Geranylgeranylacetone suppresses noise-induced expression of proinflammatory cytokines in the cochlea

Auris Nasus Larynx

Volumn 39, Issue 3, 2012, Pages 270-274

  Nakamoto, Tetsuya ^a   Mikuriya, Takefumi ^a   Sugahara, Kazuma ^a   Hirose, Yoshinobu ^a   Hashimoto, Tomoko ^a   Shimogori, Hiroaki ^a   Takii, Ryosuke ^a   Nakai, Akira ^a   Yamashita, Hiroshi ^a  

^a YAMAGUCHI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Cochlea; Cytokines; Heat shock proteins; Inflammation; Inner ear damage; Noise exposure

Indexed keywords

HEAT SHOCK PROTEIN 70; HEAT SHOCK TRANSCRIPTION FACTOR 1; INTERLEUKIN 1BETA; INTERLEUKIN 6; TEPRENONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUDITORY THRESHOLD; COCHLEA; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DRUG MECHANISM; EAR PROTECTION; EVOKED BRAIN STEM AUDITORY RESPONSE; HEARING LOSS; INFLAMMATION; MALE; MOUSE; NOISE; NOISE INJURY; NONHUMAN; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; AUDITORY THRESHOLD; COCHLEA; CYTOKINES; DITERPENES; DNA-BINDING PROTEINS; EVOKED POTENTIALS, AUDITORY, BRAIN STEM; HEARING LOSS, NOISE-INDUCED; INFLAMMATION; INTERLEUKIN-1BETA; INTERLEUKIN-6; MALE; MICE; MICE, INBRED CBA; NOISE; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSCRIPTION FACTORS;

EID: 84859725456     PISSN: 03858146     EISSN: 18791476     Source Type: Journal    
DOI: 10.1016/j.anl.2011.06.001     Document Type: Article

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