An efficient way from naringenin to carthamidine and isocarthamidine by Aspergillus niger

World Journal of Microbiology and Biotechnology

Volumn 28, Issue 4, 2012, Pages 1803-1806

  Xu, Jing ^a,b   Yang, Li ^a   Zhao, Shu Juan ^a   Wang, Zheng Tao ^a,b   Hu, Zhi Bi ^a  

^a SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Aspergillus niger; Biotransformation; Carthamidin; Hydroxylation; Isocarthamidin; Naringenin

Indexed keywords

ASPERGILLUS NIGER; BIOTRANSFORMATION; CARTHAMIDIN; ISOCARTHAMIDIN; NARINGENIN;

ASPERGILLUS; BIOCONVERSION; CONVERSION EFFICIENCY; HYDROXYLATION; THIN LAYER CHROMATOGRAPHY;

ORGANIC COMPOUNDS;

ANTIOXIDANT; CARTHAMIDIN; FLAVANONE DERIVATIVE; NARINGENIN;

ARTICLE; ASPERGILLUS NIGER; BIOTRANSFORMATION; HYDROXYLATION; MASS SPECTROMETRY; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; TIME;

ANTIOXIDANTS; ASPERGILLUS NIGER; BIOTRANSFORMATION; FLAVANONES; HYDROXYLATION; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; TIME FACTORS;

ASPERGILLUS NIGER;

EID: 84859269711     PISSN: 09593993     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11274-011-0934-9     Document Type: Article

References (16)

1. Cotelle N (2001) Role of flavonoids in oxidative stress. Curr Top Med Chem 1: 569-590.
2. Goh D, Lee YH, Ong ES (2005) Inhibitory effects of a chemically standardized extract from Scutellaria barbata in human colon cancer cell lines, LoVo. J Agric Food Chem 53: 8197-8204.
3. Gu L, Wu T, Wang Z (2009) TLC bioautography-guided isolation of antioxidants from fruit of Perilla frutescens var. acuta. LWT-Food Sci Technol 42: 131-136.
4. Heim KE, Tagliaferro AR, Bobilya DJ (2002) Flavonoid antioxidants: chemistry, metabolism and structure-activity relationships. J Nutr Biochem 13: 572-584.
5. Hodek P, Trefil P, Stiborova M (2002) Flavonoids-potent and versatile biologically active compounds interacting with cytochromes P450. Chem-Biol Interact 139: 1-21.
6. Horvath CR, Martos PA, Saxena PK (2005) Identification and quantification of eight flavones in root and shoot tissues of the medicinal plant Huang-qin (Scutellaria baicalensis Georgi) using high-performance liquid chromatography with diode array and mass spectrometric detection. J Chromatogr A 1062: 199-207.
7. Iwashita K, Kobori M, Yamaki K, Tsushida T (2000) Flavonoids inhibit cell growth and induce apoptosis in B16 melanoma 4A5 cells. Biosci Biotech Biochem 64: 1813-1820.
8. Jin Y, Xiao Y, Zhang F, Xue X, Xu Q, Liang X (2008) Systematic screening and characterization of flavonoid glycosides in Carthamus tinctorius L. by liquid chromatography/UV diode-array detection/electrospray ionization tandem mass spectrometry. J Pharmaceut Biomed 46: 418-430.
9. Kawaii S, Tomono Y, Katase E, Ogawa K, Yano M (1999) Quantitation of flavonoid constituents in citrus fruits. J Agric Food Chem 47: 3565-3571.
10. Kuo SM (1996) Antiproliferative potency of structurally distinct dietary flavonoids on human colon cancer cells. Cancer Lett 110: 41-48.
11. Miyake Y, Yamamoto K, Morimitsu Y, Osawa T (1998) Characteristics of antioxidative flavonoid glycosides in lemon fruit. Food Sci Technol Int 4: 48-53.
12. Miyake Y, Minato K, Fukumoto S, Yamamoto K, Oya-Ito T, Kawakishi S, Osawa T (2003) New potent antioxidative hydroxyflavanones produced with Aspergillus saitoi from flavanone glycoside in citrus fruit. Biosci Biotech Biochem 67: 1443-1450.
13. Obara H, Onodera J, Kurihara Y, Yamamoto F (1978) Synthesis of 2′, 3′, 4, 4′, 6′-pentahydroxychalcone, an aglycone of carthamin, and its isomerization into 4′, 5, 6, 7-and 4′, 5, 7, 8-tetrahydroxyflavanone, carthamidin and isocarthamidin. B Chem Soc Jpn 51: 3627-3630.
14. Tiwari AK (2001) Imbalance in antioxidant defense and human diseases: multiple approach of natural antioxidants therapy. Curr Sci 81: 1179-1187.
15. Werawattanachai N, Kaewamatawong R (2010) Chemical constituents from Parinari anamense. Biochem Syst Ecol 38: 836-838.
16. Wu JH, Wang XH, Yi YH, Lee KH (2003) Anti-AIDS agents 54. A potent anti-HIV chalcone and flavonoids from genus Desmos. Bioorg Med Chem Lett 13: 1813-1815.