-
1
-
-
0037129380
-
Nonalcoholic Fatty Liver Disease
-
Angulo P (2002) Nonalcoholic Fatty Liver Disease. N Engl J Med 346: 1221-1231.
-
(2002)
N Engl J Med
, vol.346
, pp. 1221-1231
-
-
Angulo, P.1
-
2
-
-
14644435731
-
Reversal of nonalcoholic hepatic steatosis, hepatic insulin resistance, and hyperglycemia by moderate weight reduction in patients with type 2 diabetes
-
Petersen KF, Dufour S, Befroy D, Lehrke M, Hendler RE, et al. (2005) Reversal of nonalcoholic hepatic steatosis, hepatic insulin resistance, and hyperglycemia by moderate weight reduction in patients with type 2 diabetes. Diabetes 54: 603-608.
-
(2005)
Diabetes
, vol.54
, pp. 603-608
-
-
Petersen, K.F.1
Dufour, S.2
Befroy, D.3
Lehrke, M.4
Hendler, R.E.5
-
3
-
-
0036114844
-
Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy
-
Petersen KF, Oral EA, Dufour S, Befroy D, Ariyan C, et al. (2002) Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy. J Clin Invest 109: 1345-1350.
-
(2002)
J Clin Invest
, vol.109
, pp. 1345-1350
-
-
Petersen, K.F.1
Oral, E.A.2
Dufour, S.3
Befroy, D.4
Ariyan, C.5
-
4
-
-
49449092403
-
Identification and characterization of metabolically benign obesity in humans
-
Stefan N, Kantartzis K, Machann J, Schick F, Thamer C, et al. (2008) Identification and characterization of metabolically benign obesity in humans. Arch Intern Med 168: 1609-1616.
-
(2008)
Arch Intern Med
, vol.168
, pp. 1609-1616
-
-
Stefan, N.1
Kantartzis, K.2
McHann, J.3
Schick, F.4
Thamer, C.5
-
5
-
-
70349326750
-
Intrahepatic fat, not visceral fat, is linked with metabolic complications of obesity
-
Fabbrini E, Magkos F, Mohammed BS, Pietka T, Abumrad NA, et al. (2009) Intrahepatic fat, not visceral fat, is linked with metabolic complications of obesity. Proc Natl Acad Sci U S A 106: 15430-15435.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 15430-15435
-
-
Fabbrini, E.1
Magkos, F.2
Mohammed, B.S.3
Pietka, T.4
Abumrad, N.A.5
-
7
-
-
34548395788
-
Macrophage TNF-alpha contributes to insulin resistance and hepatic steatosis in diet-induced obesity
-
De Taeye BM, Novitskaya T, McGuinness OP, Gleaves L, Medda M, et al. (2007) Macrophage TNF-alpha contributes to insulin resistance and hepatic steatosis in diet-induced obesity. Am J Physiol Endocrinol Metab 293: E713-725.
-
(2007)
Am J Physiol Endocrinol Metab
, vol.293
-
-
De Taeye, B.M.1
Novitskaya, T.2
McGuinness, O.P.3
Gleaves, L.4
Medda, M.5
-
8
-
-
77953868236
-
Lipid-induced insulin resistance: Unravelling the mechanism
-
Samuel VT, Petersen KF, Shulman GI (2010) Lipid-induced insulin resistance: unravelling the mechanism. Lancet 375: 2267-2277.
-
(2010)
Lancet
, vol.375
, pp. 2267-2277
-
-
Samuel, V.T.1
Petersen, K.F.2
Shulman, G.I.3
-
9
-
-
80053099430
-
A mouse model for nonalcoholic steatohepatitis
-
Sundaresan S, Vijayagopal P, Mills N, Imrhan V, Prasad C (2011) A mouse model for nonalcoholic steatohepatitis. J Nutr Biochem 22: 979-984.
-
(2011)
J Nutr Biochem
, vol.22
, pp. 979-984
-
-
Sundaresan, S.1
Vijayagopal, P.2
Mills, N.3
Imrhan, V.4
Prasad, C.5
-
10
-
-
5444240778
-
Hepatic gene expression profiles in a long-term high-fat diet-induced obesity mouse model
-
Kim S, Sohn I, Ahn JI, Lee KH, Lee YS (2004) Hepatic gene expression profiles in a long-term high-fat diet-induced obesity mouse model. Gene 340: 99-109.
-
(2004)
Gene
, vol.340
, pp. 99-109
-
-
Kim, S.1
Sohn, I.2
Ahn, J.I.3
Lee, K.H.4
Lee, Y.S.5
-
11
-
-
79960258887
-
Aging and obesity induce distinct gene expression adaptation in the liver of C57BL/6J Mice
-
Capel F, Delmotte MH, Brun M, Lonchampt M, De Fanti B, et al. (2011) Aging and obesity induce distinct gene expression adaptation in the liver of C57BL/6J Mice. J Nutrigenet Nutrigenomics 4: 154-164.
-
(2011)
J Nutrigenet Nutrigenomics
, vol.4
, pp. 154-164
-
-
Capel, F.1
Delmotte, M.H.2
Brun, M.3
Lonchampt, M.4
De Fanti, B.5
-
12
-
-
77956662142
-
Hepatic transcription response to high-fat treatment in mice: Microarray comparison of individual vs. pooled RNA samples
-
Do GM, Kwon EY, Kim E, Kim HS, Choi MS (2010) Hepatic transcription response to high-fat treatment in mice: microarray comparison of individual vs. pooled RNA samples. Biotechnol J 5: 970-973.
-
(2010)
Biotechnol J
, vol.5
, pp. 970-973
-
-
Do, G.M.1
Kwon, E.Y.2
Kim, E.3
Kim, H.S.4
Choi, M.S.5
-
13
-
-
34748845043
-
Phosphorylation of human insulin receptor substrate-1 at Serine 629 plays a positive role in insulin signaling
-
Luo M, Langlais P, Yi Z, Lefort N, De Filippis EA, et al. (2007) Phosphorylation of human insulin receptor substrate-1 at Serine 629 plays a positive role in insulin signaling. Endocrinology 148: 4895-4905.
-
(2007)
Endocrinology
, vol.148
, pp. 4895-4905
-
-
Luo, M.1
Langlais, P.2
Yi, Z.3
Lefort, N.4
De Filippis, E.A.5
-
14
-
-
33645128928
-
Quantification of phosphorylation of insulin receptor substrate-1 by HPLC-ESI-MS/MS
-
Yi Z, Luo M, Mandarino LJ, Reyna SM, Carroll CA, et al. (2006) Quantification of phosphorylation of insulin receptor substrate-1 by HPLC-ESI-MS/MS. J Am Soc Mass Spectrom 17: 562-567.
-
(2006)
J Am Soc Mass Spectrom
, vol.17
, pp. 562-567
-
-
Yi, Z.1
Luo, M.2
Mandarino, L.J.3
Reyna, S.M.4
Carroll, C.A.5
-
15
-
-
77449155964
-
Proteomics analysis of human skeletal muscle reveals novel abnormalities in obesity and type 2 diabetes
-
Hwang H, Bowen BP, Lefort N, Flynn CR, De Filippis EA, et al. (2010) Proteomics analysis of human skeletal muscle reveals novel abnormalities in obesity and type 2 diabetes. Diabetes 59: 33-42.
-
(2010)
Diabetes
, vol.59
, pp. 33-42
-
-
Hwang, H.1
Bowen, B.P.2
Lefort, N.3
Flynn, C.R.4
De Filippis, E.A.5
-
16
-
-
77951286204
-
Recent advances in nonalcoholic fatty liver disease
-
Cheung O, Sanyal AJ (2010) Recent advances in nonalcoholic fatty liver disease. Curr Opin Gastroenterol 26: 202-208.
-
(2010)
Curr Opin Gastroenterol
, vol.26
, pp. 202-208
-
-
Cheung, O.1
Sanyal, A.J.2
-
17
-
-
0019152816
-
Nonalcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease
-
Ludwig J, Viggiano TR, McGill DB, Oh BJ (1980) Nonalcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease. Mayo Clin Proc 55: 434-438.
-
(1980)
Mayo Clin Proc
, vol.55
, pp. 434-438
-
-
Ludwig, J.1
Viggiano, T.R.2
McGill, D.B.3
Oh, B.J.4
-
18
-
-
77955500907
-
Dietary fat intake promotes the development of hepatic steatosis independently from excess caloric consumption in a murine model
-
de Meijer VE, Le HD, Meisel JA, Akhavan Sharif MR, Pan A, et al. (2010) Dietary fat intake promotes the development of hepatic steatosis independently from excess caloric consumption in a murine model. Metabolism 59: 1092-1105.
-
(2010)
Metabolism
, vol.59
, pp. 1092-1105
-
-
de Meijer, V.E.1
Le, H.D.2
Meisel, J.A.3
Akhavan Sharif, M.R.4
Pan, A.5
-
19
-
-
78649963675
-
Integrated hepatic transcriptome and proteome analysis of mice with high-fat diet-induced nonalcoholic fatty liver disease
-
Kirpich IA, Gobejishvili LN, Bon Homme M, Waigel S, Cave M, et al. (2011) Integrated hepatic transcriptome and proteome analysis of mice with high-fat diet-induced nonalcoholic fatty liver disease. J Nutr Biochem 22: 38-45.
-
(2011)
J Nutr Biochem
, vol.22
, pp. 38-45
-
-
Kirpich, I.A.1
Gobejishvili, L.N.2
Bon, H.M.3
Waigel, S.4
Cave, M.5
-
20
-
-
78149293577
-
Functional Comparison of Esterified and Free Forms of Conjugated Linoleic Acid in High-Fat-Diet-Induced Obese C57BL/6J Mice
-
Kim JH, Pan JH, Park HG, Yoon HG, Kwon OJ, et al. (2010) Functional Comparison of Esterified and Free Forms of Conjugated Linoleic Acid in High-Fat-Diet-Induced Obese C57BL/6J Mice. J Agric Food Chem.
-
(2010)
J Agric Food Chem.
-
-
Kim, J.H.1
Pan, J.H.2
Park, H.G.3
Yoon, H.G.4
Kwon, O.J.5
-
21
-
-
70149108302
-
Leptin contributes to the adaptive responses of mice to high-fat diet intake through suppressing the lipogenic pathway
-
Jiang L, Wang Q, Yu Y, Zhao F, Huang P, et al. (2009) Leptin contributes to the adaptive responses of mice to high-fat diet intake through suppressing the lipogenic pathway. PLoS One 4: e6884.
-
(2009)
PLoS One
, vol.4
-
-
Jiang, L.1
Wang, Q.2
Yu, Y.3
Zhao, F.4
Huang, P.5
-
22
-
-
47349098124
-
Proteomic analysis of fructose-induced fatty liver in hamsters
-
Zhang L, Perdomo G, Kim DH, Qu S, Ringquist S, et al. (2008) Proteomic analysis of fructose-induced fatty liver in hamsters. Metabolism 57: 1115-1124.
-
(2008)
Metabolism
, vol.57
, pp. 1115-1124
-
-
Zhang, L.1
Perdomo, G.2
Kim, D.H.3
Qu, S.4
Ringquist, S.5
-
23
-
-
66449096802
-
Identification of MUP1 as a regulator for glucose and lipid metabolism in mice
-
Zhou Y, Jiang L, Rui L (2009) Identification of MUP1 as a regulator for glucose and lipid metabolism in mice. J Biol Chem 284: 11152-11159.
-
(2009)
J Biol Chem
, vol.284
, pp. 11152-11159
-
-
Zhou, Y.1
Jiang, L.2
Rui, L.3
-
24
-
-
67649774119
-
Major urinary protein-1 increases energy expenditure and improves glucose intolerance through enhancing mitochondrial function in skeletal muscle of diabetic mice
-
Hui X, Zhu W, Wang Y, Lam KS, Zhang J, et al. (2009) Major urinary protein-1 increases energy expenditure and improves glucose intolerance through enhancing mitochondrial function in skeletal muscle of diabetic mice. J Biol Chem 284: 14050-14057.
-
(2009)
J Biol Chem
, vol.284
, pp. 14050-14057
-
-
Hui, X.1
Zhu, W.2
Wang, Y.3
Lam, K.S.4
Zhang, J.5
-
25
-
-
78649321933
-
Genetic, structural and biochemical basis of carbamoyl phosphate synthetase 1 deficiency
-
Martinez AI, Perez-Arellano I, Pekkala S, Barcelona B, Cervera J (2010) Genetic, structural and biochemical basis of carbamoyl phosphate synthetase 1 deficiency. Mol Genet Metab 101: 311-323.
-
(2010)
Mol Genet Metab
, vol.101
, pp. 311-323
-
-
Martinez, A.I.1
Perez-Arellano, I.2
Pekkala, S.3
Barcelona, B.4
Cervera, J.5
-
26
-
-
0034280340
-
Ornithine aminotransferase, a potential target for the treatment of hyperammonemias
-
Seiler N (2000) Ornithine aminotransferase, a potential target for the treatment of hyperammonemias. Curr Drug Targets 1: 119-153.
-
(2000)
Curr Drug Targets
, vol.1
, pp. 119-153
-
-
Seiler, N.1
-
27
-
-
48149111676
-
The moonlighting enzyme CD13: Old and new functions to target
-
Mina-Osorio P (2008) The moonlighting enzyme CD13: old and new functions to target. Trends Mol Med 14: 361-371.
-
(2008)
Trends Mol Med
, vol.14
, pp. 361-371
-
-
Mina-Osorio, P.1
-
28
-
-
79951698213
-
Aminopeptidase N (CD13) as a target for cancer chemotherapy
-
Wickstrom M, Larsson R, Nygren P, Gullbo J (2011) Aminopeptidase N (CD13) as a target for cancer chemotherapy. Cancer Sci 102: 501-508.
-
(2011)
Cancer Sci
, vol.102
, pp. 501-508
-
-
Wickstrom, M.1
Larsson, R.2
Nygren, P.3
Gullbo, J.4
-
29
-
-
1342323614
-
Fatty aldehyde dehydrogenase: Potential role in oxidative stress protection and regulation of its gene expression by insulin
-
Demozay D, Rocchi S, Mas JC, Grillo S, Pirola L, et al. (2004) Fatty aldehyde dehydrogenase: potential role in oxidative stress protection and regulation of its gene expression by insulin. J Biol Chem 279: 6261-6270.
-
(2004)
J Biol Chem
, vol.279
, pp. 6261-6270
-
-
Demozay, D.1
Rocchi, S.2
Mas, J.C.3
Grillo, S.4
Pirola, L.5
-
30
-
-
5644231992
-
Endoplasmic reticulum stress links obesity, insulin action and type 2 diabetes
-
Ozcan U, Cao Q, Yilmaz E, Lee AH, Iwakoshi NN, et al. (2004) Endoplasmic reticulum stress links obesity, insulin action and type 2 diabetes. Science 306: 457-461.
-
(2004)
Science
, vol.306
, pp. 457-461
-
-
Ozcan, U.1
Cao, Q.2
Yilmaz, E.3
Lee, A.H.4
Iwakoshi, N.N.5
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