11,12,20-trihydroxy-eicosa-8(Z)-enoic acid: A selective inhibitor of 11,12-EET-induced relaxations of bovine coronary and rat mesenteric arteries

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 302, Issue 8, 2012, Pages

  Bukhari, Ishfaq A ^a   Shah, Abdul Jabbar ^a   Gauthier, Kathryn M ^a   Walsh, Katherine A ^a   Koduru, Sreenivasulu Reddy ^a   Imig, John D ^a   Falck, John R ^b   Campbell, William B ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Arteries; Endothelium derived hyperpolarizing factor; Epoxyeicosatrienoic acid; Soluble epoxide hydrolase; Vascular relaxation

Indexed keywords

11,12,20 TRIHYDROXY EICOSA 8 ENOIC ACID; 14,15 DIHYDROXY EICOSA 5 ENOIC ACID; 14,15 EPOXY 5,8,11 ICOSATRIENOIC ACID; 15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 20 HYDROXY 11,12 EPOXYEICOSA 8 ENOIC ACID; 5,6 EPOXY 8,11,14 ICOSATRIENOIC ACID; 8,9 EPOXYICOSATRIENOIC ACID; ARACHIDONIC ACID; EPOXYICOSATRIENOIC ACID; UNCLASSIFIED DRUG; VASODILATOR AGENT;

ANIMAL CELL; ARTERY BLOOD FLOW; ARTICLE; BLOOD VESSEL REACTIVITY; BLOOD VESSEL TONE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORONARY ARTERY DILATATION; DRUG ANTAGONISM; DRUG EFFECT; DRUG SYNTHESIS; FATTY ACID ANALYSIS; ICOSANOID METABOLISM; MALE; MESENTERIC ARTERY DILATATION; NONHUMAN; PRIORITY JOURNAL; RAT; STRUCTURE ACTIVITY RELATION; VASODILATATION;

8,11,14-EICOSATRIENOIC ACID; ANIMALS; ARACHIDONIC ACID; CATTLE; CORONARY CIRCULATION; CORONARY VESSELS; ISOMETRIC CONTRACTION; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MALE; MASS SPECTROMETRY; MEMBRANE POTENTIALS; MESENTERIC ARTERIES; MUSCLE RELAXATION; MUSCLE, SMOOTH, VASCULAR; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS; RATS; RATS, SPRAGUE-DAWLEY; VASODILATION;

EID: 84859739269     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.01122.2011     Document Type: Article

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