Mapping of gene expression reveals CYP27A1 as a susceptibility gene for sporadic ALS

PLoS ONE

Volumn 7, Issue 4, 2012, Pages

  Diekstra, Frank P ^a   Saris, Christiaan G J ^a   van Rheenen, Wouter ^a   Franke, Lude ^b   Jansen, Ritsert C ^b,c   van Es, Michael A ^a   van Vught, Paul W J ^a   Blauw, Hylke M ^a   Groen, Ewout J N ^a   Horvath, Steve ^d   Estrada, Karol ^e   Rivadeneira, Fernando ^e   Hofman, Albert ^e   Uitterlinden, Andre G ^e   Robberecht, Wim ^f,g   Andersen, Peter M ^h   Melki, Judith ⁱ   Meininger, Vincent ^j   Hardiman, Orla ^k,l   Landers, John E ^m,n   Brown, Robert H ^m,n   Shatunov, Aleksey ^o   Shaw, Christopher E ^o   Leigh, P Nigel ^o   Al Chalabi, Ammar ^o   Ophoff, Roel A ^a,p   van den Berg, Leonard H ^a   Veldink, Jan H ^a   more..

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^c UNIVERSITY OF GRONINGEN   (Netherlands)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e ERASMUS MEDICAL CENTER   (Netherlands)

^f UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^g DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^h UMEÅ UNIVERSITY   (Sweden)

ⁱ UNIVERSITÉ PARIS DESCARTES   (France)

^j PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^k BEAUMONT HOSPITAL   (Ireland)

^l TRINITY COLLEGE DUBLIN   (Ireland)

^m UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

ⁿ MASSACHUSETTS GENERAL HOSPITAL   (United States)

^o KING'S COLLEGE LONDON   (United Kingdom)

^p UNIVERSITY OF CALIFORNIA   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CELL LOSS; CEREBROTENDINOUS XANTHOMATOSIS; CONTROLLED STUDY; CYP27A1 GENE; GENE; GENE EXPRESSION; GENE MAPPING; GENE MUTATION; GENE REPLICATION; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MOTONEURON; PATHOGENESIS; QUANTITATIVE TRAIT LOCUS; SINGLE NUCLEOTIDE POLYMORPHISM; GENE EXPRESSION PROFILING; GENE LINKAGE DISEQUILIBRIUM; GENETIC PREDISPOSITION; GENETICS; HAPLOTYPE MAP; PATHOLOGY; PEDIGREE;

CHOLESTANETRIOL 26 MONOOXYGENASE; CYP27A1 PROTEIN, HUMAN;

AMYOTROPHIC LATERAL SCLEROSIS; CYTOCHROME P-450 CYP27A1; GENE EXPRESSION PROFILING; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HAPMAP PROJECT; HUMANS; LINKAGE DISEQUILIBRIUM; MOTOR NEURONS; PEDIGREE; POLYMORPHISM, SINGLE NUCLEOTIDE; QUANTITATIVE TRAIT LOCI; XANTHOMATOSIS, CEREBROTENDINOUS;

EID: 84859612326     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0035333     Document Type: Article

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