Histamine via the histamine H 2-receptor reduces α-CD3-induced interferon-γ synthesis in murine CD4 + T cells in an indirect manner

Journal of Interferon and Cytokine Research

Volumn 32, Issue 4, 2012, Pages 185-190

  Vauth, Marcus ^a   Möhner, Desirée ^a   Beermann, Silke ^a   Seifert, Roland ^a   Neumann, Detlef ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; HISTAMINE; HISTAMINE H2 RECEPTOR;

ANIMAL CELL; ARTICLE; CD3+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SPLEEN CELL;

ANIMALS; ANTIGENS, CD3; CD4-POSITIVE T-LYMPHOCYTES; CULTURE MEDIA, CONDITIONED; FEMALE; HISTAMINE; INTERFERON-GAMMA; INTERLEUKIN-10; MICE; MICE, INBRED C57BL; RECEPTORS, HISTAMINE H2; SPLEEN; TRANSFORMING GROWTH FACTOR BETA;

MURINAE;

EID: 84859518920     PISSN: 10799907     EISSN: 15577465     Source Type: Journal    
DOI: 10.1089/jir.2011.0082     Document Type: Article

References (16)

1. Bakker RA. 2004. Histamine H3-receptor isoforms. Inflamm Res 53:509-516.
2. Bakker RA, Timmerman H, Leurs R. 2002. Histamine receptors: specific ligands, receptor biochemistry, and signal transduction. Clin Allergy Immunol 17:27-64.
3. Carlsson R, Dohlsten M, Sjögren HO. 1985. Histamine modulates the production of interferon-gamma and interleukin-2 by mitogen-activated human mononuclear blood cells. Cell Immunol 96:104-112. (Pubitemid 16229615)
4. Huang J, Thurmond R. 2008. The new biology of histamine receptors. Curr Allergy Asthma Rep 8:21-27. (Pubitemid 351459689)
5. Ichikawa A, Sugimoto Y, Tanaka S. 2010. Molecular biology of histidine decarboxylase and prostaglandin receptors. Proc Jpn Acad Ser B Phys Biol Sci 86:848-866.
6. Jelinek I, László V, Buzás E, Pállinger E, Hangya B, Horváth Z, Falus A. 2007. Increased antigen presentation and Th1 polarization in genetically histamine-free mice. Int Immunol 19:51-58. (Pubitemid 46017887)
7. Jutel M, Akdis M, Akdis CA. 2009. Histamine, histamine receptors and their role in immune pathology. Clin Exp Allergy 39:1786-1800.
8. Jutel M, Watanabe T, Klunker S, Akdis M, Thomet O, Malolepszy J, Zak-Nejmark T, Koga R, Kobayashi T, Blaser K, Akdis C. 2001. Histamine regulates T-cell and antibody responses by differential expression of H1 and H2 receptors. Nature 413:420-425. (Pubitemid 32928596)
9. Kelm M, Feelisch M, Deussen A, Schrader J, Strauer BE. 1991. The role of nitric oxide in the control of coronary vascular tone in relation to partial oxygen pressure, perfusion pressure and flow. J Cardiovasc Pharmacol 17:95-99.
10. Koncz A, Pasztoi M, Mazan M, Fazakas F, Buzas E, Falus A, Nagy G. 2007. Nitric oxide mediates T cell cytokine production and signal transduction in histidine decarboxylase knockout mice. J Immunol 179:6613-6619.
11. Masaki T, Yoshimatsu H. 2010. Neuronal histamine and its receptors: implication of the pharmacological treatment of obesity. Curr Med Chem 17:4587-4592.
12. 2-receptor antagonists. Methods Find Exp Clin Pharmacol 11 Suppl 1:87-95.
13. 1 is required for TCR-mediated p38 MAPK activation and optimal IFN-gamma production in mice. J Clin Invest 117:3507-3518.
14. Osna N, Elliott K, Khan MM. 2001. The effects of histamine on interferon gamma production are dependent on the stimulatory signals. Int Immunopharmacol 1:135-145. (Pubitemid 32193608)
15. Schubert ML, Peura DA. 2008. Control of gastric acid secretion in health and disease. Gastroenterology 134:1842-1860. (Pubitemid 351783299)
16. 4 receptors in allergic inflammation: the search for new antihistamines. Nat Rev Drug Discov 7:41-53.