메뉴 건너뛰기




Volumn 77, Issue 3, 2012, Pages 188-195

Pumping iron: Revisiting risks, benefits and strategies in treatment of iron deficiency in end-stage renal disease

Author keywords

Anemia of CKD; End stage renal disease; Intravenous iron; Iron deficiency

Indexed keywords

ANTIANEMIC AGENT; FERRIC GLUCONATE; FERRIC HYDROXIDE SUCROSE; FERUMOXYTOL; IRON; IRON DEXTRAN;

EID: 84859514152     PISSN: 03010430     EISSN: None     Source Type: Journal    
DOI: 10.5414/CN107266     Document Type: Article
Times cited : (13)

References (49)
  • 1
    • 33646188352 scopus 로고    scopus 로고
    • Executive Summary
    • KDOQI Clinical Practice Guidelines and Clinical Practice Recommendations for Anemia in Chronic Kidney Disease
    • KDOQI Clinical Practice Guidelines and Clinical Practice Recommendations for Anemia in Chronic Kidney Disease. Executive Summary. Am J Kidney Dis. 2006; 47 (Suppl 3): S11-S145.
    • (2006) Am J Kidney Dis , Issue.SUPPL. 3
  • 2
    • 33846690885 scopus 로고    scopus 로고
    • The fascinating but deceptive ferritin: to measure it or not to measure it in chronic kidney disease?
    • Kalantar-Zadeh K, Lee GH. The fascinating but deceptive ferritin: to measure it or not to measure it in chronic kidney disease? Clin J Am Soc Nephrol. 2006; 1 (Suppl 1): S9-S18.
    • (2006) Clin J Am Soc Nephrol , vol.1 , Issue.SUPPL. 1
    • Kalantar-Zadeh, K.1    Lee, G.H.2
  • 3
    • 0032873161 scopus 로고    scopus 로고
    • Beneficial effects of adopting an aggressive intravenous iron policy in a hemodialysis unit
    • Macdougall IC, Chandler G, Elston O, Harchowal J. Beneficial effects of adopting an aggressive intravenous iron policy in a hemodialysis unit. Am J Kidney Dis. 1999; 34 (Suppl 2): S40-S46.
    • (1999) Am J Kidney Dis , vol.34 , Issue.SUPPL. 2
    • Macdougall, I.C.1    Chandler, G.2    Elston, O.3    Harchowal, J.4
  • 4
    • 33947212276 scopus 로고    scopus 로고
    • DRIVE Study Group Ferric gluconate is highly efficacious in anemic hemodialysis patients with high serum ferritin and low transferrin saturation: results of the Dialysis Patients' Response to IV Iron with Elevated Ferritin (DRIVE) Study
    • Coyne DW, Kapoian T, Suki W, Singh AK, Moran JE, Dahl NV, Rizkala AR; DRIVE Study Group. Ferric gluconate is highly efficacious in anemic hemodialysis patients with high serum ferritin and low transferrin saturation: results of the Dialysis Patients' Response to IV Iron with Elevated Ferritin (DRIVE) Study. J Am Soc Nephrol. 2007; 18: 975-984.
    • (2007) J Am Soc Nephrol , vol.18 , pp. 975-984
    • Coyne, D.W.1    Kapoian, T.2    Suki, W.3    Singh, A.K.4    Moran, J.E.5    Dahl, N.V.6    Rizkala, A.R.7
  • 7
    • 60349120822 scopus 로고    scopus 로고
    • Intravenous iron versus erythropoiesis-stimulating agents: friends or foes in treating chronic kidney disease anemia?
    • Kalantar-Zadeh K, Streja E, Miller JE, Nissenson AR. Intravenous iron versus erythropoiesis-stimulating agents: friends or foes in treating chronic kidney disease anemia? Adv Chronic Kidney Dis. 2009; 16: 143-151.
    • (2009) Adv Chronic Kidney Dis , vol.16 , pp. 143-151
    • Kalantar-Zadeh, K.1    Streja, E.2    Miller, J.E.3    Nissenson, A.R.4
  • 8
    • 80052437806 scopus 로고    scopus 로고
    • The role of erythropoiesis stimulating agents and intravenous (IV) iron in the cardio renal anemia syndrome
    • Silverberg DS. The role of erythropoiesis stimulating agents and intravenous (IV) iron in the cardio renal anemia syndrome. Heart Fail Rev. 2010; 16: 609-614.
    • (2010) Heart Fail Rev , vol.16 , pp. 609-614
    • Silverberg, D.S.1
  • 9
    • 79951709585 scopus 로고    scopus 로고
    • The effect of iron and erythropoietin treatment on the A1C of patients with diabetes and chronic kidney disease
    • Ng JM, Cooke M, Bhandari S, Atkin SL, Kilpatrick ES. The effect of iron and erythropoietin treatment on the A1C of patients with diabetes and chronic kidney disease. Diabetes Care. 2010; 33: 2310-2313.
    • (2010) Diabetes Care , vol.33 , pp. 2310-2313
    • Ng, J.M.1    Cooke, M.2    Bhandari, S.3    Atkin, S.L.4    Kilpatrick, E.S.5
  • 10
    • 35549010259 scopus 로고    scopus 로고
    • Nonhematological benefits of iron
    • Agarwal R. Nonhematological benefits of iron. Am J Nephrol. 2007; 27: 565-571.
    • (2007) Am J Nephrol , vol.27 , pp. 565-571
    • Agarwal, R.1
  • 11
    • 65349182361 scopus 로고    scopus 로고
    • Safety issues with intravenous iron products in the management of anemia in chronickidney disease
    • Hayat A. Safety issues with intravenous iron products in the management of anemia in chronickidney disease. Clin Med Res. 2008; 6: 93-102.
    • (2008) Clin Med Res , vol.6 , pp. 93-102
    • Hayat, A.1
  • 12
    • 48149115054 scopus 로고    scopus 로고
    • The comparative safety of various intravenous iron preparations in chronic kidney disease patients
    • Anirban G, Kohli HS, Jha V, Gupta KL, Sakhuja V. The comparative safety of various intravenous iron preparations in chronic kidney disease patients. Ren Fail. 2008; 30: 629-638.
    • (2008) Ren Fail , vol.30 , pp. 629-638
    • Anirban, G.1    Kohli, H.S.2    Jha, V.3    Gupta, K.L.4    Sakhuja, V.5
  • 13
    • 0036896348 scopus 로고    scopus 로고
    • Iron sucrose: the oldest iron therapy becomes new
    • Yee J, Besarab A. Iron sucrose: the oldest iron therapy becomes new. Am J Kidney Dis. 2002; 40: 1111-1121.
    • (2002) Am J Kidney Dis , vol.40 , pp. 1111-1121
    • Yee, J.1    Besarab, A.2
  • 14
    • 0031949458 scopus 로고    scopus 로고
    • Neutrophil impairment associated with iron therapy in hemodialysis patients with functional iron deficiency
    • Patruta SI, Edlinger R, Sunder-Plassmann G, Hörl WH. Neutrophil impairment associated with iron therapy in hemodialysis patients with functional iron deficiency. J Am Soc Nephrol. 1998; 9: 655-663.
    • (1998) J Am Soc Nephrol , vol.9 , pp. 655-663
    • Patruta, S.I.1    Edlinger, R.2    Sunder-Plassmann, G.3    Hörl, W.H.4
  • 16
    • 0035985424 scopus 로고    scopus 로고
    • Intravenous iron administration does not significantly increase the risk of bacteremia in chronic hemodialysis patients
    • Hoen B, Paul-Dauphin A, Kessler M. Intravenous iron administration does not significantly increase the risk of bacteremia in chronic hemodialysis patients. Clin Nephrol. 2002; 57: 457-461.
    • (2002) Clin Nephrol , vol.57 , pp. 457-461
    • Hoen, B.1    Paul-Dauphin, A.2    Kessler, M.3
  • 17
    • 61649124758 scopus 로고    scopus 로고
    • Lipid peroxidation products formation with various intravenous iron preparations in chronic kidney disease
    • Ganguli A, Kohli HS, Khullar M, Lal Gupta K, Jha V, Sakhuja V. Lipid peroxidation products formation with various intravenous iron preparations in chronic kidney disease. Ren Fail. 2009; 31: 106-110.
    • (2009) Ren Fail , vol.31 , pp. 106-110
    • Ganguli, A.1    Kohli, H.S.2    Khullar, M.3    Lal Gupta, K.4    Jha, V.5    Sakhuja, V.6
  • 18
    • 24044540417 scopus 로고    scopus 로고
    • Iron, oxidative stress and human health
    • Puntarulo S. Iron, oxidative stress and human health. Mol Aspects Med. 2005; 26: 299-312.
    • (2005) Mol Aspects Med , vol.26 , pp. 299-312
    • Puntarulo, S.1
  • 19
    • 33645508160 scopus 로고    scopus 로고
    • Proinflammatory effects of iron sucrose in chronic kidney disease
    • Agarwal R. Proinflammatory effects of iron sucrose in chronic kidney disease. Kidney Int. 2006; 69: 1259-1263.
    • (2006) Kidney Int , vol.69 , pp. 1259-1263
    • Agarwal, R.1
  • 20
    • 0036375278 scopus 로고    scopus 로고
    • Importance of serum ferritin levels in patients with renal failure
    • Gülçelik NE, Kayataş M. Importance of serum ferritin levels in patients with renal failure. Nephron. 2002; 92: 230-231.
    • (2002) Nephron , vol.92 , pp. 230-231
    • Gülçelik, N.E.1    Kayataş, M.2
  • 21
    • 34548178727 scopus 로고    scopus 로고
    • Iron sucrose causes greater proteinuria than ferric gluconate in non-dialysis chronic kidney disease
    • Agarwal R, Rizkala AR, Kaskas MO, Minasian R, Trout JR. Iron sucrose causes greater proteinuria than ferric gluconate in non-dialysis chronic kidney disease. Kidney Int. 2007; 72: 638-642.
    • (2007) Kidney Int , vol.72 , pp. 638-642
    • Agarwal, R.1    Rizkala, A.R.2    Kaskas, M.O.3    Minasian, R.4    Trout, J.R.5
  • 22
    • 2442677622 scopus 로고    scopus 로고
    • Oxidative stress and renal injury with intravenous iron in patients with chronic kidney disease
    • Agarwal R, Vasavada N, Sachs NG, Chase S. Oxidative stress and renal injury with intravenous iron in patients with chronic kidney disease. Kidney Int. 2004; 65: 2279-2289.
    • (2004) Kidney Int , vol.65 , pp. 2279-2289
    • Agarwal, R.1    Vasavada, N.2    Sachs, N.G.3    Chase, S.4
  • 23
    • 71849099443 scopus 로고    scopus 로고
    • Fanconi syndrome and CKD in a patient with paroxysmal nocturnal hemoglobinuria and hemosiderosis
    • Hsiao PJ, Wang SC, Wen MC, Diang LK, Lin SH. Fanconi syndrome and CKD in a patient with paroxysmal nocturnal hemoglobinuria and hemosiderosis. Am J Kidney Dis. 2010; 55: e1-e5.
    • (2010) Am J Kidney Dis , vol.55
    • Hsiao, P.J.1    Wang, S.C.2    Wen, M.C.3    Diang, L.K.4    Lin, S.H.5
  • 24
  • 25
    • 64549093824 scopus 로고    scopus 로고
    • Iron polymaltose-induced FGF23 elevation complicated by hypophosphataemic osteomalacia
    • Schouten BJ, Doogue MP, Soule SG, Hunt PJ. Iron polymaltose-induced FGF23 elevation complicated by hypophosphataemic osteomalacia. Ann Clin Biochem. 2009; 46: 167-169.
    • (2009) Ann Clin Biochem , vol.46 , pp. 167-169
    • Schouten, B.J.1    Doogue, M.P.2    Soule, S.G.3    Hunt, P.J.4
  • 26
    • 68849127439 scopus 로고    scopus 로고
    • Hypophosphatemia induced by intravenous administration of saccharated ferric oxide: another form of FGF23-related hypophosphatemia
    • Shimizu Y, Tada Y, Yamauchi M, Okamoto T, Suzuki H, Ito N, Fukumoto S, Sugimoto T, Fujita T. Hypophosphatemia induced by intravenous administration of saccharated ferric oxide: another form of FGF23-related hypophosphatemia. Bone. 2009; 45: 814-816.
    • (2009) Bone , vol.45 , pp. 814-816
    • Shimizu, Y.1    Tada, Y.2    Yamauchi, M.3    Okamoto, T.4    Suzuki, H.5    Ito, N.6    Fukumoto, S.7    Sugimoto, T.8    Fujita, T.9
  • 28
    • 0036836133 scopus 로고    scopus 로고
    • Serum ferritin levels and early prognosis of stroke
    • Erdemoglu AK, Ozbakir S. Serum ferritin levels and early prognosis of stroke. Eur J Neurol. 2002; 9: 633-637.
    • (2002) Eur J Neurol , vol.9 , pp. 633-637
    • Erdemoglu, A.K.1    Ozbakir, S.2
  • 29
    • 54349090164 scopus 로고    scopus 로고
    • Intravenous versus oral iron supplementation for the treatment of anemia in CKD: systematic review and meta-analysis
    • Rozen-Zvi B, Gafter-Gvili A, Paul M, Leibovici L, Shpilberg O, Gafter U. Intravenous versus oral iron supplementation for the treatment of anemia in CKD: systematic review and meta-analysis. Am J Kidney Dis. 2008; 52: 897-906.
    • (2008) Am J Kidney Dis , vol.52 , pp. 897-906
    • Rozen-Zvi, B.1    Gafter-Gvili, A.2    Paul, M.3    Leibovici, L.4    Shpilberg, O.5    Gafter, U.6
  • 30
    • 0029952883 scopus 로고    scopus 로고
    • A randomized controlled study of iron supplementation in patients treated with erythropoietin
    • Macdougall IC, Tucker B, Thompson J, Tomson CR, Baker LR, Raine AE. A randomized controlled study of iron supplementation in patients treated with erythropoietin. Kidney Int. 1996; 50: 1694-1699.
    • (1996) Kidney Int , vol.50 , pp. 1694-1699
    • Macdougall, I.C.1    Tucker, B.2    Thompson, J.3    Tomson, C.R.4    Baker, L.R.5    Raine, A.E.6
  • 31
    • 73049118236 scopus 로고    scopus 로고
    • Evolution of iv iron compounds over the last century
    • Macdougall IC. Evolution of iv iron compounds over the last century. J Ren Care. 2009; 35 (Suppl 2): 8-13.
    • (2009) J Ren Care , vol.35 , Issue.SUPPL. 2 , pp. 8-13
    • Macdougall, I.C.1
  • 32
    • 0003171680 scopus 로고    scopus 로고
    • Clinical practice guidelines for nutrition in chronic renal failure
    • K/DOQI, National Kidney Foundation
    • K/DOQI, National Kidney Foundation. Clinical practice guidelines for nutrition in chronic renal failure. Am J Kidney Dis. 2000; 35 (Suppl 2): S1-S140.
    • (2000) Am J Kidney Dis , vol.35 , Issue.SUPPL. 2
  • 34
    • 68049147210 scopus 로고    scopus 로고
    • Comparison of intravenous iron sucrose versus low-molecular-weight iron dextran in chronic kidney disease
    • Sinha S, Chiu DY, Peebles G, Kolakkat S, Lamerton E, Fenwick S, Kalra PA. Comparison of intravenous iron sucrose versus low-molecular-weight iron dextran in chronic kidney disease. J Ren Care. 2009; 35: 67-73.
    • (2009) J Ren Care , vol.35 , pp. 67-73
    • Sinha, S.1    Chiu, D.Y.2    Peebles, G.3    Kolakkat, S.4    Lamerton, E.5    Fenwick, S.6    Kalra, P.A.7
  • 35
    • 0036511339 scopus 로고    scopus 로고
    • The biological and economic value of oral organic iron in maintenance dialysis
    • Wish JB, Fourtner P, Ghaddar S, Moore GM. The biological and economic value of oral organic iron in maintenance dialysis. Nephrol News Issues. 2002; 16: 32-33, 37-39.
    • (2002) Nephrol News Issues , vol.16 , Issue.32-33 , pp. 37-39
    • Wish, J.B.1    Fourtner, P.2    Ghaddar, S.3    Moore, G.M.4
  • 36
    • 84861523138 scopus 로고    scopus 로고
    • Beneficial effects of maintenance intravenous iron saccharate in hemodialysis patients
    • Al-Mueilo SH. Beneficial effects of maintenance intravenous iron saccharate in hemodialysis patients. Saudi J Kidney Dis Transpl. 2005; 16: 146-153.
    • (2005) Saudi J Kidney Dis Transpl , vol.16 , pp. 146-153
    • Al-Mueilo, S.H.1
  • 37
    • 0029894558 scopus 로고    scopus 로고
    • Pharmacokinetics of iron(III)-hydroxide sucrose complex after a single intravenous dose in healthy volunteers
    • Danielson BG, Salmonson T, Derendorf H, Geisser P. Pharmacokinetics of iron(III)-hydroxide sucrose complex after a single intravenous dose in healthy volunteers. Arzneimittelforschung. 1996; 46: 615-621.
    • (1996) Arzneimittelforschung , vol.46 , pp. 615-621
    • Danielson, B.G.1    Salmonson, T.2    Derendorf, H.3    Geisser, P.4
  • 38
    • 77954886707 scopus 로고    scopus 로고
    • Plasma pharmacokinetics of two consecutive doses of ferumoxytol in healthy subjects
    • Pai AB, Nielsen JC, Kausz A, Miller P, Owen JS. Plasma pharmacokinetics of two consecutive doses of ferumoxytol in healthy subjects. Clin Pharmacol Ther. 2010; 88: 237-242.
    • (2010) Clin Pharmacol Ther , vol.88 , pp. 237-242
    • Pai, A.B.1    Nielsen, J.C.2    Kausz, A.3    Miller, P.4    Owen, J.S.5
  • 39
    • 79955586213 scopus 로고    scopus 로고
    • A randomized controlled trial comparing intravenous ferric carboxymaltose with oral iron for treatment of iron deficiency anaemia of non-dialysis-dependent chronic kidney disease patients
    • Qunibi WY, Martinez C, Smith M, Benjamin J, Mangione A, Roger SD. A randomized controlled trial comparing intravenous ferric carboxymaltose with oral iron for treatment of iron deficiency anaemia of non-dialysis-dependent chronic kidney disease patients. Nephrol Dial Transplant. 2010; 27: 1599-1607.
    • (2010) Nephrol Dial Transplant , vol.27 , pp. 1599-1607
    • Qunibi, W.Y.1    Martinez, C.2    Smith, M.3    Benjamin, J.4    Mangione, A.5    Roger, S.D.6
  • 40
    • 77349120060 scopus 로고    scopus 로고
    • Safety and tolerability of intravenous ferric carboxymaltose in patients with iron deficiency anemia
    • Bailie GR, Mason NA, Valaoras TG. Safety and tolerability of intravenous ferric carboxymaltose in patients with iron deficiency anemia. Hemodial Int. 2010; 14: 47-54.
    • (2010) Hemodial Int , vol.14 , pp. 47-54
    • Bailie, G.R.1    Mason, N.A.2    Valaoras, T.G.3
  • 41
    • 0032943940 scopus 로고    scopus 로고
    • Dialysate iron therapy: infusion of soluble ferric pyrophosphate via the dialysate during hemodialysis
    • Gupta A, Amin NB, Besarab A, Vogel SE, Divine GW, Yee J, Anandan JV. Dialysate iron therapy: infusion of soluble ferric pyrophosphate via the dialysate during hemodialysis. Kidney Int. 1999; 55: 1891-1898.
    • (1999) Kidney Int , vol.55 , pp. 1891-1898
    • Gupta, A.1    Amin, N.B.2    Besarab, A.3    Vogel, S.E.4    Divine, G.W.5    Yee, J.6    Anandan, J.V.7
  • 42
    • 33847791606 scopus 로고    scopus 로고
    • Should we limit the ferritin upper threshold to 500 ng/ml in CKD patients?
    • Dukkipati R, Kalantar-Zadeh K. Should we limit the ferritin upper threshold to 500 ng/ml in CKD patients? Nephrol News Issues. 2007; 21: 34-38.
    • (2007) Nephrol News Issues , vol.21 , pp. 34-38
    • Dukkipati, R.1    Kalantar-Zadeh, K.2
  • 43
    • 77749282884 scopus 로고    scopus 로고
    • Can the response to iron therapy be predicted in anemic nondialysis patients with chronic kidney disease?
    • Stancu S, Bârsan L, Stanciu A, Mircescu G. Can the response to iron therapy be predicted in anemic nondialysis patients with chronic kidney disease? Clin J Am Soc Nephrol. 2010; 5: 409-416.
    • (2010) Clin J Am Soc Nephrol , vol.5 , pp. 409-416
    • Stancu, S.1    Bârsan, L.2    Stanciu, A.3    Mircescu, G.4
  • 44
    • 77949559450 scopus 로고    scopus 로고
    • Bone marrow iron, iron indices, and the response to intravenous iron in patients with non-dialysis-dependent CKD
    • Stancu S, Stanciu A, Zugravu A, Bârsan L, Dumitru D, Lipan M, Mircescu G. Bone marrow iron, iron indices, and the response to intravenous iron in patients with non-dialysis-dependent CKD. Am J Kidney Dis. 2010; 55: 639-647.
    • (2010) Am J Kidney Dis , vol.55 , pp. 639-647
    • Stancu, S.1    Stanciu, A.2    Zugravu, A.3    Bârsan, L.4    Dumitru, D.5    Lipan, M.6    Mircescu, G.7
  • 45
    • 34047235103 scopus 로고    scopus 로고
    • In vivo imaging of hepcidin promoter stimulation by iron and inflammation
    • Flanagan JM, Truksa J, Peng H, Lee P, Beutler E. In vivo imaging of hepcidin promoter stimulation by iron and inflammation. Blood Cells Mol Dis. 2007; 38: 253-257.
    • (2007) Blood Cells Mol Dis , vol.38 , pp. 253-257
    • Flanagan, J.M.1    Truksa, J.2    Peng, H.3    Lee, P.4    Beutler, E.5
  • 46
    • 0033756150 scopus 로고    scopus 로고
    • Catalytically active iron and bacterial growth in serum of haemodialysis patients after i.v. iron-saccharate administration
    • Parkkinen J, von Bonsdorff L, Peltonen S, Grönhagen-Riska C, Rosenlöf K. Catalytically active iron and bacterial growth in serum of haemodialysis patients after i.v. iron-saccharate administration. Nephrol Dial Transplant. 2000; 15: 1827-1834.
    • (2000) Nephrol Dial Transplant , vol.15 , pp. 1827-1834
    • Parkkinen, J.1    von Bonsdorff, L.2    Peltonen, S.3    Grönhagen-Riska, C.4    Rosenlöf, K.5
  • 47
    • 75149167105 scopus 로고    scopus 로고
    • Ferumoxytol: a new intravenous iron preparation for the treatment of iron deficiency anemia in patients with chronic kidney disease
    • Schwenk MH. Ferumoxytol: a new intravenous iron preparation for the treatment of iron deficiency anemia in patients with chronic kidney disease. Pharmacotherapy. 2010; 30: 70-79.
    • (2010) Pharmacotherapy , vol.30 , pp. 70-79
    • Schwenk, M.H.1
  • 48
    • 70350688114 scopus 로고    scopus 로고
    • The role of labile iron in kidney disease and treatment with chelation
    • Shah SV, Rajapurkar MM. The role of labile iron in kidney disease and treatment with chelation. Hemoglobin. 2009; 33: 378-385.
    • (2009) Hemoglobin , vol.33 , pp. 378-385
    • Shah, S.V.1    Rajapurkar, M.M.2
  • 49
    • 79251523888 scopus 로고    scopus 로고
    • Proteinuria Induced by Parenteral Iron in Chronic Kidney Disease - A Comparative Randomized Controlled Trial
    • Agarwal R, Leehey DJ, Olsen SM, Dahl NV. Proteinuria Induced by Parenteral Iron in Chronic Kidney Disease - A Comparative Randomized Controlled Trial. Clin J Am Soc Nephrol. 2010; 6: 114-121.
    • (2010) Clin J Am Soc Nephrol , vol.6 , pp. 114-121
    • Agarwal, R.1    Leehey, D.J.2    Olsen, S.M.3    Dahl, N.V.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.