Improvement of porcine islet isolation by inhibition of trypsin activity during pancreas preservation and digestion using α1-antitrypsin

Cell Transplantation

Volumn 21, Issue 2-3, 2012, Pages 465-471

  Shimoda, Masayuki ^a   Noguchi, Hirofumi ^b   Fujita, Yasutaka ^c   Takita, Morihito ^b   Ikemoto, Tetsuya ^b   Chujo, Daisuke ^d   Naziruddin, Bashoo ^e   Levy, Marlon F ^b,e   Kobayashi, Naoya ^f   Grayburn, Paul A ^a   Matsumoto, Shinichi ^b  

^a BAYLOR UNIVERSITY MEDICAL CENTER   (United States)

^b BAYLOR RESEARCH INSTITUTE   (United States)

^c OTSUKA PHARMACEUTICAL CO LTD   (Japan)

^d BAYLOR INSTITUTE FOR IMMUNOLOGY RESEARCH   (United States)

^e Baylor Simmons Transplant Institute   (United States)

^f OKAYAMA UNIVERSITY   (Japan)

Author keywords

1 Antitrypsin; Islet transplantation; Porcine islets; Trypsin inhibitor; Xenotransplantation

Indexed keywords

ALPHA 1 ANTITRYPSIN; GLUCOSE; TRYPSIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ENZYME ACTIVITY; GLUCOSE BLOOD LEVEL; IN VITRO STUDY; IN VIVO STUDY; ISOLATED PANCREAS ISLET; ISOLATION PROCEDURE; MOUSE; NONHUMAN; ORGAN PRESERVATION; ORGAN WEIGHT; PANCREAS; PORCINE PANCREAS ISLET ISOLATION; PRIORITY JOURNAL; PURIFICATION; SWINE; XENOTRANSPLANTATION;

ALPHA 1-ANTITRYPSIN; ANIMALS; CELL SEPARATION; COLLAGENASES; FEMALE; HUMANS; ISLETS OF LANGERHANS; SWINE; TRYPSIN; TRYPSIN INHIBITORS;

SUS;

EID: 84859723786     PISSN: 09636897     EISSN: None     Source Type: Journal    
DOI: 10.3727/096368911X605376     Document Type: Article

References (29)

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