Flt1 and Flk1 mediate regulation of intraocular pressure and their double heterozygosity causes the buphthalmia in mice

Biochemical and Biophysical Research Communications

Volumn 420, Issue 2, 2012, Pages 422-427

  Sano, Keigo ^a   Katsuta, Osamu ^b   Shirae, Satoshi ^b   Kubota, Yoshiaki ^c   Ema, Masatsugu ^d   Suda, Toshio ^c   Nakamura, Masatsugu ^b   Hirashima, Masanori ^a  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b SANTEN PHARMACEUTICAL CO LTD   (Japan)

^c KEIO UNIVERSITY   (Japan)

^d UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

Buphthalmia; Development; Endothelial cell; Intraocular pressure; Mouse; VEGF

Indexed keywords

COLLAGEN FIBER; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AQUEOUS HUMOR; ARTICLE; BUPHTHALMOS; CELL DEATH; CHOROID CAPILLARY LAYER; CONGENITAL GLAUCOMA; CONTROLLED STUDY; GENE INTERACTION; HETEROZYGOSITY; INTRAOCULAR PRESSURE; MATING; MOUSE; NERVE CELL; NONHUMAN; OPTIC DISK; PHENOTYPE; PRIORITY JOURNAL; SCHLEMM CANAL; SCLERA; WILD TYPE;

ANIMALS; HETEROZYGOTE; HYDROPHTHALMOS; INTRAOCULAR PRESSURE; MICE; MICE, MUTANT STRAINS; SCLERA; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

MUS;

EID: 84859422233     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.03.011     Document Type: Article

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