The immune cell composition in Barrett's metaplastic tissue resembles that in normal duodenal tissue

PLoS ONE

Volumn 7, Issue 4, 2012, Pages

  Lind, Alexandra ^a   Siersema, Peter D ^a   Kusters, Johannes G ^a   van der Linden, Jan A M ^a   Knol, Edward F ^a   Koenderman, Leo ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CD103 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; GRANZYME B; INTERLEUKIN 4; MESSENGER RNA; MUCOSAL ADDRESSIN CELL ADHESION MOLECULE 1; PROTEIN ALPHA4BETA7; T LYMPHOCYTE ANTIGEN; UNCLASSIFIED DRUG; ALPHA E INTEGRINS; ALPHA INTEGRIN; ALPHA4 INTEGRIN; BETA INTEGRIN; BETA7 INTEGRIN; CD3 ANTIGEN; GRANZYME; IMMUNOGLOBULIN; LEUKOCYTE ANTIGEN; MADCAM1 PROTEIN, HUMAN; MUCOPROTEIN;

ADULT; ARTICLE; BARRETT ESOPHAGUS; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL COMPOSITION; CLINICAL ARTICLE; CONTROLLED STUDY; DUODENUM; EOSINOPHIL; ESOPHAGUS BIOPSY; EX VIVO STUDY; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCOMPETENT CELL; IMMUNOHISTOCHEMISTRY; INTESTINE METAPLASIA; MALE; PHENOTYPE; PROTEIN EXPRESSION; SCANNING ELECTRON MICROSCOPY; TH2 CELL; CASE CONTROL STUDY; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; METABOLISM; METAPLASIA; MIDDLE AGED; MUCOSA; PATHOLOGY; T LYMPHOCYTE;

ANTIGENS, CD; ANTIGENS, CD3; BARRETT ESOPHAGUS; CASE-CONTROL STUDIES; CD4-POSITIVE T-LYMPHOCYTES; DUODENUM; EOSINOPHILS; FEMALE; GENE EXPRESSION REGULATION; GRANZYMES; HUMANS; IMMUNOGLOBULINS; INTEGRIN ALPHA CHAINS; INTEGRIN ALPHA4; INTEGRIN BETA CHAINS; MALE; METAPLASIA; MIDDLE AGED; MUCOPROTEINS; MUCOUS MEMBRANE; RNA, MESSENGER; T-LYMPHOCYTES;

EID: 84859227706     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0033899     Document Type: Article

References (40)

1. Pohl H, Welch HG, (2005) The role of overdiagnosis and reclassification in the marked increase of esophageal adenocarcinoma incidence. J Natl Cancer Inst 97: 142.
2. Spechler SJ, (1999) Barrett's esophagus. Curr Opin Gastroenterol 15: 352.
3. Rastogi AS, Puli HB, El-Serag A, Bansal S, Wani, et al. (2008) Incidence of esophageal adenocarcinoma in patients with Barrett's esophagus and high-grade dysplasia: a meta-analysis. Gastrointest Endosc 67: 394.
4. Whittles CELR, Biddlestone A, Burton H, Barr JA, Jankowski PJ, et al. (1999) Apoptotic and proliferative activity in the neoplastic progression of Barrett's oesophagus: a comparative study. J Pathol 187: 535.
5. Wang KK, Sampliner RE, (2008) Updated guidelines 2008 for the diagnosis, surveillance and therapy of Barrett's esophagus. Am J Gastroenterol 103: 788.
6. Bobryshev YV, Tran D, Killingsworth MC, Buckland M, Lord RV, (2009) Dendritic cells in Barrett's esophagus and esophageal adenocarcinoma. J Gastrointest Surg 13: 44.
7. Moons LM, Kusters JG, Bultman E, Kuipers EJ, van WM, Tra DH, et al. (2005) Barrett's oesophagus is characterized by a predominantly humoral inflammatory response. J Pathol 207: 269.
8. Armstrong D, Bennett JR, Blum AL, Dent J, De Dombal FT, et al. (1996) The endoscopic assessment of esophagitis: a progress report on observer agreement. Gastroenterology 111: 85.
9. Kulaylat MN, Dayton MT, (2010) Ulcerative colitis and cancer. J Surg Oncol 101: 706.
10. Terzic J, Grivennikov S, Karin E, Karin M, (2010) Inflammation and colon cancer. Gastroenterology 138: 2101.
11. Fitzgerald RC, Onwuegbusi BA, Bajaj-Elliott M, Saeed IT, Burnham WR, et al. (2002) Diversity in the oesophageal phenotypic response to gastro-oesophageal reflux: immunological determinants. Gut 50: 451.
12. Agace W, (2010) Generation of gut-homing T cells and their localization to the small intestinal mucosa. Immunol Lett 128: 21.
13. Fitzgerald RC, Abdalla S, Onwuegbusi BA, Sirieix P, Saeed IT, et al. (2002) Inflammatory gradient in Barrett's oesophagus: implications for disease complications. Gut 51: 316.
14. Clark RA, Chong BF, Mirchandani N, Yamanaka K, Murphy GF, et al. (2006) A novel method for the isolation of skin resident T cells from normal and diseased human skin. J Invest Dermatol 126: 1059.
15. Koch SD, Uss E, van Lier RA, ten Berge IJ, (2008) Alloantigen-induced regulatory CD8+CD103+ T cells. Hum Immunol 69: 737.
16. Zuo L, Rothenberg ME, (2007) Gastrointestinal eosinophilia. Immunol Allergy Clin North Am 27: 443.
17. Conus S, Straumann A, Bettler E, Simon HU, (2010) Mepolizumab does not alter levels of eosinophils, T cells, and mast cells in the duodenal mucosa in eosinophilic esophagitis. J Allergy Clin Immunol 126: 175.
18. Campos LE, Pereira LF, (2009) Pulmonary eosinophilia. J Bras Pneumol 35: 561.
19. Chehade M, Aceves SS, (2010) Food allergy and eosinophilic esophagitis. Curr Opin Allergy Clin Immunol 10: 231.
20. El-Khayat HR, El KA, Nosseir M, Ezz MA, El-Amin H, et al. (2010) Portal hypertensive enteropathy before and after variceal obliteration: an endoscopic, histopathologic and immunohistochemical study. J Gastrointestin Liver Dis 19: 175.
21. Becker V, Vieth M, Bajbouj M, Schmid RM, Meining A, (2008) Confocal laser scanning fluorescence microscopy for in vivo determination of microvessel density in Barrett's esophagus. Endoscopy 40: 888.
22. Augustin MT, Kokkonen J, Karttunen TJ, (2005) Duodenal cytotoxic lymphocytes in cow's milk protein sensitive enteropathy and coeliac disease. Scand J Gastroenterol 40: 1398.
23. Denucci CC, Mitchell JS, Shimizu Y, (2009) Integrin function in T-cell homing to lymphoid and nonlymphoid sites: getting there and staying there. Crit Rev Immunol 29: 87.
24. Cornes JS, (1965) Number, size, and distribution of Peyer's patches in the human small intestine: Part I The development of Peyer's patches. Gut 6: 225.
25. Prasad KK, Thapa BR, Nain CK, Singh K, (2010) The frequency of histologic lesion variability of the duodenal mucosa in children with celiac disease. World J Pediatr 6: 60.
26. Vogelsang H, Hanel S, Steiner B, Oberhuber G, (2001) Diagnostic duodenal bulb biopsy in celiac disease. Endoscopy 33: 336.
27. Paul WE, Seder RA, (1994) Lymphocyte responses and cytokines. Cell 76: 241.
28. Fernandez S, Molina IJ, Romero P, Gonzalez R, Pena J, et al. (2011) Characterization of gliadin-specific th17 cells from the mucosa of celiac disease patients. Am J Gastroenterol 106: 528.
29. Zingg U, Montani M, Frey DM, Dirnhofer S, Esterman AJ, et al. (2010) Tumour-infiltrating lymphocytes and survival in patients with adenocarcinoma of the oesophagus. Eur J Surg Oncol 36: 670.
30. Afonina IS, Cullen SP, Martin SJ, (2010) Cytotoxic and non-cytotoxic roles of the CTL/NK protease granzyme B. Immunol Rev 235: 105.
31. Cepek KL, Shaw SK, Parker CM, Russell GJ, Morrow JS, et al. (1994) Adhesion between epithelial cells and T lymphocytes mediated by E-cadherin and the alpha E beta 7 integrin. Nature 372: 190.
32. Smyth LJ, Eustace A, Kolsum U, Blaikely J, Singh D, (2010) Increased airway T regulatory cells in asthmatic subjects. Chest 138: 905.
33. Ho J, Kurtz CC, Naganuma M, Ernst PB, Cominelli F, et al. (2008) A CD8+/CD103high T cell subset regulates TNF-mediated chronic murine ileitis. J Immunol 180: 2573.
34. Sather BD, Treuting P, Perdue N, Miazgowicz M, Fontenot JD, et al. (2007) Altering the distribution of Foxp3(+) regulatory T cells results in tissue-specific inflammatory disease. J Exp Med 204: 1335.
35. Anz D, Mueller W, Golic M, Kunz WG, Rapp M, (2011) CD103 is a hallmark of tumor-infiltrating regulatory T cells. Int J Cancer 129 (10): 2417-26.
36. Farstad IN, Halstensen TS, Lien B, Kilshaw PJ, Lazarovits AI, et al. (1996) Distribution of beta 7 integrins in human intestinal mucosa and organized gut-associated lymphoid tissue. Immunology 89: 227.
37. Onwuegbusi BA, Aitchison A, Chin SF, Kranjac T, Mills I, et al. (2006) Impaired transforming growth factor beta signalling in Barrett's carcinogenesis due to frequent SMAD4 inactivation. Gut 55: 764.
38. Perez-Machado MA, Ashwood P, Thomson MA, Latcham F, Sim R, et al. (2003) Reduced transforming growth factor-beta1-producing T cells in the duodenal mucosa of children with food allergy. Eur J Immunol 33: 2307.
39. Grose RH, Cummins AG, Thompson FM, (2007) Deficiency of invariant natural killer T cells in coeliac disease. Gut 56: 790.
40. Armstrong D, (2004) Review article: towards consistency in the endoscopic diagnosis of Barrett's oesophagus and columnar metaplasia. Aliment Pharmacol Ther 20 (Suppl 5): 40.