Monitoring the glioma tropism of bone marrowderived progenitor cells by 2-photon laser scanning microscopy and positron emission tomography

Neuro-Oncology

Volumn 14, Issue 4, 2012, Pages 471-481

  Hasenbach, Kathy ^a,c   Wiehr, Stefan ^d   Herrmann, Caroline ^a,d   Mannheim, Julia ^d   Cay, Funda ^c   Von Kürthy, Gabriele ^a,c   Bolmont, Tristan ^b   Grathwohl, Stefan A ^b   Weller, Michael ^c   Lengerke, Claudia ^e   Pichler, Bernd J ^d   Tabatabai, Ghazaleh ^a,c,d  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^d UNIVERSITY OF TÜBINGEN   (Germany)

^e UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

Author keywords

2 photon laser scanning microscopy; adult stem cells; cell based therapy; cellular trafficking; Glioma; positron emission tomography

Indexed keywords

THYMIDINE KINASE 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOLUMINESCENCE; CELL HOMING; CELL MIGRATION; CONTROLLED STUDY; FLUORESCENCE; GLIOMA; HEMATOPOIETIC STEM CELL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; HUMAN CELL; IMAGE ANALYSIS; LASER MICROSCOPY; LIVER; LUNG; MOUSE; MUSCLE; NONHUMAN; PHOTON; POSITRON EMISSION TOMOGRAPHY; SPLEEN; TROPISM;

ANIMALS; CELL LINE, TUMOR; CELL MOVEMENT; GLIOMA; HEMATOPOIETIC STEM CELLS; HUMANS; MAGNETIC RESONANCE IMAGING; MICE; MICROSCOPY, CONFOCAL; POSITRON-EMISSION TOMOGRAPHY; TISSUE THERAPY;

EID: 84859554885     PISSN: 15228517     EISSN: 15235866     Source Type: Journal    
DOI: 10.1093/neuonc/nor228     Document Type: Article

References (30)

1. Stupp R, Mason WP, van den Bent MJ, et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med. 2005;352(10):987-996. (Pubitemid 40349501)
2. Ohgaki H. Epidemiology of brain tumors. Methods Mol Biol. 2009;472:323-342.
3. Ohgaki H, Kleihues P. Population-based studies on incidence, survival rates, and genetic alterations in astrocytic and oligodendroglial gliomas. J Neuropathol Exp Neurol. 2005;64(6):479-489. (Pubitemid 40781150)
4. Furnari FB, Fenton T, Bachoo RM, et al. Malignant astrocytic glioma: genetics, biology, and paths to treatment. Genes Dev. 2007;21(21):2683-2710. (Pubitemid 350070717)
5. Aboody KS, Brown A, Rainov NG, et al. Neural stem cells display extensive tropism for pathology in adult brain: evidence from intracranial gliomas. Proc Natl Acad Sci USA. 2000;97(23):12846-12851.
6. Lin D, Najbauer J, Salvaterra PM, et al. Novel method for visualizing and modeling the spatial distribution of neural stem cells within intracranial glioma. Neuroimage. 2007;37(suppl 1):S18-S26. (Pubitemid 47239428)
7. Ehtesham M, Kabos P, Kabosova A, Neuman T, Black KL, Yu JS. The use of interleukin 12-secreting neural stem cells for the treatment of intracranial glioma. Cancer Res. 2002;62(20):5657-5663. (Pubitemid 35204717)
8. Nakamizo A, Marini F, Amano T, et al. Human bone marrow-derived mesenchymal stem cells in the treatment of gliomas. Cancer Res. 2005;65(8):3307-3318. (Pubitemid 40524615)
9. Tabatabai G, Bahr O, Mohle R, et al. Lessons from the bone marrow: how malignant glioma cells attract adult haematopoietic progenitor cells. Brain. 2005;128(pt 9):2200-2211. (Pubitemid 41253286)
10. Tabatabai G, Frank B, Mohle R, Weller M, Wick W. Irradiation and hypoxia promote homing of haematopoietic progenitor cells towards gliomas by TGF-beta-dependent HIF-1alpha-mediated induction of CXCL12. Brain. 2006;129(pt 9):2426-2435. (Pubitemid 44522127)
11. Tabatabai G, Herrmann C, von Kurthy G, et al. VEGF-dependent induction of CD62E on endothelial cells mediates glioma tropism of adult haematopoietic progenitor cells. Brain. 2008;131(pt 10):2579-2595.
12. Friese MA, Platten M, Lutz SZ, et al. MICA/NKG2D-mediated immunogene therapy of experimental gliomas. Cancer Res. 2003;63(24): 8996-9006. (Pubitemid 38064081)
13. Weller M, Rieger J, Grimmel C, et al. Predicting chemoresistance in human malignant glioma cells: the role of molecular genetic analyses. Int J Cancer. 1998;79(6):640-644. (Pubitemid 28549478)
14. Rieger J, Lemke D, Maurer G, et al. Enzastaurin-induced apoptosis in glioma cells is caspase-dependent and inhibited by BCL-XL. J Neurochem. 2008;106(6):2436-2448.
15. Bautz F, Denzlinger C, Kanz L, Mohle R. Chemotaxis and transendothelial migration of CD34(+) hematopoietic progenitor cells induced by the inflammatory mediator leukotriene D4 are mediated by the 7-transmembrane receptor CysLT1. Blood. 2001;97(11):3433-3440.
16. Berenson RJ, Andrews RG, Bensinger WI, et al. Antigen CD34+ marrow cells engraft lethally irradiated baboons. J Clin Invest. 1988;81(3):951-955. (Pubitemid 18079751)
17. Andrews RG, Singer JW, Bernstein ID. Monoclonal antibody 12-8 recognizes a 115-kd molecule present on both unipotent and multipotent hematopoietic colony-forming cells and their precursors. Blood. 1986;67(3):842-845. (Pubitemid 16130285)
18. Gao Z, Fackler MJ, Leung W, et al. Human CD34+ cell preparations contain over 100-fold greater NOD/SCID mouse engrafting capacity than do CD34-cell preparations. Exp Hematol. 2001;29(7): 910-921. (Pubitemid 32600924)
19. Lassailly F, Griessinger E, Bonnet D. "Microenvironmental contaminations" induced by fluorescent lipophilic dyes used for noninvasive in vitro and in vivo cell tracking. Blood. 2010;115(26):5347-5354.
20. Cao F, Lin S, Xie X, et al. In vivo visualization of embryonic stem cell survival, proliferation, and migration after cardiac delivery. Circulation. 2006;113(7):1005-1014. (Pubitemid 43879476)
21. Tabatabai G, Hasenbach K, Herrmann C, et al. Glioma tropism of lentivirally transduced hematopoietic progenitor cells. Int J Oncol. 2010;36(6):1409-1417.
22. Helmchen F, Denk W. Deep tissue two-photon microscopy. Nat Methods. 2005;2(12):932-940. (Pubitemid 43108729)
23. Denk W, Strickler JH, Webb WW. Two-photon laser scanning fluorescence microscopy. Science. 1990;248(4951):73-76.
24. Judenhofer MS, Wehrl HF, Newport DF, et al. Simultaneous PET-MRI: a new approach for functional and morphological imaging. Nat Med. 2008;14(4):459-465. (Pubitemid 351499385)
25. Egea V, von Baumgarten L, Schichor C, et al. TNF-alpha respecifies human mesenchymal stem cells to a neural fate and promotes migration toward experimental glioma. Cell Death Differ. 2011;18(5):853-863.
26. Ahrens ET, Flores R, Xu H, Morel PA. In vivo imaging platform for tracking immunotherapeutic cells. Nat Biotechnol. 2005;23(8): 983-987. (Pubitemid 41114032)
27. Nohroudi K, Arnhold S, Berhorn T, Addicks K, Hoehn M, Himmelreich U. In vivo MRI stem cell tracking requires balancing of detection limit and cell viability. Cell Transplant. 2010;19(4):431-441.
28. Schafer R, Kehlbach R, Muller M, et al. Labeling of human mesenchymal stromal cells with superparamagnetic iron oxide leads to a decrease in migration capacity and colony formation ability. Cytotherapy. 2009;11(1):68-78.
29. Yaghoubi SS, Jensen MC, Satyamurthy N, et al. Noninvasive detection of therapeutic cytolytic T cells with 18F-FHBG PET in a patient with glioma. Nat Clin Pract Oncol. 2009;6(1):53-58.
30. Brix G, Lechel U, Glatting G, et al. Radiation exposure of patients undergoing whole-body dual-modality 18F-FDG PET/CT examinations. J Nucl Med. 2005;46(4):608-613. (Pubitemid 41716405)