Improved Islet Yields After Purification Following the Novel Endogenous Trypsin Inhibitor and Histidine-Tryptophan-Ketoglutarate Treatment in Pigs

Transplantation Proceedings

Volumn 40, Issue 8, 2008, Pages 2585-2587

  Wee, Y M ^b   Kim, S C ^a   Koo, S K ^b   Kim, Y H ^b   Jung, E J ^b   Choi, M Y ^b   Park, Y H ^b   Park, K T ^a   Lim, D G ^b   Han, D J ^b  

^a University of Ulsan College of Medicine   (South Korea)

^b Asan Institute for Life Sciences   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

2 OXOGLUTARIC ACID; HISTIDINE; TRYPSIN INHIBITOR; TRYPTOPHAN; ULINASTATIN;

ANIMAL CELL; ARTICLE; CELL ISOLATION; CELL VIABILITY; ISOLATION AND PURIFICATION; NONHUMAN; PANCREAS ISLET CELL; PANCREAS PERFUSION; PRIORITY JOURNAL; PURIFICATION; SOLUTION AND SOLUBILITY; SWINE;

ANIMALS; CELL SEPARATION; GLUCOSE; HYPERTONIC SOLUTIONS; INSULIN; ISLETS OF LANGERHANS; MANNITOL; POTASSIUM CHLORIDE; PROCAINE; SWINE; TRYPSIN INHIBITORS;

EID: 53149102050     PISSN: 00411345     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.transproceed.2008.08.020     Document Type: Article

References (4)

1. Kim S.C., Han D.J., Kang C.H., et al. Experimental islet isolation in porcine pancreas with new enzyme Liberase PI. Transplant Proc 36 (2004) 2197
2. Bottino R., Balamurugan A.N., Smetanka C., et al. Isolation outcome and functional characteristics of young and adult pig pancreatic islets for transplantation studies. Xenotransplantation 14 (2007) 74
3. Rood P.P., Buhler L.H., Bottino R., et al. Pig-to-nonhuman primate islet xenotransplantation: a review of current problems. Cell Transplant 15 (2006) 89
4. Rose N.L., Palcic M.M., Helms L.M., et al. Evaluation of Pefabloc as a serine protease inhibitor during human-islet isolation. Transplantation 75 (2003) 462