Massive conformation change in the prion protein: Using dual-basin structure-based models to find misfolding pathways

Proteins: Structure, Function and Bioinformatics

Volumn 80, Issue 5, 2012, Pages 1299-1307

  Singh, Jesse P ^a   Whitford, Paul C ^b   Hayre, N R ^a   Onuchic, José ^c   Cox, Daniel L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b LOS ALAMOS NATIONAL LABORATORY   (United States)

^c RICE UNIVERSITY   (United States)

Author keywords

Beta helix; Disulfide; Left handed; Protein folding; Structure based

Indexed keywords

PRION PROTEIN;

ALPHA HELIX; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; FIBER; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN STRUCTURE;

DISULFIDES; HUMANS; MOLECULAR DYNAMICS SIMULATION; PRIONS; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STABILITY;

MAMMALIAN PRION;

EID: 84859443965     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.24026     Document Type: Article

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