Trypanosoma cruzi coexpressing ornithine decarboxylase and green fluorescence proteins as a tool to study the role of polyamines in chagas disease pathology

Enzyme Research

Volumn 2011, Issue 1, 2011, Pages

  Barclay, Jeremías José ^a   Morosi, Luciano Gastón ^a   Vanrell, María Cristina ^b   Trejo, Edith Corina ^a   Romano, Patricia Silvia ^b   Carrillo, Carolina ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b Instituto de Histologia y Embriologia   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

GREEN FLUORESCENT PROTEIN; ORNITHINE; ORNITHINE DECARBOXYLASE; POLYAMINE;

ANIMAL CELL; ARTICLE; AUXOTROPHY; CHAGAS DISEASE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME KINETICS; FLUORESCENCE ANALYSIS; GENETIC TRANSFECTION; NONHUMAN; PARASITE SURVIVAL; PARASITE TRANSMISSION; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRYPANOSOMA CRUZI; VERO CELL;

TRYPANOSOMA CRUZI;

EID: 84859803382     PISSN: 20900406     EISSN: 20900414     Source Type: Journal    
DOI: 10.4061/2011/657460     Document Type: Article

References (68)

1. Heby O., Persson L., Rentala M., Targeting the polyamine biosynthetic enzymes: a promising approach to therapy of African sleeping sickness, Chagas' disease, and leishmaniasis. Amino Acids 2007 33 2 359 366 2-s2.0-34547654456 10.1007/s00726-007-0537-9 (Pubitemid 47222983)
2. Schofield C. J., Maudlin I., Trypanosomiasis control. International Journal for Parasitology 2001 31 5-6 615 620 2-s2.0-0035340738 (Pubitemid 32382064)
3. Andrade L. O., Andrews N. W., Opinion: the Trypanosoma cruzi - host-cell interplay: location, invasion, retention. Nature Reviews Microbiology 2005 3 10 819 823 2-s2.0-27244448634 10.1038/nrmicro1249 (Pubitemid 41518742)
4. Tyler K. M., Engman D. M., The life cycle of Trypanosoma cruzi revisited. International Journal for Parasitology 2001 31 5-6 472 481 2-s2.0-0035340990 10.1016/S0020-7519(01)00153-9 (Pubitemid 32382045)
5. Kohl L., Robinson D., Bastin P., Novel roles for the flagellum in cell morphogenesis and cytokinesis of trypanosomes. The EMBO Journal 2003 22 20 5336 5346 2-s2.0-0142105416 10.1093/emboj/cdg518 (Pubitemid 37279944)
6. Romano P. S., Arboit M. A., Vázquez C. L., Colombo M. I., The autophagic pathway is a key component in the lysosomal dependent entry of Trypanosoma cruzi into the host cell. Autophagy 2009 5 1 6 18 2-s2.0-58149398242
7. Pires S. F., DaRocha W. D., Freitas J. M., Oliveira L. A., Kitten G. T., Machado C. R., Pena S. D. J., Chiari E., Macedo A. M., Teixeira S. M. R., Cell culture and animal infection with distinct Trypanosoma cruzi strains expressing red and green fluorescent proteins. International Journal for Parasitology 2008 38 3-4 289 297 2-s2.0-38949217383 10.1016/j.ijpara.2007.08.013 (Pubitemid 351215435)
8. Ramirez M. I., Yamauchi L. M., De Freitas L. H. G., Uemura H., Schenkman S., The use of the green fluorescent protein to monitor and improve transfection in Trypanosoma cruzi. Molecular and Biochemical Parasitology 2000 111 1 235 240 2-s2.0-0033763977 10.1016/S0166-6851(00)00309-1
9. Geiger L. E., Morris D. R., Stimulation of deoxyribonucleic acid replication fork movement by spermidine analogs in polyamine-deficient Escherichia coli. Journal of Bacteriology 1980 141 3 1192 1198 2-s2.0-0018829957 (Pubitemid 10076143)
10. Algranati I. D., Goldemberg S. H., Initiation, elongation and termination of polypeptide synthesis in cell-free systems from polyamine-deficient bacteria. Biochemical and Biophysical Research Communications 1981 103 1 8 15 2-s2.0-0019784427 (Pubitemid 12211067)
11. Tabor C. W., Tabor H., Polyamines. Annual Review of Biochemistry 1984 53 749 790 (Pubitemid 14059150)
12. Wallace H. M., Fraser A. V., Hughes A., A perspective of polyamine metabolism. Biochemical Journal 2003 376 1 1 14 2-s2.0-0345688128 10.1042/BJ20031327 (Pubitemid 37487199)
13. Eisenberg T., Knauer H., Schauer A., Büttner S., Ruckenstuhl C., Carmona-Gutierrez D., Ring J., Schroeder S., Magnes C., Antonacci L., Fussi H., Deszcz L., Hartl R., Schraml E., Criollo A., Megalou E., Weiskopf D., Laun P., Heeren G., Breitenbach M., Grubeck-Loebenstein B., Herker E., Fahrenkrog B., Fröhlich K. U., Sinner F., Tavernarakis N., Minois N., Kroemer G., Madeo F., Induction of autophagy by spermidine promotes longevity. Nature Cell Biology 2009 11 11 1305 1314 2-s2.0-70449529855 10.1038/ncb1975
14. Bacchi C. J., McCann P. P., McCann P. P., Pegg A. E., Sjoerdsma A., Inhibition of polyamine metabolism: biological significance and bases for new therapies. Polyamines 1987 Orlando, Fla, USA Academic Press 317 344
15. Algranati I. D., Polyamine metabolism in Trypanosoma cruzi: studies on the expression and regulation of heterologous genes involved in polyamine biosynthesis. Amino Acids 2010 38 2 645 651 2-s2.0-77953064754 10.1007/s00726-009-0425-6
16. Bacchi C. J., Nathan H. C., Hutner S. H., Polyamine metabolism: a potential therapeutic target in trypanosomes. Science 1980 210 4467 332 334 2-s2.0-0019194217 (Pubitemid 11208468)
17. Milord F., Pépin J., Loko L., Ethier L., Mpia B., Efficacy and toxicity of eflornithine for treatment of Trypanosoma brucei gambiense sleeping sickness. The Lancet 1992 340 8820 652 655 2-s2.0-0026660462 10.1016/0140-6736(92)92180-N
18. Sjoerdsma A., Schechter P. J., Eflornithine for African sleeping sickness. The Lancet 1999 354 9174 254 2-s2.0-0033578253
19. Pegg A. E., Recent advances in the biochemistry of polyamines in eukaryocytes. Biochemical Journal 1986 234 2 249 262 2-s2.0-0022450919 (Pubitemid 16049822)
20. Ariyanayagam M. R., Oza S. L., Mehlert A., Fairlamb A. H., Bis(glutathionyl)spermine and other novel trypanothione analogues in Trypanosoma cruzi. Journal of Biological Chemistry 2003 278 30 27612 27619 2-s2.0-0041461862 10.1074/jbc.M302750200 (Pubitemid 36899947)
21. Hamana K., Matsuzaki S., Polyamines as a chemotaxonomic marker in bacterial systematics. Critical Reviews in Microbiology 1992 18 4 261 283 2-s2.0-0026788035
22. Marton L. J., Pegg A. E., Polyamines as targets for therapeutic intervention. Annual Review of Pharmacology and Toxicology 1995 35 55 91 2-s2.0-0028956729
23. Janne J., Poso H., Raina A., Polyamines in rapid growth and cancer. Biochimica et Biophysica Acta 1978 473 3-4 241 293 2-s2.0-0018088697 (Pubitemid 8304209)
24. Pegg A. E., Polyamine metabolism and its importance in neoplastic growth and as a target for chemotherapy. Cancer Research 1988 48 4 759 774 2-s2.0-0023881236 (Pubitemid 18061860)
25. Cunin R., Glansdorff N., Pierard A., Stalon V., Biosynthesis and metabolism of arginine in bacteria. Microbiological Reviews 1986 50 3 314 352 2-s2.0-0022531132 (Pubitemid 16017072)
26. Smith T. A., L-arginine carboxy-lyase of higher plants and its relation to potassium nutrition. Phytochemistry 1963 2 3 241 252 2-s2.0-0000450238
27. Iyo A. H., Zhu M. Y., Ordway G. A., Regunathan S., Expression of arginine decarboxylase in brain regions and neuronal cells. Journal of Neurochemistry 2006 96 4 1042 1050 2-s2.0-33645098156 10.1111/j.1471-4159.2005.03544.x
28. Zhu M. Y., Iyo A., Piletz J. E., Regunathan S., Expression of human arginine decarboxylase, the biosynthetic enzyme for agmatine. Biochimica et Biophysica Acta 2004 1670 2 156 164 2-s2.0-1642450643 10.1016/j.bbagen.2003.11. 006 (Pubitemid 38115860)
29. Mella C., Martínez F., De Los Angeles García M., Nualart F., Castro V., Bustos P., Carvajal N., Uribe E., auribe@udec.cl Expression and localization of an agmatinase-like protein in the rat brain. Histochemistry and Cell Biology 2010 134 2 137 144 10.1007/s00418-010-0720-z
30. El-Sayed N. M., Myler P. J., Bartholomeu D. C., Nilsson D., Aggarwal G., Tran A. N., Ghedin E., Worthey E. A., Delcher A. L., Blandin G., Westenberger S. J., Caler E., Cerqueira G. C., Branche C., Haas B., Anupama A., Arner E., Åslund L., Attipoe P., Bontempi E., Bringaud F., Burton P., Cadag E., Campbell D. A., Carrington M., Crabtree J., Darban H., Da Silveira J. F., De Jong P., Edwards K., Englund P. T., Fazelina G., Feldblyum T., Ferella M., Frasch A. C., Gull K., Horn D., Hou L., Huang Y., Kindlund E., Klingbeil M., Kluge S., Koo H., Lacerda D., Levin M. J., Lorenzi H., Louie T., Machado C. R., McCulloch R., McKenna A., Mizuno Y., Mottram J. C., Nelson S., Ochaya S., Osoegawa K., Pai G., Parsons M., Pentony M., Pettersson U., Pop M., Ramirez J. L., Rinta J., Robertson L., Salzberg S. L., Sánchez D. O., Seyler A., Sharma R., Shetty J., Simpson A. J., Sisk E., Tammi M. T., Tarleton R., Teixeira S., Van Aken S., Vogt C., Ward P. N., Wickstead B., Wortman J., White O., Fraser C. M., Stuart K. D., Andersson B., The genome sequence of Trypanosoma cruzi, etiologic agent of chagas disease. Science 2005 309 5733 409 435 2-s2.0-22244453726 10.1126/science.1112631 (Pubitemid 40994675)
31. Della Ragione F., Pegg A. E., Purification and characterization of spermidine/spermine N-acetyltransferase from rat liver. Biochemistry 1982 21 24 6152 6158 2-s2.0-0020406954 (Pubitemid 13141618)
32. Vujcic S., Liang P., Diegelman P., Kramer D. L., Porter C. W., Genomic identification and biochemical characterization of the mammalian polyamine oxidase involved in polyamine back-conversion. Biochemical Journal 2003 370 1 19 28 2-s2.0-0037442525 10.1042/BJ20021779 (Pubitemid 36259415)
33. Fairlamb A. H., Cerami A., Metabolism and functions of trypanothione in the kinetoplastida. Annual Review of Microbiology 1992 46 695 729 2-s2.0-0026793462
34. Fairlamb A. H., Blackburn P., Ulrich P., Chait B. T., Cerami A., Trypanothione: a novel bis(glutathionyl)spermidine cofactor for glutathione reductase in trypanosomatids. Science 1985 227 4693 1485 1487 2-s2.0-0022002912 (Pubitemid 15146992)
35. Fairlamb A. H., Cerami A., Identification of a novel, thiol-containing co-factor essential for glutathione reductase enzyme activity in trypanosomatids. Molecular and Biochemical Parasitology 1985 14 2 187 198 2-s2.0-0021933665 (Pubitemid 15174629)
36. González N. S., Huber A., Algranati I. D., Spermidine is essential for normal proliferation of trypanosomatid protozoa. FEBS Letters 2001 508 3 323 326 2-s2.0-0035941059 10.1016/S0014-5793(01)03091-5 (Pubitemid 33135463)
37. Igarashi K., Kashiwagi K., Polyamines: mysterious modulators of cellular functions. Biochemical and Biophysical Research Communications 2000 271 3 559 564 2-s2.0-0034685624 10.1006/bbrc.2000.2601 (Pubitemid 30444667)
38. Carrillo C., Cejas S., González N. S., Algranati I. D., Trypanosoma cruzi epimastigotes lack ornithine decarboxylase but can express a foreign gene encoding this enzyme. FEBS Letters 1999 454 3 192 196 2-s2.0-0033049344 10.1016/S0014-5793(99)00804-2 (Pubitemid 29304598)
39. Algranati I. D., Sánchez C., González N. S., Goldemberg S. H., Algranati I. D., Polyamines in Trypanosoma cruzi and Leishmania mexicana. The Biology and Chemistry of Polyamines 1990 Oxford, UK Oxford University Press 137 146
40. Ariyanayagam M. R., Fairlamb A. H., Diamine auxotrophy may be a universal feature of Trypanosoma cruzi epimastigotes. Molecular and Biochemical Parasitology 1997 84 1 111 121 2-s2.0-0031057528 10.1016/S0166-6851(96)02788-0 (Pubitemid 27090511)
41. Carrillo C., Cejas S., Huber A., González N. S., Algranati I. D., Lack of arginine decarboxylase in Trypanosoma cruzi epimastigotes. Journal of Eukaryotic Microbiology 2003 50 5 312 316 2-s2.0-0141787976 10.1111/j.1550-7408. 2003.tb00141.x (Pubitemid 37144034)
42. Carrillo C., Serra M. P., Pereira C. A., Huber A., González N. S., Algranati I. D., Heterologous expression of a plant arginine decarboxylase gene in Trypanosoma cruzi. Biochimica et Biophysica Acta 2004 1674 3 223 230 2-s2.0-7944222074 10.1016/j.bbagen.2004.06.017 (Pubitemid 39469281)
43. Yakubu M. A., Majumder S., Kierszenbaum F., Inhibition of S-adenosyl-L-methionine (AdoMet) decarboxylase by the decarboxylated AdoMet analog 5'-{[(Z)-4-amino-2-butenyl]methylamino}-5'-deoxyadenosine (MDL 73811) decreases the capacities of Trypanosoma cruzi to infect and multiply within a mammalian host cell. Journal of Parasitology 1993 79 4 525 532 2-s2.0-0027198139 (Pubitemid 23249739)
44. Kierszenbaum F., Wirth J. J., McCann P. P., Sjoerdsma A., Arginine decarboxylase inhibitors reduce the capacity of Trypanosoma cruzi to infect and multiply in mammalian host cells. Proceedings of the National Academy of Sciences of the United States of America 1987 84 12 4278 4282 2-s2.0-0011740954 (Pubitemid 17090917)
45. Kierszenbaum F., Wirth J. J., McCann P. P., Sjoerdsma A., Impairment of macrophage function by inhibitors of ornithine decarboxylase activity. Infection and Immunity 1987 55 10 2461 2464 2-s2.0-0023227549 (Pubitemid 17136326)
46. Olenyik T., Gilroy C., Ullman B., ullmanb@ohsu.edu Oral putrescine restores virulence of ornithine decarboxylase-deficient Leishmania donovani in mice. Molecular and Biochemical Parasitology 2011 176 2 109 111 10.1016/j.molbiopara.2010.12.004
47. Fairlamb A. H., Metabolic pathway analysis in trypanosomes and malaria parasites. Philosophical Transactions of the Royal Society B 2002 357 1417 101 107 2-s2.0-0037192115 10.1098/rstb.2001.1040 (Pubitemid 34147269)
48. DaRocha W. D., Silva R. A., Bartholomeu D. C., Pires S. F., Freitas J. M., Macedo A. M., Vazquez M. P., Levin M. J., Teixeira S. M. R., Expression of exogenous genes in Trypanosoma cruzi: improving vectors and electroporation protocols. Parasitology Research 2004 92 2 113 120 2-s2.0-0442329282 10.1007/s00436-003-1004-5 (Pubitemid 38187004)
49. Svensson F., Ceriani C., Wallström E. L., Kockum I., Algranati I. D., Heby O., Persson LO., Cloning of a trypanosomatid gene coding for an ornithine decarboxylase that is metabolically unstable even though it lacks the C-terminal degradation domain. Proceedings of the National Academy of Sciences of the United States of America 1997 94 2 397 402 2-s2.0-0031035013 10.1073/pnas.94.2.397 (Pubitemid 27053643)
50. Martínez-Calvillo S., López I., Hernández R., pRIBOTEX expression vector: a pTEX derivative for a rapid selection of Trypanosoma cruzi transfectants. Gene 1997 199 1-2 71 76 2-s2.0-0343416375 10.1016/S0378-1119(97)00348-X (Pubitemid 27448203)
51. Lorenzi H. A., Vazquez M. P., Levin M. J., Integration of expression vectors into the ribosomal locus of Trypanosoma cruzi. Gene 2003 310 1-2 91 99 2-s2.0-0037498106 10.1016/S0378-1119(03)00502-X (Pubitemid 36703303)
52. Marcora M. S., Cejas S., González N. S., Carrillo C., Algranati I. D., Polyamine biosynthesis in Phytomonas: biochemical characterisation of a very unstable ornithine decarboxylase. International Journal for Parasitology 2010 40 1389 1394 2-s2.0-77952102754 10.1016/j.ijpara.2010.04.003
53. Bradford M. M., A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding. Analytical Biochemistry 1976 72 1-2 248 254 2-s2.0-0017184389
54. Sánchez C. P., Mucci J., González N. S., Ochoa A., Zakin M. M., Algranati I. D., α -difluoromethylornithine-resistant cell lines obtained after one-step selection of Leishmania mexicana promastigote cultures. Biochemical Journal 1997 324 3 847 853 2-s2.0-0030754481 (Pubitemid 27285543)
55. Contreras V. T., Morel C. M., Goldenberg S., Stage specific gene expression precedes morphological changes during Trypanosoma cruzi metacyclogenesis. Molecular and Biochemical Parasitology 1985 14 1 83 96 2-s2.0-0021933036 (Pubitemid 15171432)
56. Ferreira L. R. P., Silva A. M., Michailowsky V., Reis L. F. L., Gazzinelli R. T., Expression of serum amyloid A3 mRNA by inflammatory macrophages exposed to membrane glycoconjugates from Trypanosoma cruzi. Journal of Leukocyte Biology 1999 66 4 593 600 2-s2.0-0032833130 (Pubitemid 29489886)
57. Opperdoes F. R., Michels P. A. M., Enzymes of carbohydrate metabolism as potential drug targets. International Journal for Parasitology 2001 31 5-6 482 490 2-s2.0-0035339822 (Pubitemid 32382046)
58. Carrillo C., González N. S., Algranati I. D., Trypanosoma cruzi as a model system to study the expression of exogenous genes coding for polyamine biosynthetic enzymes. Induction of DFMO resistance in transgenic parasites. Biochimica et Biophysica Acta 2007 1770 12 1605 1611 2-s2.0-35448955196 10.1016/j.bbagen.2007.08.013 (Pubitemid 47633818)
59. Carrillo C., Cejas S., Cortés M., Ceriani C., Huber A., González N. S., Algranati I. D., Sensitivity of trypanosomatid protozoa to DFMO and metabolic turnover of ornithine decarboxylase. Biochemical and Biophysical Research Communications 2000 279 2 663 668 2-s2.0-0034694943 10.1006/bbrc.2000.3996 (Pubitemid 32016771)
60. Ceriani C., González N. S., Algranati I. D., Ornithine decarboxylase from Crithidia fasciculata is metabolically unstable and resistant to polyamine down-regulation. FEBS Letters 1992 301 3 261 264 2-s2.0-0026603431 10.1016/0014-5793(92)80253-D
61. Stempin C. C., Dulgerian L. R., Garrido V. V., Cerban F. M., Arginase in parasitic infections: macrophage activation, immunosuppression, and intracellular signals. Journal of Biomedicine and Biotechnology 2010 2010 10 683485 2-s2.0-77449126859
62. Peluffo G., Piacenza L., Irigoín F., Alvarez M. N., Radi R., L-arginine metabolism during interaction of Trypanosoma cruzi with host cells. Trends in Parasitology 2004 20 8 363 369 2-s2.0-3142757951 10.1016/j.pt.2004.05. 010 (Pubitemid 38916525)
63. Bacchi C. J., Braunstein V. L., Rattendi D., Yarlett N., Wittner M., Tanowitz H. B., Stage-specific polyamine metabolism in Trypanosoma cruzi. Journal of Eukaryotic Microbiology 2001 48 201S 202S 2-s2.0-0035544896 (Pubitemid 34281142)
64. Pegg A. E., Regulation of ornithine decarboxylase. Journal of Biological Chemistry 2006 281 21 14529 14532 2-s2.0-33744951504 10.1074/jbc.R500031200 (Pubitemid 43855154)
65. Hernández S., Schwarcz de Tarlovsky S., Arginine decarboxylase in Trypanosoma cruzi, characteristics and kinetic properties. Cellular and Molecular Biology 1999 45 4 383 391 2-s2.0-0033146548
66. Piacenza L., Peluffo G., Radi R., L-arginine-dependent suppression of apoptosis in Trypanosoma cruzi: contribution of the nitric oxide and polyamine pathways. Proceedings of the National Academy of Sciences of the United States of America 2001 98 13 7301 7306 2-s2.0-0035912807 10.1073/pnas.121520398 (Pubitemid 32567943)
67. Le Quesne S. A., Fairlamb A. H., Regulation of a high-affinity diamine transport system in Trypanosoma cruzi epimastigotes. Biochemical Journal 1996 316 2 481 486 2-s2.0-0029898712 (Pubitemid 26182145)
68. Majumder S., Wirth J. J., Bitonti A. J., McCann P. P., Kierszenbaum F., Biochemical evidence for the presence of arginine decarboxylase activity in Trypanosoma cruzi. Journal of Parasitology 1992 78 2 371 374 2-s2.0-0026842163