메뉴 건너뛰기




Volumn 12, Issue 3, 2012, Pages 375-381

Lactic acid production in Saccharomyces cerevisiae is modulated by expression of the monocarboxylate transporters Jen1 and Ady2

Author keywords

ADY2; JEN1; Lactic acid; Metabolic engineering; Monocarboxylate permeases; Saccharomyces cerevisiae

Indexed keywords

ACETATE PERMEASE; LACTATE DEHYDROGENASE; LACTIC ACID; MONOCARBOXYLATE PERMEASE; MONOCARBOXYLATE TRANSPORTER; MONOCARBOXYLATE TRANSPORTER ADY2; MONOCARBOXYLATE TRANSPORTER JEN1; PERMEASE; UNCLASSIFIED DRUG;

EID: 84859600563     PISSN: 15671356     EISSN: 15671364     Source Type: Journal    
DOI: 10.1111/j.1567-1364.2012.00790.x     Document Type: Article
Times cited : (82)

References (25)
  • 2
    • 0035656862 scopus 로고    scopus 로고
    • Efficient homolactic fermentation by Kluyveromyces lactis strains defective in pyruvate utilization and transformed with the heterologous LDH gene
    • Bianchi MM, Brambilla L, Protani F, Liu CL, Lievense J & Porro D (2001) Efficient homolactic fermentation by Kluyveromyces lactis strains defective in pyruvate utilization and transformed with the heterologous LDH gene. Appl Environ Microbiol 67: 5621-5625.
    • (2001) Appl Environ Microbiol , vol.67 , pp. 5621-5625
    • Bianchi, M.M.1    Brambilla, L.2    Protani, F.3    Liu, C.L.4    Lievense, J.5    Porro, D.6
  • 3
    • 0742321952 scopus 로고    scopus 로고
    • The yeast Zygosaccharomyces bailii: a new host for heterologous protein production, secretion and for metabolic engineering applications
    • Branduardi P, Valli M, Brambilla L, Sauer M, Alberghina L & Porro D (2004) The yeast Zygosaccharomyces bailii: a new host for heterologous protein production, secretion and for metabolic engineering applications. FEMS Yeast Res 4: 493-504.
    • (2004) FEMS Yeast Res , vol.4 , pp. 493-504
    • Branduardi, P.1    Valli, M.2    Brambilla, L.3    Sauer, M.4    Alberghina, L.5    Porro, D.6
  • 4
    • 33144462944 scopus 로고    scopus 로고
    • Lactate production yield from engineered yeasts is dependent from the host background, the lactate dehydrogenase source and the lactate export
    • Branduardi P, Sauer M, De Gioia L, Zampella G, Valli M, Mattanovich D & Porro D (2006) Lactate production yield from engineered yeasts is dependent from the host background, the lactate dehydrogenase source and the lactate export. Microb Cell Fact 5: 4.
    • (2006) Microb Cell Fact , vol.5 , pp. 4
    • Branduardi, P.1    Sauer, M.2    De Gioia, L.3    Zampella, G.4    Valli, M.5    Mattanovich, D.6    Porro, D.7
  • 5
    • 0029020764 scopus 로고
    • Utilization of short-chain monocarboxylic acids by the yeast Torulaspora delbruekii: specificity of the transport systems and their regulation
    • Casal M & Leão C (1995) Utilization of short-chain monocarboxylic acids by the yeast Torulaspora delbruekii: specificity of the transport systems and their regulation. Biochim Biophys Acta 1267: 122-130.
    • (1995) Biochim Biophys Acta , vol.1267 , pp. 122-130
    • Casal, M.1    Leão, C.2
  • 6
    • 0030001104 scopus 로고    scopus 로고
    • Mechanisms regulating the transport of acetic acid in Saccharomyces cerevisiae
    • Casal M, Cardoso H & Leão C (1996) Mechanisms regulating the transport of acetic acid in Saccharomyces cerevisiae. Microbiology 142: 1385-1390.
    • (1996) Microbiology , vol.142 , pp. 1385-1390
    • Casal, M.1    Cardoso, H.2    Leão, C.3
  • 7
    • 0032911915 scopus 로고    scopus 로고
    • The lactate-proton symport of Saccharomyces cerevisiae is encoded by JEN1
    • Casal M, Paiva S, Andrade RP & Leão C (1999) The lactate-proton symport of Saccharomyces cerevisiae is encoded by JEN1. J Bacteriol 181: 2620-2623.
    • (1999) J Bacteriol , vol.181 , pp. 2620-2623
    • Casal, M.1    Paiva, S.2    Andrade, R.P.3    Leão, C.4
  • 8
    • 14744294675 scopus 로고
    • Mixed lactic acid-alcoholic fermentation by Saccharomyces cerevisiae expressing the Lactobacillus casei L(+)-LDH
    • Dequin S & Barre P (1994) Mixed lactic acid-alcoholic fermentation by Saccharomyces cerevisiae expressing the Lactobacillus casei L(+)-LDH. Biotechnology 12: 173-177.
    • (1994) Biotechnology , vol.12 , pp. 173-177
    • Dequin, S.1    Barre, P.2
  • 9
    • 84859616870 scopus 로고    scopus 로고
    • Laboratory evolution of new lactate transporter genes in a jen1Delta mutant of Saccharomyces cerevisiae and their identification as ADY2 alleles by whole-genome resequencing and transcriptome analysis
    • doi: 10.1111/j.1567-1364.2012.00787.x.
    • de Kok S, Nijkamp JF, Oud B, Roque FC, de Ridder D, Daran JM, Pronk JT & van Maris AJ (2012) Laboratory evolution of new lactate transporter genes in a jen1Delta mutant of Saccharomyces cerevisiae and their identification as ADY2 alleles by whole-genome resequencing and transcriptome analysis. FEMS Yeast Res. doi: 10.1111/j.1567-1364.2012.00787.x.
    • (2012) FEMS Yeast Res
    • de Kok, S.1    Nijkamp, J.F.2    Oud, B.3    Roque, F.C.4    de Ridder, D.5    Daran, J.M.6    Pronk, J.T.7    van Maris, A.J.8
  • 10
    • 0036270543 scopus 로고    scopus 로고
    • Transformation of yeast by lithium acetate/single-stranded carrier DNA/polyethylene glycol method
    • Gietz RD & Woods RA (2002) Transformation of yeast by lithium acetate/single-stranded carrier DNA/polyethylene glycol method. Methods Enzymol 350: 87-96.
    • (2002) Methods Enzymol , vol.350 , pp. 87-96
    • Gietz, R.D.1    Woods, R.A.2
  • 11
    • 69949187997 scopus 로고    scopus 로고
    • Genetic engineering of Candida utilis yeast for efficient production of L-lactic acid
    • Ikushima S, Fujii T, Kobayashi O, Yoshida S & Yoshida A (2009) Genetic engineering of Candida utilis yeast for efficient production of L-lactic acid. Biosci Biotechnol Biochem 73: 1818-1824.
    • (2009) Biosci Biotechnol Biochem , vol.73 , pp. 1818-1824
    • Ikushima, S.1    Fujii, T.2    Kobayashi, O.3    Yoshida, S.4    Yoshida, A.5
  • 14
    • 0028953840 scopus 로고
    • Yeast vectors for the controlled expression of heterologous proteins in different genetic backgrounds
    • Mumberg D, Muller R, Funk & M. (1995) Yeast vectors for the controlled expression of heterologous proteins in different genetic backgrounds. Gene 156: 119-122.
    • (1995) Gene , vol.156 , pp. 119-122
    • Mumberg, D.1    Muller, R.2    Funk, M.3
  • 15
    • 0020689374 scopus 로고
    • Genetic applications of yeast transformation with linear and gapped plasmids
    • Orr-Weaver TL, Szostak JW, Rothstein & RJ (1983) Genetic applications of yeast transformation with linear and gapped plasmids. Methods Enzymol 101: 228-245.
    • (1983) Methods Enzymol , vol.101 , pp. 228-245
    • Orr-Weaver, T.L.1    Szostak, J.W.2    Rothstein, R.J.3
  • 17
    • 1342290477 scopus 로고    scopus 로고
    • Ady2p is essential for the acetate permease activity in the yeast Saccharomyces cerevisiae
    • Paiva S, Devaux F, Barbosa S, Jacq C & Casal M (2004) Ady2p is essential for the acetate permease activity in the yeast Saccharomyces cerevisiae. Yeast. 21: 201-210.
    • (2004) Yeast. , vol.21 , pp. 201-210
    • Paiva, S.1    Devaux, F.2    Barbosa, S.3    Jacq, C.4    Casal, M.5
  • 18
    • 0029294111 scopus 로고
    • Development of metabolically engineered Saccharomyces cerevisiae cells for the production of lactic acid
    • Porro D, Brambilla L, Ranzi BM, Martegani E & Alberghina L (1995) Development of metabolically engineered Saccharomyces cerevisiae cells for the production of lactic acid. Biotechnol Prog 11: 294-298.
    • (1995) Biotechnol Prog , vol.11 , pp. 294-298
    • Porro, D.1    Brambilla, L.2    Ranzi, B.M.3    Martegani, E.4    Alberghina, L.5
  • 19
    • 0032825184 scopus 로고    scopus 로고
    • Replacement of a metabolic pathway for large-scale production of lactic acid from engineered yeasts
    • Porro D, Bianchi MM, Brambilla L et al. (1999a) Replacement of a metabolic pathway for large-scale production of lactic acid from engineered yeasts. Appl Environ Microbiol 65: 4211-4215.
    • (1999) Appl Environ Microbiol , vol.65 , pp. 4211-4215
    • Porro, D.1    Bianchi, M.M.2    Brambilla, L.3
  • 21
    • 79551577475 scopus 로고    scopus 로고
    • 16 years research on lactic acid production with yeast - ready for the market?
    • Sauer M, Porro D, Mattanovich D & Branduardi P (2010) 16 years research on lactic acid production with yeast - ready for the market? Biotechnol Genetic Eng Rev 27: 229-256.
    • (2010) Biotechnol Genetic Eng Rev , vol.27 , pp. 229-256
    • Sauer, M.1    Porro, D.2    Mattanovich, D.3    Branduardi, P.4
  • 22
    • 34548071932 scopus 로고    scopus 로고
    • The conserved sequence NXX[S/T]HX[S/T]QDXXXT of the lactate/pyruvate:H+ symporter subfamily defines the function of the substrate translocation pathway
    • Soares-Silva I, Paiva S, Diallinas G & Casal M (2007) The conserved sequence NXX[S/T]HX[S/T]QDXXXT of the lactate/pyruvate:H+ symporter subfamily defines the function of the substrate translocation pathway. Mol Membr Biol 24: 464-474.
    • (2007) Mol Membr Biol , vol.24 , pp. 464-474
    • Soares-Silva, I.1    Paiva, S.2    Diallinas, G.3    Casal, M.4
  • 23
    • 0024977417 scopus 로고
    • Elevated recombination rates in transcriptionally active DNA
    • Thomas BJ & Rothstein R (1989) Elevated recombination rates in transcriptionally active DNA. Cell 56: 619-630.
    • (1989) Cell , vol.56 , pp. 619-630
    • Thomas, B.J.1    Rothstein, R.2
  • 24
    • 62949109270 scopus 로고    scopus 로고
    • Double mutation of the PDC1 and ADH1 genes improves lactate production in the yeast Saccharomces cerevisiae expressing the bovine lactate dehydrogenase gene
    • Tokuhiro K, Ishida N, Nagamori E, Saitoh S, Onishi T, Kondo A & Takahashi H (2009) Double mutation of the PDC1 and ADH1 genes improves lactate production in the yeast Saccharomces cerevisiae expressing the bovine lactate dehydrogenase gene. Appl Microbiol Biotechnol 82: 883-890.
    • (2009) Appl Microbiol Biotechnol , vol.82 , pp. 883-890
    • Tokuhiro, K.1    Ishida, N.2    Nagamori, E.3    Saitoh, S.4    Onishi, T.5    Kondo, A.6    Takahashi, H.7
  • 25
    • 2442640659 scopus 로고    scopus 로고
    • Homofermentative lactate production cannot sustain anaerobic growth of engineered Saccharomyces cerevisiae: possible consequence ofenergy-dependent lactate export
    • van Maris AJA, Winkler AA, Porro D, van Dijken JP & Pronk JT (2004) Homofermentative lactate production cannot sustain anaerobic growth of engineered Saccharomyces cerevisiae: possible consequence ofenergy-dependent lactate export. Appl Environ Microbiol 70: 2898-2905.
    • (2004) Appl Environ Microbiol , vol.70 , pp. 2898-2905
    • van Maris, A.J.A.1    Winkler, A.A.2    Porro, D.3    van Dijken, J.P.4    Pronk, J.T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.