Bone marrow-derived pancreatic stellate cells in rats

Cell Research

Volumn 20, Issue 3, 2010, Pages 288-298

  Sparmann, Gisela ^a   Kruse, Marie Luise ^b   Hofmeister Mielke, Nicole ^a,c   Koczan, Dirk ^a   Jaster, Robert ^a,c   Liebe, Stefan ^a   Wolff, Daniel ^a,c   Emmrich, Jörg ^a  

^a UNIVERSITY OF ROSTOCK   (Germany)

^b Laboratory of Molecular Gastroenterology and Hepatology   (Germany)

^c UNIVERSITY HOSPITAL REGENSBURG   (Germany)

Author keywords

Bone marrow; Pancreas; Rat; Regeneration

Indexed keywords

ACTIN; DESMIN; DIBUTYLDICHLOROTIN; ENHANCED GREEN FLUORESCENT PROTEIN; GREEN FLUORESCENT PROTEIN; ORGANOTIN COMPOUND; SMOOTH MUSCLE ACTIN, RAT;

ANIMAL; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; CHIMERA; CYTOLOGY; FEMALE; FLOW CYTOMETRY; GENETICS; IMMUNOHISTOCHEMISTRY; METABOLISM; PANCREAS; PHENOTYPE; RAT; REGENERATION; STEM CELL;

ACTINS; ANIMALS; BONE MARROW CELLS; CHIMERA; DESMIN; FEMALE; FLOW CYTOMETRY; GREEN FLUORESCENT PROTEINS; IMMUNOHISTOCHEMISTRY; MODELS, ANIMAL; ORGANOTIN COMPOUNDS; PANCREAS; PHENOTYPE; RATS; REGENERATION; STEM CELLS;

RATTUS;

EID: 77949269617     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/cr.2010.10     Document Type: Article

References (32)

1. Apte MV, Haber PS, Applegate TL, et al. Periacinar stellate shaped cells in rat pancreas: identification, isolation, and culture. Gut 1998; 43:128-133.
2. Bachem MG, Schneider E, Gross H, et al. Identification, culture, and characterization of pancreatic stellate cells in rats and humans. Gastroenterology 1998; 115:421-432.
3. Jaster R. Molecular regulation of pancreatic stellate cell function. Mol Cancer 2004; 3:1-8.
4. Klonowski-Stumpe H, Fischer R, Reinehr R, Luthen R, Haussinger D. Apoptosis in activated rat pancreatic stellate cells. Am J Physiol Gastrointest Liver Physiol 2002; 283:G819-G826.
5. Ramiya VK, Maraist M, Arfors KE, Schatz DA, Peck AB, Cornelius JG. Reversal of insulin-dependent diabetes using islets generated in vitro from pancreatic stem cells. Nat Med 2000; 6:278-282.
6. Hess D, Li L, Martin M, Sakano S, et al. Bone marrow-de rived stem cells initiate pancreatic regeneration. Nat Biotechnol 2003; 21:763-770.
7. Dor Y, Brown J, Martinez OI, Melton DA. Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation. Nature 2004; 429:41-46.
8. Sumi S, Gu Y, Hiura A, Inoue K. Stem cells and regenerative medicine for diabetes mellitus. Pancreas 2004; 29:e85-e89.
9. Jensen JN, Cameron E, Garay MV, Starkey TW, Gianani R, Jensen J. Recapitulation of elements of embryonic development in adult mouse pancreatic regeneration. Gastroenterology 2005; 128:728-741.
10. Yalniz M, Pour PM. Are there any stem cells in the pancreas? Pancreas 2005; 31:108-118.
11. Mato E, Lucas M, Petriz J, Gomis R, Novials A. Identification of a pancreatic stellate cell population with properties of progenitor cells: new role for stellate cells in the pancreas. Biochem J 2009; 421:181-191.
12. Russo FP, Alison MR, Bigger BW, et al. The bone marrow functionally contributes to liver fibrosis. Gastroenterology 2006; 130:1807-1821.
13. Lama VN, Phan SH. The extrapulmonary origin of fibroblasts: stem/progenitor cells and beyond. Proc Am Thorac Soc 2006; 3:373-376.
14. van Amerongen M, Bou-Gharios G, Popa E, et al. Bone marrow-derived myofibroblasts contribute functionally to scar formation after myocardial infarction. J Pathol 2008; 214:377-386.
15. Marrache F, Pendyala S, Bhagat G, Betz KS, Song Z, Wang TC. Role of bone marrow-derived cells in experimental chronic pancreatitis. Gut 2008; 57:1113-1120.
16. Sparmann G, Hohenadl C, Tornoe J, et al. Generation and characterization of immortalized rat pancreatic stellate cells. Am J Physiol Gastrointest Liver Physiol 2004; 287:G211-G219.
17. Hense S, Sparmann G, Weber H, Liebe S, Emmrich J. Immunologic characterization of acute pancreatitis in rats induced by dibutyltin dichloride (DBTC). Pancreas 2003; 27:e6-e12.
18. Seki E, de Minicis S, Inokuchi S, et al. CCR2 promotes hepatic fibrosis in mice. Hepatology 2009; 50:185-197.
19. Elsasser HP, Adler G, Kern HF. Time course and cellular source of pancreatic regeneration following acute pancreatitis in the rat. Pancreas 1986; 1:421-429.
20. Luttenberger T, Schmid-Kotsas A, Menke A, et al. Plateletderived growth factors stimulate proliferation and extracellular matrix synthesis of pancreatic stellate cells: implications in pathogenesis of pancreas fibrosis. Lab Invest 2000; 80:47-55.
21. Mews P, Phillips P, Fahmy R, et al. Pancreatic stellate cells respond to inflammatory cytokines: potential role in chronic pancreatitis. Gut 2002; 50:535-541.
22. Sparmann G, Glass A, Brock P, et al. Inhibition of lymphocyte apoptosis by pancreatic stellate cells: impact of interleukin- 15. Am J Physiol Gastrointest Liver Physiol 2005; 289:G842-G851.
23. Alison MR, Poulsom R, Otto WR, et al. Plastic adult stem cells: will they graduate from the school of hard knocks? J Cell Sci 2003; 116:599-603.
24. Direkze NC, Jeffery R, Hodivala-Dilke K, et al. Bone marrow- derived stromal cells express lineage-related messenger RNA species. Cancer Res 2006; 66:1265-1269.
25. Bucala R, Spiegel LA, Chesney J, Hogan M, Cerami A. Circulating fibrocytes define a new leukocyte subpopulation that mediates tissue repair. Mol Med 1994; 1:71-81.
26. Abe R, Donnelly SC, Peng T, Bucala R, Metz CN. Peripheral blood fibrocytes: differentiation pathway and migration to wound sites. J Immunol 2001; 166:7556-7562.
27. Barth PJ, Ebrahimsade S, Hellinger A, Moll R, Ramaswamy A. CD34+ fibrocytes in neoplastic and inflammatory pancreatic lesions. Virchows Arch 2002; 440:128-133.
28. Jiang Y, Jahagirdar BN, Reinhardt RL, et al. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 2002; 418:41-49.
29. van den Brandt J, Wang D, Kwon SH, Heinkelein M, Reichardt HM. Lentivirally generated eGFP-transgenic rats allow efficient cell tracking in vivo. Genesis 2004; 39:94-99.
30. Wolff D, Frei E, Hofmeister N, et al. Methotrexate-albumin and aminopterin-albumin effectively prevent experimental acute graft-versus-host disease. Transplantation 2006; 82:527-533.
31. Sparmann G, Merkord J, Jaschke A, et al. Pancreatic fibrosis in experimental pancreatitis induced by dibutyltin dichloride. Gastroenterology 1997; 112:1664-1672.
32. Emmrich J, Weber I, Nausch M, et al. Immunohistochemical characterization of the pancreatic cellular infiltrate in normal pancreas, chronic pancreatitis and pancreatic carcinoma. Digestion 1998; 59:192-198.