A promising therapeutic approach to spinal cord repair

Journal of the Royal Society of Medicine

Volumn 96, Issue 6, 2003, Pages 259-261

  Raisman, Geoffrey ^a  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELL TRANSPLANTATION; EDITORIAL; GLIA; HUMAN; NERVE CELL PLASTICITY; NERVE FIBER GROWTH; NERVE FIBER REGENERATION; NERVE INJURY; NERVE REGENERATION; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; OLFACTORY ENSHEATHING CELL; OLFACTORY NERVOUS SYSTEM; SPINAL CORD INJURY;

EID: 0038470959     PISSN: 01410768     EISSN: None     Source Type: Journal    
DOI: 10.1258/jrsm.96.6.259     Document Type: Editorial

References (23)

1. Cajal SR. Studies on Vertebrate Neurogenesis. Springfield: Charles C Thomas, 1960
2. Cadelli DS, Bandtlow CE, Schwab ME. Oligodendrocyte-associated and myelin-associated inhibitors of neurite outgrowth - their involvement in the lack of CNS regeneration. Exp Neurol 1992;115:189-92
3. Cajal SR. Degeneration and Regeneration of the Nervous System. New York: Hafner, 1928
4. Raisman G. Neuronal plasticity in the septal nuclei of the adult rat. Brain Res 1969;14:25-48
5. Merzenich MM, Kaas JH, Wall J, Nelson RJ, Sur M, Felleman D. Topographic reorganization of somatosensory cortical areas 3B and 1 in adult monkeys following restricted deafferentation. Neuroscience 1983;8:33-55
6. Florence SL, Kaas JH. Large-scale reorganization at multiple levels of the somatosensory pathway follows therapeutic amputation of the hand in monkeys. J Neurosci 1995;15:8083-95
7. Schwab ME, Caroni P. Oligodendrocytes and CNS myelin are nonpermissive substrates for neurite growth and fibroblast spreading in vitro. J Neurosci 1988;8:2381-93
8. Burrill JD, Easter Jr SS. The first retinal axons and their microenvironment in zebrafish: cryptic pioneers and the pretract. J Neurosci 1995;15:2935-47
9. Suzuki M, Raisman G. The glial framework of central white matter tracts: segmented rows of contiguous interfascicular oligodendrocytes and solitary astrocytes give rise to a continuous meshwork of transverse and longitudinal processes in the adult rat fimbria. Glia 1992;6:222-35
10. Tessier-Lavigne M, Goodman CS. The molecular biology of axon guidance. Science 1996;274:1123-33
11. Suzuki M, Raisman G. Multifocal pattern of postnatal development of the macroglial framework of the rat fimbria. Glia 1994;12:294-308
12. Davies SJA, Field PM, Raisman G. Regeneration of cut adult axons fails even in the presence of continuous aligned glial pathways. Exp Neurol 1996;142:203-16
13. Vidal-Sanz M, Bray GM, Villegas-Pérez MP, Thanos S, Aguayo AJ. Axonal regeneration and synapse formation in the superior colliculus by retinal ganglion cells in the adult rat. J Neurosci 1987;7:2894-909
14. Bernstein-Goral H, Bregman BS. Axotomized rubrospinal neurons rescued by fetal spinal cord transplants maintain axon collaterals to rostral CNS targets. Exp Neurol 1997;148:13-25
15. Xu XM, Guénard V, Kleitman N, Bunge MB. Axonal regeneration into Schwann cell-seeded guidance channels grafted into transected adult rat spinal cord. J Comp Neurol 1995;351:145-60
16. Ramón-Cueto A, Cordero MI, Santos-Benito FF, Avila J. Functional recovery of paraplegic rats and motor axon regeneration in their spinal cords by olfactory ensheathing glia. Neuron 2000;25: 425-35
17. Verdu E, Garcia-Alias G, Fores J, et al. Effects of ensheathing cells transplanted into photochemically damaged spinal cord. NeuroRep 2001;12:2303-9
18. Altman J. Autoradiographic and histological studies of postnatal neurogenesis. IV. Cell proliferation and migration in the anterior fore-brain, with special reference to persisting neurogenesis in the olfactory bulb. J Comp Neurol 1969;137:433-58
19. Graziadei PPC, Montigraziadei GA. Neurogenesis and neuron regeneration in the olfactory system of mammals. I. Morphological aspects of differentiation and structural organization of the olfactory sensory neurons. J Neurocytol 1979;8:1-18
20. Raisman G. Specialized neuroglial arrangement may explain the capacity of vomeronasal axons to reinnervate central neurons. Neuroscience 1985;4:237-54
21. Ramón-Cueto A, Nieto-Sampedro M. Glial cells from adult rat olfactory bulb: immunocytochemical properties of pure cultures of ensheathing cells. Neuroscience 1992;47:213-20
22. Li Y, Field PM, Raisman G. Regeneration of adult rat corticospinal axons induced by transplanted olfactory ensheathing cells. J Neurosci 1998;18:10514-24
23. Li Y, Decherchi P, Raisman G. Transplantation of olfactory ensheathing cells into spinal cord lesions restores breathing and climbing. J Neurosci 2003;23:727-31