-
1
-
-
67650874081
-
Cancer statistics, 2009
-
[PMID: 19474385]
-
Jemal A, Siegel R, Ward E, Hao Y, Xu J, Thun MJ. Cancer statistics, 2009. CA Cancer J Clin. 2009;59:225-49. [PMID: 19474385]
-
(2009)
CA Cancer J Clin
, vol.59
, pp. 225-249
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Hao, Y.4
Xu, J.5
Thun, M.J.6
-
2
-
-
55049134360
-
Chemotherapy for colorectal cancer liver metasta-ses
-
[PMID: 18838438]
-
Alberts SR, Wagman LD. Chemotherapy for colorectal cancer liver metasta-ses. Oncologist. 2008;13:1063-73. [PMID: 18838438]
-
(2008)
Oncologist
, vol.13
, pp. 1063-1073
-
-
Alberts, S.R.1
Wagman, L.D.2
-
3
-
-
77949437015
-
Colorectal cancer
-
[PMID: 20304247]
-
Cunningham D, Atkin W, Lenz HJ, Lynch HT, Minsky B, Nordlinger B, et al. Colorectal cancer. Lancet. 2010;375:1030-47. [PMID: 20304247]
-
(2010)
Lancet
, vol.375
, pp. 1030-1047
-
-
Cunningham, D.1
Atkin, W.2
Lenz, H.J.3
Lynch, H.T.4
Minsky, B.5
Nordlinger, B.6
-
4
-
-
0037025173
-
Cancer. Addiction to oncogenes-the Achilles heal of cancer
-
[PMID: 12098689]
-
Weinstein IB. Cancer. Addiction to oncogenes-the Achilles heal of cancer. Science. 2002;297:63-4. [PMID: 12098689]
-
(2002)
Science
, vol.297
, pp. 63-64
-
-
Weinstein, I.B.1
-
5
-
-
77956103532
-
A review of the most promising biomarkers in colorectal cancer: One step closer to targeted therapy
-
[PMID: 20584808]
-
Deschoolmeester V, Baay M, Specenier P, Lardon F, Vermorken JB. A review of the most promising biomarkers in colorectal cancer: one step closer to targeted therapy. Oncologist. 2010;15:699-731. [PMID: 20584808]
-
(2010)
Oncologist
, vol.15
, pp. 699-731
-
-
Deschoolmeester, V.1
Baay, M.2
Specenier, P.3
Lardon, F.4
Vermorken, J.B.5
-
6
-
-
0036362181
-
Why the epidermal growth factor receptor? The rationale for cancer therapy
-
[PMID: 12202782]
-
Baselga J. Why the epidermal growth factor receptor? The rationale for cancer therapy. Oncologist. 2002;7 Suppl 4:2-8. [PMID: 12202782]
-
(2002)
Oncologist
, vol.7
, Issue.4 SUPPL
, pp. 2-8
-
-
Baselga, J.1
-
7
-
-
2342591455
-
The discovery of receptor tyrosine kinases: Targets for cancer therapy
-
[PMID: 15122207]
-
Gschwind A, Fischer OM, Ullrich A. The discovery of receptor tyrosine kinases: targets for cancer therapy. Nat Rev Cancer. 2004;4:361-70. [PMID: 15122207]
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 361-370
-
-
Gschwind, A.1
Fischer, O.M.2
Ullrich, A.3
-
8
-
-
19944426509
-
Impact of EGFR expression on colorectal cancer patient prognosis and survival
-
[PMID: 15598946]
-
Spano JP, Lagorce C, Atlan D, Milano G, Domont J, Benamouzig R, et al. Impact of EGFR expression on colorectal cancer patient prognosis and survival. Ann Oncol. 2005;16:102-8. [PMID: 15598946]
-
(2005)
Ann Oncol
, vol.16
, pp. 102-108
-
-
Spano, J.P.1
Lagorce, C.2
Atlan, D.3
Milano, G.4
Domont, J.5
Benamouzig, R.6
-
9
-
-
77649179941
-
Epidermal growth factor receptor (EGFR) mRNA levels and protein expression levels in primary colorectal cancer and corresponding liver metastases
-
[PMID: 19701635]
-
Kuramochi H, Hayashi K, Nakajima G, Kamikozuru H, Yamamoto M, Danenberg KD, et al. Epidermal growth factor receptor (EGFR) mRNA levels and protein expression levels in primary colorectal cancer and corresponding liver metastases. Cancer Chemother Pharmacol. 2010;65:825-31. [PMID: 19701635]
-
(2010)
Cancer Chemother Pharmacol
, vol.65
, pp. 825-831
-
-
Kuramochi, H.1
Hayashi, K.2
Nakajima, G.3
Kamikozuru, H.4
Yamamoto, M.5
Danenberg, K.D.6
-
10
-
-
36148941301
-
Cetuximab for the treatment of colorectal cancer
-
[PMID: 18003960]
-
Jonker DJ, O'Callaghan CJ, Karapetis CS, Zalcberg JR, Tu D, Au HJ, et al. Cetuximab for the treatment of colorectal cancer. N Engl J Med. 2007;357: 2040-8. [PMID: 18003960]
-
(2007)
N Engl J Med
, vol.357
, pp. 2040-2048
-
-
Jonker, D.J.1
O'Callaghan, C.J.2
Karapetis, C.S.3
Zalcberg, J.R.4
Tu, D.5
Au, H.J.6
-
11
-
-
34147103678
-
Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy-refractory meta-static colorectal cancer
-
[PMID: 17470858]
-
Van Cutsem E, Peeters M, Siena S, Humblet Y, Hendlisz A, Neyns B, et al. Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy-refractory meta-static colorectal cancer. J Clin Oncol. 2007;25:1658-64. [PMID: 17470858]
-
(2007)
J Clin Oncol
, vol.25
, pp. 1658-1664
-
-
van Cutsem, E.1
Peeters, M.2
Siena, S.3
Humblet, Y.4
Hendlisz, A.5
Neyns, B.6
-
12
-
-
0024376173
-
Ras oncogenes in human cancer: A review
-
[PMID: 2547513]
-
Bos JL. Ras oncogenes in human cancer: a review. Cancer Res. 1989;49: 4682-9. [PMID: 2547513]
-
(1989)
Cancer Res
, vol.49
, pp. 4682-4689
-
-
Bos, J.L.1
-
13
-
-
70349939382
-
Bi-omarkers predicting clinical outcome of epidermal growth factor receptor-targeted therapy in metastatic colorectal cancer
-
[PMID: 19738166]
-
Siena S, Sartore-Bianchi A, Di Nicolantonio F, Balfour J, Bardelli A. Bi-omarkers predicting clinical outcome of epidermal growth factor receptor-targeted therapy in metastatic colorectal cancer. J Natl Cancer Inst. 2009;101: 1308-24. [PMID: 19738166]
-
(2009)
J Natl Cancer Inst
, vol.101
, pp. 1308-1324
-
-
Siena, S.1
Sartore-Bianchi, A.2
Di Nicolantonio, F.3
Balfour, J.4
Bardelli, A.5
-
14
-
-
42649145667
-
Wild-type KRAS is required for panitumumab efficacy in patients with met-astatic colorectal cancer
-
[PMID: 18316791]
-
Amado RG, Wolf M, Peeters M, Van Cutsem E, Siena S, Freeman DJ, et al. Wild-type KRAS is required for panitumumab efficacy in patients with met-astatic colorectal cancer. J Clin Oncol. 2008;26:1626-34. [PMID: 18316791]
-
(2008)
J Clin Oncol
, vol.26
, pp. 1626-1634
-
-
Amado, R.G.1
Wolf, M.2
Peeters, M.3
van Cutsem, E.4
Siena, S.5
Freeman, D.J.6
-
15
-
-
54949085398
-
K-ras mutations and benefit from cetuximab in advanced colo-rectal cancer
-
[PMID: 18946061]
-
Karapetis CS, Khambata-Ford S, Jonker DJ, O'Callaghan CJ, Tu D, Teb-butt NC, et al. K-ras mutations and benefit from cetuximab in advanced colo-rectal cancer. N Engl J Med. 2008;359:1757-65. [PMID: 18946061]
-
(2008)
N Engl J Med
, vol.359
, pp. 1757-1765
-
-
Karapetis, C.S.1
Khambata-Ford, S.2
Jonker, D.J.3
O'Callaghan, C.J.4
Tu, D.5
Teb-Butt, N.C.6
-
16
-
-
63849088630
-
Cetuximab and chemotherapy as initial treatment for metastatic colo-rectal cancer
-
[PMID: 19339720]
-
Van Cutsem E, Köhne CH, Hitre E, Zaluski J, Chang Chien CR, Makhson A, et al. Cetuximab and chemotherapy as initial treatment for metastatic colo-rectal cancer. N Engl J Med. 2009;360:1408-17. [PMID: 19339720]
-
(2009)
N Engl J Med
, vol.360
, pp. 1408-1417
-
-
van Cutsem, E.1
Köhne, C.H.2
Hitre, E.3
Zaluski, J.4
Chien, C.R.C.5
Makhson, A.6
-
17
-
-
59949091448
-
Fluorouracil, leucovorin, and oxaliplatin with and without cetux-imab in the first-line treatment of metastatic colorectal cancer
-
[PMID: 19114683]
-
Bokemeyer C, Bondarenko I, Makhson A, Hartmann JT, Aparicio J, de Braud F, et al. Fluorouracil, leucovorin, and oxaliplatin with and without cetux-imab in the first-line treatment of metastatic colorectal cancer. J Clin Oncol. 2009;27:663-71. [PMID: 19114683]
-
(2009)
J Clin Oncol
, vol.27
, pp. 663-671
-
-
Bokemeyer, C.1
Bondarenko, I.2
Makhson, A.3
Hartmann, J.T.4
Aparicio, J.5
de Braud, F.6
-
18
-
-
70449420123
-
Use of archived specimens in evaluation of prognostic and predictive biomarkers
-
[PMID: 19815849]
-
Simon RM, Paik S, Hayes DF. Use of archived specimens in evaluation of prognostic and predictive biomarkers. J Natl Cancer Inst. 2009;101:1446-52. [PMID: 19815849]
-
(2009)
J Natl Cancer Inst
, vol.101
, pp. 1446-1452
-
-
Simon, R.M.1
Paik, S.2
Hayes, D.F.3
-
19
-
-
33745427131
-
Tracking the epidemiology of human genes in the literature: The HuGE Published Literature database
-
[PMID: 16641305]
-
Lin BK, Clyne M, Walsh M, Gomez O, Yu W, Gwinn M, et al. Tracking the epidemiology of human genes in the literature: the HuGE Published Literature database. Am J Epidemiol. 2006;164:1-4. [PMID: 16641305]
-
(2006)
Am J Epidemiol
, vol.164
, pp. 1-4
-
-
Lin, B.K.1
Clyne, M.2
Walsh, M.3
Gomez, O.4
Yu, W.5
Gwinn, M.6
-
20
-
-
77955084711
-
dbCPCO: A database of genetic markers tested for their predictive and prognostic value in colorectal cancer
-
[PMID: 20506273]
-
Savas S, Younghusband HB. dbCPCO: a database of genetic markers tested for their predictive and prognostic value in colorectal cancer. Hum Mutat. 2010; 31:901-7. [PMID: 20506273]
-
(2010)
Hum Mutat
, vol.31
, pp. 901-907
-
-
Savas, S.1
Younghusband, H.B.2
-
21
-
-
34548503420
-
End points in advanced colon cancer clinical trials: A review and proposal
-
[PMID: 17704403]
-
Allegra C, Blanke C, Buyse M, Goldberg R, Grothey A, Meropol NJ, et al. End points in advanced colon cancer clinical trials: a review and proposal. J Clin Oncol. 2007;25:3572-5. [PMID: 17704403]
-
(2007)
J Clin Oncol
, vol.25
, pp. 3572-3575
-
-
Allegra, C.1
Blanke, C.2
Buyse, M.3
Goldberg, R.4
Grothey, A.5
Meropol, N.J.6
-
22
-
-
59749089432
-
Targeted therapy for advanced colorectal cancer-more is not always better [Editorial]
-
[PMID: 19196680]
-
Mayer RJ. Targeted therapy for advanced colorectal cancer-more is not always better [Editorial]. N Engl J Med. 2009;360:623-5. [PMID: 19196680]
-
(2009)
N Engl J Med
, vol.360
, pp. 623-625
-
-
Mayer, R.J.1
-
23
-
-
62249094521
-
Overstating the evidence: Double counting in meta-analysis and related problems
-
[PMID: 19216779]
-
Senn SJ. Overstating the evidence: double counting in meta-analysis and related problems. BMC Med Res Methodol. 2009;9:10. [PMID: 19216779]
-
(2009)
BMC Med Res Methodol
, vol.9
, pp. 10
-
-
Senn, S.J.1
-
24
-
-
0032583387
-
Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints
-
[PMID: 9921604]
-
Parmar MK, Torri V, Stewart L. Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints. Stat Med. 1998; 17:2815-34. [PMID: 9921604]
-
(1998)
Stat Med
, vol.17
, pp. 2815-2834
-
-
Parmar, M.K.1
Torri, V.2
Stewart, L.3
-
25
-
-
13644267742
-
Meta-analysis when only the median survival times are known: A comparison with individual patient data results
-
[PMID: 15736523]
-
Michiels S, Piedbois P, Burdett S, Syz N, Stewart L, Pignon JP. Meta-analysis when only the median survival times are known: a comparison with individual patient data results. Int J Technol Assess Health Care. 2005;21:119-25. [PMID: 15736523]
-
(2005)
Int J Technol Assess Health Care
, vol.21
, pp. 119-125
-
-
Michiels, S.1
Piedbois, P.2
Burdett, S.3
Syz, N.4
Stewart, L.5
Pignon, J.P.6
-
26
-
-
34547450763
-
Practical methods for incorporating summary time-to-event data into meta-analysis
-
[PMID: 17555582]
-
Tierney JF, Stewart LA, Ghersi D, Burdett S, Sydes MR. Practical methods for incorporating summary time-to-event data into meta-analysis. Trials. 2007;8: 16. [PMID: 17555582]
-
(2007)
Trials
, vol.8
, pp. 16
-
-
Tierney, J.F.1
Stewart, L.A.2
Ghersi, D.3
Burdett, S.4
Sydes, M.R.5
-
28
-
-
23844534811
-
Reporting recommendations for tumor marker prognostic studies (REMARK)
-
[PMID: 16106022], Statistics Subcommittee of the NCI-EORTC Working Group on Cancer Diagnostics
-
McShane LM, Altman DG, Sauerbrei W, Taube SE, Gion M, Clark GM; Statistics Subcommittee of the NCI-EORTC Working Group on Cancer Diagnostics. Reporting recommendations for tumor marker prognostic studies (REMARK). J Natl Cancer Inst. 2005;97:1180-4. [PMID: 16106022]
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 1180-1184
-
-
McShane, L.M.1
Altman, D.G.2
Sauerbrei, W.3
Taube, S.E.4
Gion, M.5
Clark, G.M.6
-
29
-
-
84921702413
-
Interaction revisited: The difference between two estimates
-
[PMID: 12543843]
-
Altman DG, Bland JM. Interaction revisited: the difference between two estimates. BMJ. 2003;326:219. [PMID: 12543843]
-
(2003)
BMJ
, pp. 326
-
-
Altman, D.G.1
Bland, J.M.2
-
30
-
-
0028316145
-
Guidelines for meta-analyses evaluating diagnostic tests
-
[PMID: 8135452]
-
Irwig L, Tosteson AN, Gatsonis C, Lau J, Colditz G, Chalmers TC, et al. Guidelines for meta-analyses evaluating diagnostic tests. Ann Intern Med. 1994; 120:667-76. [PMID: 8135452]
-
(1994)
Ann Intern Med
, vol.120
, pp. 667-676
-
-
Irwig, L.1
Tosteson, A.N.2
Gatsonis, C.3
Lau, J.4
Colditz, G.5
Chalmers, T.C.6
-
31
-
-
58049206683
-
Cochrane Diagnostic Test Accuracy Working Group. Systematic reviews of diagnostic test accuracy
-
[PMID: 19075208]
-
Leeflang MM, Deeks JJ, Gatsonis C, Bossuyt PM; Cochrane Diagnostic Test Accuracy Working Group. Systematic reviews of diagnostic test accuracy. Ann Intern Med. 2008;149:889-97. [PMID: 19075208]
-
(2008)
Ann Intern Med
, vol.149
, pp. 889-897
-
-
Leeflang, M.M.1
Deeks, J.J.2
Gatsonis, C.3
Bossuyt, P.M.4
-
32
-
-
52749099497
-
Assessment of somatic k-RAS mutations as a mechanism associated with resistance to EGFR-targeted agents: A systematic review and meta-analysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancer
-
[PMID: 18804418]
-
Linardou H, Dahabreh IJ, Kanaloupiti D, Siannis F, Bafaloukos D, Kos-midis P, et al. Assessment of somatic k-RAS mutations as a mechanism associated with resistance to EGFR-targeted agents: a systematic review and meta-analysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancer. Lancet Oncol. 2008;9:962-72. [PMID: 18804418]
-
(2008)
Lancet Oncol
, pp. 962-972
-
-
Linardou, H.1
Dahabreh, I.J.2
Kanaloupiti, D.3
Siannis, F.4
Bafaloukos, D.5
Kos-Midis, P.6
-
33
-
-
0022992740
-
Meta-analysis in clinical trials
-
[PMID: 3802833]
-
DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials. 1986;7:177-88. [PMID: 3802833]
-
(1986)
Control Clin Trials
, vol.7
, pp. 177-188
-
-
Dersimonian, R.1
Laird, N.2
-
34
-
-
0041876133
-
Measuring inconsistency in meta-analyses
-
[PMID: 12958120]
-
Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ. 2003;327:557-60. [PMID: 12958120]
-
(2003)
BMJ
, vol.327
, pp. 557-560
-
-
Higgins, J.P.1
Thompson, S.G.2
Deeks, J.J.3
Altman, D.G.4
-
35
-
-
0028659004
-
Operating characteristics of a rank correlation test for publication bias
-
[PMID: 7786990]
-
Begg CB, Mazumdar M. Operating characteristics of a rank correlation test for publication bias. Biometrics. 1994;50:1088-101. [PMID: 7786990]
-
(1994)
Biometrics
, vol.50
, pp. 1088-1101
-
-
Begg, C.B.1
Mazumdar, M.2
-
36
-
-
0030922816
-
Bias in meta-analysis detected by a simple, graphical test
-
[PMID: 9310563]
-
Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ. 1997;315:629-34. [PMID: 9310563]
-
(1997)
BMJ
, vol.315
, pp. 629-634
-
-
Egger, M.1
Smith, G.D.2
Schneider, M.3
Minder, C.4
-
37
-
-
23644457189
-
In an empirical evaluation of the funnel plot, researchers could not visually identify publication bias
-
[PMID: 16085192]
-
Terrin N, Schmid CH, Lau J. In an empirical evaluation of the funnel plot, researchers could not visually identify publication bias. J Clin Epidemiol. 2005; 58:894-901. [PMID: 16085192]
-
(2005)
J Clin Epidemiol
, vol.58
, pp. 894-901
-
-
Terrin, N.1
Schmid, C.H.2
Lau, J.3
-
38
-
-
33748935095
-
The case of the misleading funnel plot
-
[PMID: 16974018]
-
Lau J, Ioannidis JP, Terrin N, Schmid CH, Olkin I. The case of the misleading funnel plot. BMJ. 2006;333:597-600. [PMID: 16974018]
-
(2006)
BMJ
, vol.333
, pp. 597-600
-
-
Lau, J.1
Ioannidis, J.P.2
Terrin, N.3
Schmid, C.H.4
Olkin, I.5
-
39
-
-
24944498883
-
Bivariate analysis of sensitivity and specificity produces informative summary measures in diagnostic reviews
-
[PMID: 16168343]
-
Reitsma JB, Glas AS, Rutjes AW, Scholten RJ, Bossuyt PM, Zwinderman AH. Bivariate analysis of sensitivity and specificity produces informative summary measures in diagnostic reviews. J Clin Epidemiol. 2005;58:982-90. [PMID: 16168343]
-
(2005)
J Clin Epidemiol
, vol.58
, pp. 982-990
-
-
Reitsma, J.B.1
Glas, A.S.2
Rutjes, A.W.3
Scholten, R.J.4
Bossuyt, P.M.5
Zwinderman, A.H.6
-
40
-
-
33750696367
-
Bivariate meta-analysis of sensitivity and specificity with sparse data: A generalized linear mixed model approach [Letter]
-
author reply 1332-3. [PMID: 17098577]
-
Chu H, Cole SR. Bivariate meta-analysis of sensitivity and specificity with sparse data: a generalized linear mixed model approach [Letter]. J Clin Epidemiol. 2006;59:1331-2; author reply 1332-3. [PMID: 17098577]
-
(2006)
J Clin Epidemiol
, vol.59
, pp. 1331-1332
-
-
Chu, H.1
Cole, S.R.2
-
41
-
-
68949144867
-
Meta-analysis of diagnostic accuracy using hierarchical logistic regression
-
Harbord RM, Whiting P. metandi: Meta-analysis of diagnostic accuracy using hierarchical logistic regression. Stata Journal. 2009;9:211-29.
-
(2009)
Stata Journal
, vol.9
, pp. 211-229
-
-
Harbord, R.M.1
Whiting, P.2
Metandi3
-
42
-
-
0042926567
-
Improved tests for a random effects meta-regression with a single covariate
-
[PMID: 12939780]
-
Knapp G, Hartung J. Improved tests for a random effects meta-regression with a single covariate. Stat Med. 2003;22:2693-710. [PMID: 12939780]
-
(2003)
Stat Med
, vol.22
, pp. 2693-2710
-
-
Knapp, G.1
Hartung, J.2
-
43
-
-
0037098178
-
How should meta-regression analyses be undertaken and interpreted?
-
[PMID: 12111920]
-
Thompson SG, Higgins JP. How should meta-regression analyses be undertaken and interpreted? Stat Med. 2002;21:1559-73. [PMID: 12111920]
-
(2002)
Stat Med
, vol.21
, pp. 1559-1573
-
-
Thompson, S.G.1
Higgins, J.P.2
-
44
-
-
0037186429
-
Advanced methods in meta-analysis: Multivariate approach and meta-regression
-
[PMID: 11836738]
-
van Houwelingen HC, Arends LR, Stijnen T. Advanced methods in meta-analysis: multivariate approach and meta-regression. Stat Med. 2002;21:589-624. [PMID: 11836738]
-
(2002)
Stat Med
, vol.21
, pp. 589-624
-
-
van Houwelingen, H.C.1
Arends, L.R.2
Stijnen, T.3
-
45
-
-
73649108585
-
Meta-Analyst: Software for meta-analysis of binary, continuous and diagnostic data
-
[PMID: 19961608]
-
Wallace BC, Schmid CH, Lau J, Trikalinos TA. Meta-Analyst: software for meta-analysis of binary, continuous and diagnostic data. BMC Med Res Meth-odol. 2009;9:80. [PMID: 19961608]
-
(2009)
BMC Med Res Meth-odol
, vol.9
, pp. 80
-
-
Wallace, B.C.1
Schmid, C.H.2
Lau, J.3
Trikalinos, T.A.4
-
46
-
-
59949102930
-
A randomized phase IIIB trial of chemotherapy, bevacizumab, and panitumumab compared with chemotherapy and bevacizumab alone for metastatic colorectal cancer
-
[PMID: 19114685]
-
Hecht JR, Mitchell E, Chidiac T, Scroggin C, Hagenstad C, Spigel D, et al. A randomized phase IIIB trial of chemotherapy, bevacizumab, and panitumumab compared with chemotherapy and bevacizumab alone for metastatic colorectal cancer. J Clin Oncol. 2009;27:672-80. [PMID: 19114685]
-
(2009)
J Clin Oncol
, vol.27
, pp. 672-680
-
-
Hecht, J.R.1
Mitchell, E.2
Chidiac, T.3
Scroggin, C.4
Hagenstad, C.5
Spigel, D.6
-
47
-
-
59749091477
-
Chemotherapy, bevacizumab, and cetuximab in metastatic colorectal cancer
-
[PMID: 19196673]
-
Tol J, Koopman M, Cats A, Rodenburg CJ, Creemers GJ, Schrama JG, et al. Chemotherapy, bevacizumab, and cetuximab in metastatic colorectal cancer. N Engl J Med. 2009;360:563-72. [PMID: 19196673]
-
(2009)
N Engl J Med
, vol.360
, pp. 563-572
-
-
Tol, J.1
Koopman, M.2
Cats, A.3
Rodenburg, C.J.4
Creemers, G.J.5
Schrama, J.G.6
-
48
-
-
73249130298
-
Tumour response and secondary resectability of colorectal liver metastases following neoadjuvant chemotherapy with cetuximab: The CELIM randomized phase 2 trial
-
[PMID: 19942479]
-
Folprecht G, Gruenberger T, Bechstein WO, Raab HR, Lordick F, Hart-mann JT, et al. Tumour response and secondary resectability of colorectal liver metastases following neoadjuvant chemotherapy with cetuximab: the CELIM randomized phase 2 trial. Lancet Oncol. 2010;11:38-47. [PMID: 19942479]
-
(2010)
Lancet Oncol
, vol.11
, pp. 38-47
-
-
Folprecht, G.1
Gruenberger, T.2
Bechstein, W.O.3
Raab, H.R.4
Lordick, F.5
Hart-Mann, J.T.6
-
49
-
-
67650366758
-
Detection of KRAS oncogene in peripheral blood as a predictor of the response to cetuximab plus chemotherapy in patients with metastatic colorectal cancer
-
[PMID: 19549774]
-
Yen LC, Yeh YS, Chen CW, Wang HM, Tsai HL, Lu CY, et al. Detection of KRAS oncogene in peripheral blood as a predictor of the response to cetuximab plus chemotherapy in patients with metastatic colorectal cancer. Clin Cancer Res. 2009;15:4508-13. [PMID: 19549774]
-
(2009)
Clin Cancer Res
, vol.15
, pp. 4508-4513
-
-
Yen, L.C.1
Yeh, Y.S.2
Chen, C.W.3
Wang, H.M.4
Tsai, H.L.5
Lu, C.Y.6
-
50
-
-
77954306356
-
Cetuximab administered once every second week to patients with metastatic colorectal cancer: A two-part pharmacokinetic/pharmacodynamic phase I dose-escalation study
-
[PMID: 19940007]
-
Tabernero J, Ciardiello F, Rivera F, Rodriguez-Braun E, Ramos FJ, Mar-tinelli E, et al. Cetuximab administered once every second week to patients with metastatic colorectal cancer: a two-part pharmacokinetic/pharmacodynamic phase I dose-escalation study. Ann Oncol. 2010;21:1537-45. [PMID: 19940007]
-
(2010)
Ann Oncol
, vol.21
, pp. 1537-1545
-
-
Tabernero, J.1
Ciardiello, F.2
Rivera, F.3
Rodriguez-Braun, E.4
Ramos, F.J.5
Mar-Tinelli, E.6
-
51
-
-
77449101632
-
Activating KRAS mutations and overexpression of epidermal growth factor receptor as independent predictors in metastatic colorectal cancer patients treated with cetuximab
-
[PMID: 20010090]
-
Yen LC, Uen YH, Wu DC, Lu CY, Yu FJ, Wu IC, et al. Activating KRAS mutations and overexpression of epidermal growth factor receptor as independent predictors in metastatic colorectal cancer patients treated with cetuximab. Ann Surg. 2010;251:254-60. [PMID: 20010090]
-
(2010)
Ann Surg
, vol.251
, pp. 254-260
-
-
Yen, L.C.1
Uen, Y.H.2
Wu, D.C.3
Lu, C.Y.4
Yu, F.J.5
Wu, I.C.6
-
52
-
-
17844362179
-
Gene copy number for epidermal growth factor receptor (EGFR) and clinical response to antiEGFR treatment in colorectal cancer: A cohort study
-
[PMID: 15863375]
-
Moroni M, Veronese S, Benvenuti S, Marrapese G, Sartore-Bianchi A, Di Nicolantonio F, et al. Gene copy number for epidermal growth factor receptor (EGFR) and clinical response to antiEGFR treatment in colorectal cancer: a cohort study. Lancet Oncol. 2005;6:279-86. [PMID: 15863375]
-
(2005)
Lancet Oncol
, vol.6
, pp. 279-286
-
-
Moroni, M.1
Veronese, S.2
Benvenuti, S.3
Marrapese, G.4
Sartore-Bianchi, A.5
Di Nicolantonio, F.6
-
53
-
-
33646228635
-
KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer
-
[PMID: 16618717]
-
Lievre A, Bachet JB, Le Corre D, Boige V, Landi B, Emile JF, et al. KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer. Cancer Res. 2006;66:3992-5. [PMID: 16618717]
-
(2006)
Cancer Res
, vol.66
, pp. 3992-3995
-
-
Lievre, A.1
Bachet, J.B.2
le Corre, D.3
Boige, V.4
Landi, B.5
Emile, J.F.6
-
54
-
-
34047248571
-
Oncogenic activation of the RAS/RAF signaling pathway impairs the response of metastatic colorectal cancers to anti-epidermal growth factor receptor antibody therapies
-
[PMID: 17363584]
-
Benvenuti S, Sartore-Bianchi A, Di Nicolantonio F, Zanon C, Moroni M, Veronese S, et al. Oncogenic activation of the RAS/RAF signaling pathway impairs the response of metastatic colorectal cancers to anti-epidermal growth factor receptor antibody therapies. Cancer Res. 2007;67:2643-8. [PMID: 17363584]
-
(2007)
Cancer Res
, vol.67
, pp. 2643-2648
-
-
Benvenuti, S.1
Sartore-Bianchi, A.2
Di Nicolantonio, F.3
Zanon, C.4
Moroni, M.5
Veronese, S.6
-
55
-
-
34247278727
-
Clinical relevance of KRAS mutation detection in metastatic colorectal cancer treated by Cetuximab plus chemotherapy
-
[PMID: 17375050]
-
Di Fiore F, Blanchard F, Charbonnier F, Le Pessot F, Lamy A, Galais MP, et al. Clinical relevance of KRAS mutation detection in metastatic colorectal cancer treated by Cetuximab plus chemotherapy. Br J Cancer. 2007;96:1166-9. [PMID: 17375050]
-
(2007)
Br J Cancer
, vol.96
, pp. 1166-1169
-
-
Di Fiore, F.1
Blanchard, F.2
Charbonnier, F.3
le Pessot, F.4
Lamy, A.5
Galais, M.P.6
-
56
-
-
35348908314
-
PTEN loss of expression predicts cetuximab efficacy in metastatic colorectal cancer patients
-
[PMID: 17940504]
-
Frattini M, Saletti P, Romagnani E, Martin V, Molinari F, Ghisletta M, et al. PTEN loss of expression predicts cetuximab efficacy in metastatic colorectal cancer patients. Br J Cancer. 2007;97:1139-45. [PMID: 17940504]
-
(2007)
Br J Cancer
, vol.97
, pp. 1139-1145
-
-
Frattini, M.1
Saletti, P.2
Romagnani, E.3
Martin, V.4
Molinari, F.5
Ghisletta, M.6
-
57
-
-
34548238762
-
Expression of epiregulin and amphiregulin and K-ras mutation status predict disease control in metastatic colorectal cancer patients treated with cetuximab
-
[PMID: 17664471]
-
Khambata-Ford S, Garrett CR, Meropol NJ, Basik M, Harbison CT, Wu S, et al. Expression of epiregulin and amphiregulin and K-ras mutation status predict disease control in metastatic colorectal cancer patients treated with cetuximab. J Clin Oncol. 2007;25:3230-7. [PMID: 17664471]
-
(2007)
J Clin Oncol
, vol.25
, pp. 3230-3237
-
-
Khambata-Ford, S.1
Garrett, C.R.2
Meropol, N.J.3
Basik, M.4
Harbison, C.T.5
Wu, S.6
-
58
-
-
46349092797
-
Primary resistance to cetuximab therapy in EGFR FISH-positive colorectal cancer patients
-
[PMID: 18577988]
-
Cappuzzo F, Varella-Garcia M, Finocchiaro G, Skokan M, Gajapathy S, Carnaghi C, et al. Primary resistance to cetuximab therapy in EGFR FISH-positive colorectal cancer patients. Br J Cancer. 2008;99:83-9. [PMID: 18577988]
-
(2008)
Br J Cancer
, vol.99
, pp. 83-89
-
-
Cappuzzo, F.1
Varella-Garcia, M.2
Finocchiaro, G.3
Skokan, M.4
Gajapathy, S.5
Carnaghi, C.6
-
59
-
-
40149088765
-
KRAS wild-type state predicts survival and is associated to early radiological response in metastatic colorectal cancer treated with cetuximab
-
[PMID: 17998284]
-
De Roock W, Piessevaux H, De Schutter J, Janssens M, De Hertogh G, Personeni N, et al. KRAS wild-type state predicts survival and is associated to early radiological response in metastatic colorectal cancer treated with cetuximab. Ann Oncol. 2008;19:508-15. [PMID: 17998284]
-
(2008)
Ann Oncol
, vol.19
, pp. 508-515
-
-
de Roock, W.1
Piessevaux, H.2
de Schutter, J.3
Janssens, M.4
de Hertogh, G.5
Personeni, N.6
-
60
-
-
57449095367
-
Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer
-
[PMID: 19001320]
-
Di Nicolantonio F, Martini M, Molinari F, Sartore-Bianchi A, Arena S, Saletti P, et al. Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer. J Clin Oncol. 2008;26:5705-12. [PMID: 19001320]
-
(2008)
J Clin Oncol
, vol.26
, pp. 5705-5712
-
-
Di Nicolantonio, F.1
Martini, M.2
Molinari, F.3
Sartore-Bianchi, A.4
Arena, S.5
Saletti, P.6
-
61
-
-
44449090596
-
Association of K-ras mutational status and clinical outcomes in patients with metastatic colorectal cancer receiving panitumumab alone
-
[PMID: 18621636]
-
Freeman DJ, Juan T, Reiner M, Hecht JR, Meropol NJ, Berlin J, et al. Association of K-ras mutational status and clinical outcomes in patients with metastatic colorectal cancer receiving panitumumab alone. Clin Colorectal Cancer. 2008;7:184-90. [PMID: 18621636]
-
(2008)
Clin Colorectal Cancer
, vol.7
, pp. 184-190
-
-
Freeman, D.J.1
Juan, T.2
Reiner, M.3
Hecht, J.R.4
Meropol, N.J.5
Berlin, J.6
-
62
-
-
45949083997
-
A polymorphism of EGFR extracellular domain is associated with progression free-survival in metastatic colorectal cancer patients receiving cetuximab-based treatment
-
[PMID: 18544172]
-
Goncalves A, Esteyries S, Taylor-Smedra B, Lagarde A, Ayadi M, Monges G, et al. A polymorphism of EGFR extracellular domain is associated with progression free-survival in metastatic colorectal cancer patients receiving cetuximab-based treatment. BMC Cancer. 2008;8:169. [PMID: 18544172]
-
(2008)
BMC Cancer
, vol.8
, pp. 169
-
-
Goncalves, A.1
Esteyries, S.2
Taylor-Smedra, B.3
Lagarde, A.4
Ayadi, M.5
Monges, G.6
-
63
-
-
38649099966
-
KRAS mutations as an independent prognostic factor in patients with advanced colorectal cancer treated with cetuximab
-
[PMID: 18202412]
-
Lievre A, Bachet JB, Boige V, Cayre A, Le Corre D, Buc E, et al. KRAS mutations as an independent prognostic factor in patients with advanced colorectal cancer treated with cetuximab. J Clin Oncol. 2008;26:374-9. [PMID: 18202412]
-
(2008)
J Clin Oncol
, vol.26
, pp. 374-379
-
-
Lievre, A.1
Bachet, J.B.2
Boige, V.3
Cayre, A.4
le Corre, D.5
Buc, E.6
-
64
-
-
59449091688
-
Polymorphisms in cyclooxygenase-2 and epidermal growth factor receptor are associated with progression-free survival independent of K-ras in metastatic colorectal cancer patients treated with single-agent cetuximab
-
[PMID: 19047118]
-
Lurje G, Nagashima F, Zhang W, Yang D, Chang HM, Gordon MA, et al. Polymorphisms in cyclooxygenase-2 and epidermal growth factor receptor are associated with progression-free survival independent of K-ras in metastatic colorectal cancer patients treated with single-agent cetuximab. Clin Cancer Res. 2008; 14:7884-95. [PMID: 19047118]
-
(2008)
Clin Cancer Res
, vol.14
, pp. 7884-7895
-
-
Lurje, G.1
Nagashima, F.2
Zhang, W.3
Yang, D.4
Chang, H.M.5
Gordon, M.A.6
-
65
-
-
53249123419
-
Clinical usefulness of EGFR gene copy number as a predictive marker in colorectal cancer patients treated with cetuximab: A fluorescent in situ hybridization study
-
[PMID: 18794099]
-
Personeni N, Fieuws S, Piessevaux H, De Hertogh G, De Schutter J, Biesmans B, et al. Clinical usefulness of EGFR gene copy number as a predictive marker in colorectal cancer patients treated with cetuximab: a fluorescent in situ hybridization study. Clin Cancer Res. 2008;14:5869-76. [PMID: 18794099]
-
(2008)
Clin Cancer Res
, vol.14
, pp. 5869-5876
-
-
Personeni, N.1
Fieuws, S.2
Piessevaux, H.3
de Hertogh, G.4
de Schutter, J.5
Biesmans, B.6
-
66
-
-
61449239114
-
Impact of FcyRIIa-FcyRIIIa polymorphisms and KRAS mutations on the clinical outcome of patients with metastatic colorectal cancer treated with cetuximab plus irinotecan
-
[PMID: 19164213]
-
Bibeau F, Lopez-Crapez E, Di Fiore F, Thezenas S, Ychou M, Blanchard F, et al. Impact of FcyRIIa-FcyRIIIa polymorphisms and KRAS mutations on the clinical outcome of patients with metastatic colorectal cancer treated with cetuximab plus irinotecan. J Clin Oncol. 2009;27:1122-9. [PMID: 19164213]
-
(2009)
J Clin Oncol
, vol.27
, pp. 1122-1129
-
-
Bibeau, F.1
Lopez-Crapez, E.2
Di Fiore, F.3
Thezenas, S.4
Ychou, M.5
Blanchard, F.6
-
67
-
-
65549143792
-
The importance of KRAS mutations and EGF61A>G polymorphism to the effect of cetuximab and irinotecan in metastatic colorectal cancer
-
[PMID: 19179548]
-
Garm Spindler KL, Pallisgaard N, Rasmussen AA, Lindebjerg J, Andersen RF, Cruger D, et al. The importance of KRAS mutations and EGF61A>G polymorphism to the effect of cetuximab and irinotecan in metastatic colorectal cancer. Ann Oncol. 2009;20:879-84. [PMID: 19179548]
-
(2009)
Ann Oncol
, vol.20
, pp. 879-884
-
-
Garm Spindler, K.L.1
Pallisgaard, N.2
Rasmussen, A.A.3
Lindebjerg, J.4
Andersen, R.F.5
Cruger, D.6
-
68
-
-
73349098041
-
Amphiregulin and epiregulin mRNA expression in primary tumors predicts outcome in metastatic colorectal cancer treated with cetuximab
-
[PMID: 19738126]
-
Jacobs B, De Roock W, Piessevaux H, Van Oirbeek R, Biesmans B, De Schutter J, et al. Amphiregulin and epiregulin mRNA expression in primary tumors predicts outcome in metastatic colorectal cancer treated with cetuximab. J Clin Oncol. 2009;27:5068-74. [PMID: 19738126]
-
(2009)
J Clin Oncol
, vol.27
, pp. 5068-5074
-
-
Jacobs, B.1
de Roock, W.2
Piessevaux, H.3
van Oirbeek, R.4
Biesmans, B.5
de Schutter, J.6
-
69
-
-
73349094741
-
Analysis of PTEN, BRAF, and EGFR status in determining benefit from cetuximab therapy in wild-type KRAS metastatic colon cancer
-
[PMID: 19884556]
-
Laurent-Puig P, Cayre A, Manceau G, Buc E, Bachet JB, Lecomte T, et al. Analysis of PTEN, BRAF, and EGFR status in determining benefit from cetuximab therapy in wild-type KRAS metastatic colon cancer. J Clin Oncol. 2009;27: 5924-30. [PMID: 19884556]
-
(2009)
J Clin Oncol
, vol.27
, pp. 5924-5930
-
-
Laurent-Puig, P.1
Cayre, A.2
Manceau, G.3
Buc, E.4
Bachet, J.B.5
Lecomte, T.6
-
70
-
-
66849140563
-
PTEN expression and KRAS mutations on primary tumors and metastases in the prediction of benefit from cetuximab plus irinotecan for patients with metastatic colorectal cancer
-
[PMID: 19398573]
-
Loupakis F, Pollina L, Stasi I, Ruzzo A, Scartozzi M, Santini D, et al. PTEN expression and KRAS mutations on primary tumors and metastases in the prediction of benefit from cetuximab plus irinotecan for patients with metastatic colorectal cancer. J Clin Oncol. 2009;27:2622-9. [PMID: 19398573]
-
(2009)
J Clin Oncol
, vol.27
, pp. 2622-2629
-
-
Loupakis, F.1
Pollina, L.2
Stasi, I.3
Ruzzo, A.4
Scartozzi, M.5
Santini, D.6
-
71
-
-
68749119351
-
KRAS codon 61, 146 and BRAF mutations predict resistance to cetuximab plus irinotecan in KRAS codon 12 and 13 wild-type metastatic colorectal cancer
-
[PMID: 19603018]
-
Loupakis F, Ruzzo A, Cremolini C, Vincenzi B, Salvatore L, Santini D, et al. KRAS codon 61, 146 and BRAF mutations predict resistance to cetuximab plus irinotecan in KRAS codon 12 and 13 wild-type metastatic colorectal cancer. Br J Cancer. 2009;101:715-21. [PMID: 19603018]
-
(2009)
Br J Cancer
, vol.101
, pp. 715-721
-
-
Loupakis, F.1
Ruzzo, A.2
Cremolini, C.3
Vincenzi, B.4
Salvatore, L.5
Santini, D.6
-
72
-
-
63949084084
-
Differing deregulation of EGFR and downstream proteins in primary colorectal cancer and related metastatic sites may be clinically relevant
-
[PMID: 19293803]
-
Molinari F, Martin V, Saletti P, De Dosso S, Spitale A, Camponovo A, et al. Differing deregulation of EGFR and downstream proteins in primary colorectal cancer and related metastatic sites may be clinically relevant. Br J Cancer. 2009;100:1087-94. [PMID: 19293803]
-
(2009)
Br J Cancer
, vol.100
, pp. 1087-1094
-
-
Molinari, F.1
Martin, V.2
Saletti, P.3
de Dosso, S.4
Spitale, A.5
Camponovo, A.6
-
73
-
-
65549128100
-
A phase 2 clinical trial of panitumumab monotherapy in Japanese patients with metastatic colorectal cancer
-
[PMID: 19287023]
-
Muro K, Yoshino T, Doi T, Shirao K, Takiuchi H, Hamamoto Y, et al. A phase 2 clinical trial of panitumumab monotherapy in Japanese patients with metastatic colorectal cancer. Jpn J Clin Oncol. 2009;39:321-6. [PMID: 19287023]
-
(2009)
Jpn J Clin Oncol
, vol.39
, pp. 321-326
-
-
Muro, K.1
Yoshino, T.2
Doi, T.3
Shirao, K.4
Takiuchi, H.5
Hamamoto, Y.6
-
74
-
-
65349149003
-
TP53 mutations predict disease control in metastatic colorectal cancer treated with cetuximab-based chemotherapy
-
[PMID: 19367287]
-
Oden-Gangloff A, Di Fiore F, Bibeau F, Lamy A, Bougeard G, Charbonnier F, et al. TP53 mutations predict disease control in metastatic colorectal cancer treated with cetuximab-based chemotherapy. Br J Cancer. 2009;100: 1330-5. [PMID: 19367287]
-
(2009)
Br J Cancer
, vol.100
, pp. 1330-1335
-
-
Oden-Gangloff, A.1
Di Fiore, F.2
Bibeau, F.3
Lamy, A.4
Bougeard, G.5
Charbonnier, F.6
-
75
-
-
59049089201
-
PI3KCA/PTEN deregulation contributes to impaired responses to cetuximab in metastatic colorectal cancer patients
-
[PMID: 18669866]
-
Perrone F, Lampis A, Orsenigo M, Di Bartolomeo M, Gevorgyan A, Losa M, et al. PI3KCA/PTEN deregulation contributes to impaired responses to cetuximab in metastatic colorectal cancer patients. Ann Oncol. 2009;20:84-90. [PMID: 18669866]
-
(2009)
Ann Oncol
, vol.20
, pp. 84-90
-
-
Perrone, F.1
Lampis, A.2
Orsenigo, M.3
Di Bartolomeo, M.4
Gevorgyan, A.5
Losa, M.6
-
76
-
-
65649086786
-
PIK3CA mutations are not a major determinant of resistance to the epidermal growth factor receptor inhibitor cetuximab in metastatic colorectal cancer
-
[PMID: 19366826]
-
Prenen H, De Schutter J, Jacobs B, De Roock W, Biesmans B, Claes B, et al. PIK3CA mutations are not a major determinant of resistance to the epidermal growth factor receptor inhibitor cetuximab in metastatic colorectal cancer. Clin Cancer Res. 2009;15:3184-8. [PMID: 19366826]
-
(2009)
Clin Cancer Res
, vol.15
, pp. 3184-3188
-
-
Prenen, H.1
de Schutter, J.2
Jacobs, B.3
de Roock, W.4
Biesmans, B.5
Claes, B.6
-
77
-
-
79951772042
-
MDR1 polymorphism role in patients treated with cetuximab and irinotecan in irinotecan refractory colorectal cancer
-
[PMID: 19862647]
-
Paule B, Castagne V, Picard V, Saffroy R, Adam R, Guettier C, et al. MDR1 polymorphism role in patients treated with cetuximab and irinotecan in irinotecan refractory colorectal cancer. Med Oncol. 2009. [PMID: 19862647]
-
(2009)
Med Oncol
-
-
Paule, B.1
Castagne, V.2
Picard, V.3
Saffroy, R.4
Adam, R.5
Guettier, C.6
-
78
-
-
62449302407
-
PIK3CA mutations in colorectal cancer are associated with clinical resistance to EGFR-targeted monoclonal antibodies
-
[PMID: 19223544]
-
Sartore-Bianchi A, Martini M, Molinari F, Veronese S, Nichelatti M, Artale S, et al. PIK3CA mutations in colorectal cancer are associated with clinical resistance to EGFR-targeted monoclonal antibodies. Cancer Res. 2009;69:1851-7. [PMID: 19223544]
-
(2009)
Cancer Res
, vol.69
, pp. 1851-1857
-
-
Sartore-Bianchi, A.1
Martini, M.2
Molinari, F.3
Veronese, S.4
Nichelatti, M.5
Artale, S.6
-
79
-
-
70350028742
-
Multi-determinants analysis of molecular alterations for predicting clinical benefit to EGFR-targeted monoclonal antibodies in colorectal cancer
-
[PMID: 19806185]
-
Sartore-Bianchi A, Di Nicolantonio F, Nichelatti M, Molinari F, De Dosso S, Saletti P, et al. Multi-determinants analysis of molecular alterations for predicting clinical benefit to EGFR-targeted monoclonal antibodies in colorectal cancer. PLoS One. 2009;4:e7287. [PMID: 19806185]
-
(2009)
PLoS One
, vol.4
-
-
Sartore-Bianchi, A.1
Di Nicolantonio, F.2
Nichelatti, M.3
Molinari, F.4
de Dosso, S.5
Saletti, P.6
-
80
-
-
69749104382
-
The role of KRAS mutations in predicting the efficacy of cetuximab-plus-irinotecan therapy in irinotecan-refractory Korean metastatic colorectal cancer patients
-
[PMID: 19738388]
-
Sohn BS, Kim TW, Lee JL, Ryu MH, Chang HM, Kang YK, et al. The role of KRAS mutations in predicting the efficacy of cetuximab-plus-irinotecan therapy in irinotecan-refractory Korean metastatic colorectal cancer patients. Oncology. 2009;77:224-30. [PMID: 19738388]
-
(2009)
Oncology
, vol.77
, pp. 224-230
-
-
Sohn, B.S.1
Kim, T.W.2
Lee, J.L.3
Ryu, M.H.4
Chang, H.M.5
Kang, Y.K.6
-
81
-
-
68149165771
-
Prognostic and predictive value of common mutations for treatment response and survival in patients with metastatic colorectal cancer
-
[PMID: 19603024]
-
Souglakos J, Philips J, Wang R, Marwah S, Silver M, Tzardi M, et al. Prognostic and predictive value of common mutations for treatment response and survival in patients with metastatic colorectal cancer. Br J Cancer. 2009;101:465-72. [PMID: 19603024]
-
(2009)
Br J Cancer
, vol.101
, pp. 465-472
-
-
Souglakos, J.1
Philips, J.2
Wang, R.3
Marwah, S.4
Silver, M.5
Tzardi, M.6
-
82
-
-
76149106147
-
Detection of tumor epidermal growth factor receptor pathway dependence by serum mass spectrometry in cancer patients
-
[PMID: 20086114]
-
Chung CH, Seeley EH, Roder H, Grigorieva J, Tsypin M, Roder J, et al. Detection of tumor epidermal growth factor receptor pathway dependence by serum mass spectrometry in cancer patients. Cancer Epidemiol Biomarkers Prev. 2010;19:358-65. [PMID: 20086114]
-
(2010)
Cancer Epidemiol Biomarkers Prev
, vol.19
, pp. 358-365
-
-
Chung, C.H.1
Seeley, E.H.2
Roder, H.3
Grigorieva, J.4
Tsypin, M.5
Roder, J.6
-
83
-
-
77957145245
-
Genetic modulation of the Let-7 microRNA binding to KRAS 3'-untranslated region and survival of metastatic colorectal cancer patients treated with salvage cetuximab-irinotecan
-
[PMID: 20177422]
-
Graziano F, Canestrari E, Loupakis F, Ruzzo A, Galluccio N, Santini D, et al. Genetic modulation of the Let-7 microRNA binding to KRAS 3'-untranslated region and survival of metastatic colorectal cancer patients treated with salvage cetuximab-irinotecan. Pharmacogenomics J. 2010;10:458-64. [PMID: 20177422]
-
(2010)
Pharmacogenomics J
, vol.10
, pp. 458-464
-
-
Graziano, F.1
Canestrari, E.2
Loupakis, F.3
Ruzzo, A.4
Galluccio, N.5
Santini, D.6
-
84
-
-
77950368212
-
Mitogen-activated protein kinase phosphatase-1 (MKP-1) impairs the response to anti-epidermal growth factor receptor (EGFR) antibody cetuximab in metastatic colorectal cancer patients
-
[PMID: 20234366]
-
Montagut C, Iglesias M, Arumi M, Bellosillo B, Gallen M, Martinez-Fernandez A, et al. Mitogen-activated protein kinase phosphatase-1 (MKP-1) impairs the response to anti-epidermal growth factor receptor (EGFR) antibody cetuximab in metastatic colorectal cancer patients. Br J Cancer. 2010;102:1137-44. [PMID: 20234366]
-
(2010)
Br J Cancer
, vol.102
, pp. 1137-1144
-
-
Montagut, C.1
Iglesias, M.2
Arumi, M.3
Bellosillo, B.4
Gallen, M.5
Martinez-Fernandez, A.6
-
85
-
-
77955604846
-
Additional value of EGFR downstream signaling phosphoprotein expression to KRAS status for response to anti-EGFR antibodies in colorectal cancer
-
[PMID: 20049837]
-
Perkins G, Lievre A, Ramacci C, Méatchi T, de Reynies A, Emile JF, et al. Additional value of EGFR downstream signaling phosphoprotein expression to KRAS status for response to anti-EGFR antibodies in colorectal cancer. Int J Cancer. 2010;127:1321-31. [PMID: 20049837]
-
(2010)
Int J Cancer
, vol.127
, pp. 1321-1331
-
-
Perkins, G.1
Lievre, A.2
Ramacci, C.3
Méatchi, T.4
Reynies, A.5
Emile, J.F.6
-
86
-
-
77956996167
-
Insulin-like growth factor 1 expression correlates with clinical outcome in K-RAS wild type colorectal cancer patients treated with cetuximab and irinotecan
-
[PMID: 20099280]
-
Scartozzi M, Mandolesi A, Giampieri R, Pierantoni C, Loupakis F, Zani-boni A, et al. Insulin-like growth factor 1 expression correlates with clinical outcome in K-RAS wild type colorectal cancer patients treated with cetuximab and irinotecan. Int J Cancer. 2010;127:1941-7. [PMID: 20099280]
-
(2010)
Int J Cancer
, vol.127
, pp. 1941-1947
-
-
Scartozzi, M.1
Mandolesi, A.2
Giampieri, R.3
Pierantoni, C.4
Loupakis, F.5
Zani-Boni, A.6
-
87
-
-
65349189958
-
American Society of Clinical Oncology provisional clinical opinion: Testing for KRAS gene mutations in patients with metastatic colorectal carcinoma to predict response to anti-epidermal growth factor receptor monoclonal antibody therapy
-
[PMID: 19188670]
-
Allegra CJ, Jessup JM, Somerfield MR, Hamilton SR, Hammond EH, Hayes DF, et al. American Society of Clinical Oncology provisional clinical opinion: testing for KRAS gene mutations in patients with metastatic colorectal carcinoma to predict response to anti-epidermal growth factor receptor monoclonal antibody therapy. J Clin Oncol. 2009;27:2091-6. [PMID: 19188670]
-
(2009)
J Clin Oncol
, vol.27
, pp. 2091-2096
-
-
Allegra, C.J.1
Jessup, J.M.2
Somerfield, M.R.3
Hamilton, S.R.4
Hammond, E.H.5
Hayes, D.F.6
-
88
-
-
78649965504
-
Clinical trials for predictive medicine: New challenges and paradigms
-
[PMID: 20338899]
-
Simon R. Clinical trials for predictive medicine: new challenges and paradigms. Clin Trials. 2010;7:516-24. [PMID: 20338899]
-
(2010)
Clin Trials
, vol.7
, pp. 516-524
-
-
Simon, R.1
-
89
-
-
73149107502
-
KRAS mutation in stage III colon cancer and clinical outcome following intergroup trial CALGB 89803
-
[PMID: 19934290], Cancer and Leukemia Group B
-
Ogino S, Meyerhardt JA, Irahara N, Niedzwiecki D, Hollis D, Saltz LB, et al; Cancer and Leukemia Group B. KRAS mutation in stage III colon cancer and clinical outcome following intergroup trial CALGB 89803. Clin Cancer Res. 2009;15:7322-9. [PMID: 19934290]
-
(2009)
Clin Cancer Res
, vol.15
, pp. 7322-7329
-
-
Ogino, S.1
Meyerhardt, J.A.2
Irahara, N.3
Niedzwiecki, D.4
Hollis, D.5
Saltz, L.B.6
-
90
-
-
9144231228
-
Molecular lesions in colorectal cancer: Impact on prognosis? Original data and review of the literature
-
[PMID: 12827409]
-
Klump B, Nehls O, Okech T, Hsieh CJ, Gaco V, Gittinger FS, et al. Molecular lesions in colorectal cancer: impact on prognosis? Original data and review of the literature. Int J Colorectal Dis. 2004;19:23-42. [PMID: 12827409]
-
(2004)
Int J Colorectal Dis
, vol.19
, pp. 23-42
-
-
Klump, B.1
Nehls, O.2
Okech, T.3
Hsieh, C.J.4
Gaco, V.5
Gittinger, F.S.6
-
91
-
-
84922359109
-
-
U.S. Food and Drug Administration, 22 September 2010
-
U.S. Food and Drug Administration. Panitumumab: highlights of prescribing information. 2009. Accessed at www.accessdata.fda.gov/drugsatfda_docs/label/2009/125147s080lbl.pdf on 22 September 2010.
-
(2009)
Panitumumab: Highlights of Prescribing Information
-
-
-
92
-
-
76949095166
-
KRAS mutational status assessment in patients with metastatic colorectal cancer: Are the clinical implications so clear?
-
[PMID: 19702696]
-
Hebbar M, Fournier P, Romano O. KRAS mutational status assessment in patients with metastatic colorectal cancer: are the clinical implications so clear? Eur J Cancer Care (Engl). 2010;19:167-71. [PMID: 19702696]
-
(2010)
Eur J Cancer Care (Engl)
, vol.19
, pp. 167-171
-
-
Hebbar, M.1
Fournier, P.2
Romano, O.3
-
93
-
-
69849108427
-
Clinical trial designs for predictive biomarker validation: Theoretical considerations and practical challenges
-
[PMID: 19597023]
-
Mandrekar SJ, Sargent DJ. Clinical trial designs for predictive biomarker validation: theoretical considerations and practical challenges. J Clin Oncol. 2009;27:4027-34. [PMID: 19597023]
-
(2009)
J Clin Oncol
, vol.27
, pp. 4027-4034
-
-
Mandrekar, S.J.1
Sargent, D.J.2
|