Matrilysin (MMP-7) Inhibition of BMP-7 Induced Renal Tubular Branching Morphogenesis Suggests a Role in the Pathogenesis of Human Renal Dysplasia

Journal of Histochemistry and Cytochemistry

Volumn 60, Issue 3, 2012, Pages 243-253

  McGuire, John K ^a   Harju Baker, Susanna ^a   Rims, Cliff ^a   Sheen, Joong Hyuk ^a   Liapis, Helen ^b  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b WASHINGTON UNIVERSITY   (United States)

Author keywords

growth factors; kidney development; matrix metalloproteinases; renal dysplasia

Indexed keywords

MATRILYSIN; MATRILYSIN INHIBITOR; OSTEOGENIC PROTEIN 1; RECOMBINANT OSTEOGENIC PROTEIN 1; SCATTER FACTOR; SMAD PROTEIN; MMP7 PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRANCHING MORPHOGENESIS; CONTROLLED STUDY; ENZYME ACTIVITY; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; KIDNEY DEVELOPMENT; KIDNEY DISTAL TUBULE; KIDNEY DYSPLASIA; KIDNEY TUBULE; MOUSE; NONHUMAN; OPOSSUM; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ADULT; ANIMAL; CELL STRAIN HEK293; CONGENITAL MALFORMATION; DRUG ANTAGONISM; DRUG EFFECT; EPITHELIUM CELL; GENETICS; IMMUNOHISTOCHEMISTRY; KIDNEY; KIDNEY COLLECTING TUBULE; KIDNEY POLYCYSTIC DISEASE; METABOLISM; MORPHOGENESIS; PATHOLOGY; PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

DIDELPHIDAE;

ADULT; ANIMALS; BONE MORPHOGENETIC PROTEIN 7; DIDELPHIS; EPITHELIAL CELLS; HEK293 CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; KIDNEY; KIDNEY DISEASES, CYSTIC; KIDNEY TUBULES, COLLECTING; MATRIX METALLOPROTEINASE 7; MICE; MORPHOGENESIS; PHOSPHORYLATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 84859628045     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1369/0022155411435152     Document Type: Article

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