Battle of the sexes: Conflict over dosage-sensitive genes and the origin of X chromosome inactivation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 14, 2012, Pages 5144-5145

  Wright, Alison E ^a,b   Mank, Judith E ^b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GENE DOSAGE; GENE EXPRESSION; GENE LOCUS; GENE OVEREXPRESSION; GENE SILENCING; GENETIC TRANSCRIPTION; NONHUMAN; NOTE; PRIORITY JOURNAL; SEX CHROMOSOME; SEX DIFFERENCE; TRANSCRIPTION REGULATION; X CHROMOSOME; X CHROMOSOME INACTIVATION;

ANIMALS; DOSAGE COMPENSATION, GENETIC; FEMALE; HUMANS; MALE; X CHROMOSOME INACTIVATION;

EID: 84859476448     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1202905109     Document Type: Note

References (17)

1. Pessia E, Makino T, Bailly-Bechet M, McLysaght A, Marais GAB (2012) Mammalian X chromosome inactivation evolved as a dosage-compensation mechanism for dosage-sensitive genes on the X chromosome. Proc Natl Acad Sci USA 109:5346-5351.
2. Papp B, Pál C, Hurst LD (2003) Dosage sensitivity and the evolution of gene families in yeast. Nature 424:194-197. (Pubitemid 36858686)
3. Hughes JF, et al. (2012) Strict evolutionary conservation followed rapid gene loss on human and rhesus Y chromosomes. Nature 483:82-86.
4. Ohno S (1967) Sex Chromosomes and Sex Linked Genes (Springer, Berlin).
5. Deakin JE, Hore TA, Koina E, Marshall Graves JA (2008) The status of dosage compensation in the multiple X chromosomes of the platypus. PLoS Genet 4:e1000140.
6. Itoh Y, et al. (2007) Dosage compensation is less effective in birds than in mammals. J Biol 6:2.
7. Mank JE (2009) The W, X, Y and Z of sex-chromosome dosage compensation. Trends Genet 25:226-233.
8. Vicoso B, Bachtrog D (2011) Lack of global dosage compensation in Schistosoma mansoni, a female-heterogametic parasite. Genome Biol Evol 3:230-235.
9. Deng XX, et al. (2011) Evidence for compensatory upregulation of expressed X-linked genes in mammals, Caenorhabditis elegans and Drosophila melanogaster. Nat Genet 43:1179-1185.
10. Kharchenko PV, Xi RB, Park PJ (2011) Evidence for dosage compensation between the X chromosome and autosomes in mammals. Nat Genet 43:1167-1169.
11. Xiong YY, et al. (2010) RNA sequencing shows no dosage compensation of the active X-chromosome. Nat Genet 42:1043-1047.
12. Makino T, McLysaght A (2010) Ohnologs in the human genome are dosage balanced and frequently associated with disease. Proc Natl Acad Sci USA 107:9270-9274.
13. Mank JE, Hosken DJ, Wedell N (2011) Some inconvenient truths about sex chromosome dosage compensation and the potential role of sexual conflict. Evolution 65:2133-2144.
14. Zhang LQ, Li WH (2004) Mammalian housekeeping genes evolve more slowly than tissue-specific genes. Mol Biol Evol 21:236-239.
15. Domazet-Lošo T, Tautz D (2010) A phylogenetically based transcriptome age index mirrors ontogenetic divergence patterns. Nature 468:815-818.
16. Duret L, Mouchiroud D (2000) Determinants of substitution rates in mammalian genes: Expression pattern affects selection intensity but not mutation rate. Mol Biol Evol 17:68-74. (Pubitemid 30056993)
17. Khaitovich P, et al. (2005) Parallel patterns of evolution in the genomes and transcriptomes of humans and chimpanzees. Science 309:1850-1854. (Pubitemid 41325094)