Correlation of CYP1A1, GSTP1 and GSTM1 gene polymorphisms and lung cancer risk among smokers

Oncology Letters

Volumn 3, Issue 6, 2012, Pages 1301-1306

  Pliarchopoulou, Kyriaki ^a   Voutsinas, Gerasimos ^b   Papaxoinis, George ^a   Florou, Katherine ^a   Skondra, Maria ^a   Kostaki, Konstantina ^a   Roussou, Paraskevi ^c   Syrigos, Konstantinos ^c   Pectasides, Dimitrios ^a  

^a HIPPOKRATION HOSPITAL   (Greece)

^b Demokritos Biology Institute   (Greece)

^c SOTIRIA GENERAL HOSPITAL   (Greece)

Author keywords

Carcinogen metabolism; Lung cancer; Polymorphisms; Smoking

Indexed keywords

CYTOCHROME P450 1A1; GLUTATHIONE TRANSFERASE M1; GLUTATHIONE TRANSFERASE P1; LEUCINE; VALINE;

ADVANCED CANCER; AGED; ARTICLE; CANCER PATIENT; CANCER RISK; CANCER SCREENING; CANCER SURVIVAL; CANCER SUSCEPTIBILITY; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA POLYMORPHISM; FEMALE; FOLLOW UP; GENE DELETION; GENE FREQUENCY; GENOTYPE; HETEROZYGOSITY; HISTOLOGY; HOMOZYGOSITY; HUMAN; LUNG CANCER; LUNG NON SMALL CELL CANCER; MAJOR CLINICAL STUDY; MALE; SMOKING;

EID: 84859478185     PISSN: 17921074     EISSN: 17921082     Source Type: Journal    
DOI: 10.3892/ol.2012.665     Document Type: Article

References (29)

1. Parkin DM, Bray F, Ferlay J and Pisani P: Global cancer statistics, 2002. CA Cancer J Clin 55: 74-108, 2005.
2. Tamura T: New state of the art in small-cell lung cancer. Oncology (Williston Park) 15: 8-10, 2001.
3. Khuder SA and Mutgi AB: Effect of smoking cessation on major histologic types of lung cancer. Chest 120: 1577-1583, 2001.
4. Kiyohara C, Shirakawa T and Hopkin JM: Genetic polymorphism of enzymes involved in xenobiotic metabolism and the risk of lung cancer. Env Health Prev Med 7: 47-59, 2002.
5. Kawajiri K, Nakachi K, Imai K, Watanabe J and Hayashi S: The CYP1A1 gene and cancer susceptibility. Crit Rev Oncol Hematol 14: 77-87, 1993.
6. Benhamou S, Lee WJ, Alexandrie AK, Boffetta P, Bouchardy C, Butkiewicz D, Brockmöller J, Clapper ML, Daly A, Dolzan V,et al: Meta- and pooled analyses of the effects of glutathione S-transferase M1 polymorphisms and smoking in lung cancer risk. Carcinogenesis 23: 1343-1350, 2002.
7. Ye Z, Song H, Higgins JP, Pharoah P and Danesh J: Five glutathione S-transferase gene variants in 23452 cases of lung cancer and 30397 controls: meta-analysis of 130 studies. PLoS Med 3: 91, 2003.
8. Denissenko M, Pao A, Tang MS and Pfeifer GP: Preferential formation of benzo(a)pyrene adducts at lung cancer mutational hotspots in p53. Science 274: 430-432, 1996.
9. Wiencke J, Varkonyi A, Semey K, et al: Detection of benzene-related DNA adducts in human tissues and evidence of co-activation with polyaromatic hydrocarbons. Proc Am Assoc Cancer Res 36: 135, 1995.
10. Kriek E, Van Shooten FJ, Hillebrand MJX, Van Leeuwen FE, Den Engelse L, De Looff AJ and Dijkmans AP: DNA adducts as a measure of lung cancer risk in human exposed to polycyclic aromatic hydrocarbons. Env Health Perspect 99: 71-75, 1993.
11. Bouchardy C, Benhamou S, Jourenkova N, Dayer P and Hirvonen A: Metabolic genetic polymorphisms and susceptibility to lung cancer. Lung Cancer 32: 109-112, 2001.
12. Raunio H, Husgafvel-Pursianinen K, Anttila S, Hietanen E, Hirvonen A and Pelkonen O: Diagnosis of polymorphisms in carcinogen-activating and inactivating enzymes and cancer susceptibility-a review. Gene 159: 113-121, 1995.
13. Perera FP, Mooney LA, Stampfer M, Phillips DH, Bell DA, Rundle A, Cho S, Tsai WY, Ma J, Blackwood A and Tang D: Associations between carcinogen-DNA damage, glutathione S-transferase genotypes and risk of lung cancer in the prospective Physicians' Health Cohort Study. Carcinogenesis 23: 1641-1646, 2002.
14. Kumar M, Agarwal SK and Goel SK: Lung cancer risk in north Indian population: role of genetic polymorphisms and smoking. Mol Cell Biochem 322: 73-79, 2009.
15. San Jose C, Cabanillas A, Benitez J, Carrillo JA, Jimenez M and Gervasini G: CYP1A1 gene polymorphisms increase lung cancer risk in a high-incidence region of Spain: a case-control study. BMC Cancer 10: 463, 2010.
16. Sampaio AC, Morari EC, Bufalo NE, Leite JL, Lima CS and Ward LS: Lack of influence of glutathione S-transferase genotype profile on cancer susceptibility in smokers and non-smokers. Med Sci Monit 15: 10-15, 2009.
17. Bartsch H, Nair U, Risch A, Rojas M, Wikman H and Alexandrov K: Genetic polymorphism of CYP genes, alone or in combination, as a risk modifier of tobacco-related cancers. Cancer Epidem Biom Prev 9: 3-28, 2000.
18. Hung RJ, Boffetta P, Brockmoller J, Butkiewicz D, Cascorbi I,Clapper ML, Garte S, Haugen A, Hirvonen A, Anttila S, et al: CYP1A1 and GSTM1 genetic polymorphisms and lung cancer risk in Caucasian non-smokers: a pooled analysis. Carcinogenesis 24: 875-882, 2003.
19. Cote ML, Chen W, Smith DW, Benhamou S, Bouchardy C, Butkiewicz D, Fong KM, Gené M, Hirvonen A, Kiyohara C, et al: Meta- and pooled analysis of GSTP1 polymorphism and lung cancer: a HuGE-GSEC review. Am J Epidem 169: 802-814, 2009.
20. Carlsten C, Saggo GS, Frodsham AJ, Burke W and Higgins JP: Glutathione S-transferase M1 (GSTM1) polymorphisms and lung cancer: a literature-based systematic HuGE review and meta-analysis. Am J Epidem 167: 759-774, 2008.
21. Butkiewicz D, Grzybowska E, Phillips DH, Hemminki K and Chorazy M: Polymorphisms of the GSTP1 and GSTM1 genes and PAH-DNA adducts in human mononuclear white blood cells. Environ Mol Mutagen 35: 99-105, 2000.
22. Chen Z, Li Z, Niu X, Yu Y, Lu S and Chen Z: The effect of CYP1A1 polymorphism on the risk of lung cancer: a global meta-analysis based on 71 case-control studies. Mutagenesis 26: 437-446, 2011.
23. Dialyna IA, Miyakis S, Georgatou N and Spandidos DA: Genetic polymorphisms of CYP1A1, GSTM1 and GSTT1 and lung cancer risk. Oncol Rep 10: 1829-1835, 2003.
24. Risch A, Wikman H, Thiel S, Schmezer P, Edler L, Drings P, Dienemann H, Kayser K, Schulz V, Spiegelhalder B and Bartsch H: Glutathione S-transferase M1, M3, T1 and P1 polymorphisms and susceptibility to non-small cell lung cancer subtypes and hamartomas. Pharmacogenetics 11: 757-764, 2001.
25. Lu C, Spitz MR, Zhao H, Dong Q, Truong M, Chang JY, Blumenschein GR Jr, Hong WK and Wu X: Association between glutathione S-transferase pi polymorphisms and survival in patients with advanced non-small cell lung carcinoma. Cancer 106: 441-447, 2006.
26. Sreeja L, Syamala V, Hariharan S, Syamala VS, Raveendran PB, Sivanandan CD, Madhavan J and Ankathil R: Glutathione S-transferase M1, T1 and P1 polymorphisms: susceptibility and outcome in lung cancer patients. J Exp Ther Oncol 7: 73-85, 2008.
27. Sweeney C, Nazar-Stewart V, Stapleton PL, Eaton DL and Vaughan TL: Glutathione S-transferase M1, T1 and P1 polymorphisms and survival among lung cancer patients. Cancer Epid Biom Prev 12: 527-533, 2003.
28. Goto I, Yoneda S, Yamamoto M and Kawajiri K: Prognostic significance of germ-line polymorphisms of the CYP1A1 and glutathione S-transferase genes in patients with non-small cell lung cancer. Cancer Res 56: 3725-3730, 1996.
29. Ada AO, Kunak CS, Hancer F, Soydas E, Alpar S, Gulhan M and Iscan M: CYP and GST polymorphisms and survival in advanced non-small cell lung cancer patients. Neoplasma 57: 512-521, 2010.