Poly(DL-lactide-co-glycolide) nanospheres for the sustained release of folic acid

Journal of Biomedical Nanotechnology

Volumn 4, Issue 3, 2008, Pages 349-358

  Stevanović, Magdalena ^a   Radulović, Aleksandra ^b   Jordović, Branka ^c   Uskoković, Dragan ^a  

^a INSTITUTE OF TECHNICAL SCIENCES   (Serbia)

^b UNIVERSITY OF BELGRADE   (Serbia)

^c Faculty of Technical Sciences   (Serbia)

Author keywords

Drug delivery; Folic acid; IR; Nanoparticles; Poly(DL lactide co glycolide); SEM; Stereological analysis; UV Vis; Zeta potential measurements

Indexed keywords

ATOMIC SPECTROSCOPY; BIODEGRADABLE POLYMERS; DRUG DELIVERY; FUNCTIONAL POLYMERS; INFRARED SPECTROSCOPY; MOLECULAR SPECTROSCOPY; NANOPARTICLES; ORGANIC ACIDS; SCANNING ELECTRON MICROSCOPY; SPECTROSCOPIC ANALYSIS; SPECTRUM ANALYSIS; SURFACE ACTIVE AGENTS; ULTRAVIOLET SPECTROSCOPY; ZETA POTENTIAL;

FOLIC ACID; IR; POLY(DL-LACTIDE-CO-GLYCOLIDE); SEM; STEREOLOGICAL ANALYSIS; UV-VIS; ZETA POTENTIAL MEASUREMENTS;

CONTROLLED DRUG DELIVERY;

FOLIC ACID; LACTEL; MICROVIT; NANOPARTICLE; NANOSPHERE; POLYGLACTIN; POVIDONE; UNCLASSIFIED DRUG;

CONFERENCE PAPER; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; INFRARED SPECTROSCOPY; NANOENCAPSULATION; PARTICLE SIZE; PHYSICAL CHEMISTRY; SCANNING ELECTRON MICROSCOPY; STEREOMETRY; SUSTAINED DRUG RELEASE; SUSTAINED RELEASE FORMULATION; ULTRAVIOLET SPECTROSCOPY; ZETA POTENTIAL;

EID: 58149196373     PISSN: 15507033     EISSN: 15507041     Source Type: Journal    
DOI: 10.1166/jbn.2008.321     Document Type: Conference Paper

References (44)

1. H. Tamber, P. Johansen, H. P. Merkle, and B. Gander, Formulation aspects of biodegradable polymeric microspheres for antigen delivery. Advanced Drug Delivery Rev. 57, 357 (2005).
2. A. Braden, A. Kashyap, J. Vasir, V. Labhasetwar, and K. Vishwanatha, Polymeric nanoparticles for sustained down-regulation of annexin A2 lead to reduction in proliferation and migration of prostate cancer cells. J. Biomedical Nanotechnol. 3, 148 (2007).
3. E. Fournier, C. Passirani, C. N. Montero-Menei, and J. P. Benoit, Biocompatibility of implantable synthetic polymeric drug carriers: focus on brain biocompatibility. Biomaterials 24, 3311 (2003).
4. S. J. Siegel, J. B. Kahn, K. Metzger, K. I. Winey, K. Werner, and N. Dan, Efect of drug type on the degradation rate of PLGA matrices. European Journal of Pharmaceutics and Biopharmaceutics 64, 287 ( 2006).
5. D. Klose, F. Siepmann, K. Elkharraz, S. Krenzlin, and J. Siepmann, How porosity and size affect the drug release mechanisms from PLGA-based microparticles. Int. J. Pharm. 314, 198 (2006).
6. I. Bala, S. Hariharan, and M. N. V. Ravi Kumar, PLGA nanoparticles in drug delivery: The state of the art. Critical Reviews in Therapeutic Drug Carrier Systems 21, 387 (2004).
7. J. Cheng, B. A. Teply, I. Sheri, J. Sung, G. Luther, F. X. Gu, E. Levy-Nissenbaum, A. F. Radovic-Moreno, R. Langer, and O. C. Farokhzad, Formulation of functionalized PLGA-PEG nanoparticles for in vivo targeted drug delivery. Biomaterials 28, 869 (2007).
8. Y. Waeckerle-Men, E. Uetz-von Allmen, B. Gander, E. Scandella, E. Schlosser, G. Schmidtke, H. P. Merkle, and M. Groettrup, Encapsulation of proteins and peptides into biodegradable poly(d,l-lactide-co-glycolide) microspheres prolongs and enhances antigen presentation by human dendritic cells. Vaccine 24, 1847 (2006).
9. A. Matsumoto, Y. Matsukawa, T. Suzuki, and H. Yoshino, Drug release characteristics of multi-reservoir type microspheres with poly(dl-Iactide-co-glycolide) and poly(dl-lactide). J. Controlled Release 106, 172 (2005).
10. M. Vert, J. Mauduit, and S. Li, Biodegradation of PLA/GA polymers: increasing complexity. Biomaterials 15, 1209 (1994).
11. I. Grizzi, H. Garreau, S. Li, and M. Vert, Hydrolytic degradation of devices based on poly(DL-lactic acid) size-dependence. Biomaterials 16, 305 (1995).
12. H. K. Kim, H. J. Chung, and T. G. Park, Biodegradable polymeric microspheres with "open/closed" pores for sustained release of human growth hormone. J. Controlled Release 112, 167 (2006).
13. J. J. Lee, S.-G. Lee, J. C. Park, Y. II Yang, and J. K. Kim, Investigation on biodegradable PLGA scaffold with various pore size structure for skin tissue engineering. Current Applied Physics 7, e37-e40 (2007).
14. H. S. Yoo and T. G. Park, Folate receptor targeted biodegradable polymeric doxorubicin micelles. J. Controlled Release 96, 273 ( 2004).
15. M. E. Kafrissen and G. Oakley, Pharmaceutical Methods of Delivering Folic Acid, US Patent 6 190 693, February (2001).
16. N. Kanthamneni and S. Prabhu, Formulation development of targeted nanoparticle-based drug delivery systems for the chemoprevention of colon cancer. AAPS Annual Meeting and Exposition, November ( 2006).
17. L. Brannon-Peppas and J. O. Blanchette, Nanoparticle and targeted systems for cancer therapy. Advanced Drug Delivery Reviews 56, 1649 (2004).
18. F. X. Gu, R. Karnik, A. Z. Wang, F. Alexis, E. Levy-Nissenbaum, S. Hong, R. S. Langer, and O. C. Farokhzad, Targeted nanoparticles for cancer therapy. Nanotoday 2, 14 (2007).
19. A. C. Antony, The biological chemistry of folate receptors. Blood 79, 2807 (1992).
20. M. M. Stevanović, B. Jordović, and D. P. Uskoković, Preparation and characterization of poly(D,L-lactide-co-glycolide) nanoparticles containing ascorbic acid. Journal of Biomedicine and Biotechnology Article ID 84965 (2007).
21. H. E. Exner and H. P. Hougardy, Quantitative Image Analysis of Microstructures. DGM Informazions-Gesellschaft Gmbh Verlag, Germany ( 1988), pp. 11-12.
22. M. Stevanović, N. Ignjatović, B. Jordović, and D. Uskoković, Stereological analysis of the poly (DL-lactide-co-glycolide) submicron sphere prepared by solvent/ non-solvent chemical methods and centrifugal processing. J. Mater Sci. - Mater. Med. 18, 1339 (2007).
23. J. Zhang, S. Rana, R. S. Srivastava, and R. D. K. Misra, On the chemical and drug delivery response of folate receptor-activated, polyethylene glycol-funcionalized magnetite nanoparticles. Acta Biomaterialia 4, 40 (2008).
24. M. Stevanović, B. Jordović, Z. Nedić, and D. Milièević, The stabilizer influence on morphological characteristics of poly (DL-lactide-co-glycolide) nanospheres. Mater. Sci. Forum 555, 447 (2007).
25. J. Vandervoort and A. Ludvig, Biocompatibile stabilizers in the preparation of PLGA nanoparticles: a factorial design study. Int. J. Pharm. 238, 77 (2002).
26. P. N. Thanki, E. Dellacherie, and J.-L. Six, Surface characteristics of PLA and PLGA films. Appl. Surf. Sci. 253, 2758 (2006).
27. Y.-I. Jeong, Y.-H. Shim, K.-C. Song, Y.-G. Park, H.-W. Ryu, and J.-W. Nah, Testosterone-encapsulated surfactant-free nanoparticles of poly(DL-lactide-co-glycolide): preparation and release behavior. Bulletin Korean Chemical Society 23, 1579 (2002).
28. S. S. Feng and G. Huang, Effects of emulsifier on the controlled release of paclitaxel (Taxol R) from nanospheres of biodegradable polymers. J. Controlled Release 71, 53 (2001).
29. I. Jovanović, M. Stevanović, B. Nedeljković, and N. Ignjatović, The effect of processing parameters on characteristics of PLLA microspheres. Mater. Sci. Forum 555, 453 (2007).
30. L. Mu and S. S. Feng, PLGA/TPGS nanoparticles for controlled release of paclitaxel: Effects of the emulsifier and drug loading ratio. Pharm. Res. 20, 1864 (2003).
31. M. Stevanović, J. Savić, B. Jordović, and D. Uskoković, Fabrication, in vitro degradation and the release behaviours of poly(DL-lactide-co-glycolide) nanospheres containing ascorbic acid. Colloids Surf. B: Biointerfaces 59, 215 (2007).
32. G. P. Oakley, M. J. Adams, and C. M. Dickinson, More folic acid for everyone, now. J. Nutrition 126, 751 (1996).
33. M. Herrmann, J. P. Schmidt, N. Umanskaya, A. Wagner, O. Taban-Shomal, T. Widmann, G. Colaianni, B. Wildemann, and W. Herrmann, The role of hyperhomocysteinemia as well as folate, vitamin B(6) and B(12) deficiencies in osteoporosis - a systematic review. Clinical Chemistry and Laboratory Medicine 45, 1621 (2007).
34. P. Pathak, U. Kapil, C. S. Yajnik, S. K. Kapoor, S. N. Dwivedi, and R. Singh, Iron, folate, and vitamin B12 stores among pregnant women in a rural area of Haryana State, India. Food and Nutrition Bulletin 28, 435 (2007).
35. J. H. Park, S. Lee, J. H. Kim, K. Park, K. Kim, and I. C. Kwon, Polymeric nanonmedicine for cancer therapy. Prog. Polym. Sci. 33, 113 (2008).
36. R. Duncan, The dawning era of polymer therapeutics. Nat. Rev. Drug Discovery 2, 347 (2003).
37. J. Khandre and T. Minko, Polymer-drug conjugates: Progress in polymeric prodrugs. Prog. Polym. Sci. 31, 359 (2006).
38. H. McNulty, Folate requirements for health in different population groups. Br. J. Biomedical Sci. 52, 110 (1995).
39. Z. Zhang, S. H. Lee, and S.-S. Feng, Folate-decorated poly(lactide-co-glycolide)-vitamin E TPGS nanoparticles for targeted drug delivery. Biomaterials 28, 1889 (2007).
40. C. M. Paulos, J. A. Reddy, C. P. Leamon, M. J. Turk, and P S. Low, Ligand binding and kinetics of folate receptor recycling in vivo: Impact on receptor-mediated drug delivery. Mol. Pharmacol. 66, 1406 (2004).
41. Y. Hattori and Y. Maitani, Folate-linked nanoparticle-mediated suicide gene therapy in human prostate cancer and nasopharyngeal cancer with herpes simplex virus thymidine kinase. Cancer Gene Therapy 12, 796 (2005).
42. Y. Bae, W.-D. Jang, N. Nishiyama, S. Fukushima, and K. Kataoka, Multifunctional polymeric micelles with folate-mediated cancer cell targeting and pH-triggered drug releasing properties for active intracellular drug delivery. Molecular Biosystems 1, 242 (2005).
43. J. Sudimack and R. J. Lee, Targeted drug delivery via the folate receptor. Advances Drug Delivery Reviews 41, 147 (2000).
44. A. Moore, J. P. Basilion, E. A. Chiocca, and R. Weissleder, Measuring transferrin receptor gene expression by NMR imaging. Biochimica et Biophysica Acta 1402, 239 (1998).