An efficient and safe method for the multigram synthesis of trans -2-(trifluoromethyl)cyclopropylamine

Synthesis

Volumn 44, Issue 8, 2012, Pages 1152-1154

  Yarmolchuk, Vladimir S ^a,b   Bezdudny, Andrii V ^a   Tolmacheva, Nataliya A ^a   Lukin, Oleg ^b   Boyko, Alexander N ^b   Chekotylo, Alexey ^b   Tolmachev, Andrei A ^a,b   Mykhailiuk, Pavel K ^a,b  

^a ENAMINE LTD   (Ukraine)

^b TARAS SHEVCHENKO NATIONAL UNIVERSITY OF KYIV   (Ukraine)

Author keywords

amines; Corey Chaykovsky cyclopropanation; cyclopropyl group; fluorine; trifluoromethyl group

Indexed keywords

COREY-CHAYKOVSKY REACTION; CYCLOPROPANATION; CYCLOPROPANE RING; CYCLOPROPYL GROUP; METHOXYMETHYL; MULTIGRAM SYNTHESIS; TRIFLUOROMETHYL; TRIFLUOROMETHYL GROUP;

AMINES; FLUORINE; PROPANE;

AMIDES;

2 (TRIFLUOROMETHYL)CYCLOPROPYLAMINE; 4,4,4 TRIFLUOROBUT 2 ENOIC ACID ETHYL ESTER; CYCLOPROPANE; ESTER DERIVATIVE; PROPYLAMINE; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL REACTION; CHEMICAL STRUCTURE; COREY CHAYKOVSKY REACTION; CYCLOPROPANATION; FLUORINE NUCLEAR MAGNETIC RESONANCE; LIQUID CHROMATOGRAPHY; PROTON NUCLEAR MAGNETIC RESONANCE; SYNTHESIS; TANDEM MASS SPECTROMETRY; THIN LAYER CHROMATOGRAPHY;

EID: 84859562912     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0031-1289711     Document Type: Article

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