CCR7/CCL19 controls expression of EDG-1 in T cells

Journal of Biological Chemistry

Volumn 287, Issue 15, 2012, Pages 11656-11664

  Shannon, Laura A ^a   McBurney, Tiffany M ^a   Wells, Melissa A ^a,b   Roth, Megan E ^a   Calloway, Psachal A ^a   Bill, Charles A ^a   Islam, Shamima ^a   Vines, Charlotte M ^a  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^b MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BASAL LEVELS; CELLULAR EFFECTS; CHEMOKINE RECEPTORS; COGNATE LIGANDS; CONTROL MIGRATION; ENDOTHELIAL DIFFERENTIATION; EXTRACELLULAR SIGNAL-REGULATED KINASE; HUMAN T CELLS; IMMUNE FUNCTION; LYMPH NODE; SIGNALING EVENTS; SIGNALING PATHWAYS; T CELLS; T LYMPHOCYTES; UP-REGULATION;

BODY FLUIDS; CELL CULTURE; CELLS; GENES; PHOSPHORYLATION; SIGNALING; TISSUE; TRANSCRIPTION FACTORS;

LIGANDS;

CHEMOKINE RECEPTOR CCR7; KRUPPEL LIKE FACTOR 2; MACROPHAGE INFLAMMATORY PROTEIN 3BETA; MITOGEN ACTIVATED PROTEIN KINASE 7; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE RECEPTOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DENDRITIC CELL; HUMAN; HUMAN CELL; LYMPH NODE; LYMPHOCYTE MIGRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; UPREGULATION;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; CELL LINE; CHEMOKINE CCL19; CHEMOKINE CCL21; CHEMOTAXIS; DENDRITIC CELLS; GENE EXPRESSION; GENE EXPRESSION REGULATION; HUMANS; LYSOPHOSPHOLIPIDS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASE 7; PHOSPHORYLATION; RECEPTORS, CCR7; RECEPTORS, LYSOSPHINGOLIPID; SIGNAL TRANSDUCTION; SPHINGOSINE; T-LYMPHOCYTES;

MURINAE;

EID: 84859479189     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.310045     Document Type: Article

References (38)

1. Dailey, M. O., Gallatin, W. M., and Weissman, I. L. (1985) The in vivo behavior of T cell clones: altered migration due to loss of the lymphocyte surface homing receptor. J. Mol. Cell. Immunol. 2, 27-36 (Pubitemid 15112483)
2. Fan, L., Reilly, C. R., Luo, Y., Dorf, M. E., and Lo, D. (2000) Cutting edge: ectopic expression of the chemokine TCA4/SLC is sufficient to trigger lymphoid neogenesis. J. Immunol. 164, 3955-3959 (Pubitemid 30215047)
3. Gunn, M. D., Kyuwa, S., Tam, C., Kakiuchi, T., Matsuzawa, A., Williams, L. T., and Nakano, H. (1999) Mice lacking expression of secondary lymphoid organ chemokine have defects in lymphocyte homing and dendritic cell localization. J. Exp. Med. 189, 451-460 (Pubitemid 29187367)
4. Luther, S. A., Tang, H. L., Hyman, P. L., Farr, A. G., and Cyster, J. G. (2000) Coexpression of the chemokines ELC and SLC by T zone stromal cells and deletion of the ELC gene in the plt/plt mouse. Proc. Natl. Acad. Sci. U.S.A. 97, 12694-12699
5. Ngo, V. N., Korner, H., Gunn, M. D., Schmidt, K. N., Riminton, D. S., Cooper, M. D., Browning, J. L., Sedgwick, J. D., and Cyster, J. G. (1999) Lymphotoxin α/β and tumor necrosis factor are required for stromal cell expression of homing chemokines in B and T cell areas of the spleen. J. Exp. Med. 189, 403-412 (Pubitemid 29063261)
6. Campbell, J. J., Bowman, E. P., Murphy, K., Youngman, K. R., Siani, M. A., Thompson, D. A., Wu, L., Zlotnik, A., and Butcher, E. C. (1998) 6-C-kine (SLC), a lymphocyte adhesion-triggering chemokine expressed by high endothelium, is an agonist for the MIP-3β receptor CCR7. J. Cell Biol. 141, 1053-1059 (Pubitemid 28243971)
7. Byers, M. A., Calloway, P. A., Shannon, L., Cunningham, H. D., Smith, S., Li, F., Fassold, B. C., and Vines, C. M. (2008) Arrestin 3 mediates endocytosis of CCR7 following ligation of CCL19 but not CCL21. J. Immunol. 181, 4723-4732
8. Luther, S. A., Bidgol, A., Hargreaves, D. C., Schmidt, A., Xu, Y., Paniyadi, J., Matloubian, M., and Cyster, J. G. (2002) Differing activities of homeostatic chemokines CCL19, CCL21, and CXCL12 in lymphocyte and dendritic cell recruitment and lymphoid neogenesis. J. Immunol. 169, 424-433 (Pubitemid 34686164)
9. Otero, C., Groettrup, M., and Legler, D. F. (2006) Opposite fate of endocytosed CCR7 and its ligands: recycling versus degradation. J. Immunol. 177, 2314-2323 (Pubitemid 44200991)
10. Bardi, G., Lipp, M., Baggiolini, M., and Loetscher, P. (2001) The T cell chemokine receptor CCR7 is internalized on stimulation with ELC, but not with SLC. Eur. J. Immunol. 31, 3291-3297 (Pubitemid 33100521)
11. Nakano, H., Mori, S., Yonekawa, H., Nariuchi, H., Matsuzawa, A., and Kakiuchi, T. (1998) A novel mutant gene involved in T-lymphocyte-specific homing into peripheral lymphoid organs on mouse chromosome 4. Blood 91, 2886-2895 (Pubitemid 28227539)
12. Nakano, H., Tamura, T., Yoshimoto, T., Yagita, H., Miyasaka, M., Butcher, E. C., Nariuchi, H., Kakiuchi, T., and Matsuzawa, A. (1997) Genetic defect in T lymphocyte-specific homing into peripheral lymph nodes. Eur. J. Immunol. 27, 215-221 (Pubitemid 27046081)
13. Förster, R., Schubel, A., Breitfeld, D., Kremmer, E., Renner-Müller, I., Wolf, E., and Lipp, M. (1999) CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs. Cell 99, 23-33 (Pubitemid 29468627)
14. Link, A., Vogt, T. K., Favre, S., Britschgi, M. R., Acha-Orbea, H., Hinz, B., Cyster, J. G., and Luther, S. A. (2007) Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells. Nat. Immunol. 8, 1255-1265 (Pubitemid 350011765)
15. Pilkington, K. R., Clark-Lewis, I., and McColl, S. R. (2004) Inhibition of generation of cytotoxic T lymphocyte activity by a CCL19/macrophage inflammatory protein (MIP)-3β antagonist. J. Biol. Chem. 279, 40276-40282 (Pubitemid 39287611)
16. Matloubian, M., Lo, C. G., Cinamon, G., Lesneski, M. J., Xu, Y., Brinkmann, V., Allende, M. L., Proia, R. L., and Cyster, J. G. (2004) Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1. Nature 427, 355-360 (Pubitemid 38133663)
17. i-coupled receptors to promote T cell egress. Immunity 28, 122-133
18. Carlson, C. M., Endrizzi, B. T., Wu, J., Ding, X., Weinreich, M. A., Walsh, E. R., Wani, M. A., Lingrel, J. B., Hogquist, K. A., and Jameson, S. C. (2006) Kruppel-like factor 2 regulates thymocyte and T-cell migration. Nature 442, 299-302 (Pubitemid 44114904)
19. Ananieva, O., Macdonald, A., Wang, X., McCoy, C. E., McIlrath, J., Tournier, C., and Arthur, J. S. (2008) ERK5 regulation in naïve T-cell activation and survival. Eur. J. Immunol. 38, 2534-2547
20. Hennet, T., Hagen, F. K., Tabak, L. A., and Marth, J. D. (1995) T-cell-specific deletion of a polypeptide N-acetylgalactosaminyl-transferase gene by site-directed recombination. Proc. Natl. Acad. Sci. U.S.A. 92, 12070-12074
21. Lutz, M. B., Kukutsch, N., Ogilvie, A. L., Rössner, S., Koch, F., Romani, N., and Schuler, G. (1999) An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow. J. Immunol. Methods 223, 77-92 (Pubitemid 29096240)
22. Vines, C. M., Potter, J. W., Xu, Y., Geahlen, R. L., Costello, P. S., Tybulewicz, V. L., Lowell, C. A., Chang, P. W., Gresham, H. D., and Willman, C. L. (2001) Inhibition of β2 integrin receptor and Syk kinase signaling in monocytes by the Src family kinase Fgr. Immunity 15, 507-519 (Pubitemid 33016437)
23. Stoll, S., Delon, J., Brotz, T. M., and Germain, R. N. (2002) Dynamic imaging of T cell-dendritic cell interactions in lymph nodes. Science 296, 1873-1876 (Pubitemid 34596274)
24. Mempel, T. R., Henrickson, S. E., and Von Andrian, U. H. (2004) T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases. Nature 427, 154-159 (Pubitemid 38094955)
25. Sohn, S. J., Li, D., Lee, L. K., and Winoto, A. (2005) Transcriptional regulation of tissue-specific genes by the ERK5 mitogen-activated protein kinase. Mol. Cell. Biol. 25, 8553-8566 (Pubitemid 41369176)
26. Rovida, E., Spinelli, E., Sdelci, S., Barbetti, V., Morandi, A., Giuntoli, S., and Dello Sbarba, P. (2008) ERK5/BMK1 is indispensable for optimal colony-stimulating factor 1 (CSF-1)-induced proliferation in macrophages in a Src-dependent fashion. J. Immunol. 180, 4166-4172
27. Nishimoto, S., and Nishida, E. (2006) MAPK signaling: ERK5 versus ERK1/2. EMBO Rep. 7, 782-786 (Pubitemid 44275395)
28. Kohout, T. A., Nicholas, S. L., Perry, S. J., Reinhart, G., Junger, S., and Struthers, R. S. (2004) Differential desensitization, receptor phosphorylation, β-arrestin recruitment, and ERK1/2 activation by the two endogenous ligands for the CC chemokine receptor 7. J. Biol. Chem. 279, 23214-23222 (Pubitemid 38685628)
29. Buschbeck, M., and Ullrich, A. (2005) The unique C-terminal tail of the mitogen-activated protein kinase ERK5 regulates its activation and nuclear shuttling. J. Biol. Chem. 280, 2659-2667 (Pubitemid 40189370)
30. Schober, S. L., Kuo, C. T., Schluns, K. S., Lefrancois, L., Leiden, J. M., and Jameson, S. C. (1999) Expression of the transcription factor lung Krüppel-like factor is regulated by cytokines and correlates with survival of memory T cells in vitro and in vivo. J. Immunol. 163, 3662-3667 (Pubitemid 29450887)
31. Otero, C., Eisele, P. S., Schaeuble, K., Groettrup, M., and Legler, D. F. (2008) Distinct motifs in the chemokine receptor CCR7 regulate signal transduction, receptor trafficking, and chemotaxis. J. Cell Sci. 121, 2759-2767
32. Arcand, J., Robitaille, G., Koenig, M., Senecal, J. L., and Raymond, Y. (2012) Arthritis Rheum. 64, 826-834
33. Cabioglu, N., Yazici, M. S., Arun, B., Broglio, K. R., Hortobagyi, G. N., Price, J. E., and Sahin, A. (2005) CCR7 and CXCR4 as novel biomarkers predicting axillary lymph node metastasis in T1 breast cancer. Clin. Cancer Res. 11, 5686-5693 (Pubitemid 41170291)
34. Kuo, C. T., Veselits, M. L., and Leiden, J. M. (1997) LKLF: A transcriptional regulator of single-positive T cell quiescence and survival. Science 277, 1986-1990 (Pubitemid 27449139)
35. Sohn, S. J., Lewis, G. M., and Winoto, A. (2008) Non-redundant function of the MEK5-ERK5 pathway in thymocyte apoptosis. EMBO J. 27, 1896-1906 (Pubitemid 351960211)
36. Greer, E. L., and Brunet, A. (2005) FOXO transcription factors at the interface between longevity and tumor suppression. Oncogene 24, 7410-7425 (Pubitemid 41637981)
37. Kerdiles, Y. M., Beisner, D. R., Tinoco, R., Dejean, A. S., Castrillon, D. H., DePinho, R. A., and Hedrick, S. M. (2009) Foxo1 links homing and survival of naive T cells by regulating L-selectin, CCR7 and interleukin 7 receptor. Nat. Immunol. 10, 176-184
38. Huang, Y. H., Li, D., Winoto, A., and Robey, E. A. (2004) Distinct transcriptional programs in thymocytes responding to T cell receptor, Notch, and positive selection signals. Proc. Natl. Acad. Sci. U.S.A. 101, 4936-4941 (Pubitemid 38469181)