Deficiency of liver sinusoidal scavenger receptors stabilin-1 and -2 in mice causes glomerulofibrotic nephropathy via impaired hepatic clearance of noxious blood factors

Journal of Clinical Investigation

Volumn 121, Issue 2, 2011, Pages 703-714

  Schledzewski, Kai ^a   Géraud, Cyrill ^a   Arnold, Bernd ^b   Wang, Shijun ^b   Gröne, Hermann Josef ^b   Kempf, Tibor ^c   Wollert, Kai C ^c   Straub, Beate K ^d   Schirmacher, Peter ^d   Demory, Alexandra ^a   Schönhaber, Hiltrud ^a   Gratchev, Alexei ^a   Dietz, Lisa ^a   Thierse, Hermann Josef ^a   Kzhyshkowska, Julia ^a   Goerdt, Sergij ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^c HANNOVER MEDICAL SCHOOL   (Germany)

^d UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH DIFFERENTIATION FACTOR 15; SCAVENGER RECEPTOR; STABILIN 1; STABILIN 2; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE RESPONSE; DISEASE COURSE; DISEASE SEVERITY; ENDOTHELIUM CELL; FEMALE; GLOMERULOFIBROTIC NEPHROPATHY; KIDNEY DISEASE; KIDNEY TRANSPLANTATION; LIVER CLEARANCE; LIVER FIBROSIS; LIVER SINUSOID; MALE; MORTALITY; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION; WILD TYPE;

ANIMALS; CELL ADHESION MOLECULES, NEURONAL; COLLAGEN TYPE III; HUMANS; KIDNEY; KIDNEY DISEASES; LIVER; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; SURVIVAL RATE; TOXINS, BIOLOGICAL; TRANSFORMING GROWTH FACTOR BETA;

EID: 79551552424     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI44740     Document Type: Article

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