Evidence for local dendritic cell activation in pulmonary sarcoidosis

Respiratory Research

Volumn 13, Issue , 2012, Pages

  Berge, Bregje T ^a   KleinJan, Alex ^a   Muskens, Femke ^a   Hammad, Hamida ^b   Hoogsteden, Henk C ^a   Hendriks, Rudi W ^a   Lambrecht, Bart N ^a,b   Van den Blink, Bernt ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b GHENT UNIVERSITY HOSPITAL   (Belgium)

Author keywords

Bronchoalveolar lavage; Dendritic cells; Granuloma; Sarcoidosis; TNF

Indexed keywords

CD86 ANTIGEN; GLYCOPROTEIN P 15095; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; BLOOD SAMPLING; CD4+ T LYMPHOCYTE; CELL ACTIVATION; CELL COUNT; CELL CULTURE; CELL ISOLATION; CELL MATURATION; CELL SELECTION; CLINICAL ARTICLE; COCULTURE; CONTROLLED STUDY; CYTOKINE RELEASE; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOPATHOGENESIS; IMMUNOREACTIVITY; LUNG GRANULOMA; LUNG LAVAGE; LUNG SARCOIDOSIS; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE PROLIFERATION; MALE; MIXED LYMPHOCYTE REACTION; MONOCYTE; MYELOID DENDRITIC CELL; PLASMACYTOID DENDRITIC CELL; RESPIRATORY TRACT BIOPSY; ADOLESCENT; AGED; BIOPSY; BLOOD; BONE MARROW CELL; CASE CONTROL STUDY; CELL PROLIFERATION; DENDRITIC CELL; GRANULOMA; IMMUNOLOGY; LUNG; MIDDLE AGED; PATHOLOGY; SARCOIDOSIS;

ADOLESCENT; ADULT; AGED; BIOPSY; BRONCHOALVEOLAR LAVAGE FLUID; CASE-CONTROL STUDIES; CELL COUNT; CELL PROLIFERATION; DENDRITIC CELLS; FEMALE; GRANULOMA; HUMANS; LUNG; MALE; MIDDLE AGED; MYELOID CELLS; SARCOIDOSIS, PULMONARY; YOUNG ADULT;

EID: 84859787310     PISSN: 14659921     EISSN: 1465993X     Source Type: Journal    
DOI: 10.1186/1465-9921-13-33     Document Type: Article

References (44)

1. Baughman RP, Teirstein AS, Judson MA, Rossman MD, Yeager H, Bresnitz EA, DePalo L, Hunninghake G, Iannuzzi MC, Johns CJ, et al. Clinical characteristics of patients in a case control study of sarcoidosis. Am J Respir Crit Care Med 2001, 164(10 Pt 1):1885-1889.
2. Statement on sarcoidosis. Joint Statement of the American Thoracic Society (ATS), the European Respiratory Society (ERS) and the World Association of Sarcoidosis and Other Granulomatous Disorders (WASOG) adopted by the ATS Board of Directors and by the ERS Executive Committee, February 1999. Am J Respir Crit Care Med 1999, 160(2):736-755.
3. Iannuzzi MC, Rybicki BA, Teirstein AS. Sarcoidosis. N Engl J Med 2007, 357(21):2153-2165. 10.1056/NEJMra071714, 18032765.
4. Baughman RP, Culver DA, Judson MA. A Concise Review of Pulmonary Sarcoidosis. Am J Respir Critical Care Med 2011, 183(5):573-581.
5. Rybicki BA, Iannuzzi MC, Frederick MM, Thompson BW, Rossman MD, Bresnitz EA, Terrin ML, Moller DR, Barnard J, Baughman RP, et al. Familial aggregation of sarcoidosis. A case-control etiologic study of sarcoidosis (ACCESS). Am J Respir Crit Care Med 2001, 164(11):2085-2091.
6. Moller DR. Potential etiologic agents in sarcoidosis. Proc Am Thorac Soc 2007, 4(5):465-468. 10.1513/pats.200608-155MS, 2647598, 17684291.
7. Oswald-Richter KA, Drake WP. The etiologic role of infectious antigens in sarcoidosis pathogenesis. Semin Respir Crit Care Med 2010, 31(4):375-379. 10.1055/s-0030-1262205, 20665387.
8. Zissel G, Ernst M, Schlaak M, Muller-Quernheim J. Accessory function of alveolar macrophages from patients with sarcoidosis and other granulomatous and nongranulomatous lung diseases. J Investig Med 1997, 45(2):75-86.
9. Agostini C, Trentin L, Perin A, Facco M, Siviero M, Piazza F, Basso U, Adami F, Zambello R, Semenzato G. Regulation of alveolar macrophage-T cell interactions during Th1-type sarcoid inflammatory process. Am J Physiol 1999, 277(2 Pt 1):L240-L250.
10. Prasse A, Georges CG, Biller H, Hamm H, Matthys H, Luttmann W, Virchow JC. Th1 cytokine pattern in sarcoidosis is expressed by bronchoalveolar CD4+ and CD8+ T cells. Clin Exp Immunol 2000, 122(2):241-248. 10.1046/j.1365-2249.2000.01365.x, 1905777, 11091281.
11. Inui N, Chida K, Suda T, Nakamura H. TH1/TH2 and TC1/TC2 profiles in peripheral blood and bronchoalveolar lavage fluid cells in pulmonary sarcoidosis. J Allergy Clin Immunol 2001, 107(2):337-344. 10.1067/mai.2001.112273, 11174202.
12. Wahlstrom J, Katchar K, Wigzell H, Olerup O, Eklund A, Grunewald J. Analysis of intracellular cytokines in CD4+ and CD8+ lung and blood T cells in sarcoidosis. A J Respir Crit Care Med 2001, 163(1):115-121.
13. Nicod LP, Isler P. Alveolar macrophages in sarcoidosis coexpress high levels of CD86 (B7.2), CD40, and CD30L. Am J Respir Cell Mol Biol 1997, 17(1):91-96.
14. Zaba LC, Smith GP, Sanchez M, Prystowsky SD. Dendritic Cells in the Pathogenesis of Sarcoidosis. Am J Respir Cell Mol Biol 2010, 42(1):32-39. 10.1165/rcmb.2009-0033TR, 2809219, 19372243.
15. GeurtsvanKessel CH, Lambrecht BN. Division of labor between dendritic cell subsets of the lung. Mucosal Immunol 2008, 1(6):442-450. 10.1038/mi.2008.39, 19079211.
16. Ito T, Schaller M, Hogaboam CM, Standiford TJ, Sandor M, Lukacs NW, Chensue SW, Kunkel SL. TLR9 regulates the mycobacteria-elicited pulmonary granulomatous immune response in mice through DC-derived Notch ligand delta-like 4. J Clin Invest 2009, 119(1):33-46. 2613456, 19075396.
17. Iyonaga K, McCarthy KM, Schneeberger EE. Dendritic cells and the regulation of a granulomatous immune response in the lung. Am J Respir Cell Molecul Biol 2002, 26(6):671-679.
18. Tsuchiya T, Chida K, Suda T, Schneeberger EE, Nakamura H. Dendritic cell involvement in pulmonary granuloma formation elicited by bacillus calmette-guerin in rats. Am J Respir Crit Care Med 2002, 165(12):1640-1646. 10.1164/rccm.2110086, 12070066.
19. Willart MA, Jan-de-Heer H, Hammad H, Soullie T, Deswarte K, Clausen BE, Boon L, Hoogsteden HC, Lambrecht BN. The lung vascular filter as a site of immune induction for T cell responses to large embolic antigen. J Exp Med 2009, 206(12):2823-2835. 10.1084/jem.20082401, 2806611, 19858325.
20. Munro CS, Campbell DA, Du Bois RM, Mitchell DN, Cole PJ, Poulter LW. Dendritic cells in cutaneous, lymph node and pulmonary lesions of sarcoidosis. Scand J Immunol 1987, 25(5):461-467. 10.1111/j.1365-3083.1987.tb02217.x, 3589506.
21. Ota M, Amakawa R, Uehira K, Ito T, Yagi Y, Oshiro A, Date Y, Oyaizu H, Shigeki T, Ozaki Y, et al. Involvement of dendritic cells in sarcoidosis. Thorax 2004, 59(5):408-413. 10.1136/thx.2003.006049, 1746987, 15115868.
22. Tateyama M, Fujihara K, Itoyama Y. Dendritic cells in muscle lesions of sarcoidosis. Human pathology 2011, 42(3):340-346. 10.1016/j.humpath.2010.07.011, 21111453.
23. Mathew S, Bauer KL, Fischoeder A, Bhardwaj N, Oliver SJ. The anergic state in sarcoidosis is associated with diminished dendritic cell function. J Immunol 2008, 181(1):746-755. 2593870, 18566441.
24. Lommatzsch M, Bratke K, Bier A, Julius P, Kuepper M, Luttmann W, Virchow JC. Airway dendritic cell phenotypes in inflammatory diseases of the human lung. Eur Respir J 2007, 30(5):878-886. 10.1183/09031936.00036307, 17626112.
25. Zaba LC, Smith GP, Sanchez M, Prystowsky SD. Dendritic cells in the pathogenesis of sarcoidosis. Am J Respir Cell Molecul Biol 2010, 42(1):32-39.
26. Kulakova N, Urban B, McMichael AJ, Ho LP. Functional analysis of dendritic cell-T cell interaction in sarcoidosis. Clin Exp Immunol 2009, 159(1):82-86. 2802697, 19878509.
27. Ten Berge B, Muskens F, Kleinjan A, Hammad H, Hoogsteden HC, Lambrecht BN, Van den Blink B. A novel method for isolating dendritic cells from human bronchoalveolar lavage fluid. J Immunol Methods 2009, 351(1-2):13-23. 10.1016/j.jim.2009.09.009, 19804781.
28. KleinJan A, Willart M, van Rijt LS, Braunstahl GJ, Leman K, Jung S, Hoogsteden HC, Lambrecht BN. An essential role for dendritic cells in human and experimental allergic rhinitis. J Allergy Clin Immunol 2006, 118(5):1117-1125. 10.1016/j.jaci.2006.05.030, 17088138.
29. Rossi GA, Sacco O, Cosulich E, Damiani G, Corte G, Bargellesi A, Ravazzoni C. Pulmonary sarcoidosis: excess of helper T lymphocytes and T cell subset imbalance at sites of disease activity. Thorax 1984, 39(2):143-149. 10.1136/thx.39.2.143, 459742, 6230751.
30. Hunninghake GW, Crystal RG. Pulmonary sarcoidosis: a disorder mediated by excess helper T-lymphocyte activity at sites of disease activity. New Eng J Med 1981, 305(8):429-434. 10.1056/NEJM198108203050804, 6454846.
31. Katchar K, Eklund A, Grunewald J. Expression of Th1 markers by lung accumulated T cells in pulmonary sarcoidosis. J Intern Med 2003, 254(6):564-571. 10.1111/j.1365-2796.2003.01230.x, 14641797.
32. Nishioka Y, Manabe K, Kishi J, Wang W, Inayama M, Azuma M, Sone S. CXCL9 and 11 in patients with pulmonary sarcoidosis: a role of alveolar macrophages. Clin Exp Immunol 2007, 149(2):317-326. 10.1111/j.1365-2249.2007.03423.x, 1941950, 17550373.
33. Masten BJ, Olson GK, Tarleton CA, Rund C, Schuyler M, Mehran R, Archibeque T, Lipscomb MF. Characterization of myeloid and plasmacytoid dendritic cells in human lung. J Immunol 2006, 177(11):7784-7793.
34. Scadding JG. Prognosis of intrathoracic sarcoidosis in England. A review of 136 cases after five years' observation. Brit Med J 1961, 2(5261):1165-1172. 10.1136/bmj.2.5261.1165, 1970202, 14497750.
35. Vermaelen K, Pauwels R. Pulmonary dendritic cells. Am J Respir Crit Care Med 2005, 172(5):530-551. 10.1164/rccm.200410-1384SO, 15879415.
36. Langenkamp A, Messi M, Lanzavecchia A, Sallusto F. Kinetics of dendritic cell activation: impact on priming of TH1, TH2 and nonpolarized T cells. Nat Immunol 2000, 1(4):311-316. 10.1038/79758, 11017102.
37. Holt PG, Oliver J, Bilyk N, McMenamin C, McMenamin PG, Kraal G, Thepen T. Downregulation of the antigen presenting cell function(s) of pulmonary dendritic cells in vivo by resident alveolar macrophages. J Exp Med 1993, 177(2):397-407. 10.1084/jem.177.2.397, 2190916, 8426110.
38. Facco M, Cabrelle A, Teramo A, Olivieri V, Gnoato M, Teolato S, Ave E, Gattazzo C, Fadini GP, Calabrese F, et al. Sarcoidosis is a Th1/Th17 multisystem disorder. Thorax 2011, 66(2):144-150. 10.1136/thx.2010.140319, 21139119.
39. Ten Berge B, Paats MS, Bergen IM, van den Blink B, Hoogsteden HC, Lambrecht BN, Hendriks RW, Kleinjan A. Increased IL-17A expression in granulomas and in circulating memory T cells in sarcoidosis. Rheumatology (Oxford) 2012, 51(1):37-46.
40. Sugiyama K, Mukae H, Ishii H, Kakugawa T, Ishimoto H, Nakayama S, Shirai R, Fujii T, Mizuta Y, Kohno S. Elevated levels of interferon gamma-inducible protein-10 and epithelial neutrophil-activating peptide-78 in patients with pulmonary sarcoidosis. Respirology 2006, 11(6):708-714. 10.1111/j.1440-1843.2006.00933.x, 17052298.
41. Wallis R, Ehlers S. Tumor necrosis factor and granuloma biology: explaining the differential infection risk of etanercept and infliximab. Sem Arthritis Rheum 2005, 34(5):34-38.
42. Medica I, Kastrin A, Maver A, Peterlin B. Role of genetic polymorphisms in ACE and TNF-alpha gene in sarcoidosis: a meta-analysis. J Hum Genet 2007, 52(10):836-847. 10.1007/s10038-007-0185-7, 17768594.
43. Wijnen PA, Nelemans PJ, Verschakelen JA, Bekers O, Voorter CE, Drent M. The role of tumor necrosis factor alpha G-308A polymorphisms in the course of pulmonary sarcoidosis. Tissue Antigens 2010, 75(3):262-268. 10.1111/j.1399-0039.2009.01437.x, 20070603.
44. Baughman RP, Lower EE, Drent M. Inhibitors of tumor necrosis factor (TNF) in sarcoidosis: who, what, and how to use them. Sarcoidosis Vasc Diffuse Lung Dis 2008, 25(2):76-89.