Statistical considerations of optimal study design for human plasma proteomics and biomarker discovery

Journal of Proteome Research

Volumn 11, Issue 4, 2012, Pages 2103-2113

  Zhou, Cong ^a   Simpson, Kathryn L ^a   Lancashire, Lee J ^a   Walker, Michael J ^a   Dawson, Martin J ^a   Unwin, Richard D ^a   Rembielak, Agata ^a   Price, Patricia ^a   West, Catharine ^a   Dive, Caroline ^a   Whetton, Anthony D ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

biomarkers; mass spectrometry; plasma proteomics; power analysis

Indexed keywords

BIOLOGICAL MARKER; PEROXIREDOXIN 2; PLASMA PROTEIN;

ARTICLE; CANCER PATIENT; CELL FRACTIONATION; CONTROLLED STUDY; HUMAN; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; PANCREAS CANCER; POST HOC ANALYSIS; POWER ANALYSIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEOMICS; REVERSED PHASE LIQUID CHROMATOGRAPHY; SAMPLE SIZE; STATISTICAL ANALYSIS; STUDY DESIGN; VARIANCE; WESTERN BLOTTING;

BLOOD PROTEINS; CASE-CONTROL STUDIES; FACTOR XIII; HUMANS; NEOPLASM PROTEINS; PANCREATIC NEOPLASMS; PEROXIREDOXINS; PROTEOME; PROTEOMICS; REPRODUCIBILITY OF RESULTS; STATISTICS AS TOPIC; TUMOR MARKERS, BIOLOGICAL;

EID: 84859594013     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr200636x     Document Type: Article

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