Crimean-Congo hemorrhagic fever virus nucleoprotein reveals endonuclease activity in bunyaviruses

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 13, 2012, Pages 5046-5051

  Guo, Yu ^a,b,c   Wang, Wenming ^b,c   Ji, Wei ^b,c   Deng, Maping ^d   Sun, Yuna ^e   Zhou, Honggang ^b,c   Yang, Cheng ^b,c   Deng, Fei ^d   Wang, Hualin ^d   Hu, Zhihong ^d   Lou, Zhiyong ^a   Rao, Zihe ^a,b,c,e  

^a TSINGHUA UNIVERSITY   (China)

^b NANKAI UNIVERSITY   (China)

^c WUHAN INSTITUTE OF VIROLOGY   (China)

^d Tianjin Joint Academy of Biomedicine and Technology   (China)

^e INSTITUTE OF BIOPHYSICS   (China)

Author keywords

Structure biology; Virology

Indexed keywords

ANTIVIRUS AGENT; ENDONUCLEASE; SINGLE STRANDED RNA; VIRUS NUCLEOPROTEIN;

ARTICLE; BUNYAVIRUS; CONTROLLED STUDY; CRIMEAN CONGO HEMORRHAGIC FEVER; CRYSTAL STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN STRUCTURE; RNA VIRUS; VIRUS MORPHOLOGY;

CHROMATOGRAPHY, GEL; CRYSTALLOGRAPHY, X-RAY; DNA, VIRAL; ENDONUCLEASES; HEMORRHAGIC FEVER VIRUS, CRIMEAN-CONGO; HOST-PATHOGEN INTERACTIONS; MODELS, MOLECULAR; NUCLEOPROTEINS; ORTHOBUNYAVIRUS; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RNA CAPS; RNA-BINDING PROTEINS; VIRAL PROTEINS;

BUNYAVIRIDAE; CRIMEAN-CONGO HEMORRHAGIC FEVER VIRUS; NAIROVIRUS; ORTHOBUNYAVIRUS; RNA VIRUSES;

EID: 84859452102     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1200808109     Document Type: Article

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