In vitro antimalarial activity and molecular docking analysis of 4-aminoquinoline-clubbed 1,3,5-triazine derivatives

Letters in Applied Microbiology

Volumn 54, Issue 5, 2012, Pages 483-486

  Bhat, H R ^a   Ghosh, S K ^b   Prakash, A ^c   Gogoi, K ^c   Singh, U P ^a  

^a SAM HIGGINBOTTOM UNIVERSITY OF AGRICULTURE   (India)

^b DIBRUGARH UNIVERSITY   (India)

^c REGIONAL MEDICAL RESEARCH CENTRE   (India)

Author keywords

Antimicrobials; Infection; Pharmaceuticals; Protozoa

Indexed keywords

BIOACTIVITY; HYDROGEN BONDS; HYDROPHOBICITY; LIGANDS;

ACTIVE SITE; AMINOQUINOLINE; ANTIMALARIAL ACTIVITY; ANTIMICROBIAL; IN-VITRO; INFECTION; MOLECULAR DOCKING; PLASMODIUM FALCIPARUM; STRUCTURAL REQUIREMENTS; TRIAZINE DERIVATIVES;

MOLECULES;

4 AMINOQUINOLINE; ANTIMALARIAL AGENT; CHLOROQUINE; N 2 [3 (7 CHLOROQUINOLIN 4 YLAMINO)PROPYL] N 4,N 6 DIISOPROPYL 1,3,5 TRIAZINE 2,4,6 TRIAMINE; TRIAZINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; ANTIMALARIAL DRUG SUSCEPTIBILITY; COMPETITIVE INHIBITION; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; HYDROGEN BOND; HYDROPHOBICITY; IN VITRO STUDY; LETTER; MOLECULAR DOCKING; NONHUMAN; PARASITEMIA; PLASMODIUM FALCIPARUM; PROTEIN PROTEIN INTERACTION; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION;

PLASMODIUM FALCIPARUM; PROTOZOA;

EID: 84859612359     PISSN: 02668254     EISSN: 1472765X     Source Type: Journal    
DOI: 10.1111/j.1472-765X.2012.03234.x     Document Type: Letter

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