Novel PLA modification of organic microcontainers based on ring opening polymerization: Synthesis, characterization, biocompatibility and drug loading/release properties

International Journal of Pharmaceutics

Volumn 428, Issue 1-2, 2012, Pages 134-142

  Efthimiadou, E K ^a   Tziveleka, L A ^a   Bilalis, P ^a   Kordas, G ^a  

^a INSTITUTE OF MATERIALS SCIENCE   (Greece)

Author keywords

Daunorubicin; Drug delivery system; Hollow microspheres; pH response; PLA modification; Ring opening polymerization

Indexed keywords

2,2' AZOBISISOBUTYRONITRILE; ACRYLAMIDE DERIVATIVE; BUTYRONITRILE; DAUNORUBICIN; MICROSPHERE; POLY[HYDROXYETHYL METHACRYLATE CO N,N' METHYLENE BIS(ACRYLAMIDE)]; POLYLACTIC ACID; POLYMACON; POLYMETHACRYLIC ACID; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOCOMPATIBILITY; BREAST CANCER; CANCER CELL; CYTOTOXICITY; DISTILLATION; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG STABILITY; HUMAN; HUMAN CELL; HYDROLYSIS; POLYMERIZATION; PRECIPITATION; PRIORITY JOURNAL; RING OPENING; SYNTHESIS;

BIOCOMPATIBLE MATERIALS; CELL LINE, TUMOR; CHEMICAL PRECIPITATION; DAUNORUBICIN; DELAYED-ACTION PREPARATIONS; DISTILLATION; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; DRUG STABILITY; FEMALE; HUMANS; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; LACTIC ACID; MICROSPHERES; NITRILES; POLYHYDROXYETHYL METHACRYLATE; POLYMERIZATION; POLYMERS; WATER;

EID: 84859419784     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.02.030     Document Type: Article

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