메뉴 건너뛰기




Volumn 50, Issue 4, 2012, Pages 259-263

Central nervous system regeneration does not occur

Author keywords

central nervous system; central pattern generator; neurone theory; regeneration; spinal shock

Indexed keywords

CENTRAL NERVOUS SYSTEM; CENTRAL NERVOUS SYSTEM DISEASE; HUMAN; LOCOMOTION; MOTONEURON; NERVE CELL; NERVE CELL PLASTICITY; NERVE REGENERATION; NERVE SPROUTING; NONHUMAN; PARAPLEGIA; PRIORITY JOURNAL; REVIEW; SPINAL CORD; SPINAL CORD LESION; SPINAL CORD STIMULATION; SPINAL CORD TRANSSECTION; THEORY; TRAINING;

EID: 84859594040     PISSN: 13624393     EISSN: 14765624     Source Type: Journal    
DOI: 10.1038/sc.2011.132     Document Type: Review
Times cited : (45)

References (43)
  • 1
    • 0036915794 scopus 로고    scopus 로고
    • Repair of spinal cord injuries: Where are we, where are we going?
    • DOI 10.1038/sj.sc.3101328
    • Fawcett J. Repair of spinal cord injuries: where are we, where are we going? Spinal Cord 2002; 40: 615-623. (Pubitemid 36005843)
    • (2002) Spinal Cord , vol.40 , Issue.12 , pp. 615-623
    • Fawcett, J.1
  • 2
    • 15244344434 scopus 로고    scopus 로고
    • Corticospinal regeneration into lumbar grey matter correlates with locomotor recovery after complete spinal corel transection and repair with peripheral nerve grafts, fibroblast growth factor 1, fibrin glue, and spinal fusion
    • Tsai EC, Krassioukov AV, Tator CH. Corticospinal regeneration into lumbar grey matter correlates with locomotor recovery after complete spinal cord transection and repair with peripheral nerve grates, fibroblast growth factor 1, fibrin glue and spinal fusion. J Neurpathol Ex Neuro 2005; 64: 230-244. (Pubitemid 40389232)
    • (2005) Journal of Neuropathology and Experimental Neurology , vol.64 , Issue.3 , pp. 230-244
    • Tsai, E.C.1    Krassioukov, A.V.2    Tator, C.H.3
  • 3
    • 70350203996 scopus 로고    scopus 로고
    • Combined intrinsic and extrinsic neuronal mechanisms facilitate bridging axonal regeneration one year after spinal cord injury
    • Kadoya K, Tsukada S, Lu P, Coppola G, Geschwind D, Filbin M et al. Combined intrinsic and extrinsic neuronal mechanisms facilitate bridging axonal regeneration one year after spinal cord injury. Neuron 2009; 64: 165-172.
    • (2009) Neuron , vol.64 , pp. 165-172
    • Kadoya, K.1    Tsukada, S.2    Lu, P.3    Coppola, G.4    Geschwind, D.5    Filbin, M.6
  • 4
    • 0023410632 scopus 로고
    • Axonal regeneration and synapse formation in the superior colliculus by retinal ganglion cells in the adult rat
    • Vidal-Sanz M, Bray GM, Villegas-Perez MP, Thanos S, Aguayo AJ. Axonal regeneration and synapse formation in the superior colliculus by retinal ganglion cells in the adult rat. J Neurosci 1987; 7: 2894-2909.
    • (1987) J Neurosci , vol.7 , pp. 2894-2909
    • Vidal-Sanz, M.1    Bray, G.M.2    Villegas-Perez, M.P.3    Thanos, S.4    Aguayo, A.J.5
  • 5
    • 77956187905 scopus 로고    scopus 로고
    • PTEN depletion enhances the regenerative ability of adult corticospinal neurons
    • Lui K, Lu Y, Lee JK, Samara R, Willenberg R, Sears-Kraxberger I et al. PTEN depletion enhances the regenerative ability of adult corticospinal neurons. Nat Neurosci 2010; 13: 1075-1081.
    • (2010) Nat Neurosci , vol.13 , pp. 1075-1081
    • Lui, K.1    Lu, Y.2    Lee, J.K.3    Samara, R.4    Willenberg, R.5    Sears-Kraxberger, I.6
  • 6
    • 79959897174 scopus 로고    scopus 로고
    • Neuronal intrinsic mechanisms of axon regeneration
    • Liu K, Tedeschi A, Park KK, He Z. Neuronal intrinsic mechanisms of axon regeneration. Ann Rev Neurosoc 2011; 34: 131-152.
    • (2011) Ann Rev Neurosoc , vol.34 , pp. 131-152
    • Liu, K.1    Tedeschi, A.2    Park, K.K.3    He, Z.4
  • 7
    • 0036829585 scopus 로고    scopus 로고
    • Santiago Ramón y Cajal's concept of neuronal plasticity: The ambiguity lives on
    • DOI 10.1016/S0166-2236(02)02251-8, PII S0166223602022518
    • Stahnisch FW, Nitsch R. Santiago Ramon y Cajal's concept of neurological plasticity. Trends Neurosci 2002; 25: 589-591. (Pubitemid 35254183)
    • (2002) Trends in Neurosciences , vol.25 , Issue.11 , pp. 589-591
    • Stahnisch, F.W.1    Nitsch, R.2
  • 8
    • 79953331005 scopus 로고    scopus 로고
    • Neural plasticity and functional recovery of human central nervous system with special reference to spinal cord injury
    • Wang D, Sun T. Neural plasticity and functional recovery of human central nervous system with special reference to spinal cord injury. Spinal Cord 2011; 49: 486-492.
    • (2011) Spinal Cord , vol.49 , pp. 486-492
    • Wang, D.1    Sun, T.2
  • 9
    • 0002092792 scopus 로고
    • Plasticity of connections in the adult nervous system
    • Cotman CW (ed). Raven Press: New York
    • Merrill EG, Wall PD. Plasticity of connections in the adult nervous system. In: Cotman CW (ed). Neuronal Plasticity 1978. Raven Press: New York, 97-111.
    • (1978) Neuronal Plasticity , pp. 97-111
    • Merrill, E.G.1    Wall, P.D.2
  • 10
    • 0014665047 scopus 로고
    • Enlargement of spinal cord synapses after repetitive stimulation
    • Illis LS. Enlargement of spinal cord synapses after repetitive stimulation. Nature 1969; 223: 76-77.
    • (1969) Nature , vol.223 , pp. 76-77
    • Illis, L.S.1
  • 13
    • 0014167606 scopus 로고
    • The motor neuron surface and spinal shock
    • Williams D (ed). Butterworths: London
    • Illis LS. The motor neuron surface and spinal shock. In: Williams D (ed). Modern Trends in Neurology, vol. 4. 1967. Butterworths: London, pp 53-68.
    • (1967) Modern Trends in Neurology , vol.4 , pp. 53-68
    • Illis, L.S.1
  • 14
    • 11844272095 scopus 로고
    • Growth and plasticity in the nervous system
    • Young JZ. Growth and plasticity in the nervous system. Proc Roy Soc 1951; B139: 18-37.
    • (1951) Proc Roy Soc , vol.B139 , pp. 18-37
    • Young, J.Z.1
  • 17
    • 84907130459 scopus 로고
    • Staining neural end feet and mitochondria after post-chroming and carbowax embedding
    • Armstrong J, Richardson KC, Young JZ. Staining neural end feet and mitochondria after post-chroming and carbowax embedding. Stain Technol 1956; 31: 263-270.
    • (1956) Stain Technol , vol.31 , pp. 263-270
    • Armstrong, J.1    Richardson, K.C.2    Young, J.Z.3
  • 18
    • 0016185211 scopus 로고
    • Silver deposition in synaptic vesicles using the Armstrong-Stephens stain
    • Fitzsimons JTR, Illis LS, Mitchell J. Silver deposition in synaptic vesicles using the Armstrong-Stephens stain. Brain Res 1974; 72: 277-281.
    • (1974) Brain Res , vol.72 , pp. 277-281
    • Fitzsimons, J.T.R.1    Illis, L.S.2    Mitchell, J.3
  • 19
    • 0342979878 scopus 로고
    • Neuron size and neuron population density in the lumbosacral region of the cat's spinal cord
    • Aitken JT, Bridger JE. Neuron size and neuron population density in the lumbosacral region of the cat's spinal cord. J Anat 1961; 95: 38-53.
    • (1961) J Anat , vol.95 , pp. 38-53
    • Aitken, J.T.1    Bridger, J.E.2
  • 20
    • 12244308250 scopus 로고
    • Spinal cord synapses in the cat. The normal appearances by the light microscope
    • Illis LS. Spinal cord synapses in the cat. The normal appearances by the light microscope. Brain 1964; 87: 543-554.
    • (1964) Brain , vol.87 , pp. 543-554
    • Illis, L.S.1
  • 21
    • 70449178991 scopus 로고
    • Intraspinal sprouting of dorsal root axons Arch
    • Liu Cnchambers WW. Intraspinal sprouting of dorsal root axons Arch. Neurol Psychiat 1958; 79: 46-61.
    • (1958) Neurol Psychiat , vol.79 , pp. 46-61
    • Liu Cnchambers, W.W.1
  • 22
    • 0013879692 scopus 로고
    • Boutons termineaux and tri-ortho-cresyl phosphate toxicity
    • Illis LS, Patangia GN, Cavanagh JB. Boutons termineaux and tri-ortho-cresyl phosphate toxicity. Exp Neurol 1966; 14: 160-174.
    • (1966) Exp Neurol , vol.14 , pp. 160-174
    • Illis, L.S.1    Patangia, G.N.2    Cavanagh, J.B.3
  • 23
    • 0014531780 scopus 로고
    • Neuronal plasticity in the septal nuclei of the adult rat
    • Raisman G. Neuronal plasticity in the septal nuclei of the adult rat. Brain Res 1969; 14: 25-48.
    • (1969) Brain Res , vol.14 , pp. 25-48
    • Raisman, G.1
  • 24
    • 12244274706 scopus 로고
    • Spinal cord synapses in the cat: The reaction of boutons termineaux at the motoneuron surface to experimental denervation
    • Illis LS. Spinal cord synapses in the cat: the reaction of boutons termineaux at the motoneuron surface to experimental denervation. Brain 1964; 87: 55-572.
    • (1964) Brain , vol.87 , pp. 55-572
    • Illis, L.S.1
  • 25
    • 0015546209 scopus 로고
    • Experimental model of regeneration in the CNS. I Synaptic Changes
    • Illis LS. Experimental model of regeneration in the CNS. I Synaptic Changes Brain 1973; 96: 47-60.
    • (1973) Brain , vol.96 , pp. 47-60
    • Illis, L.S.1
  • 26
    • 0015546211 scopus 로고
    • Experimental model of regeneration in the CNS. II. The reaction of glia
    • Illis LS. Experimental model of regeneration in the CNS. II. The reaction of glia. Brain 1973; 96: 61-68.
    • (1973) Brain , vol.96 , pp. 61-68
    • Illis, L.S.1
  • 28
    • 0008216699 scopus 로고
    • Changes in spinal cord synapses and possible explanation for spinal shock
    • Illis LS. Changes in spinal cord synapses and possible explanation for spinal shock. Exp Neurol 1963; 8: 328-335.
    • (1963) Exp Neurol , vol.8 , pp. 328-335
    • Illis, L.S.1
  • 31
    • 6844221781 scopus 로고
    • Responses of the de-afferented spinal neurones to corticospinal impulses
    • Teasdell RD, Stavraky GW. Responses of the de-afferented spinal neurones to corticospinal impulses. J Neurophysiol 1953; 16: 367-375.
    • (1953) J Neurophysiol , vol.16 , pp. 367-375
    • Teasdell, R.D.1    Stavraky, G.W.2
  • 32
    • 0013525938 scopus 로고
    • Election microscopy of experimental degeneration in the avian optic tectum
    • Gray EG, Hamlyn LH. Election microscopy of experimental degeneration in the avian optic tectum. J Anat 1962; 96: 309-316.
    • (1962) J Anat , vol.96 , pp. 309-316
    • Gray, E.G.1    Hamlyn, L.H.2
  • 33
    • 0038470959 scopus 로고    scopus 로고
    • A promising therapeutic approach to spinal cord repair
    • Raisman G. A promising therapeutic approach to spinal cord repair. J R SocMed 2003; 96: 259-261. (Pubitemid 36714050)
    • (2003) Journal of the Royal Society of Medicine , vol.96 , Issue.6 , pp. 259-261
    • Raisman, G.1
  • 34
    • 0027231623 scopus 로고
    • Spinal shock: Possible role of receptor plasticity and non-synpatic transmission
    • Bach-Y-Rita P, Illis LS. Spinal shock: possible role of receptor plasticity and non-synpatic transmission. Paraplegia 1993; 31: 82-87.
    • (1993) Paraplegia , vol.31 , pp. 82-87
    • Bach-Y-Rita, P.1    Illis, L.S.2
  • 36
    • 0000063101 scopus 로고
    • Locomotion in the mesencephalic cat elicited by stimulation of the pyramids
    • Shik ML, Orlovski GN, Severin FV. Locomotion in the mesencephalic cat elicited by stimulation of the pyramids. Biophysics 1968; 13: 143-152.
    • (1968) Biophysics , vol.13 , pp. 143-152
    • Shik, M.L.1    Orlovski, G.N.2    Severin, F.V.3
  • 37
    • 0021873114 scopus 로고
    • Excitatory and inhibititory postsynaptic potentials in alpha motoneurons produced during fictive locomotion by stimulation of the mesencephalic locomotor region
    • Shefchyk SJ, Jordan LM. Excitatory and inhibititory postsynaptic potentials in alpha motoneurons produced during fictive locomotion by stimulation of the mesencephalic locomotor region. J Neurophsiol 1958; 53: 1345-1355.
    • (1958) J Neurophsiol , vol.53 , pp. 1345-1355
    • Shefchyk, S.J.1    Jordan, L.M.2
  • 38
    • 0015922677 scopus 로고
    • The locomotion of the acute spinal cat injected with clonidine I
    • Fossberg H, Grillner S. The locomotion of the acute spinal cat injected with clonidine I. V Brain Res 1973; 50: 184-186.
    • (1973) V Brain Res , vol.50 , pp. 184-186
    • Fossberg, H.1    Grillner, S.2
  • 39
    • 0027415043 scopus 로고
    • Noradrenergic agonists and locomotor training affect locomotor recovery after cord transection in adult cats
    • Barbeau H, Chan C, Rossignol S. Noradrenergic agonists and locomotor training effect locomotor recovery after cord transection in adult cats. Brain Res Bull 1993; 30: 387-393. (Pubitemid 23072748)
    • (1993) Brain Research Bulletin , vol.30 , Issue.3-4 , pp. 387-393
    • Barbeau, H.1    Chau, C.2    Rossignol, S.3
  • 40
    • 0026518160 scopus 로고
    • Laufband locomotion with body weight support improved walking in persons with severe spinal cord injuries
    • Wernig A, Muller S. Laufband locomotion with body weight support improved walking in persons with severe spinal cord injuries. Paraplegia 1992; 30: 229-238.
    • (1992) Paraplegia , vol.30 , pp. 229-238
    • Wernig, A.1    Muller, S.2
  • 41
    • 0028171623 scopus 로고
    • Locomotor activity in spinal man
    • DOI 10.1016/S0140-6736(94)90751-X
    • Dietz V, Colombo G, Jensen L. Locomotor activity in spinal man. Lancet 1994; 344: 1260-1263. (Pubitemid 24334682)
    • (1994) Lancet , vol.344 , Issue.8932 , pp. 1260-1263
    • Dietz, V.1    Colombo, G.2    Jensen, L.3
  • 43
    • 84970053636 scopus 로고
    • Recovery in the CNS and the experimental background of central functional simulation in spinal cord dysfunction
    • Illis LS (ed). Chapter 1 Oxford University Press: Oxford
    • Illis LS. Recovery in the CNS and the experimental background of central functional simulation in spinal cord dysfunction. In: Illis LS (ed). Chapter 1 in Spinal Cord Dysfunction. Oxford University Press: Oxford, 1992, 9-37.
    • (1992) Spinal Cord Dysfunction , pp. 9-37
    • Illis, L.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.