CYP1A1 and GSTM1 genetic polymorphisms and lung cancer risk in Caucasian non-smokers: A pooled analysis

Carcinogenesis

Volumn 24, Issue 5, 2003, Pages 875-882

  Hung, Rayjean J ^a,b   Boffetta, Paolo ^a   Brockmöller, Jürgen ^c   Butkiewicz, Dorota ^d   Cascorbi, Ingolf ^e   Clapper, Margie L ^f   Garte, Seymour ^g   Haugen, Aage ^h   Hirvonen, Ari ⁱ   Anttila, Sisko ⁱ   Kalina, Ivan ^j   Le Marchand, Loïc ^k   London, Stephanie J ^l   Rannug, Agneta ^m   Romkes, Marjorie ⁿ   Salagovic, Jan ^j   Schoket, Bernadette ^o   Gaspari, Laura ^p   Taioli, Emanuela ^p  

^a INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF GÖTTINGEN   (Germany)

^d INSTITUTE OF ONCOLOGY   (Poland)

^e UNIVERSITY OF GREIFSWALD   (Germany)

^f FOX CHASE CANCER CENTER   (United States)

^g Genetics Research Institute   (Italy)

^h NATIONAL INSTITUTE OF OCCUPATIONAL HEALTH   (Norway)

ⁱ FINNISH INSTITUTE OF OCCUPATIONAL HEALTH   (Finland)

^j P J AFÁRIK UNIVERSITY   (Slovakia)

^k UNIVERSITY OF HAWAII CANCER CENTER   (United States)

^l NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^m KAROLINSKA INSTITUTE   (Sweden)

ⁿ UNIVERSITY OF PITTSBURGH   (United States)

^o NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH   (Hungary)

^p UNIVERSITY OF MILAN   (Italy)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOGEN; CYTOCHROME P450 1A1; GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE M1; UNCLASSIFIED DRUG;

ALLELE; CANCER RISK; CASE CONTROL STUDY; CAUCASIAN; CIGARETTE SMOKING; CONFIDENCE INTERVAL; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; FEMALE; GENETIC ANALYSIS; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HUMAN; LUNG CANCER; LUNG CARCINOGENESIS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RANDOMIZATION; REVIEW; RISK ASSESSMENT; STATISTICAL ANALYSIS; URBAN RURAL DIFFERENCE; WILD TYPE;

CASE-CONTROL STUDIES; CYTOCHROME P-450 CYP1A1; EUROPE; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENE FREQUENCY; GENOTYPE; GLUTATHIONE TRANSFERASE; HUMANS; LUNG NEOPLASMS; ODDS RATIO; POLYMORPHISM, GENETIC; RISK FACTORS; SMOKING; UNITED STATES;

EID: 12444252552     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/bgg026     Document Type: Review

References (60)

1. Ferlay,J., Bray,F., Pisani,P. and Parkin,D.M. (2001) GLOBOCAN 2000: Cancer Incidence, Mortality and Prevalence Worldwide (1.0), CancerBase no. 5. IARC, Lyon, France.
2. Parkin,D.M., Pisani,P. and Ferlay,J. (1999) Global cancer statistics. CA Cancer J. Clin., 49, 33-64.
3. Blot,W.J. and Fraumeni,J.F. (1996) Cancers of the lung and pleura. In Schottenfeld,D., Searle,J.G. and Fraumeni,J.F. (eds) Cancer Epidemiology and Prevention. Oxford University Press, New York, NY, pp. 637-665.
4. Baron,J.A. and Rohan,T.E. (1996) Tobacco. In Schottenfeld,D., Searle,J.G. and Fraumeni,J.F. (eds) Cancer Epidemiology and Prevention. Oxford University Press, New York, NY, pp. 269-288.
5. International Agency of Research on Cancer (1986) IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans. Tobacco Smoking. IARC, Lyon, France.
6. Fontham,E.T. (1990) Protective dietary factors and lung cancer. Int. J. Epidemiol., 19(suppl. 1), S32-S42.
7. Lagarde,F., Axelsson,G., Damber,L., Mellander,H., Nyberg,F. and Pershagen,G. (2001) Residential radon and lung cancer among never-smokers in Sweden. Epidemiology, 12, 396-404.
8. Brownson,R.C., Alavanja,M.C. and Chang,J.C. (1993) Occupational risk factors for lung cancer among nonsmoking women: a case-control study in Missouri (United States). Cancer Causes Control, 4, 449-454.
9. Brownson,R.C., Alavanja,M.C., Caporaso,N., Simoes,E.J. and Chang J.C. (1998) Epidemiology and prevention of lung cancer in nonsmokers. Epidemiol. Rev., 20, 218-236.
10. Strong,L.C. and Amos,C.I. (1996) Inherited susceptibility. In Schottenfeld,D., Searle,J.G. and Fraumeni,J.F. (eds) Cancer Epidemiology and Prevention. Oxford University Press, New York, NY, pp. 559-582.
11. Vineis,P., Malats,N., Lang,M., d'Errico,A., Caporaso,N., Cuzick,J. and Boffetta, P. (1999) Metabolic Polymorphisms and Susceptibility to Cancer, IARC Scientific Publications no. 148. IARC, Lyon, France.
12. Shields,P.G. (1998) Genetic susceptibility to tobacco related lung cancer. In Mendelsohn,M.L., Mohr,L.C. and Peeters,J.P. (eds) Biomarkers: Medical and Workplace Applications. National Academy of Sciences, Washington, DC, pp. 241-254.
13. Taioli,E. (1999) International collaborative study on genetic susceptibility to environmental carcinogens. Cancer Epidemiol. Biomarkers Prev., 8, 727-728.
14. Vineis,P., Bartsch,H., Caporaso,N. et al. (1994) Genetically based N-acetyltransferase metabolic polymorphism and low-level environmental exposure to carcinogens. Nature, 369, 154-156.
15. Vineis,P. and Martone,J. (1995) Genetic-environmental interactions and low-level exposure to carcinogens. Epidemiology, 6, 455-457.
16. Kawajiri,K. (1999) CYP1A1. In Vineis,P., Malats,N., Lang,M., d'Errico,A., Caporaso,N., Cuzick,J. and Boffetta,P. (eds) Metabolic Polymorphisms and Susceptibility to Cancer, IARC Scientific Publications no. 148. IARC, Lyon, France, pp. 159-172.
17. Cascorbi,I., Brockmoller,J. and Roots,I. (1996) A C4887 A polymorphism in exon 7 of human CYP1A1: population frequency, mutation linkages and impact on lung cancer susceptibility. Cancer Res., 56, 4965-4969.
18. Ingelman-Sundberg,M., Oscarson,M., Daly,A.K., Garte,S. and Nebert,D.W. (2001) Human cytochrome P-450 (CYP) genes: a web page for the nomenclature of alleles. Cancer Epidemiol. Biomarkers Prev., 10, 1307-1308.
19. Garte,S., Boffetta,P., Caporaso,N. and Vineis,P. (2001) Metabolic gene allele nomenclature. Cancer Epidemiol. Biomarkers Prev., 10, 1305-1306.
20. Bartsch,H., Nair,U., Risch,A., Rojas,M., Wikman,H. and Alexandrov,K. (2000) Genetic polymorphism of CYP genes, alone or in combination, as a risk modifier of tobacco-related cancers. Cancer Epidemiol. Biomarkers Prev., 9, 3-28.
21. Kawajiri,K., Nakachi,K., Imai,K., Watanabe,J. and Hayashi,S. (1993) The CYP1A1 gene and cancer susceptibility. Crit. Rev. Oncol. Hematol., 14, 77-87.
22. Kawajiri,K., Nakachi,K., Imai,K., Yoshii,A., Shinoda,N. and Watanabe,J. (1990) Identification of genetically high risk individuals to lung cancer by DNA polymorphisms of the cytochrome P4501A1 gene. FEBS Lett., 263, 131-133.
23. Houlston,R.S. (2000) CYP1A1 polymorphisms and lung cancer risk: a meta-analysis. Pharmacogenetics, 10, 105-114.
24. Strange,R.C. and Fryer,A.A. (1999) The glutathione S-transferases: influence of polymorphism on cancer susceptibility. In Vineis,P., Malats,N., Lang,M., d'Errico,A., Caporaso,N., Cuzick,J. and Boffetta,P. (eds) Metabolic Polymorphisms and Susceptibility to Cancer, IARC Scientific Publications no. 148. IARC, Lyon, France, pp. 231-249.
25. Eaton,D.L. and Bammler,T.K. (1999) Concise review of the glutathione S-transferases and their significance to toxicology. Toxicol. Sci., 49, 156-164.
26. d'Errico,A., Malats,N., Vineis,P. and Boffetta,P. (1999) Review of studies of selected metabolic polymorphisms and cancer. In Vineis,P., Malats,N., Lang,M., d'Errico,A., Caporaso,N., Cuzick,J. and Boffetta,P. (eds) Metabolic Polymorphisms and Susceptibility to Cancer, IARC Scientific Publications no. 148. IARC, Lyon, France, pp. 323-393.
27. Benhamou,S., Lee,W.J., Alexandrie,A.K. et al. (2002) Meta- and pooled analyses of the effects of glutathione S-transferase M1 polymorphisms and smoking on lung cancer risk. Carcinogenesis, 23, 1343-1350.
28. Malats,N., Camus-Radon,A.M., Nyberg,F. et al. (2000) Lung cancer risk in nonsmokers and GSTM1 and GSTT1 genetic polymorphism. Cancer Epidemiol. Biomarkers Prev., 9, 827-833.
29. Brockmoller,J., Kerb,R., Drakoulis,N., Nitz,M. and Roots,I. (1993) Genotype and phenotype of glutathione S-transferase class mu isoenzymes mu and psi in lung cancer patients and controls. Cancer Res., 53, 1004-1011.
30. Salagovic,J., Kalina,I., Stubna,J., Habalova,V., Hrivnak,M., Valansky,L., Kohut, A. and Biros, E. (1998) Genetic polymorphism of glutathione S-transferases M1 and T1 as a risk factor in lung and bladder cancers. Neoplasma, 45, 312-317.
31. DerSimonian,R. and Laird, N. (1986) Meta-analysis in clinical trials. Control Clin. Trials, 7, 177-188.
32. Egger,M., Davey,S.G., Schneider,M. and Minder,C. (1997) Bias in meta-analysis detected by a simple, graphical test. Br. Med. J., 315, 629-634.
33. Wacholder,S., Rothman,N. and Caporaso,N. (2000) Population stratification in epidemiologic studies of common genetic variants and cancer: quantification of bias. J. Natl Cancer Inst., 92, 1151-1158.
34. Nyberg,F., Agudo,A., Boffetta,P., Fortes,C., Gonzalez,C.A. and Pershagen,G. (1998) A European validation study of smoking and environmental tobacco smoke exposure in nonsmoking lung cancer cases and controls. Cancer Causes Control, 9, 173-182.
35. Cosma,G., Crofts,F., Taioli,E., Toniolo,P. and Garte,S. (1993) Relationship between genotype and function of the human CYP1A1 gene. J. Toxicol. Environ. Health, 40, 309-316.
36. Crofts,F., Taioli,E., Trachman,J., Cosma,G.N., Currie,D., Toniolo,P. and Garte,S.J. (1994) Functional significance of different human CYP1A1 genotypes. Carcinogenesis, 15, 2961-2963.
37. Kiyohara,C., Hirohata,T. and Inutsuka,S. (1996) The relationship between aryl hydrocarbon hydroxylase and polymorphisms of the CYP1A1 gene. Jpn J. Cancer Res., 87, 18-24.
38. Landi,M.T., Bertazzi,P.A., Shields,P.G., Clark,G., Lucier,G.W., Garte,S.J., Cosma,G. and Caporaso,N.E. (1994) Association between CYP1A1 genotype, mRNA expression and enzymatic activity in humans. Pharmacogenetics, 4, 242-246.
39. Zhang,Z.Y., Fasco,M.J., Huang,L., Guengerich,F.P. and Kaminsky, L.S. (1996) Characterization of purified human recombinant cytochrome P4501A1-Ile462 and - Va1462: assessment of a role for the rare allele in carcinogenesis. Cancer Res., 56, 3926-3933.
40. Persson,I., Johansson,I. and Ingelman-Sundberg,M. (1997) In vitro kinetics of two human CYP1A1 variant enzymes suggested to be associated with interindividual differences in cancer susceptibility. Biochem. Biophys. Res. Commun., 231, 227-230.
41. Schwarz,D., Kisselev,P., Cascorbi,J., Schunck,W.H. and Roots,I. (2001) Differential metabolism of benzo[a]pyrene and benzo[a]pyrene-7,8-dihydrodiol by human CYP1A1 variants. Carcinogenesis, 22, 453-459.
42. Chen,S., Xue,K., Xu,L., Ma,G. and Wu,J. (2001) Polymorphisms of the CYP1A1 and GSTM1 genes in relation to individual susceptibility to lung carcinoma in Chinese population. Mutat. Res., 458, 41-47.
43. Kihara,M., Kihara,M. and Noda,K. (1995) Risk of smoking for squamous and small cell carcinomas of the lung modulated by combinations of CYP1A1 and GSTM1 gene polymorphisms in a Japanese population. Carcinogenesis, 16, 2331-2336.
44. Stucker,I., Jacquet,M., de Waziers,I., Cenee,S., Beaune,P., Kremers,P. and Hemon, D. (2000) Relation between inducibility of CYP1A1, GSTM1 and lung cancer in a French population. Pharmacogenetics, 10, 617-627.
45. Schoket,B., Phillips,D.H., Kostic,S. and Vincze,I. (1998) Smoking-associated bulky DNA adducts in bronchial tissue related to CYP1A1 MspI and GSTM1 genotypes in lung patients. Carcinogenesis, 19, 841-846.
46. Anttila,S., Hirvonen,A., Husgafvel-Pursiainen,K., Karjalainen,A., Nurminen,T. and Vainio,H. (1994) Combined effect of CYP1A1 inducibility and GSTM1 polymorphism on histological type of lung cancer. Carcinogenesis, 15, 1133-1135.
47. Nielsen,P.S., Okkels,H., Sigsgaard,T., Kyrtopoulos,S. and Autrup,H. (1996) Exposure to urban and rural air pollution: DNA and protein adducts and effect of glutathione-S-transferase genotype on adduct levels. Int. Arch. Occup. Environ. Health, 68, 170-176.
48. Tefre,T., Ryberg,D., Haugen,A., Nebert,D.W., Skaug,V., Brogger,A. and Borresen,A.L. (1991) Human CYP1A1 (cytochrome P(1)450) gene: lack of association between the Msp I restriction fragment length polymorphism and incidence of lung cancer in a Norwegian population. Pharmacogenetics, 1, 20-25.
49. Ryberg,D., Skaug,V., Hewer,A., Phillips,D.H., Harries,L.W., Wolf,C.R., Ogreid,D., Ulvik,A., Vu,P. and Haugen,A. (1997) Genotypes of glutathione transferase M1 and P1 and their significance for lung DNA adduct levels and cancer risk. Carcinogenesis, 18, 1285-1289.
50. Hirvonen,A., Husgafvel-Pursiainen,K., Karjalainen,A., Anttila,S. and Vainio,H. (1992) Point-mutational MspI and Ile-Val polymorphisms closely linked in the CYP1A1 gene: lack of association with susceptibility to lung cancer in a Finnish study population. Cancer Epidemiol. Biomarkers Prev., 1, 485-489.
51. Saarikoski,S.T., Voho,A., Reinikainen,M., Anttila,S., Karjalainen,A., Malaveille,C., Vainio,H., Husgafvel-Pursiainen,K. and Hirvonen,A. (1998) Combined effect of polymorphic GST genes on individual susceptibility to lung cancer. Int. J. Cancer, 77, 516-521.
52. Roots,I., Brockmoller,J., Drakoulis,N. and Loddenkemper,R. (1992) Mutant genes of cytochrome P-450IID6, glutathione S-transferase class Mu and arylamine N-acetyltransferase in lung cancer patients. Clin. Invest., 70, 307-319.
53. Alexandrie,A.K., Sundberg,M.I., Seidegard,J., Tornling,G. and Rannug,A. (1994) Genetic susceptibility to lung cancer with special emphasis on CYP1A1 and GSTM1: a study on host factors in relation to age at onset, gender and histological cancer types. Carcinogenesis, 15, 1785-1790.
54. London,S.J., Daly,A.K., Cooper,J., Carpenter,C.L., Navidi,W.C., Ding,L. and Idle,J.R. (1996) Lung cancer risk in relation to the CYP2E1 Rsa I genetic polymorphism among African-Americans and Caucasians in Los Angeles County. Pharmacogenetics, 6, 151-158.
55. Leathart,J.B., London,S.J., Steward,A., Adams,J.D., Idle,J.R. and Daly,A.K. (1998) CYP2D6 phenotype-genotype relationships in African-Americans and Caucasians in Los Angeles. Pharmacogenetics, 8, 529-541.
56. Le Marchand,L., Sivaraman,L., Pierce,L., Seifried,A., Lum,A., Wilkens,L.R. and Lau,A.F. (1998) Associations of CYP1A1, GSTM1 and CYP2E1 polymorphisms with lung cancer suggest cell type specificities to tobacco carcinogens. Cancer Res., 58, 4858-4863.
57. Taioli,E., Ford,J., Trachman,J., Li,Y., Demopoulos,R. and Garte,S. (1998) Lung cancer risk and CYP1A1 genotype in African Americans. Carcinogenesis, 19, 813-817.
58. Ford,J.G., Li,Y., O'Sullivan,M.M., Demopoulos,R., Garte,S., Taioli,E. and Brandt-Rauf,P.W. (2000) Glutathione S-transferase M1 polymorphism and lung cancer risk in African-Americans. Carcinogenesis, 21, 1971 1975.
59. Butkiewicz,D., Cole,K.J., Phillips,D.H., Harris,C.C. and Chorazy,M. (1999) GSTM1, GSTP1, CYP1A1 and CYP2D6 polymorphisms in lung cancer patients from an environmentally polluted region of Poland: correlation with lung DNA adduct levels. Eur. J. Cancer Prev., 8, 315-323.
60. Dresler,C.M., Fratelli,C., Babb,J., Everley,L., Evans,A.A. and Clapper,M.L. (2000) Gender differences in genetic susceptibility for lung cancer. Lung Cancer, 30, 153-160.