-
1
-
-
2342595765
-
Trends in antimicrobial drug development: Implications for the future
-
DOI 10.1086/420937
-
Spellberg B, Powers J, Brass E, Miller L, Edwards J. Trends in antimicrobial drug development: implications for the future. Clin Infect Dis 2004;38:1279-86. (Pubitemid 38608571)
-
(2004)
Clinical Infectious Diseases
, vol.38
, Issue.9
, pp. 1279-1286
-
-
Spellberg, B.1
Powers, J.H.2
Brass, E.P.3
Miller, L.G.4
Edwards Jr., J.E.5
-
2
-
-
0005914572
-
The bacterial challenge: Time to react
-
Aronsson B, Boscan IS, Cars O, Giamarellou H, Gyssens IC, Lutsar I, et al. The bacterial challenge: time to react. European Centre for Disease Prevention and Control and European Medicines Agency joint report. 2009 www.ema.europa.eu/pdfs/human/antimicrobial-resistance/EMEA-576176-2009.pdf
-
(2009)
European Centre for Disease Prevention and Control and European Medicines Agency Joint Report
-
-
Aronsson, B.1
Boscan, I.S.2
Cars, O.3
Giamarellou, H.4
Gyssens, I.C.5
Lutsar, I.6
-
4
-
-
0242291985
-
Why is big Pharma getting out of antibacterial drug discovery?
-
DOI 10.1016/j.mib.2003.08.003
-
Projan SJ. Why is big pharma getting out of antibacterial drug discovery? Curr Opin Microbiol 2003;6:427-30. (Pubitemid 37345405)
-
(2003)
Current Opinion in Microbiology
, vol.6
, Issue.5
, pp. 427-430
-
-
Projan, S.J.1
-
5
-
-
77950190104
-
-
Final report
-
Mossialos E, Morel C, Edwards S, Berenson J, Gemmill-Toyama M, Brogan D. Policies and incentives to promote innovation in antibiotic research. Final report 2010. www.euro.who.int/--data/assets/pdf-file/0011/120143/E94241.
-
(2010)
Policies and Incentives to Promote Innovation in Antibiotic Research
-
-
Mossialos, E.1
Morel, C.2
Edwards, S.3
Berenson, J.4
Gemmill-Toyama, M.5
Brogan, D.6
-
6
-
-
78649695936
-
Fighting antibiotic resistance: Marrying new financial incentives to meeting public health goals
-
Kesselheim A, Outterson K. Fighting antibiotic resistance: marrying new financial incentives to meeting public health goals. Health Aff 2010;29:1689.
-
(2010)
Health Aff
, vol.29
, pp. 1689
-
-
Kesselheim, A.1
Outterson, K.2
-
7
-
-
33845903833
-
Drugs for bad bugs: Confronting the challenges of antibacterial discovery
-
DOI 10.1038/nrd2201, PII NRD2201
-
Payne D, Gwynn M, Holmes D, Pompliano D. Drugs for bad bugs: confronting the challenges of antibacterial discovery. Nature Rev Drug Discovery 2007;6:29-40. (Pubitemid 46020284)
-
(2007)
Nature Reviews Drug Discovery
, vol.6
, Issue.1
, pp. 29-40
-
-
Payne, D.J.1
Gwynn, M.N.2
Holmes, D.J.3
Pompliano, D.L.4
-
8
-
-
4444295503
-
Seeing is believing: The impact of structural genomics on antimicrobial drug discovery
-
Schmid M. Seeing is believing: the impact of structural genomics on antimicrobial drug discovery. Nature 2004;2:239.
-
(2004)
Nature
, vol.2
, pp. 239
-
-
Schmid, M.1
-
9
-
-
84873065960
-
Collaboration for innovation - The urgent need for new antibiotics
-
ReAct. Collaboration for innovation - the urgent need for new antibiotics. ReAct policy seminar, 23 May 2011, Brussels, Belgium. www.reactgroup.org/uploads/news/Collaboration-for-Innovation-The-Urgent-Need- for-New-Antibiotics-ReAct-Policy-Seminar-Brussels-May-23-2011.pdf.
-
ReAct Policy Seminar, 23 May 2011, Brussels, Belgium
-
-
-
12
-
-
70449640250
-
Advancing drug innovation for neglected diseases - Criteria for lead progression
-
Nwaka S, Ramirez B, Brun R, Maes L, Douglas F, Ridley R. Advancing drug innovation for neglected diseases - criteria for lead progression. PLoS Negl Trop Dis 2009;8:e440.
-
(2009)
PLoS Negl Trop Dis
, vol.8
-
-
Nwaka, S.1
Ramirez, B.2
Brun, R.3
Maes, L.4
Douglas, F.5
Ridley, R.6
-
13
-
-
46749083039
-
Pathways across the valley of death: Novel intellectual property strategies for accelerated drug discovery
-
Rai AK, Reichman JH, Uhlir PF, Crossman C. Pathways across the valley of death: novel intellectual property strategies for accelerated drug discovery. Yale J Health Law, Policy, Ethics 2008;8:53-89.
-
(2008)
Yale J Health Law, Policy, Ethics
, vol.8
, pp. 53-89
-
-
Rai, A.K.1
Reichman, J.H.2
Uhlir, P.F.3
Crossman, C.4
-
16
-
-
79960100831
-
Reengineering translational science: The time is right
-
Collins F. Reengineering translational science: the time is right. Science Transl Med 2011;3:90:90cm17. www.nih.gov/about/director/articles/ translational-science-07062011.pdf.
-
(2011)
Science Transl Med
, vol.3
, Issue.90
-
-
Collins, F.1
-
17
-
-
41349114440
-
The cystic fibrosis foundation therapeutics development network: A national effort by the cystic fibrosis foundation to build a clinical trials network
-
DOI 10.1080/02739610701766859, PII 790613577
-
Goss C, Mayer-Hamblett N. The Cystic Fibrosis Foundation therapeutics development network: a national effort by the Cystic Fibrosis Foundation to build a clinical trials network. Children's Health Care 2008;37:5-20. (Pubitemid 351451040)
-
(2008)
Children's Health Care
, vol.37
, Issue.1
, pp. 5-20
-
-
Goss, C.H.1
Mayer-Hamblett, N.2
Williams, J.3
Ramsey, B.W.4
-
19
-
-
77955037813
-
Developing ANDI: A novel approach to health product R&D in Africa
-
Nwaka S, Ilunga T, Da Silva J, Verde E, Hackley D, Vre R, et al. Developing ANDI: a novel approach to health product R&D in Africa. PLoS Medicine 2010;7:e1000293.
-
(2010)
PLoS Medicine
, vol.7
-
-
Nwaka, S.1
Ilunga, T.2
Da Silva, J.3
Verde, E.4
Hackley, D.5
Vre, R.6
-
21
-
-
84873063323
-
Trius receives $29.5 million contract to find microbe antibiotics
-
Sep 20
-
Fikes B. Trius receives $29.5 million contract to find microbe antibiotics. North County Times 2010 Sep 20. www.nctimes.com/business/article- bb6141ed-f20b-5016-b00e-96a2bacab749.html.
-
(2010)
North County Times
-
-
Fikes, B.1
-
22
-
-
84873070967
-
-
http:///US Department of Health & Human Services. Press release, 30 August
-
http:///US Department of Health & Human Services. BARDA funds drug development for biothreats, antibiotic resistance. Press release, 30 August 2010. www.hhs.gov/news/press/2010pres/08/20100830a.html.
-
(2010)
BARDA Funds Drug Development for Biothreats, Antibiotic Resistance
-
-
-
23
-
-
84873061614
-
-
Wellcome Trust. Therapeutics. 2010. www.wellcome.ac.uk/Funding/ Technology-transfer/Funded-projects/therapeutics/index.htm.
-
(2010)
Therapeutics
-
-
-
24
-
-
84873072607
-
-
Innovative Medicines Initiative. NewDrugs4BadBugs (ND4BB). www.imi.europa.eu/content/future-topics.
-
NewDrugs4BadBugs (ND4BB)
-
-
-
25
-
-
4344623391
-
R&D costs and returns by therapeutic category
-
DiMasi J, Grabowski H, Vernon J. R&D costs and returns by therapeutic category. Drug Info J 2004;38:211-23.
-
(2004)
Drug Info J
, vol.38
, pp. 211-223
-
-
DiMasi, J.1
Grabowski, H.2
Vernon, J.3
-
31
-
-
78649695936
-
Fighting antibiotic resistance: Marrying new financial incentives to meeting public health goals
-
Kesselheim A, Outterson K. Fighting antibiotic resistance: marrying new financial incentives to meeting public health goals. Health Aff 2010;29:1689.
-
(2010)
Health Aff
, vol.29
, pp. 1689
-
-
Kesselheim, A.1
Outterson, K.2
-
33
-
-
79955770863
-
The role of the pharmaceutical industry in meeting the public health threat of antibacterial resistance
-
Bergström R. The role of the pharmaceutical industry in meeting the public health threat of antibacterial resistance. Drug Resist Updates 2010;14:77-8.
-
(2010)
Drug Resist Updates
, vol.14
, pp. 77-78
-
-
Bergström, R.1
|