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Volumn 19, Issue 6, 2012, Pages 488-493

Marrubiin, a constituent of Leonotis leonurus, alleviates diabetic symptoms

Author keywords

Anti inflammatory; Antidiabetic; Hyperglycemia; Insulin; Leonotis leonurus; Marubiin

Indexed keywords

ACETYLSALICYLIC ACID; ANTIDIABETIC AGENT; ANTIINFLAMMATORY AGENT; GLUCOSE TRANSPORTER 2; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; LEONOTIS LEONURUS EXTRACT; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MARRUBIIN; METFORMIN; PLANT EXTRACT; SULFONYLUREA; UNCLASSIFIED DRUG;

EID: 84859217032     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2011.12.008     Document Type: Article
Times cited : (46)

References (27)
  • 1
    • 38149130672 scopus 로고    scopus 로고
    • Uncoupling protein-2 contributes significantly to high mitochondrial proton leak in INS-1E insulinoma cells and attenuates glucose-stimulated insulin secretion
    • C. Affourtit, and M.D. Brand Uncoupling protein-2 contributes significantly to high mitochondrial proton leak in INS-1E insulinoma cells and attenuates glucose-stimulated insulin secretion Biochemistry Journal 409 2008 199 204
    • (2008) Biochemistry Journal , vol.409 , pp. 199-204
    • Affourtit, C.1    Brand, M.D.2
  • 3
    • 80255125515 scopus 로고    scopus 로고
    • Combination of aspirin and metformin therapy may affect liver function tests and inflammatory mediators in experimentally diabetic rats
    • Y.M. Ashour, A.A.A. Khalil, and K.A. Abdel-Sater Combination of aspirin and metformin therapy may affect liver function tests and inflammatory mediators in experimentally diabetic rats Saudi German Hospitals Medical Journal 3 2009 25 34
    • (2009) Saudi German Hospitals Medical Journal , vol.3 , pp. 25-34
    • Ashour, Y.M.1    Khalil, A.A.A.2    Abdel-Sater, K.A.3
  • 4
    • 0018155445 scopus 로고
    • Critical evaluation of the potential error in pharmacokinetics studies of using the linear trapezoidal rule method for calculation of the area of the plasma level-time curve
    • W.C. Chiou Critical evaluation of the potential error in pharmacokinetics studies of using the linear trapezoidal rule method for calculation of the area of the plasma level-time curve Journal of Pharmacokinetics and Biopharmaceutics 6 1978 1 6
    • (1978) Journal of Pharmacokinetics and Biopharmaceutics , vol.6 , pp. 1-6
    • Chiou, W.C.1
  • 8
    • 10844286397 scopus 로고    scopus 로고
    • Clinical trial of Cecropia obstusifolia and Marrubium vulgare leaf extracts on blood glucose and serum lipids in type 2 diabetics
    • H. Herrera-Arellano, L. Aguilar-Santamaria, B. Garcia-Hernàndez, P. Nicasio-Torres, and J. Tortoriello Clinical trial of Cecropia obstusifolia and Marrubium vulgare leaf extracts on blood glucose and serum lipids in type 2 diabetics Phytomedicine 11 2004 561 566
    • (2004) Phytomedicine , vol.11 , pp. 561-566
    • Herrera-Arellano, H.1    Aguilar-Santamaria, L.2    Garcia-Hernàndez, B.3    Nicasio-Torres, P.4    Tortoriello, J.5
  • 9
    • 41849130581 scopus 로고    scopus 로고
    • The concept of precision extended to the atherogenic index of plasma
    • D.T. Holmes, J. Frohlich, and K.A. Buhr The concept of precision extended to the atherogenic index of plasma Clinical Biochemistry 41 2008 631 635
    • (2008) Clinical Biochemistry , vol.41 , pp. 631-635
    • Holmes, D.T.1    Frohlich, J.2    Buhr, K.A.3
  • 10
    • 33746880686 scopus 로고    scopus 로고
    • Antidiaebtic and antioxidant activity of Annona squamosa extract in streptozotocin-induced diabetic rats
    • M. Kaleem, F. Asif, Q.U. Ahmed, and B. Bano Antidiaebtic and antioxidant activity of Annona squamosa extract in streptozotocin-induced diabetic rats Singapore Medical Journal 47 2006 670 675
    • (2006) Singapore Medical Journal , vol.47 , pp. 670-675
    • Kaleem, M.1    Asif, F.2    Ahmed, Q.U.3    Bano, B.4
  • 11
    • 0030850424 scopus 로고    scopus 로고
    • Biosynthesis of the labdane diterepene marrubiin in Marrubium vulgare via a non-mevalonate pathway
    • W. Knöss, B. Reuter, and J. Zapp Biosynthesis of the labdane diterepene marrubiin in Marrubium vulgare via a non-mevalonate pathway Biochemical Journal 326 1997 449 454
    • (1997) Biochemical Journal , vol.326 , pp. 449-454
    • Knöss, W.1    Reuter, B.2    Zapp, J.3
  • 12
    • 1942424088 scopus 로고    scopus 로고
    • Natural medicines used in the traditional Chinese medical system for therapy of diabetes mellitus
    • W.L. Li, H.C. Zheng, J. Bukuru, and N. De Kimpe Natural medicines used in the traditional Chinese medical system for therapy of diabetes mellitus Journal of Ethnopharmacology 92 2004 1 21
    • (2004) Journal of Ethnopharmacology , vol.92 , pp. 1-21
    • Li, W.L.1    Zheng, H.C.2    Bukuru, J.3    De Kimpe, N.4
  • 14
    • 0035156817 scopus 로고    scopus 로고
    • Distinct effects of saturated and monosaturated fatty acids on β-cell turnover and function
    • K. Maedler, G.A. Spinas, D. Dyntar, W. Moritz, N. Kaiser, and M.Y. Donath Distinct effects of saturated and monosaturated fatty acids on β-cell turnover and function Diabetes 50 2001 69 76
    • (2001) Diabetes , vol.50 , pp. 69-76
    • Maedler, K.1    Spinas, G.A.2    Dyntar, D.3    Moritz, W.4    Kaiser, N.5    Donath, M.Y.6
  • 16
    • 57649188618 scopus 로고    scopus 로고
    • Hypoglycaemic treatment of type 2 diabetes: Targeting the endothelium
    • D. Nathanson, and T. Nyström Hypoglycaemic treatment of type 2 diabetes: targeting the endothelium Molecular and Cellular Endocrinology 297 2009 112 126
    • (2009) Molecular and Cellular Endocrinology , vol.297 , pp. 112-126
    • Nathanson, D.1    Nyström, T.2
  • 17
    • 18744375741 scopus 로고    scopus 로고
    • Antinociceptive, anti-inflammatory and antidiabetic effects of Leonotis leonurus (L.) R. BR. [Lamiaceae] leaf aqueous extracts in mice and rats
    • J.A.O. Ojewole Antinociceptive, anti-inflammatory and antidiabetic effects of Leonotis leonurus (L.) R. BR. [Lamiaceae] leaf aqueous extracts in mice and rats Methods and Findings in Experimental and Clinical Pharmacology 27 2005 257 268
    • (2005) Methods and Findings in Experimental and Clinical Pharmacology , vol.27 , pp. 257-268
    • Ojewole, J.A.O.1
  • 19
    • 37049057155 scopus 로고
    • The isolation of marrubiin from Leonotis leonurus R. Br
    • D.E.A. Rivett The isolation of marrubiin from Leonotis leonurus R. Br. Journal of Chemistry Society 1964 1857 1858
    • (1964) Journal of Chemistry Society , pp. 1857-1858
    • Rivett, D.E.A.1
  • 20
    • 79960451280 scopus 로고    scopus 로고
    • Rosiglitazone and pioglitazone aggravate doxorubicin-induced cardiomyopathy in Wistar rats
    • P. Saraogi, K.K. Pillai, B.K. Singh, and K. Dubey Rosiglitazone and pioglitazone aggravate doxorubicin-induced cardiomyopathy in Wistar rats Biomedicine and Aging Pathology 1 2011 65 71
    • (2011) Biomedicine and Aging Pathology , vol.1 , pp. 65-71
    • Saraogi, P.1    Pillai, K.K.2    Singh, B.K.3    Dubey, K.4
  • 21
    • 0017182018 scopus 로고
    • Dietary obesity in adult rats: Similarities to hypothalamic and human obesity syndromes
    • A. Sclafani, and D. Springer Dietary obesity in adult rats: similarities to hypothalamic and human obesity syndromes Physiological Behaviour 17 1976 461 471
    • (1976) Physiological Behaviour , vol.17 , pp. 461-471
    • Sclafani, A.1    Springer, D.2
  • 22
    • 4444376338 scopus 로고    scopus 로고
    • Genetic and environmental determinants of fibrin structure and function relevance to clinical disease
    • E.M. Scott, R.S.A. Ariens, and P.J. Grant Genetic and environmental determinants of fibrin structure and function relevance to clinical disease Arteriosclerosis, Thrombosis, and Vascular Biology 24 2004 1558 1566
    • (2004) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.24 , pp. 1558-1566
    • Scott, E.M.1    Ariens, R.S.A.2    Grant, P.J.3
  • 23
    • 40149105071 scopus 로고    scopus 로고
    • Insulin secretagogue effect of Ichnocarpus frutescence leaf extract in experimental diabetes: A dose-dependent study
    • P. Subash-Babu, S. Ignacimuthu, and P. Agastian Insulin secretagogue effect of Ichnocarpus frutescence leaf extract in experimental diabetes: a dose-dependent study Chemico-Biological Interactions 172 2008 159 171
    • (2008) Chemico-Biological Interactions , vol.172 , pp. 159-171
    • Subash-Babu, P.1    Ignacimuthu, S.2    Agastian, P.3
  • 24
    • 0037822245 scopus 로고    scopus 로고
    • Diabetes mellitus and multiple therapeutic approaches of phytochemicals: Present status and future prospects
    • A.K. Tiwari, and J.M. Rao Diabetes mellitus and multiple therapeutic approaches of phytochemicals: present status and future prospects Current Science 83 2002 30 38
    • (2002) Current Science , vol.83 , pp. 30-38
    • Tiwari, A.K.1    Rao, J.M.2
  • 27
    • 33744548069 scopus 로고    scopus 로고
    • Genipin inhibits UCP2-mediated proton leak and acutely reverses obesity-and high glucose-induced β-cell dysfunction in isolated pancreatic islets
    • C.-Y. Zhang, L.E. Parton, C.P. Ye, S. Krauss, R. Shen, C.-T. Lin, J.A. Porco Jr., and B. Lowell Genipin inhibits UCP2-mediated proton leak and acutely reverses obesity-and high glucose-induced β-cell dysfunction in isolated pancreatic islets Cell Metabolism 3 2006 417 427
    • (2006) Cell Metabolism , vol.3 , pp. 417-427
    • Zhang, C.-Y.1    Parton, L.E.2    Ye, C.P.3    Krauss, S.4    Shen, R.5    Lin, C.-T.6    Porco Jr., J.A.7    Lowell, B.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.