-
1
-
-
78049485263
-
Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
-
Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer 2010; 127: 2893-917.
-
(2010)
Int J Cancer
, vol.127
, pp. 2893-2917
-
-
Ferlay, J.1
Shin, H.R.2
Bray, F.3
Forman, D.4
Mathers, C.5
Parkin, D.M.6
-
2
-
-
77954346705
-
on behalf of the ESMO Guidelines Working Group. Advanced colorectal cancer: ESMO clinical practice guidelines for treatment
-
Van Cutsem E, Nordlinger B, Cervantes A; on behalf of the ESMO Guidelines Working Group. Advanced colorectal cancer: ESMO clinical practice guidelines for treatment. Ann Oncol 2010; 21(Suppl 5): v93-7.
-
(2010)
Ann Oncol
, vol.21
, Issue.SUPPL. 5
-
-
Van Cutsem, E.1
Nordlinger, B.2
Cervantes, A.3
-
3
-
-
77955635233
-
Cancer Statistics, 2010
-
Jemal A, Siegel R, Xu J, Ward E. Cancer Statistics, 2010. CA-Cancer J Clin 2010; 60: 277-300.
-
(2010)
CA-Cancer J Clin
, vol.60
, pp. 277-300
-
-
Jemal, A.1
Siegel, R.2
Xu, J.3
Ward, E.4
-
5
-
-
77649183418
-
Cetuximab-based therapy versus noncetuximab therapy for advanced cancer: a meta-analysis of 17 randomized controlled trials
-
Liu L, Cao Y, Tan A, Liao C, Gao F. Cetuximab-based therapy versus noncetuximab therapy for advanced cancer: a meta-analysis of 17 randomized controlled trials. Cancer Chemoth Pharm 2010; 65: 849-61.
-
(2010)
Cancer Chemoth Pharm
, vol.65
, pp. 849-861
-
-
Liu, L.1
Cao, Y.2
Tan, A.3
Liao, C.4
Gao, F.5
-
6
-
-
40849147041
-
EGFR antagonists in cancer treatment
-
Ciardiello F, Tortora G. EGFR antagonists in cancer treatment. N Engl J Med 2008; 358: 1160-74.
-
(2008)
N Engl J Med
, vol.358
, pp. 1160-1174
-
-
Ciardiello, F.1
Tortora, G.2
-
7
-
-
3242720345
-
Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer
-
Cunningham D, Humblet Y, Siena S et al. Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer. N Engl J Med 2004; 351: 337-45.
-
(2004)
N Engl J Med
, vol.351
, pp. 337-345
-
-
Cunningham, D.1
Humblet, Y.2
Siena, S.3
-
8
-
-
19944426509
-
Impact of EGFR expression on colorectal cancer patient prognosis and survival
-
Spano JP, Lagorce C, Atlan D et al. Impact of EGFR expression on colorectal cancer patient prognosis and survival. Ann Oncol 2005; 16: 102-8.
-
(2005)
Ann Oncol
, vol.16
, pp. 102-108
-
-
Spano, J.P.1
Lagorce, C.2
Atlan, D.3
-
9
-
-
20144381957
-
Cetuximab shows activity in colorectal cancer patients with tumors that do not express the epidermal growth factor receptor by immunohistochemistry
-
Chung KY, Shia J, Kemeny NE et al. Cetuximab shows activity in colorectal cancer patients with tumors that do not express the epidermal growth factor receptor by immunohistochemistry. J Clin Oncol 2005; 23: 1803-10.
-
(2005)
J Clin Oncol
, vol.23
, pp. 1803-1810
-
-
Chung, K.Y.1
Shia, J.2
Kemeny, N.E.3
-
10
-
-
40649125816
-
Cetuximab shows activity in colorectal cancer patients with tumors for which FISH analysis does not detect an increase in EGFR gene copy number
-
Italiano A, Follana P, Caroli FX et al. Cetuximab shows activity in colorectal cancer patients with tumors for which FISH analysis does not detect an increase in EGFR gene copy number. Ann Surg Oncol 2008; 15: 649-54.
-
(2008)
Ann Surg Oncol
, vol.15
, pp. 649-654
-
-
Italiano, A.1
Follana, P.2
Caroli, F.X.3
-
11
-
-
33750615769
-
Multicenter phase II and translational study of cetuximab in metastatic colorectal carcinoma refractory to irinotecan, oxaliplatin, and fluoropyrimidines
-
Lenz HJ, Van Cutsem E, Khambata-Ford S et al. Multicenter phase II and translational study of cetuximab in metastatic colorectal carcinoma refractory to irinotecan, oxaliplatin, and fluoropyrimidines. J Clin Oncol 2006; 24: 4914-21.
-
(2006)
J Clin Oncol
, vol.24
, pp. 4914-4921
-
-
Lenz, H.J.1
Van Cutsem, E.2
Khambata-Ford, S.3
-
12
-
-
77958023788
-
Colorectal cancer: cetuximab, KRAS, BRAF, PIK3CA mutations and beyond
-
Katsios C, Ziogas DE, Roukos DH. Colorectal cancer: cetuximab, KRAS, BRAF, PIK3CA mutations and beyond. Expert Rev Gastroenterol Hepatol 2010; 4: 525-9.
-
(2010)
Expert Rev Gastroenterol Hepatol
, vol.4
, pp. 525-529
-
-
Katsios, C.1
Ziogas, D.E.2
Roukos, D.H.3
-
13
-
-
63849088630
-
Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer
-
Van Cutsem E, Kohne C, Hitre E et al. Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer. N Engl J Med 2009; 360: 1408-17.
-
(2009)
N Engl J Med
, vol.360
, pp. 1408-1417
-
-
Van Cutsem, E.1
Kohne, C.2
Hitre, E.3
-
14
-
-
77953216750
-
Oncogenic KRAS desensitizes colorectal tumor cells to epidermal growth factor receptor inhibition and activation
-
van Houdt WJ, Hoogwater FJ, de Bruijn MT et al. Oncogenic KRAS desensitizes colorectal tumor cells to epidermal growth factor receptor inhibition and activation. Neoplasia 2010; 12: 443-52.
-
(2010)
Neoplasia
, vol.12
, pp. 443-452
-
-
van Houdt, W.J.1
Hoogwater, F.J.2
de Bruijn, M.T.3
-
15
-
-
79551580551
-
Systematic review: antiepidermal growth factor receptor treatment effect modification by KRAS mutations in advanced colorectal cancer
-
Dahabreh IJ, Terasawa T, Castaldi PJ, Trikalinos TA. Systematic review: antiepidermal growth factor receptor treatment effect modification by KRAS mutations in advanced colorectal cancer. Ann Intern Med 2011; 154: 37-49.
-
(2011)
Ann Intern Med
, vol.154
, pp. 37-49
-
-
Dahabreh, I.J.1
Terasawa, T.2
Castaldi, P.J.3
Trikalinos, T.A.4
-
16
-
-
77953184059
-
Practical and molecular evaluation of colorectal cancer: new roles for the pathologist in the era of targeted therapy
-
De Hertogh G, Geboes KP. Practical and molecular evaluation of colorectal cancer: new roles for the pathologist in the era of targeted therapy. Arch Pathol Lab Med 2010; 134: 853-63.
-
(2010)
Arch Pathol Lab Med
, vol.134
, pp. 853-863
-
-
De Hertogh, G.1
Geboes, K.P.2
-
17
-
-
77950853766
-
Epidermal growth factor receptor gene copy number in 101 advanced colorectal cancer patients treated with chemotherapy plus cetuximab
-
Campanella C, Mottolese M, Cianciulli A et al. Epidermal growth factor receptor gene copy number in 101 advanced colorectal cancer patients treated with chemotherapy plus cetuximab. J Transl Med 2010; 8: 36.
-
(2010)
J Transl Med
, vol.8
, pp. 36
-
-
Campanella, C.1
Mottolese, M.2
Cianciulli, A.3
-
18
-
-
67650085299
-
PET of EGFR antibody distribution in head and neck squamous cell carcinoma models
-
Niu G, Li Z, Xie J, Le QT, Chen X. PET of EGFR antibody distribution in head and neck squamous cell carcinoma models. J Nucl Med 2009; 50: 1116-23.
-
(2009)
J Nucl Med
, vol.50
, pp. 1116-1123
-
-
Niu, G.1
Li, Z.2
Xie, J.3
Le, Q.T.4
Chen, X.5
-
19
-
-
58149392589
-
Imaging of EGFR and EGFR tyrosine kinase overexpression in tumors by nuclear medicine modalities
-
Mishani E, Abourbeh G, Eiblmaier M, Anderson CJ. Imaging of EGFR and EGFR tyrosine kinase overexpression in tumors by nuclear medicine modalities. Curr Pharm Des 2008; 14: 2983-98.
-
(2008)
Curr Pharm Des
, vol.14
, pp. 2983-2998
-
-
Mishani, E.1
Abourbeh, G.2
Eiblmaier, M.3
Anderson, C.J.4
-
20
-
-
34249055896
-
64Cu-labeled cetuximab, a chimeric anti-EGFR monoclonal antibody
-
64Cu-labeled cetuximab, a chimeric anti-EGFR monoclonal antibody. Eur J Nucl Med Mol I 2007; 34: 850-8.
-
(2007)
Eur J Nucl Med Mol I
, vol.34
, pp. 850-858
-
-
Cai, W.1
Chen, K.2
He, L.3
Cao, Q.4
Koong, A.5
Chen, X.6
-
21
-
-
33644827799
-
177Lu in tumor-bearing nude mice after coupling to the internalizing antibody cetuximab
-
177Lu in tumor-bearing nude mice after coupling to the internalizing antibody cetuximab. J Nucl Med 2005; 46: 1898-906.
-
(2005)
J Nucl Med
, vol.46
, pp. 1898-1906
-
-
Perk, L.R.1
Visser, G.W.M.2
Vosjan, M.J.W.D.3
-
23
-
-
55849141650
-
Cetuximab: preclinical evaluation of a monoclonal antibody targeting EGFR for radioimmunodiagnostic and radioimmunotherapeutic applications
-
Milenic DE, Wong KJ, Baidoo KE et al. Cetuximab: preclinical evaluation of a monoclonal antibody targeting EGFR for radioimmunodiagnostic and radioimmunotherapeutic applications. Cancer Biother Radiopharm 2008; 23: 619-32.
-
(2008)
Cancer Biother Radiopharm
, vol.23
, pp. 619-632
-
-
Milenic, D.E.1
Wong, K.J.2
Baidoo, K.E.3
-
27
-
-
0024429864
-
Signal transduction by epidermal growth factor occurs through the subclass of high affinity receptors
-
Defize LH, Boonstra J, Meisenhelder J et al. Signal transduction by epidermal growth factor occurs through the subclass of high affinity receptors. J Cell Biol 1989; 109: 2495-507.
-
(1989)
J Cell Biol
, vol.109
, pp. 2495-2507
-
-
Defize, L.H.1
Boonstra, J.2
Meisenhelder, J.3
-
28
-
-
67651124762
-
Molecular imaging of cancer with copper-64 radiopharmaceuticals and positron emission tomography (PET)
-
Shokeen M, Anderson CJ. Molecular imaging of cancer with copper-64 radiopharmaceuticals and positron emission tomography (PET). Acc Chem Res 2009; 42: 832-41.
-
(2009)
Acc Chem Res
, vol.42
, pp. 832-841
-
-
Shokeen, M.1
Anderson, C.J.2
-
31
-
-
84874105587
-
64Cu-labeled chimeric anti-EGFR monoclonal antibody cetuximab for PET imaging of prostate cancer
-
64Cu-labeled chimeric anti-EGFR monoclonal antibody cetuximab for PET imaging of prostate cancer. J Nucl Med 2006; 47(Suppl 1): 107P.
-
(2006)
J Nucl Med
, vol.47
, Issue.SUPPL. 1
-
-
Cai, W.1
Cao, Q.2
Chen, K.3
Zhang, X.4
Chen, X.5
-
33
-
-
77349101832
-
Usefulness of peptide nucleic acid (PNA)-Clamp smart amplification process version 2 (SmartAmp2) for clinical diagnosis of KRAS Codon12 mutations in lung adenocarcinoma: comparison of PNA-Clamp SmartAmp2 and PCR-related methods
-
Araki T, Shimizu K, Nakamura K et al. Usefulness of peptide nucleic acid (PNA)-Clamp smart amplification process version 2 (SmartAmp2) for clinical diagnosis of KRAS Codon12 mutations in lung adenocarcinoma: comparison of PNA-Clamp SmartAmp2 and PCR-related methods. J Mol Diagn 2010; 12: 118-24.
-
(2010)
J Mol Diagn
, vol.12
, pp. 118-124
-
-
Araki, T.1
Shimizu, K.2
Nakamura, K.3
-
34
-
-
84874111195
-
COSMIC Database, Sanger Institute
-
Distribution of somatic mutations in KRAS
-
Distribution of somatic mutations in KRAS. COSMIC Database, Sanger Institute. [Cited 21 Feb 2011.] Available from URL: http://www.sanger.ac.uk/perl/genetics/CGP/cosmic?action=bygene&ln=KRAS.
-
[Cited 21 Feb 2011.] Available from
-
-
-
35
-
-
75149133723
-
In vivo molecular imaging of colorectal cancer with confocal endomicroscopy by targeting epidermal growth factor receptor
-
Goetz M, Ziebart A, Foersch S et al. In vivo molecular imaging of colorectal cancer with confocal endomicroscopy by targeting epidermal growth factor receptor. Gastroenterology 2010; 138: 435-46.
-
(2010)
Gastroenterology
, vol.138
, pp. 435-446
-
-
Goetz, M.1
Ziebart, A.2
Foersch, S.3
-
36
-
-
58149352912
-
Molecular imaging of therapeutic response to epidermal growth factor receptor blockade in colorectal cancer
-
Manning HC, Merchant NB, Foutch AC et al. Molecular imaging of therapeutic response to epidermal growth factor receptor blockade in colorectal cancer. Clin Cancer Res 2008; 14: 7413-22.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 7413-7422
-
-
Manning, H.C.1
Merchant, N.B.2
Foutch, A.C.3
-
37
-
-
33947420511
-
Antibody-dependent cellular cytotoxicity mediated by cetuximab against lung cancer cell lines
-
Kurai J, Chikumi H, Hashimoto K et al. Antibody-dependent cellular cytotoxicity mediated by cetuximab against lung cancer cell lines. Clin Cancer Res 2007; 13: 1552-61.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 1552-1561
-
-
Kurai, J.1
Chikumi, H.2
Hashimoto, K.3
-
38
-
-
0028786707
-
RadioimmunoPET: detection of colorectal carcinoma with positron-emitting copper-64-labeled monoclonal antibody
-
Philpott GW, Schwarz SW, Anderson CJ et al. RadioimmunoPET: detection of colorectal carcinoma with positron-emitting copper-64-labeled monoclonal antibody. J Nucl Med 1995; 36: 1818-24.
-
(1995)
J Nucl Med
, vol.36
, pp. 1818-1824
-
-
Philpott, G.W.1
Schwarz, S.W.2
Anderson, C.J.3
-
39
-
-
70350736124
-
89Zrlabeled chimeric monoclonal antibody U36 as used for immuno-PET in head and neck cancer patients
-
89Zrlabeled chimeric monoclonal antibody U36 as used for immuno-PET in head and neck cancer patients. J Nucl Med 2009; 50: 1828-36.
-
(2009)
J Nucl Med
, vol.50
, pp. 1828-1836
-
-
Borjesson, P.K.E.1
Jauw, Y.W.S.2
de Bree, R.3
|