Relationship between diffusivity of water molecules inside hydrating tablets and their drug release behavior elucidated by magnetic resonance imaging

Chemical and Pharmaceutical Bulletin

Volumn 60, Issue 4, 2012, Pages 536-542

  Kikuchi, Shingo ^a   Onuki, Yoshinori ^a   Kuribayashi, Hideto ^b   Takayama, Kozo ^a  

^a HOSHI UNIVERSITY   (Japan)

^b YOKOGAWA ANALYTICAL SYSTEMS INC   (Japan)

Author keywords

Diffusion; Hydration; Magnetic resonance imaging; Sustained release; Swelling

Indexed keywords

DILTIAZEM; HYDROXYPROPYLMETHYLCELLULOSE; WATER;

ARTICLE; DIFFUSION WEIGHTED IMAGING; DRUG RELEASE; DRUG SOLUBILITY; MATRIX TABLET; NUCLEAR MAGNETIC RESONANCE IMAGING; TABLET FORMULATION; WATER PERMEABILITY;

CHEMISTRY, PHARMACEUTICAL; DIFFUSION; MAGNETIC RESONANCE IMAGING; METHYLCELLULOSE; TABLETS; WATER;

EID: 84859447516     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.60.536     Document Type: Article

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