spectrum disorders in a total population sample. Am J Psychiatry 2011, 168:904-912.
5. Bolte E.R. Autism and Clostridium tetani. Med Hypotheses 1998, 51:133-144.
6. Sandler R.H., Finegold S.M., Bolte E.R., Buchanan C.P., Maxwell A.P., Vaisaneen M.-L., et al. Short-term benefit from oral vancomycin treatment of regressive-onset autism. J Child Neurol 2000, 15:429-435.
7. Finegold S.M., Molitoris D., Song Y., Liu C., Vaisanen M.-L., Bolte E., et al. Gastrointestinal microflora studies in late-onset autism. Clin Infect Dis 2002, 35(Suppl.1):S6-S16.
8. Finegold S.M., Song Y., Liu C., Hecht D.W., Summanen P., Könönen E., et al. Clostridium clostridioforme: a mixture of three clinically important species. Eur J Clin Microbiol Infect Dis 2005, 24:319-324.
9. Parracho H.M., Bingham M.O., Gibson G.R., McCartney A.L. Differences between the gut microflora of children with autistic spectrum disorders and that of healthy children. J Med Microbiol 2005, 54:987-991.
10. MacFabe D.F., Rodriguez-Capote K., Hoffman J.E., Franklin A.E., Mohammed-Asef Y., Taylor A.R., et al. A novel rodent model of autism: intraventricular infusions of propionic acid increase locomotor activity and induce neuroinflammation and oxidative stress in discrete regions of adult rat brain. Am J Biochem Biotech 2008, 4:146-166.
11. Finegold S.M., Dowd S.E., Gontcharova V., Liu C., Henley K.E., Wolcott R.D., et al. Pyrosequencing study of fecal microflora of autistic and control children. Anaerobe 2010, 16:444-453.
12. Finegold S.M. State of the art; microbiology in health and disease. Intestinal bacterial flora in autism. Anaerobe 2011, 17(6):367-368.
13. Waring R.H., Klovrza L.V. Sulphur metabolism in autism. J Nutr Environ Med 2000, 10:25-32.
14. James S.J., Cutler P., Melnyk S., Jernigan S., Janak L., Gaylor D.W. Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism. Am J Clin Nutr 2004, 80:1611-1617.
15. Emanuele E., Orsi P., Boso M., Broglia D., Brondino N., Barale F., et al. Low-grade endotoxemia in patients with severe autism. Neurosci Lett 2010, 471:162-165.
16. Wang L., Christophersen C.T., Sorich M.J., Gerber J.P., Angley M.T., Conlon M.A. Low relative abundances of the mucolytic bacterium Akkermansia muciniphila and Bifidobacterium spp. in Feces of children with autism. Appl Environ Microbiol 2011, 77:6718-6721.
17. de Vries-Hospers H.G., Welling G.W., Swabb E.A., van der Waaij D. Selective decontamination of the digestive tract with aztreonam: a study of 10 healthy volunteers. J Infect Dis 1984, 150:636-642.
18. Niehus R., Lord C. Early medical history of children with autism spectrum disorders. Dev.Beh.Pediatr 2006, 27(2):S120-S127.
19. Finegold S.M., Mathisen G.E., George W.L. Changes in human intestinal flora related to the administration of antimicrobial agents. Human intestinal microflora in health and disease 1983, 355-446. Chap. 16, Academic Press, New York. D.J. Hentges (Ed.).