Unique cell type-specific junctional complexes in vascular endothelium of human and rat liver sinusoids

PLoS ONE

Volumn 7, Issue 4, 2012, Pages

  Géraud, Cyrill ^a   Evdokimov, Konstantin ^a   Straub, Beate K ^b   Peitsch, Wiebke K ^a   Demory, Alexandra ^a   Dörflinger, Yvette ^a   Schledzewski, Kai ^a   Schmieder, Astrid ^a   Schemmer, Peter ^c   Augustin, Hellmut G ^c,d   Schirmacher, Peter ^b   Goerdt, Sergij ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA CATENIN; BETA CATENIN; CADHERIN; CELL MEMBRANE PROTEIN; CELL RECEPTOR; CLAUDIN 5; FC RECEPTOR IIB; JUNCTIONAL ADHESION MOLECULE A; MANNOSE RECEPTOR; OCCLUDIN; PLAKOGLOBIN; PROTEIN JAM B; PROTEIN JAM C; PROTEIN P120; PROTEIN ZO1; PROTEIN ZO2; STABILIN 1 PROTEIN; STABILIN 2 PROTEIN; UNCLASSIFIED DRUG; CELL ADHESION MOLECULE; CLAUDIN; CLDN5 PROTEIN, HUMAN; JAM3 PROTEIN, HUMAN; LEUKOCYTE ANTIGEN; MEMBRANE PROTEIN; VASCULAR ENDOTHELIAL CADHERIN;

ADULT; AGED; ANIMAL CELL; ARTICLE; BLOOD VESSEL PERMEABILITY; CELL FUNCTION; CELL JUNCTION; CELL MIGRATION; CELL SPECIFICITY; CELL TYPE; CLINICAL ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; FEMALE; HEPATITIS; HUMAN; HUMAN TISSUE; IMMUNOREACTIVITY; LIVER METASTASIS; LIVER SINUSOID; LYMPH VESSEL ENDOTHELIUM; MALE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN STRUCTURE; RAT; TIGHT JUNCTION; VASCULAR ENDOTHELIUM; ANIMAL; ANTIBODY SPECIFICITY; BLOOD VESSEL; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; LIVER; LIVER DISEASE; METABOLISM; MIDDLE AGED; PATHOLOGY; PROTEIN TRANSPORT; SPRAGUE DAWLEY RAT; TUMOR CELL LINE; VASCULARIZATION;

RATTUS;

AGED; ANIMALS; ANTIGENS, CD; BLOOD VESSELS; CADHERINS; CELL ADHESION MOLECULES; CELL LINE, TUMOR; CLAUDINS; ENDOTHELIAL CELLS; FEMALE; GENE EXPRESSION REGULATION; HUMANS; INTERCELLULAR JUNCTIONS; LIVER; LIVER DISEASES; MALE; MEMBRANE PROTEINS; MIDDLE AGED; ORGAN SPECIFICITY; PROTEIN TRANSPORT; RATS; RATS, SPRAGUE-DAWLEY; TIGHT JUNCTIONS;

EID: 84859219929     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0034206     Document Type: Article

References (46)

1. Perri R, Shah V, (2005) Chapter 5: Hepatic Sinusoidal Endothelial Cells. In: Dufour JF, Clavien PA, editors. Signaling pathways in liver diseases Berlin Heidelberg Springer-Verlag pp. 53-62.
2. Si-Tayeb K, Lemaigre FP, Duncan SA, (2010) Organogenesis and development of the liver. Dev Cell 18: 175-189.
3. Aird WC, (2007) Phenotypic heterogeneity of the endothelium: II. Representative vascular beds. Circ Res 100: 174-190.
4. Steinhoff G, Behrend M, Schrader B, Duijvestijn AM, Wonigeit K, (1993) Expression patterns of leukocyte adhesion ligand molecules on human liver endothelia. Lack of ELAM-1 and CD62 inducibility on sinusoidal endothelia and distinct distribution of VCAM-1, ICAM-1, ICAM-2, and LFA-3. Am J Pathol 142: 481-488.
5. Lalor PF, Adams DH, (1999) Adhesion of lymphocytes to hepatic endothelium. Mol Pathol 52: 214-219.
6. Khandoga A, Huettinger S, Khandoga A, Li H, Butz S, et al. (2009) Leukocyte transmigration in inflamed liver: A role for endothelial cell-selective adhesion molecule. J Hepatol 50: 755-765.
7. Vekemans K, Braet F, (2005) Structural and functional aspects of the liver and liver sinusoidal cells in relation to colon carcinoma metastasis. World J Gastroenterol 11: 5095-5102.
8. Paschos K, Canovas D, Bird N, (2009) The role of cell adhesion molecules in the progression of colorectal cancer and the development of liver metastasis. Cell Signal 21: 665-674.
9. Braet F, Wisse E, (2002) Structural and functional aspects of liver sinusoidal endothelial cell fenestrae: a review. Comp Hepatol 1: 1.
10. Wisse E, De Zanger R, Charels K, Van Der Smissen P, McCuskey R, (1985) The liver sieve: considerations concerning the structure and function of endothelial fenestrae, the sinusoidal wall and the space of Disse. Hepatology 5: 683-692.
11. Tse D, Stan RV, (2010) Morphological heterogeneity of endothelium. Semin Thromb Hemost 36: 236-245.
12. Seternes T, Sørensen K, Smedsrød B, (2002) Scavenger endothelial cells of vertebrates: a nonperipheral leukocyte system for high-capacity elimination of waste macromolecules. Proc Natl Acad Sci U S A 99: 7594-7497.
13. Politz O, Gratchev A, McCourt P, Schledzewski K, Guillot P, et al. (2002) Stabilin-1 and-2 constitute a novel family of fasciclin-like hyaluronan receptor homologues. Biochem J 362: 155-164.
14. Schledzewski K, Géraud C, Arnold B, Wang S, Gröne HJ, et al. (2011) Deficiency of liver sinusoidal scavenger receptors stabilin-1 and-2 in mice causes glomerulofibrotic nephropathy via impaired hepatic clearance of noxious blood factors. J Clin Invest 121: 703-714.
15. Couvelard A, Scoazec JY, Feldmann G, (1993) Expression of cell-cell and cell-matrix adhesion proteins by sinusoidal endothelial cells in the normal and cirrhotic human liver. Am J Pathol 143: 738-752.
16. Gouysse G, Couvelard A, Frachon S, Bouvier R, Nejjari M, et al. (2002) Relationship between vascular development and vascular differentiation during liver organogenesis in humans. J Hepatol 37: 730-740.
17. Klein D, Demory A, Peyre F, Kroll J, Augustin HG, et al. (2008) Wnt2 acts as a cell type-specific, autocrine growth factor in rat hepatic sinusoidal endothelial cells cross-stimulating the VEGF pathway. Hepatology 47: 1018-1031.
18. March S, Hui E, Underhill G, Khetani S, Bhatia S, (2009) Microenvironmental regulation of the sinusoidal endothelial cell phenotype in vitro. Hepatology 50: 920-928.
19. Géraud C, Schledzewski K, Demory A, Klein D, Kaus M, et al. (2010) Liver sinusoidal endothelium: a microenvironment-dependent differentiation program in rat including the novel junctional protein liver endothelial differentiation-associated protein-1. Hepatology 52: 313-326.
20. Wisse E, (1970) An electron microscopic study of the fenestrated endothelial lining of rat liver sinusoids. J Ultrastructure Research 31: 125-150.
21. Wisse E, (1972) An ultrastructural characterization of the endothelial cell in the rat liver sinusoid under normal and various experimental conditions, as a contribution to the distinction between endothelial and Kupffer cells. J Ultrastructure Research 38: 528-562.
22. Tanuma Y, Ohata M, Ito T, (1983) Electron microscopic studies on the sinusoidal cells in the monkey liver. Arch Histol Jpn 46: 401-426.
23. Xu B, Broome U, Uzunel M, Nava S, Ge X, et al. (2003) Capillarization of hepatic sinusoid by liver endothelial cell-reactive autoantibodies in patients with cirrhosis and chronic hepatitis. Am J Pathol 163: 1275-1289.
24. Ding BS, Nolan DJ, Butler JM, James D, Babazadeh AO, et al. (2010) Inductive angiocrine signals from sinusoidal endothelium are required for liver regeneration. Nature 468: 310-315.
25. Medina J, Sanz-Cameno P, García-Buey L, Martín-Vílchez S, López-Cabrera M, et al. (2005) Evidence of angiogenesis in primary biliary cirrhosis: an immunohistochemical descriptive study. J Hepatol 42: 124-131.
26. Sakaguchi T, Suzuki S, Higashi H, Inaba K, Nakamura S, et al. (2008) Expression of tight junction protein claudin-5 in tumor vessels and sinusoidal endothelium in patients with hepatocellular carcinoma. J Surg Res 147: 123-131.
27. Palmeri D, van Zante A, Huang CC, Hemmerich S, Rosen SD, (2000) Vascular endothelial junction-associated molecule, a novel member of the immunoglobulin superfamily, is localized to intercellular boundaries of endothelial cells. J Biol Chem 275: 19139-19145.
28. Aurrand-Lions M, Johnson-Leger C, Wong C, Pasquier LD, Imhof BA, (2001) Heterogeneity of endothelial junctions is reflected by differential expression and specific subcellular localization of the three JAM family members. Blood 98: 3699-3707.
29. Scheiermann C, Colom B, Meda P, Patel N, Voisin M, et al. (2009) Junctional adhesion molecule-C mediates leukocyte infiltration in response to ischemia reperfusion injury. Arterioscler Thromb Vasc Biol 29: 1509-1515.
30. Lalor P, Lai W, Curbishley S, Shetty S, Adams D, (2006) Human hepatic sinusoidal endothelial cells can be distinguished by expression of phenotypic markers related to their specialised functions in vivo. World J Gastroenterol 12: 5429-5439.
31. Dejana E, Tournier-Lasserve E, Weinstein BM, (2009) The control of vascular integrity by endothelial cell junctions: molecular basis and pathological implications. Dev Cell 16: 209-221.
32. Baluk P, Fuxe J, Hashizume H, Romano T, Lashnits E, et al. (2007) Functionally specialized junctions between endothelial cells of lymphatic vessels. J Exp Med 204: 2349-2362.
33. Pfeiffer F, Kumar V, Butz S, Vestweber D, Imhof B, et al. (2008) Distinct molecular composition of blood and lymphatic vascular endothelial cell junctions establishes specific functional barriers within the peripheral lymph node. Eur J Immunol 38: 2142-2155.
34. Tsukita S, Katsuno T, Yamazaki Y, Umeda K, Tamura A, et al. (2009) Roles of ZO-1 and ZO-2 in establishment of the belt-like adherens and tight junctions with paracellular permselective barrier function. Ann N Y Acad Sci 1165: 44-52.
35. Katsuno T, Umeda K, Matsui T, Hata M, Tamura A, et al. (2008) Deficiency of zonula occludens-1 causes embryonic lethal phenotype associated with defected yolk sac angiogenesis and apoptosis of embryonic cells. Mol Biol Cell 19: 2465-2475.
36. Orlova V, Economopoulou M, Lupu F, Santoso S, Chavakis T, (2006) Junctional adhesion molecule-C regulates vascular endothelial permeability by modulating VE-cadherin-mediated cell-cell contacts. J Exp Med 203: 2703-2714.
37. Smedsrød B, Pertoft H, Eggertsen G, Sundström C, (1985) Functional and morphological characterization of cultures of Kupffer cells and liver endothelial cells prepared by means of density separation in Percoll, and selective substrate adherence. Cell Tissue Res 241: 639-649.
38. Li Q, Lau A, Morris TJ, Guo L, Fordyce CB, et al. (2004) A syntaxin 1, G alpha(o), and N-type calcium channel complex at a presynaptic nerve terminal: Analysis by quantitative immunocolocalization. Journal of Neuroscience 24: 4070-4081.
39. Carreira CM, Nasser SM, di Tomaso E, Padera TP, Boucher Y, et al. (2001) LYVE-1 is not restricted to the lymph vessels: Expression in normal liver blood sinusoids and down-regulation in human liver cancer and cirrhosis. Cancer Research 61: 8079-8084.
40. Elvevold K, Smedsrød B, Martinez I, (2008) The liver sinusoidal endothelial cell: a cell type of controversial and confusing identity. Am J Physiol Gastrointest Liver Physiol 294: G391-G400.
41. Nitta T, Hata M, Gotoh S, Seo Y, Sasaki H, et al. (2003) Size-selective loosening of the blood-brain barrier in claudin-5-deficient mice. J Cell Biol 161: 653-660.
42. Saitou M, Furuse M, Sasaki H, Schulzke J, Fromm M, et al. (2000) Complex phenotype of mice lacking occludin, a component of tight junction strands. Mol Biol Cell 11: 4131-4142.
43. Mandell K, Parkos C, (2005) The JAM family of proteins. Adv Drug Deliv Rev 57: 857-867.
44. Lim Y, Garcia-Cardena G, Allport J, Zervoglos M, Connolly A, et al. (2003) Heterogeneity of endothelial cells from different organ sites in T-cell subset recruitment. Am J Pathol 162: 1591-1601.
45. Anderson N, Anderson A, Wyllie R, (1976) Specialized structure and metabolic activities of high endothelial venules in rat lymphatic tissues. Immunology 31: 455-473.
46. Freemont A, Jones C, (1983) Light microscopic, histochemical and ultrastructural studies of human lymph node paracortical venules. J Anat 136: 349-362.