Surprising unreactivity of cholesterol-5,6-epoxides towards nucleophiles

Journal of Lipid Research

Volumn 53, Issue 4, 2012, Pages 718-725

  Paillasse, Michael R ^a,b   Saffon, Nathalie ^c   Gornitzka, Heinz ^d   Silvente Poirot, Sandrine ^a   Poirot, Marc ^a   De Medina, Philippe ^a,b  

^a CANCER RESEARCH CENTER OF TOULOUSE   (France)

^b Affichem   (France)

^c Université Paul Sabatier   (France)

^d LCC LABORATOIRE DE CHIMIE DE COORDINATION   (France)

Author keywords

Alkylation; Cholesterol oxides; Ring opening; S N2

Indexed keywords

2 (2 HYDROXYETHYLAMINO) 2 PHENYLETHANOL; 2 (2 HYDROXYETHYLSULFANYL) 2 PHENYLETHANOL; 2 (7 GUANIDYL) 2 PHENYLETHANOL; CHOLESTEROL 5,6 EPOXIDE HYDROLASE DERIVATIVE; EPOXIDE HYDROLASE; NUCLEOPHILE; PHENETHYL ALCOHOL; STYRENE OXIDE; UNCLASSIFIED DRUG;

AMINOLYSIS; ARTICLE; CATALYSIS; CONFORMATION; CRYSTALLIZATION; CRYSTALLOGRAPHY; DENSITOMETRY; DIASTEREOISOMER; ENVIRONMENTAL TEMPERATURE; ENZYME SYNTHESIS; MOLECULAR MODEL; MUTAGENICITY; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STEREOCHEMISTRY; STRUCTURE ANALYSIS; THIN LAYER CHROMATOGRAPHY; X RAY DIFFRACTION;

ALKYLATION; CATALYSIS; CHOLESTEROL; CRYSTALLOGRAPHY, X-RAY; CULTURE MEDIA; EPOXY COMPOUNDS; ETHANOLAMINE; GUANINE; MERCAPTOETHANOL; MODELS, MOLECULAR; STEREOISOMERISM;

EID: 84859385107     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M023689     Document Type: Article

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