Neuroprotective effect of Rhizoma atractylodis macrocephalae against excitotoxicity-induced apoptosis in cultured cerebral cortical neurons

Phytotherapy Research

Volumn 26, Issue 4, 2012, Pages 557-561

  Gao, Qun ^a   Ji, Zhi Hong ^a   Yang, Yang ^a   Cheng, Rui ^a   Yu, Xin Yu ^a  

^a DALIAN UNIVERSITY   (China)

Author keywords

apoptosis; cerebral cortical neuron; excitotoxicity; neuroprotection; Rhizoma Atractylodis macrocephalae

Indexed keywords

ATRACTYLODES MACROCEPHALA EXTRACT; DNA; GLUTAMIC ACID;

ANIMAL CELL; APOPTOSIS; ARTICLE; ATRACTYLODES; ATRACTYLODES MACROCEPHALA; BRAIN CORTEX; CELL ASSAY; CELL COUNT; CELL DEATH; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; DNA FRAGMENTATION; EXCITOTOXICITY; FLOW CYTOMETRY; MOUSE; NERVE CELL CULTURE; NEUROPROTECTION; NONHUMAN; RHIZOME;

ANIMALS; APOPTOSIS; ATRACTYLODES; BISBENZIMIDAZOLE; CELL SURVIVAL; CEREBRAL CORTEX; DNA FRAGMENTATION; DRUG EVALUATION, PRECLINICAL; EMBRYO, MAMMALIAN; FEMALE; FLOW CYTOMETRY; GLUTAMIC ACID; MICE; MICE, INBRED BALB C; NEURONS; NEUROPROTECTIVE AGENTS; PLANT EXTRACTS; PREGNANCY; PRIMARY CELL CULTURE; TIME FACTORS;

EID: 84859599225     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.3595     Document Type: Article

References (32)

1. Ankarcrona M, Dypbukt JM, Bonfoco E, et al,. 1995. Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondria function. Neuron 15: 961-973.
2. Arthur PG, Matich GP, Pang WW, et al,. 2007. Necrotic death of neurons following an excitotoxic insult is prevented by a peptide inhibitor of c-jun N-terminal kinase. J Neurochem 102: 65-76.
3. Bonfoco E, Krainc D, Ankarcrona M, et al,. 1995. Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl- d -aspartate or nitric oxide/superoxide in cortical cell cultures. Proc Natl Acad Sci USA 92: 7162-7166.
4. Chen W, He GF, Jiang MH, et al,. 2007. Advances of the rhizome of Atractylodis macrocephalae Koidz, during the recent decades. Lishizhen Med Met Med Res 18: 338-340.
5. Chen ZL, Cao WY, Zhou GX, et al,. 1997. A sesquiterpene lactam from Atractylodes macrocephala. J Phytochem 54: 765-767.
6. Cheung NS, Pascoe CJ, Giardina SF, et al,. 1998. Micromolar l -glutamate induces extensive apoptosis in an apoptotic-necrotic continuum of insult-dependent, excitotoxic injury in cultured cortical neurons. Neuropharmacology 37: 1419-1429.
7. Chihab R, Oillet J, Bossenmeyer C, et al,. 1998. Glutamate triggers cell death specifically in mature central neurons through a necrotic process. Mol Genet Metab 63: 142-147.
8. Cho J, Joo NE, Kong JY, et al,. 2000. Inhibition of excitotoxic neuronal death by methanol extract of Acori graminei rhizoma in cultured rat cortical neurons. J Ethnopharmacol 73: 31-37.
9. Choi DW,. 1998. Glutamate neurotoxicity and diseases of the nervous system. Neuron 1: 623-634.
10. Dasari VR, Veeravalli KK, Saving KL, et al,. 2008. Neuroprotection by cord blood stem cells against glutamate-induced apoptosis is mediated by Akt pathway. Neurobiol Dis 32: 486-498.
11. Hansen MB, Nielsen SE, Berg K,. 1989. Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill. J Immunol Methods 119: 203-210.
12. Hetman M, Kanning K, Smith-Cavanaugh JE, et al,. 1999. Neuroprotection by brain-derived neurotrophic factor is mediated by extracellular-signal-regulated kinase and phosphatidylinositol-3 kinase. J Biol Chem 274: 22569-22580.
13. Kerr JFR, Harmon BV,. 1991. Definition and incidence of apoptosis: an historical perspective. In The Molecular Basis of Cell Death, Tomei LD, (ed.). Cold Spring Harbor Laboratory Press: New York, 5-31.
14. Kim YC, Kim SR, Markelonis GJ, et al,. 1998. Ginsenosides Rb1 and Rg3 protect cultured rat cortical cells from glutamate-induced neurodegeneration. J Neurosci Res 4: 426-432.
15. Kume T, Asai K, Nishikawa H, et al,. 2002. Isolation of a diterpenoid substance with potent neuroprotective activity from fetal calf serum. Proc Natl Acad Sci USA 5: 3288-3293.
16. Kume T, Kohchiyama H, Nishikawa H, et al,. 1997. Ether extract of fetal calf serum protects cultured rat cortical neurons against glutamate cytotoxicity. Jpn J Pharmacol 4: 3741-3744.
17. Li W, Wen HM, Cui XB, et al,. 2007. Chemical constituents of Rhizoma Atractylodis macrocephalae. Chin Tradit Herbal Drugs 38: 1460-1462.
18. Lipton SA, Rosenberg PA,. 1994. Excitatory amino acids as a final common pathway for neurologic disorders. N Engl J Med 9: 613-622.
19. Mattson MP, Rychlik B,. 1990. Glia protects hippocampal neurons against excitatory amino acid-induced degeneration: involvement of fibroblast growth factor. Int J Dev Neurosci 8: 399-415.
20. Nakao N, Grasbon-Frodl EM, Widner H, et al,. 1996. Antioxidant treatment protects striatal neurons against excitotoxic insults. Neuroscience 73: 185-200.
21. Olney JW,. 1986. Inciting excitotoxic cytocide among central neurons. Adv Exp Med Biol 203: 631-645.
22. Ormerod MG, Orr RM, Peacock JH,. 1994. The role of apoptosis in cell killing by cisplatin: a flow cytometric study. Br J Cancer 69: 93-100.
23. Portera-Cailliau C, Price DL, Martin LJ,. 1997. Excitotoxic neuronal death in the immature brain is an apoptosis-necrosis morphological continuum. J Comp Neurol 378: 70-87.
24. Sastry PS, Rao KS,. 2000. Apoptosis and the nervous system. J Neurochem 74: 1-20.
25. Sauer D, Fagg GE,. 1992. Excitatory amino acids, excitotoxicity and neurodegenerative disorders. In Excitatory Amino Acid Receptors, Larsen P, (ed.). Ellis Horwood: New York, 13-33.
26. Seo DW, Lopez-Meraz ML, Allen S, et al,. 2009. Contribution of a mitochondrial pathway to excitotoxic neuronal necrosis. J Neurosci Res 87: 2087-2094.
27. Stefanis L, Burke RE, Greene LA,. 1997. Apoptosis in neurodegenerative disorders. Curr Opin Neurol 10: 299-305.
28. Yu XY, An LJ,. 2002. A serum- and antioxidant-free primary culture of mouse cortical neurons for pharmacological screen and studies of neurotrophic and neuroprotective agents. Cel Mol Neurobiol 22: 197-206.
29. Yu XY, An LJ, Wang YQ, et al,. 2003a. Neuroprotective effect of Alpinia oxyphylla Miq. fruits against glutamate-induced apoptosis in cortical neurons. Toxicol Lett 144: 205-212.
30. Yu XY, Sun L, Luo XY, et al,. 2003b. Investigation of the neuronal death mode induced by glutamate treatment in serum-, antioxidant-free primary cultured cortical neurons. Dev Brain Res 145: 263-268.
31. Zhang J, Li L, Chen X, Zhang B, et al,. 2000. Effects of a traditional Chinese medicine, Qing Nao Yi Zhi Fang, on glutamate excitotoxicity in rat fetal cerebral neuronal cells in primary culture. Neurosci Lett 1: 21-24.
32. Zhou SL, Chen X, Gu XS, et al,. 2009. Achyranthes bidentata Blume extract protects cultured hippocampal neurons against glutamate-induced neurotoxicity. J Ethnopharmacol 122: 547-554.